Disrupting the EMMPRIN (CD147)-cyclophilin a interaction reduces infarct size and preserves systolic function after myocardial ischemia and reperfusion

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 31, Issue 6, 2011, Pages 1377-1386

  Seizer, Peter ^a   Ochmann, Carmen ^a   Schönberger, Tanja ^a   Zach, Sebastian ^a   Rose, Melanie ^a   Borst, Oliver ^a,c   Klingel, Karin ^b   Kandolf, Reinhard ^b   MacDonald, H Robson ^d   Nowak, Romana A ^e   Engelhardt, Stefan ^f   Lang, Florian ^c   Gawaz, Meinrad ^a   May, Andreas E ^a  

^a Medizinische Klinik IV   (Germany)

^b Institut für Molekulare Pathologie   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d UNIVERSITY OF LAUSANNE   (Switzerland)

^e UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^f TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

coronary artery disease; EMMPRIN cyclophilin A; leukocytes; reperfusion injury

Indexed keywords

ABCAM; CD147 ANTIGEN; CYCLOPHILIN A; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD147; MONOCLONAL ANTIBODY HB 189; PHOSPHATIDYLINOSITOL 3 KINASE; UNCLASSIFIED DRUG;

ACUTE HEART INFARCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; CHEMOTAXIS; CONTROLLED STUDY; FLOW CYTOMETRY; HEART INFARCTION SIZE; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MONOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REPERFUSION INJURY; SYSTOLIC BLOOD PRESSURE; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; ANTIGENS, CD147; CELL ADHESION; CELL MOVEMENT; CYCLOPHILIN A; HUMANS; MACROPHAGES; MICE; MICE, INBRED C57BL; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; NEUTROPHILS; SYSTOLE;

EID: 79957466991     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.111.225771     Document Type: Article

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