메뉴 건너뛰기




Volumn 7, Issue 10, 2012, Pages

A Cardiac-Specific Robotized Cellular Assay Identified Families of Human Ligands as Inducers of PGC-1α Expression and Mitochondrial Biogenesis

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; LIGAND; LUCIFERASE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; STEROID HORMONE; VITAMIN B GROUP;

EID: 84867074297     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046753     Document Type: Article
Times cited : (17)

References (54)
  • 1
    • 84856470679 scopus 로고    scopus 로고
    • PGC-1 coactivators in the cardiovascular system
    • Patten IS, Arany Z, (2011) PGC-1 coactivators in the cardiovascular system. Trends Endocrinol Metab 2: 90-97.
    • (2011) Trends Endocrinol Metab , vol.2 , pp. 90-97
    • Patten, I.S.1    Arany, Z.2
  • 2
    • 0141634243 scopus 로고    scopus 로고
    • Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles
    • Garnier A, Fortin D, Delomenie C, Momken I, Veksler V, et al. (2003) Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles. J Physiol 551: 491-501.
    • (2003) J Physiol , vol.551 , pp. 491-501
    • Garnier, A.1    Fortin, D.2    Delomenie, C.3    Momken, I.4    Veksler, V.5
  • 3
    • 33746714417 scopus 로고    scopus 로고
    • ACE inhibition prevents myocardial infarction-induced skeletal muscle mitochondrial dysfunction
    • Zoll J, Monassier L, Garnier A, N'Guessan B, Mettauer B, et al. (2006) ACE inhibition prevents myocardial infarction-induced skeletal muscle mitochondrial dysfunction. J Appl Physiol 101: 385-91.
    • (2006) J Appl Physiol , vol.101 , pp. 385-391
    • Zoll, J.1    Monassier, L.2    Garnier, A.3    N'Guessan, B.4    Mettauer, B.5
  • 4
    • 79751524476 scopus 로고    scopus 로고
    • Induction of heart failure by minimally invasive aortic constriction in mice: reduced peroxisome proliferator-activated receptor gamma coactivator levels and mitochondrial dysfunction
    • Faerber G, Barreto-Perreia F, Schoepe M, Gilsbach R, Schrepper A, et al. (2011) Induction of heart failure by minimally invasive aortic constriction in mice: reduced peroxisome proliferator-activated receptor gamma coactivator levels and mitochondrial dysfunction. J Thorac Cardiovasc Surg 141: 492-500, 500.e1.
    • (2011) J Thorac Cardiovasc Surg , vol.141
    • Faerber, G.1    Barreto-Perreia, F.2    Schoepe, M.3    Gilsbach, R.4    Schrepper, A.5
  • 5
    • 34648837687 scopus 로고    scopus 로고
    • Induction of mitochondrial biogenesis is a maladaptive mechanism in mitochondrial cardiomyopathies
    • Sebastiani M, Giordano C, Nediani C, Travaglini C, Borchi E, et al. (2007) Induction of mitochondrial biogenesis is a maladaptive mechanism in mitochondrial cardiomyopathies. J Am Coll Cardiol 50: 1362-9.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1362-1369
    • Sebastiani, M.1    Giordano, C.2    Nediani, C.3    Travaglini, C.4    Borchi, E.5
  • 6
    • 77952430578 scopus 로고    scopus 로고
    • Control by circulating factors of mitochondrial function and transcription cascade in heart failure: a role for endothelin-1 and angiotensin II
    • Garnier A, Zoll J, Fortin D, N'Guessan B, Lefebvre F, et al. (2009) Control by circulating factors of mitochondrial function and transcription cascade in heart failure: a role for endothelin-1 and angiotensin II. Circ Heart Fail 2: 342-50.
    • (2009) Circ Heart Fail , vol.2 , pp. 342-350
    • Garnier, A.1    Zoll, J.2    Fortin, D.3    N'Guessan, B.4    Lefebvre, F.5
  • 7
    • 77952428203 scopus 로고    scopus 로고
    • Defective DNA replication impairs mitochondrial biogenesis in human failing hearts
    • Karamanlidis G, Nascimben L, Couper GS, Shekar PS, del Monte F, et al. (2010) Defective DNA replication impairs mitochondrial biogenesis in human failing hearts. Circ Res 106: 1541-8.
    • (2010) Circ Res , vol.106 , pp. 1541-1548
    • Karamanlidis, G.1    Nascimben, L.2    Couper, G.S.3    Shekar, P.S.4    del Monte, F.5
  • 8
    • 80053562936 scopus 로고    scopus 로고
    • AMP activated protein kinase-alpha2 regulates expression of estrogen-related receptor-alpha, a metabolic transcription factor related to heart failure development
    • Hu X, Xu X, Lu Z, Zhang P, Fassett J, et al. (2011) AMP activated protein kinase-alpha2 regulates expression of estrogen-related receptor-alpha, a metabolic transcription factor related to heart failure development. Hypertension 58: 696-703.
    • (2011) Hypertension , vol.58 , pp. 696-703
    • Hu, X.1    Xu, X.2    Lu, Z.3    Zhang, P.4    Fassett, J.5
  • 9
    • 35348969404 scopus 로고    scopus 로고
    • Targeting PGC-1 alpha to control energy homeostasis
    • Wu Z, Boss O, (2007) Targeting PGC-1 alpha to control energy homeostasis. Expert Opin Ther Targets 11: 1329-38.
    • (2007) Expert Opin Ther Targets , vol.11 , pp. 1329-1338
    • Wu, Z.1    Boss, O.2
  • 11
    • 0347993714 scopus 로고    scopus 로고
    • PGC-1alpha mRNA expression is influenced by metabolic perturbation in exercising human skeletal muscle
    • Norrbom J, Sundberg CJ, Ameln H, Kraus WE, Jansson E, et al. (2004) PGC-1alpha mRNA expression is influenced by metabolic perturbation in exercising human skeletal muscle. J Appl Physiol 96: 189-94.
    • (2004) J Appl Physiol , vol.96 , pp. 189-194
    • Norrbom, J.1    Sundberg, C.J.2    Ameln, H.3    Kraus, W.E.4    Jansson, E.5
  • 12
    • 79953232671 scopus 로고    scopus 로고
    • Exercise increases mitochondrial PGC-1alpha content and promotes nuclear-mitochondrial cross-talk to coordinate mitochondrial biogenesis
    • Safdar A, Little JP, Stokl AJ, Hettinga BP, Akhtar M, et al. (2011) Exercise increases mitochondrial PGC-1alpha content and promotes nuclear-mitochondrial cross-talk to coordinate mitochondrial biogenesis. J Biol Chem 286: 10605-17.
    • (2011) J Biol Chem , vol.286 , pp. 10605-10617
    • Safdar, A.1    Little, J.P.2    Stokl, A.J.3    Hettinga, B.P.4    Akhtar, M.5
  • 14
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • Puigserver P, Wu Z, Park CW, Graves R, Wright M, et al. (1998) A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92: 829-39.
    • (1998) Cell , vol.92 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3    Graves, R.4    Wright, M.5
  • 15
    • 79953210362 scopus 로고    scopus 로고
    • Regulation of PGC-1alpha, a nodal regulator of mitochondrial biogenesis
    • Fernandez-Marcos PJ, Auwerx J, (2011) Regulation of PGC-1alpha, a nodal regulator of mitochondrial biogenesis. Am J Clin Nutr 93: 884S-90.
    • (2011) Am J Clin Nutr , vol.93 , pp. 8840-8890
    • Fernandez-Marcos, P.J.1    Auwerx, J.2
  • 16
    • 11244315114 scopus 로고    scopus 로고
    • Coordinated changes in mitochondrial function and biogenesis in healthy and diseased human skeletal muscle
    • Garnier A, Fortin D, Zoll J, N'Guessan B, Mettauer B, et al. (2005) Coordinated changes in mitochondrial function and biogenesis in healthy and diseased human skeletal muscle. FASEB J 19: 43-52.
    • (2005) FASEB J , vol.19 , pp. 43-52
    • Garnier, A.1    Fortin, D.2    Zoll, J.3    N'Guessan, B.4    Mettauer, B.5
  • 17
  • 18
    • 33845399894 scopus 로고    scopus 로고
    • Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha
    • Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, et al. (2006) Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell 127: 1109-22.
    • (2006) Cell , vol.127 , pp. 1109-1122
    • Lagouge, M.1    Argmann, C.2    Gerhart-Hines, Z.3    Meziane, H.4    Lerin, C.5
  • 19
    • 26844558334 scopus 로고    scopus 로고
    • Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
    • Nisoli E, Tonello C, Cardile A, Cozzi V, Bracale R, et al. (2005) Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science 310: 314-7.
    • (2005) Science , vol.310 , pp. 314-317
    • Nisoli, E.1    Tonello, C.2    Cardile, A.3    Cozzi, V.4    Bracale, R.5
  • 20
    • 21144446106 scopus 로고    scopus 로고
    • PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis
    • Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, et al. (2005) PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol 3: e101.
    • (2005) PLoS Biol , vol.3
    • Leone, T.C.1    Lehman, J.J.2    Finck, B.N.3    Schaeffer, P.J.4    Wende, A.R.5
  • 21
    • 49849085702 scopus 로고    scopus 로고
    • The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis
    • Lehman JJ, Boudina S, Banke NH, Sambandam N, Han X, et al. (2008) The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis. Am J Physiol Heart Circ Physiol 295: H185-96.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Lehman, J.J.1    Boudina, S.2    Banke, N.H.3    Sambandam, N.4    Han, X.5
  • 22
    • 22144434964 scopus 로고    scopus 로고
    • Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle
    • Arany Z, He H, Lin J, Hoyer K, Handschin C, et al. (2005) Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle. Cell Metab 1: 259-71.
    • (2005) Cell Metab , vol.1 , pp. 259-271
    • Arany, Z.1    He, H.2    Lin, J.3    Hoyer, K.4    Handschin, C.5
  • 23
    • 79960926626 scopus 로고    scopus 로고
    • Methods in cardiomyocyte isolation, culture, and gene transfer
    • Louch WE, Sheehan KA, Wolska BM, (2011) Methods in cardiomyocyte isolation, culture, and gene transfer. J Mol Cell Cardiol 51: 288-98.
    • (2011) J Mol Cell Cardiol , vol.51 , pp. 288-298
    • Louch, W.E.1    Sheehan, K.A.2    Wolska, B.M.3
  • 24
    • 42449092519 scopus 로고    scopus 로고
    • Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1alpha and oxidative phosphorylation
    • Arany Z, Wagner BK, Ma Y, Chinsomboon J, Laznik D, et al. (2008) Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1alpha and oxidative phosphorylation. Proc Natl Acad Sci U S A 105: 4721-6.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 4721-4726
    • Arany, Z.1    Wagner, B.K.2    Ma, Y.3    Chinsomboon, J.4    Laznik, D.5
  • 25
    • 0142036803 scopus 로고    scopus 로고
    • Modulation of L-type calcium channel expression during retinoic acid-induced differentiation of H9C2 cardiac cells
    • Menard C, Pupier S, Mornet D, Kitzmann M, Nargeot J, et al. (1999) Modulation of L-type calcium channel expression during retinoic acid-induced differentiation of H9C2 cardiac cells. J Biol Chem 274: 29063-70.
    • (1999) J Biol Chem , vol.274 , pp. 29063-29070
    • Menard, C.1    Pupier, S.2    Mornet, D.3    Kitzmann, M.4    Nargeot, J.5
  • 26
    • 84863250273 scopus 로고    scopus 로고
    • Interferons induce the expression of IFITM1 and IFITM3 and suppress the proliferation of rat neonatal cardiomyocytes
    • Lau SL, Yuen ML, Kou CY, Au KW, Zhou J, et al. (2012) Interferons induce the expression of IFITM1 and IFITM3 and suppress the proliferation of rat neonatal cardiomyocytes. J Cell Biochem 113: 841-7.
    • (2012) J Cell Biochem , vol.113 , pp. 841-847
    • Lau, S.L.1    Yuen, M.L.2    Kou, C.Y.3    Au, K.W.4    Zhou, J.5
  • 27
    • 0038810035 scopus 로고    scopus 로고
    • An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle
    • Handschin C, Rhee J, Lin J, Tarr PT, Spiegelman BM, (2003) An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle. Proc Natl Acad Sci U S A 100: 7111-6.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 7111-7116
    • Handschin, C.1    Rhee, J.2    Lin, J.3    Tarr, P.T.4    Spiegelman, B.M.5
  • 28
    • 58349095060 scopus 로고    scopus 로고
    • AMP-activated protein kinase-regulated activation of the PGC-1alpha promoter in skeletal muscle cells
    • Irrcher I, Ljubicic V, Kirwan AF, Hood DA, (2008) AMP-activated protein kinase-regulated activation of the PGC-1alpha promoter in skeletal muscle cells. PLoS One 3: e3614.
    • (2008) PLoS One , vol.3
    • Irrcher, I.1    Ljubicic, V.2    Kirwan, A.F.3    Hood, D.A.4
  • 29
    • 64749115463 scopus 로고    scopus 로고
    • Gaussia luciferase reporter assay for monitoring biological processes in culture and in vivo
    • Tannous BA, (2009) Gaussia luciferase reporter assay for monitoring biological processes in culture and in vivo. Nat Protoc 4: 582-91.
    • (2009) Nat Protoc , vol.4 , pp. 582-591
    • Tannous, B.A.1
  • 30
    • 49749108197 scopus 로고    scopus 로고
    • Sex-specific pathways in early cardiac response to pressure overload in mice
    • Witt H, Schubert C, Jaekel J, Fliegner D, Penkalla A, et al. (2008) Sex-specific pathways in early cardiac response to pressure overload in mice. J Mol Med (Berl) 86: 1013-24.
    • (2008) J Mol Med (Berl) , vol.86 , pp. 1013-1024
    • Witt, H.1    Schubert, C.2    Jaekel, J.3    Fliegner, D.4    Penkalla, A.5
  • 31
    • 33750001533 scopus 로고    scopus 로고
    • Mitochondrial function and toxicity: role of B vitamins on the one-carbon transfer pathways
    • Depeint F, Bruce WR, Shangari N, Mehta R, O'Brien PJ, (2006) Mitochondrial function and toxicity: role of B vitamins on the one-carbon transfer pathways. Chem Biol Interact 163: 113-32.
    • (2006) Chem Biol Interact , vol.163 , pp. 113-132
    • Depeint, F.1    Bruce, W.R.2    Shangari, N.3    Mehta, R.4    O'Brien, P.J.5
  • 32
    • 77958021516 scopus 로고    scopus 로고
    • PGC-1 coactivators in cardiac development and disease
    • Rowe GC, Jiang A, Arany Z, (2010) PGC-1 coactivators in cardiac development and disease. Circ Res 107: 825-38.
    • (2010) Circ Res , vol.107 , pp. 825-838
    • Rowe, G.C.1    Jiang, A.2    Arany, Z.3
  • 33
    • 42049114034 scopus 로고    scopus 로고
    • Transcriptional paradigms in mammalian mitochondrial biogenesis and function
    • Scarpulla RC, (2008) Transcriptional paradigms in mammalian mitochondrial biogenesis and function. Physiol Rev 88: 611-38.
    • (2008) Physiol Rev , vol.88 , pp. 611-638
    • Scarpulla, R.C.1
  • 34
    • 0033105510 scopus 로고    scopus 로고
    • Molecular recognition of fatty acids by peroxisome proliferator-activated receptors
    • Xu HE, Lambert MH, Montana VG, Parks DJ, Blanchard SG, et al. (1999) Molecular recognition of fatty acids by peroxisome proliferator-activated receptors. Mol Cell 3: 397-403.
    • (1999) Mol Cell , vol.3 , pp. 397-403
    • Xu, H.E.1    Lambert, M.H.2    Montana, V.G.3    Parks, D.J.4    Blanchard, S.G.5
  • 35
    • 34547505089 scopus 로고    scopus 로고
    • Raising plasma fatty acid concentration induces increased biogenesis of mitochondria in skeletal muscle
    • Garcia-Roves P, Huss JM, Han DH, Hancock CR, Iglesias-Gutierrez E, et al. (2007) Raising plasma fatty acid concentration induces increased biogenesis of mitochondria in skeletal muscle. Proc Natl Acad Sci U S A 104: 10709-13.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 10709-10713
    • Garcia-Roves, P.1    Huss, J.M.2    Han, D.H.3    Hancock, C.R.4    Iglesias-Gutierrez, E.5
  • 36
    • 82155184140 scopus 로고    scopus 로고
    • Fine metabolic regulation in ruminants via nutrient-gene interactions: saturated long-chain fatty acids increase expression of genes involved in lipid metabolism and immune response partly through PPAR-alpha activation
    • Bionaz M, Thering BJ, Loor JJ, (2012) Fine metabolic regulation in ruminants via nutrient-gene interactions: saturated long-chain fatty acids increase expression of genes involved in lipid metabolism and immune response partly through PPAR-alpha activation. Br J Nutr 107: 179-91.
    • (2012) Br J Nutr , vol.107 , pp. 179-191
    • Bionaz, M.1    Thering, B.J.2    Loor, J.J.3
  • 37
    • 80052454265 scopus 로고    scopus 로고
    • ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-alpha and PGC-1
    • Haemmerle G, Moustafa T, Woelkart G, Buttner S, Schmidt A, et al. (2011) ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-alpha and PGC-1. Nat Med 17: 1076-85.
    • (2011) Nat Med , vol.17 , pp. 1076-1085
    • Haemmerle, G.1    Moustafa, T.2    Woelkart, G.3    Buttner, S.4    Schmidt, A.5
  • 38
    • 36649034268 scopus 로고    scopus 로고
    • Dietary supplementation with omega-3 PUFA increases adiponectin and attenuates ventricular remodeling and dysfunction with pressure overload
    • Duda MK, O'Shea KM, Lei B, Barrows BR, Azimzadeh AM, et al. (2007) Dietary supplementation with omega-3 PUFA increases adiponectin and attenuates ventricular remodeling and dysfunction with pressure overload. Cardiovasc Res 76: 303-10.
    • (2007) Cardiovasc Res , vol.76 , pp. 303-310
    • Duda, M.K.1    O'Shea, K.M.2    Lei, B.3    Barrows, B.R.4    Azimzadeh, A.M.5
  • 39
    • 84555186823 scopus 로고    scopus 로고
    • High intake of saturated fat, but not polyunsaturated fat, improves survival in heart failure despite persistent mitochondrial defects
    • Galvao TF, Brown BH, Hecker PA, O'Connell KA, O'Shea KM, et al. (2012) High intake of saturated fat, but not polyunsaturated fat, improves survival in heart failure despite persistent mitochondrial defects. Cardiovasc Res 93: 24-32.
    • (2012) Cardiovasc Res , vol.93 , pp. 24-32
    • Galvao, T.F.1    Brown, B.H.2    Hecker, P.A.3    O'Connell, K.A.4    O'Shea, K.M.5
  • 40
    • 61949464059 scopus 로고    scopus 로고
    • Omega-6 fatty acids and risk for cardiovascular disease: a science advisory from the American Heart Association Nutrition Subcommittee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Cardiovascular Nursing; and Council on Epidemiology and Prevention
    • Harris WS, Mozaffarian D, Rimm E, Kris-Etherton P, Rudel LL, et al. (2009) Omega-6 fatty acids and risk for cardiovascular disease: a science advisory from the American Heart Association Nutrition Subcommittee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Cardiovascular Nursing; and Council on Epidemiology and Prevention. Circulation 119: 902-7.
    • (2009) Circulation , vol.119 , pp. 902-907
    • Harris, W.S.1    Mozaffarian, D.2    Rimm, E.3    Kris-Etherton, P.4    Rudel, L.L.5
  • 41
    • 84857882542 scopus 로고    scopus 로고
    • Dietary fat and heart failure: moving from lipotoxicity to lipoprotection
    • Stanley WC, Dabkowski ER, Ribeiro RF Jr, O'Connell KA, (2012) Dietary fat and heart failure: moving from lipotoxicity to lipoprotection. Circ Res 110: 764-76.
    • (2012) Circ Res , vol.110 , pp. 764-776
    • Stanley, W.C.1    Dabkowski, E.R.2    Ribeiro Jr., R.F.3    O'Connell, K.A.4
  • 42
    • 80054736902 scopus 로고    scopus 로고
    • Resveratrol improves survival, hemodynamics and energetics in a rat model of hypertension leading to heart failure
    • Rimbaud S, Ruiz M, Piquereau J, Mateo P, Fortin D, et al. (2011) Resveratrol improves survival, hemodynamics and energetics in a rat model of hypertension leading to heart failure. PLoS One 6: e26391.
    • (2011) PLoS One , vol.6
    • Rimbaud, S.1    Ruiz, M.2    Piquereau, J.3    Mateo, P.4    Fortin, D.5
  • 43
    • 0026701764 scopus 로고
    • Sex-associated differences in left ventricular function in aortic stenosis of the elderly
    • Carroll JD, Carroll EP, Feldman T, Ward DM, Lang RM, et al. (1992) Sex-associated differences in left ventricular function in aortic stenosis of the elderly. Circulation 86: 1099-107.
    • (1992) Circulation , vol.86 , pp. 1099-1107
    • Carroll, J.D.1    Carroll, E.P.2    Feldman, T.3    Ward, D.M.4    Lang, R.M.5
  • 44
    • 33745197797 scopus 로고    scopus 로고
    • Therapeutic implications of the gender-specific aspects of cardiovascular disease
    • Regitz-Zagrosek V, (2006) Therapeutic implications of the gender-specific aspects of cardiovascular disease. Nat Rev Drug Discov 5: 425-38.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 425-438
    • Regitz-Zagrosek, V.1
  • 45
    • 28144452304 scopus 로고    scopus 로고
    • PGC-1 upregulation via estrogen receptors: a common mechanism of salutary effects of estrogen and flutamide on heart function after trauma-hemorrhage
    • Hsieh YC, Yang S, Choudhry MA, Yu HP, Rue LW 3rd, et al (2005) PGC-1 upregulation via estrogen receptors: a common mechanism of salutary effects of estrogen and flutamide on heart function after trauma-hemorrhage. Am J Physiol Heart Circ Physiol 289: H2665-72.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289
    • Hsieh, Y.C.1    Yang, S.2    Choudhry, M.A.3    Yu, H.P.4    Rue 3rd, L.W.5
  • 46
    • 33746023956 scopus 로고    scopus 로고
    • Inhibition of cardiac PGC-1alpha expression abolishes ERbeta agonist-mediated cardioprotection following trauma-hemorrhage
    • Hsieh YC, Choudhry MA, Yu HP, Shimizu T, Yang S, et al. (2006) Inhibition of cardiac PGC-1alpha expression abolishes ERbeta agonist-mediated cardioprotection following trauma-hemorrhage. FASEB J 20: 1109-17.
    • (2006) FASEB J , vol.20 , pp. 1109-1117
    • Hsieh, Y.C.1    Choudhry, M.A.2    Yu, H.P.3    Shimizu, T.4    Yang, S.5
  • 47
    • 33845991136 scopus 로고    scopus 로고
    • Expression of mitochondrial biogenesis-signaling factors in brown adipocytes is influenced specifically by 17beta-estradiol, testosterone, and progesterone
    • Rodriguez-Cuenca S, Monjo M, Gianotti M, Proenza AM, Roca P, (2007) Expression of mitochondrial biogenesis-signaling factors in brown adipocytes is influenced specifically by 17beta-estradiol, testosterone, and progesterone. Am J Physiol Endocrinol Metab 292: E340-6.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Rodriguez-Cuenca, S.1    Monjo, M.2    Gianotti, M.3    Proenza, A.M.4    Roca, P.5
  • 49
    • 4344575903 scopus 로고    scopus 로고
    • Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease
    • Austin RC, Lentz SR, Werstuck GH, (2004) Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease. Cell Death Differ 11Suppl 1: S56-64.
    • (2004) Cell Death Differ , vol.11
    • Austin, R.C.1    Lentz, S.R.2    Werstuck, G.H.3
  • 50
    • 31544474012 scopus 로고    scopus 로고
    • Effect of an exercise training program on endothelial dysfunction in diabetic and non-diabetic patients with severe chronic heart failure
    • Miche E, Herrmann G, Nowak M, Wirtz U, Tietz M, et al. (2006) Effect of an exercise training program on endothelial dysfunction in diabetic and non-diabetic patients with severe chronic heart failure. Clin Res Cardiol 95Suppl 1: i117-24.
    • (2006) Clin Res Cardiol , vol.95
    • Miche, E.1    Herrmann, G.2    Nowak, M.3    Wirtz, U.4    Tietz, M.5
  • 51
    • 77951667552 scopus 로고    scopus 로고
    • Plasma homocysteine and cardiovascular risk in heart failure with and without cardiorenal syndrome
    • Maurer M, Burri S, de Marchi S, Hullin R, Martinelli M, et al. (2010) Plasma homocysteine and cardiovascular risk in heart failure with and without cardiorenal syndrome. Int J Cardiol 141: 32-8.
    • (2010) Int J Cardiol , vol.141 , pp. 32-38
    • Maurer, M.1    Burri, S.2    de Marchi, S.3    Hullin, R.4    Martinelli, M.5
  • 52
    • 0028017973 scopus 로고
    • Hepatic cobalamin deficiency induced by hydroxycobalamin[c-lactam] treatment in rats is associated with decreased mitochondrial mRNA contents and accumulation of polycistronic mitochondrial RNAs
    • Leeds FS, Brass EP, (1994) Hepatic cobalamin deficiency induced by hydroxycobalamin[c-lactam] treatment in rats is associated with decreased mitochondrial mRNA contents and accumulation of polycistronic mitochondrial RNAs. J Biol Chem 269: 3947-51.
    • (1994) J Biol Chem , vol.269 , pp. 3947-3951
    • Leeds, F.S.1    Brass, E.P.2
  • 53
    • 77049095371 scopus 로고    scopus 로고
    • Synergistic anti-Parkinsonism activity of high doses of B vitamins in a chronic cellular model
    • Jia H, Liu Z, Li X, Feng Z, Hao J, et al. (2010) Synergistic anti-Parkinsonism activity of high doses of B vitamins in a chronic cellular model. Neurobiol Aging 31: 636-46.
    • (2010) Neurobiol Aging , vol.31 , pp. 636-646
    • Jia, H.1    Liu, Z.2    Li, X.3    Feng, Z.4    Hao, J.5
  • 54
    • 80054758185 scopus 로고    scopus 로고
    • Methyl donor deficiency induces cardiomyopathy through altered methylation/acetylation of PGC-1alpha by PRMT1 and SIRT1
    • Garcia MM, Gueant-Rodriguez RM, Pooya S, Brachet P, Alberto JM, et al. (2011) Methyl donor deficiency induces cardiomyopathy through altered methylation/acetylation of PGC-1alpha by PRMT1 and SIRT1. J Pathol 225: 324-335.
    • (2011) J Pathol , vol.225 , pp. 324-335
    • Garcia, M.M.1    Gueant-Rodriguez, R.M.2    Pooya, S.3    Brachet, P.4    Alberto, J.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.