Platelet hyperreactivity and a prothrombotic phenotype in mice with a gain-of-function mutation in phospholipase Cγ2

Journal of Thrombosis and Haemostasis

Volumn 8, Issue 6, 2010, Pages 1353-1363

  Elvers, M ^a   Pozgaj, R ^a   Pleines, I ^a   May, F ^a   Kuijpers, M J E ^b   Heemskerk, J M W ^b   Yu, P ^c   Nieswandt, B ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Integrin; Platelet; PLC 2; Signaling; Thrombosis

Indexed keywords

ALPHA2BBETA3 INTEGRIN; C TYPE LECTIN LIKE RECEPTOR 2; COLLAGEN; GLYCOPROTEIN; GLYCOPROTEIN 6; INTEGRIN; LECTIN RECEPTOR; PHOSPHATIDYLSERINE; PHOSPHOLIPASE C GAMMA2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM MOBILIZATION; CELL SIZE; ENZYME ACTIVITY; LUNG EMBOLISM; MALE; MORTALITY; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; THROMBOCYTE COUNT; THROMBOGENESIS;

ANIMALS; BLOOD PLATELETS; FLOW CYTOMETRY; HETEROZYGOTE; MICE; MUTATION; PHENOTYPE; PHOSPHOLIPASE C GAMMA; PLATELET AGGREGATION; THROMBOSIS;

EID: 77954485876     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2010.03838.x     Document Type: Article

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