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Volumn 78, Issue 14, 2012, Pages 1549-1555

Gingerols of zingiber officinale enhance glucose uptake by increasing cell surface GLUT4 in cultured L6 myotubes

Author keywords

gingerols; glucose uptake; GLUT4; L6 myotube; type 2 diabetes; Zingiber officinale (Zingiberaceae)

Indexed keywords

(10) GINGEROL; (6) GINGEROL; (8) GINGEROL; BETA ACTIN; CELL MEMBRANE PROTEIN; CELL SURFACE RECEPTOR; EPITOPE; GLUCOSE; GLUCOSE TRANSPORTER 4; HEMAGGLUTININ; METFORMIN; SHOGAOL;

EID: 84867080446     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0032-1315041     Document Type: Article
Times cited : (106)

References (32)
  • 1
    • 0034796238 scopus 로고    scopus 로고
    • Contribution to glucose tolerance of insulin-independent vs. insulin-dependent mechanisms in mice
    • Pacini G., Thomaseth K., Ahren B. Contribution to glucose tolerance of insulin-independent vs. insulin-dependent mechanisms in mice. Am J Physiol Endocrinol Metab: 2001; 281 E693 E703
    • (2001) Am J Physiol Endocrinol Metab , vol.281
    • Pacini, G.1    Thomaseth, K.2    Ahren, B.3
  • 2
    • 33745815985 scopus 로고    scopus 로고
    • AMP-activated protein kinase signaling in metabolic regulation
    • DOI 10.1172/JCI29044
    • Long Y. C., Zierath J. R. AMP-activated protein kinase signaling in metabolic regulation. J Clin Invest: 2006; 116 1776 1783 (Pubitemid 44033297)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.7 , pp. 1776-1783
    • Yun, C.L.1    Zierath, J.R.2
  • 3
    • 0021994683 scopus 로고
    • Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus
    • DeFronzo R. A., Gunnarsson R., Bjorkman O., Olsson M., Wahren J. Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus. J Clin Invest: 1985; 76 149 155 (Pubitemid 15240430)
    • (1985) Journal of Clinical Investigation , vol.76 , Issue.1 , pp. 149-155
    • DeFronzo, R.A.1    Gunnarsson, R.2    Bjorkman, O.3
  • 4
    • 0024237258 scopus 로고
    • Rates and tissue sites of non-insulin- and insulin-mediated glucose uptake in humans
    • Baron A. D., Brechtel G., Wallace P., Edelman S. V. Rates and tissue sites of non-insulin- and insulin-mediated glucose uptake in humans. Am J Physiol: 1988; 255 E769 E774
    • (1988) Am J Physiol , vol.255
    • Baron, A.D.1    Brechtel, G.2    Wallace, P.3    Edelman, S.V.4
  • 5
    • 0022622231 scopus 로고
    • Rate-limiting steps for insulin-mediated glucose uptake into perfused rat hindlimb
    • Kubo K., Foley J. E. Rate-limiting steps for insulin-mediated glucose uptake into perfused rat hindlimb. Am J Physiol: 1986; 250 E100 E102
    • (1986) Am J Physiol , vol.250
    • Kubo, K.1    Foley, J.E.2
  • 8
    • 0032104120 scopus 로고    scopus 로고
    • Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance
    • Garvey W. T., Maianu L., Zhu J. H., Brechtel-Hook G., Wallace P., Baron A. D. Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance. J Clin Invest: 1998; 101 2377 2386 (Pubitemid 28270432)
    • (1998) Journal of Clinical Investigation , vol.101 , Issue.11 , pp. 2377-2386
    • Garvey, W.T.1    Maianu, L.2    Zhu, J.-H.3    Brechtel-Hook, G.4    Wallace, P.5    Baron, A.D.6
  • 11
    • 0035039274 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise
    • Musi N., Fujii N., Hirshman M. F., Ekberg I., Froberg S., Ljungqvist O., Thorell A., Goodyear L. J. AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise. Diabetes: 2001; 50 921 927 (Pubitemid 32374520)
    • (2001) Diabetes , vol.50 , Issue.5 , pp. 921-927
    • Musi, N.1    Fujii, N.2    Hirshman, M.F.3    Ekberg, I.4    Froberg, S.5    Ljungqvist, O.6    Thorell, A.7    Goodyear, L.J.8
  • 12
    • 37349127807 scopus 로고    scopus 로고
    • Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research
    • DOI 10.1016/j.fct.2007.09.085, PII S0278691507004243
    • Ali B. H., Blunden G., Tanira M. O., Nemmar A. Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research. Food Chem Toxicol: 2008; 46 409 420 (Pubitemid 350297543)
    • (2008) Food and Chemical Toxicology , vol.46 , Issue.2 , pp. 409-420
    • Ali, B.H.1    Blunden, G.2    Tanira, M.O.3    Nemmar, A.4
  • 13
    • 23844530273 scopus 로고    scopus 로고
    • Zingiberis rhizoma: A comprehensive review on the ginger effect and efficacy profiles
    • DOI 10.1016/j.phymed.2004.07.009, PII S0944711305001248
    • Chrubasik S., Pittler M. H., Roufogalis B. D. Zingiberis rhizoma: a comprehensive review on the ginger effect and efficacy profiles. Phytomedicine: 2005; 12 684 701 (Pubitemid 41169818)
    • (2005) Phytomedicine , vol.12 , Issue.9 , pp. 684-701
    • Chrubasik, S.1    Pittler, M.H.2    Roufogalis, B.D.3
  • 14
    • 64549145497 scopus 로고    scopus 로고
    • Protective effects of ethanolic extract of Zingiber officinale rhizome on the development of metabolic syndrome in high-fat diet-fed rats
    • Nammi S., Sreemantula S., Roufogalis B. D. Protective effects of ethanolic extract of Z ingiber officinale rhizome on the development of metabolic syndrome in high-fat diet-fed rats. J Basic Clin Pharmacol Toxicol: 2009; 104 366 373
    • (2009) J Basic Clin Pharmacol Toxicol , vol.104 , pp. 366-373
    • Nammi, S.1    Sreemantula, S.2    Roufogalis, B.D.3
  • 15
    • 33748783056 scopus 로고    scopus 로고
    • Analgesic, antiinflammatory and hypoglycaemic effects of ethanol extract of Zingiber officinale (Roscoe) rhizomes (Zingiberaceae) in mice and rats
    • DOI 10.1002/ptr.1952
    • Ojewole J. A. Analgesic, antiinflammatory and hypoglycaemic effects of ethanol extract of Zingiber officinale (Roscoe) rhizomes (Zingiberaceae) in mice and rats. Phytother Res: 2006; 20 764 772 (Pubitemid 44408657)
    • (2006) Phytotherapy Research , vol.20 , Issue.9 , pp. 764-772
    • Ojewole, J.A.O.1
  • 16
    • 33947274715 scopus 로고    scopus 로고
    • Anti-diabetic and hypolipidaemic properties of ginger (Zingiber officinale) in streptozotocin-induced diabetic rats
    • DOI 10.1079/BJN20061849
    • Al-Amin Z. M., Thomson M., Al-Qattan K. K., Peltonen-Shalaby R., Ali M. Anti-diabetic and hypolipidaemic properties of ginger (Zingiber officinale) in streptozotocin-induced diabetic rats. Br J Nutr: 2006; 96 660 666 (Pubitemid 46470189)
    • (2006) British Journal of Nutrition , vol.96 , Issue.4 , pp. 660-666
    • Al-Amin, Z.M.1    Thomson, M.2    Al-Qattan, K.K.3    Ali, M.4
  • 17
    • 77955092956 scopus 로고    scopus 로고
    • Enhancement of glucose transport by selected plant foods in muscle cell line L6
    • Noipha K., Ratanachaiyavong S., Ninla-Aesong P. Enhancement of glucose transport by selected plant foods in muscle cell line L6. Diabetes Res Clin Pract: 2010; 89 e22 e26
    • (2010) Diabetes Res Clin Pract , vol.89
    • Noipha, K.1    Ratanachaiyavong, S.2    Ninla-Aesong, P.3
  • 18
    • 0035574475 scopus 로고    scopus 로고
    • Effect of ginger constituents and synthetic analogues on cyclooxygenase-2 enzyme in intact cells
    • DOI 10.1006/bioo.2001.1208
    • Tjendraputra E., Tran V. H., Liu-Brennan D., Roufogalis B. D., Duke C. C. Effect of ginger constituents and synthetic analogues on cyclooxygenase-2 enzyme in intact cells. Bioorg Chem: 2001; 29 156 163 (Pubitemid 34226237)
    • (2001) Bioorganic Chemistry , vol.29 , Issue.3 , pp. 156-163
    • Tjendraputra, E.1    Tran, V.H.2    Liu-Brennan, D.3    Roufogalis, B.D.4    Duke, C.C.5
  • 19
    • 84861968349 scopus 로고    scopus 로고
    • Zingiber officinale extract exhibits antidiabetic potential via modulating glucose uptake, protein glycation and inhibiting adipocyte differentiation: An in vitro study
    • Rani M. P., Krishna M. S., Padmakumari K. P., Raghu K. G., Sundaresan A. Zingiber officinale extract exhibits antidiabetic potential via modulating glucose uptake, protein glycation and inhibiting adipocyte differentiation: an in vitro study. J Sci Food Agric: 2012; 92 1948 1955
    • (2012) J Sci Food Agric , vol.92 , pp. 1948-1955
    • Rani, M.P.1    Krishna, M.S.2    Padmakumari, K.P.3    Raghu, K.G.4    Sundaresan, A.5
  • 20
    • 21844465655 scopus 로고    scopus 로고
    • 2 production
    • DOI 10.1016/j.phytochem.2005.05.007, PII S0031942205002244
    • Jolad S. D., Lantz R. C., Chen G. J., Bates R. B., Timmermann B. N. Commercially processed dry ginger (Zingiber officinale): composition and effects on LPS-stimulated PGE2 production. Phytochemistry: 2005; 66 1614 1635 (Pubitemid 40950555)
    • (2005) Phytochemistry , vol.66 , Issue.13 , pp. 1614-1635
    • Jolad, S.D.1    Lantz, R.C.2    Guan, J.C.3    Bates, R.B.4    Timmermann, B.N.5
  • 21
    • 84856560488 scopus 로고    scopus 로고
    • [6]-Gingerol isolated from ginger attenuates sodium arsenite induced oxidative stress and plays a corrective role in improving insulin signaling in mice
    • Chakraborty D., Mukherjee A., Sikdar S., Paul A., Ghosh S., Khuda-Bukhsh A. R. [6]-Gingerol isolated from ginger attenuates sodium arsenite induced oxidative stress and plays a corrective role in improving insulin signaling in mice. Toxicol Lett: 2012; 210 34 43
    • (2012) Toxicol Lett , vol.210 , pp. 34-43
    • Chakraborty, D.1    Mukherjee, A.2    Sikdar, S.3    Paul, A.4    Ghosh, S.5    Khuda-Bukhsh, A.R.6
  • 22
    • 76249115787 scopus 로고    scopus 로고
    • Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes
    • Fazakerley D. J., Holman G. D., Marley A., James D. E., Stockli J., Coster A. C. Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes. J Biol Chem: 2010; 285 1653 1660
    • (2010) J Biol Chem , vol.285 , pp. 1653-1660
    • Fazakerley, D.J.1    Holman, G.D.2    Marley, A.3    James, D.E.4    Stockli, J.5    Coster, A.C.6
  • 23
    • 73749083481 scopus 로고    scopus 로고
    • Global estimates of the prevalence of diabetes for 2010 and 2030
    • Shaw J. E., Sicree R. A., Zimmet P. Z. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract: 2010; 87 4 14
    • (2010) Diabetes Res Clin Pract , vol.87 , pp. 4-14
    • Shaw, J.E.1    Sicree, R.A.2    Zimmet, P.Z.3
  • 24
    • 13644263258 scopus 로고    scopus 로고
    • Oral antidiabetic agents: Current role in type 2 diabetes mellitus
    • DOI 10.2165/00003495-200565030-00005
    • Krentz A. J., Bailey C. J. Oral antidiabetic agents: current role in type 2 diabetes mellitus. Drugs: 2005; 65 385 411 (Pubitemid 40227460)
    • (2005) Drugs , vol.65 , Issue.3 , pp. 385-411
    • Krentz, A.J.1    Bailey, C.J.2
  • 25
    • 28844458471 scopus 로고    scopus 로고
    • Beneficial effects of Zingiber officinale Roscoe on fructose induced hyperlipidemia and hyperinsulinemia in rats
    • Kadnur S. V., Goyal R. K. Beneficial effects of Zingiber officinale Roscoe on fructose induced hyperlipidemia and hyperinsulinemia in rats. Indian J Exp Biol: 2005; 43 1161 1164 (Pubitemid 41769216)
    • (2005) Indian Journal of Experimental Biology , vol.43 , Issue.12 , pp. 1161-1164
    • Kadnur, S.V.1    Goyal, R.K.2
  • 26
    • 59849106109 scopus 로고    scopus 로고
    • Plasma pharmacokinetics and tissue distribution of [6]-gingerol in rats
    • Jiang S. Z., Wang N. S., Mi S. Q. Plasma pharmacokinetics and tissue distribution of [6]-gingerol in rats. Biopharm Drug Dispos: 2008; 29 529 537
    • (2008) Biopharm Drug Dispos , vol.29 , pp. 529-537
    • Jiang, S.Z.1    Wang, N.S.2    Mi, S.Q.3
  • 27
    • 29944440188 scopus 로고    scopus 로고
    • 3 receptors: Binding studies, cation uptake by the receptor channel and contraction of isolated guinea-pig ileum
    • DOI 10.1016/j.ejphar.2005.10.049, PII S0014299905011179
    • Abdel-Aziz H., Windeck T., Ploch M., Verspohl E. J. Mode of action of gingerols and shogaols on 5-HT3 receptors: binding studies, cation uptake by the receptor channel and contraction of isolated guinea-pig ileum. Eur J Pharmacol: 2006; 530 136 143 (Pubitemid 43040002)
    • (2006) European Journal of Pharmacology , vol.530 , Issue.1-2 , pp. 136-143
    • Abdel-Aziz, H.1    Windeck, T.2    Ploch, M.3    Verspohl, E.J.4
  • 28
    • 0345802676 scopus 로고    scopus 로고
    • Effective anti-platelet and COX-1 enzyme inhibitors from pungent constituents of ginger
    • DOI 10.1016/j.thromres.2003.09.009
    • Nurtjahja-Tjendraputra E., Ammit A. J., Roufogalis B. D., Tran V. H., Duke C. C. Effective anti-platelet and COX-1 enzyme inhibitors from pungent constituents of ginger. Thromb Res: 2003; 111 259 265 (Pubitemid 38021945)
    • (2003) Thrombosis Research , vol.111 , Issue.4-5 , pp. 259-265
    • Nurtjahja-Tjendraputra, E.1    Ammit, A.J.2    Roufogalis, B.D.3    Tran, V.H.4    Duke, C.C.5
  • 29
    • 0023882706 scopus 로고
    • Insulin-regulatable tissues express a unique insulin-sensitive glucose transport protein
    • James D. E., Brown R., Navarro J., Pilch P. F. Insulin-regulatable tissues express a unique insulin-sensitive glucose transport protein. Nature: 1988; 333 183 185
    • (1988) Nature , vol.333 , pp. 183-185
    • James, D.E.1    Brown, R.2    Navarro, J.3    Pilch, P.F.4
  • 30
    • 67651237066 scopus 로고    scopus 로고
    • The many ways to regulate glucose transporter 4
    • Klip A. The many ways to regulate glucose transporter 4. Appl Physiol Nutr Metab: 2009; 34 481 487
    • (2009) Appl Physiol Nutr Metab , vol.34 , pp. 481-487
    • Klip, A.1
  • 31
    • 27844435600 scopus 로고    scopus 로고
    • Minireview: Recent developments in the regulation of glucose transporter-4 traffic: New signals, locations, and partners
    • DOI 10.1210/en.2005-0850
    • Ishiki M., Klip A. Minireview: recent developments in the regulation of glucose transporter-4 traffic: new signals, locations, and partners. Endocrinology: 2005; 146 5071 5078 (Pubitemid 41653019)
    • (2005) Endocrinology , vol.146 , Issue.12 , pp. 5071-5078
    • Ishiki, M.1    Klip, A.2
  • 32
    • 33947596679 scopus 로고    scopus 로고
    • The GLUT4 Glucose Transporter
    • DOI 10.1016/j.cmet.2007.03.006, PII S1550413107000678
    • Huang S., Czech M. P. The GLUT4 glucose transporter. Cell Metab: 2007; 5 237 252 (Pubitemid 46477860)
    • (2007) Cell Metabolism , vol.5 , Issue.4 , pp. 237-252
    • Huang, S.1    Czech, M.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.