High intake of saturated fat, but not polyunsaturated fat, improves survival in heart failure despite persistent mitochondrial defects

Cardiovascular Research

Volumn 93, Issue 1, 2012, Pages 24-32

  Galvao, Tatiana F ^a,b   Brown, Bethany H ^a   Hecker, Peter A ^a   Oconnell, Kelly A ^a   Oshea, Karen M ^a   Sabbah, Hani N ^c   Rastogi, Sharad ^c   Daneault, Caroline ^d   Des Rosiers, Christine ^d   Stanley, William C ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b HOSPITAL ISRAELITA ALBERT EINSTEIN   (Brazil)

^c HENRY FORD HOSPITAL   (United States)

^d MONTREAL HEART INSTITUTE   (Canada)

Author keywords

Cardiomyopathy; Low carbohydrate diet; Metabolism; Obesity

Indexed keywords

DELTA SARCOGLYCAN; LINOLEIC ACID; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; OXIDOREDUCTASE; PALMITIC ACID; POLYUNSATURATED FATTY ACID; STEARIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; BODY MASS; CONTROLLED STUDY; ENZYME ACTIVITY; HAMSTER; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE MASS; HEART LEFT VENTRICLE SIZE; HEART MITOCHONDRION; HISTOPATHOLOGY; LIPID COMPOSITION; LIPID DIET; LOW FAT DIET; MALE; METABOLIC PARAMETERS; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; SURVIVAL RATE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CARDIOMYOPATHY, DILATED; CRICETINAE; DIET, HIGH-FAT; DIETARY FATS; DIETARY FATS, UNSATURATED; FATTY ACIDS; HEART FAILURE; MALE; MITOCHONDRIA, HEART; PHOSPHOLIPIDS; SARCOGLYCANS;

EID: 84555186823     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvr258     Document Type: Article

References (37)

1. Chess DJ, Stanley WC. Role of diet and fuel overabundance in the development and progression of heart failure. Cardiovasc Res 2008;79:269-278. (Pubitemid 351951607)
2. Lindenfeld J, Albert NM, Boehmer JP, Collins SP, Ezekowitz JA, Givertz MM et al. HFSA 2010 Comprehensive Heart Failure Practice Guideline. J Card Fail 2010;16: e1-e194.
3. Lichtenstein AH, Appel LJ, Brands M, Carnethon M, Daniels S, Franch HA et al. Diet and lifestyle recommendations revision 2006: a scientific statement from the American Heart Association Nutrition Committee. Circulation 2006;114:82-96. (Pubitemid 44305278)
4. Dickstein K, Cohen-Solal A, Filippatos G, McMurray JJ, Ponikowski P, Poole-Wilson PA et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008. Eur Heart J 2008;29:2388-2442.
5. Morgan EE, Rennison JH, Young ME, McElfresh TA, Kung TA, Tserng KY et al. Effects of chronic activation of peroxisome proliferator-activated receptor-alpha or high-fat feeding in a rat infarct model of heart failure. Am J Physiol Heart Circ Physiol 2006;290: H1899-H1904.
6. Rennison JH, McElfresh TA, Okere IC, Vazquez EJ, Patel HV, Foster AB et al. High-fat diet postinfarction enhances mitochondrial function and does not exacerbate left ventricular dysfunction. Am J Physiol Heart Circ Physiol 2007;292:H1498-H1506. (Pubitemid 46377138)
7. Rennison JH, McElfresh TA, Okere IC, Patel HV, Foster AB, Patel KK et al. Enhanced acyl-CoA dehydrogenase activity is associated with improved mitochondrial and contractile function in heart failure. Cardiovasc Res 2008;79:331-340. (Pubitemid 351951606)
8. Rennison JH, McElfresh TA, Chen X, Anand VR, Hoit BD, Hoppel CL et al. Prolonged exposure to high dietary lipids is not associated with lipotoxicity in heart failure. J Mol Cell Cardiol 2009;46:883-890.
9. Chess DJ, Lei B, Hoit BD, Azimzadeh AM, Stanley WC. Effects of a high saturated fat diet on cardiac hypertrophy and dysfunction in response to pressure overload. J Card Fail 2008;14:82-88.
10. Chess DJ, Khairallah RJ, O'Shea KM, Xu W, Stanley WC. A high-fat diet increases adiposity but maintains mitochondrial oxidative enzymes without affecting development of heart failure with pressure overload. Am J Physiol Heart Circ Physiol 2009;297: H1585-H1593.
11. Okere IC, Young ME, McElfresh TA, Chess DJ, Sharov VG, Sabbah HN et al. Low carbohydrate/high-fat diet attenuates cardiac hypertrophy, remodeling, and altered gene expression in hypertension. Hypertension 2006;48:1116-1123. (Pubitemid 44772716)
12. Sharma N, Okere IC, Duda MK, Johnson J, Yuan CL, Chandler MP et al. High fructose diet increases mortality in hypertensive rats compared to a complex carbohydrate or high fat diet. Am J Hypertens 2007;20:403-409. (Pubitemid 46441753)
13. Sharma N, Okere IC, Barrows BR, Lei B, Duda MK, Yuan CL et al. High-sugar diets increase cardiac dysfunction and mortality in hypertension compared to lowcarbohydrate or high-starch diets. J Hypertens 2008;26:1402-1410.
14. Chicco AJ, Sparagna GC, McCune SA, Johnson CA, Murphy RC, Bolden DA et al. Linoleate-rich high-fat diet decreases mortality in hypertensive heart failure rats compared with lard and low-fat diets. Hypertension 2008;52:549-555.
15. Fiaccavento R, Carotenuto F, Minieri M, Masuelli L, Vecchini A, Bei R et al. Alphalinolenic acid-enriched diet prevents myocardial damage and expands longevity in cardiomyopathic hamsters. Am J Pathol 2006;169:1913-1924. (Pubitemid 351181954)
16. Halton TL, Willett WC, Liu S, Manson JE, Albert CM, Rexrode K et al. Low-carbohydrate-diet score and the risk of coronary heart disease in women. N Engl J Med 2006;355:1991-2002. (Pubitemid 44708018)
17. Hu FB. Diet and cardiovascular disease prevention the need for a paradigm shift. J Am Coll Cardiol 2007;50:22-24.
18. Duda MK, O'Shea KM, Lei B, Barrows BR, Azimzadeh AM, McElfresh TE et al. Lowcarbohydrate/high-fat diet attenuates pressure overload-induced ventricular remodeling and dysfunction. J Card Fail 2008;14:327-335. (Pubitemid 351636236)
19. Okere IC, Chandler MP, McElfresh TA, Rennison JH, Sharov V, Sabbah HN et al. Differential effects of saturated and unsaturated fatty acid diets on cardiomyocyte apoptosis, adipose distribution, and serum leptin. Am J Physiol Heart Circ Physiol 2006;291:H38-H44.
20. D'Hahan N, Taouil K, Dassouli A, Morel JE. Long-term therapy with trimetazidine in cardiomyopathic Syrian hamster BIO 14:6. Eur J Pharmacol 1997;328:163-174. (Pubitemid 27263354)
21. Hoppel CL, Tandler B, ParlandW, Turkaly JS, Albers LD. Hamster cardiomyopathy. A defect in oxidative phosphorylation in the cardiac interfibrillar mitochondria. J Biol Chem 1982;257:1540-1548. (Pubitemid 12121666)
22. Shimizu T, Okamoto H, Chiba S, Matsui Y, Sugawara T, Akino M et al. VEGF-mediated angiogenesis is impaired by angiotensin type 1 receptor blockade in cardiomyopathic hamster hearts. Cardiovasc Res 2003;58:203-212. (Pubitemid 36351639)
23. Mattera GG, Lo GP, Loi FM, Vanoli E, Gagnol JP, Borsini F et al. Istaroxime: a new luso-inotropic agent for heart failure. Am J Cardiol 2007;99:33A-40A.
24. Zhu T, Zhou L, Mori S, Wang Z, McTiernan CF, Qiao C et al. Sustained whole-body functional rescue in congestive heart failure and muscular dystrophy hamsters by systemic gene transfer. Circulation 2005;112:2650-2659. (Pubitemid 41532602)
25. Harris WS, Mozaffarian D, Rimm E, Kris-Etherton P, Rudel LL, Appel LJ et al. Omega-6 fatty acids and risk for cardiovascular disease. A science advisory from the American Heart Association Nutrition Subcommittee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Cardiovascular Nursing; and Council on Epidemiology and Prevention. Circulation 2009;119:902-907.
26. Harris WS. Alpha-linolenic acid: a gift from the land? Circulation 2005;111:2872-2874. (Pubitemid 40814178)
27. Khairallah RJ, Sparagna GC, Khanna N, O'Shea KM, Hecker PA, Kristian T et al. Dietary supplementation with docosahexaenoic acid, but not eicosapentaenoic acid, dramatically alters cardiac mitochondrial phospholipid fatty acid composition and prevents permeability transition. Biochim Biophys Acta 2010;1797:1555-1562.
28. 2+-induced permeability transition. J Mol Cell Cardiol 2009;47:819-827.
29. Dabkowski ER, Williamson CL, Hollander JM. Mitochondria-specific transgenic overexpression of phospholipid hydroperoxide glutathione peroxidase (GPx4) attenuates ischemia/reperfusion-associated cardiac dysfunction. Free Radic Biol Med 2008;45: 855-865.
30. Gelinas R, Thompson-Legault J, Bouchard B, Daneault C, Mansour A, Gillis MA et al. Prolonged QT interval and lipid alterations beyond {beta}-oxidation in very longchain acyl-CoA dehydrogenase null mouse hearts. Am J Physiol Heart Circ Physiol 2011;301:H813-H823.
31. Lionetti V, Stanley WC, Recchia FA. Modulating fatty acid oxidation in heart failure. Cardiovasc Res 2011;90:202-209.
32. Sharov VG, Todor AV, Imai M, Sabbah HN. Inhibition of mitochondrial permeability transition pores by cyclosporine A improves cytochrome C oxidase function and increases rate of ATP synthesis in failing cardiomyocytes. Heart Fail Rev 2005;10: 305-310.
33. Javadov S, Huang C, Kirshenbaum L, Karmazyn M. NHE-1 inhibition improves impaired mitochondrial permeability transition and respiratory function during postinfarction remodelling in the rat. J Mol Cell Cardiol 2005;38:135-143. (Pubitemid 40038660)
34. Oliver MF, Kurien VA, Greenwood TW. Relation between serum-free-fatty acids and arrhythmias and death after acute myocardial infarction. Lancet 1968;1:710-714.
35. Jouven X, Charles MA, Desnos M, Ducimetiere P. Circulating nonesterified fatty acid level as a predictive risk factor for sudden death in the population. Circulation 2001; 104:756-761. (Pubitemid 32762671)
36. Corr PB, Yamada KA. Selected metabolic alterations in the ischemic heart and their contributions to arrhythmogenesis. Herz 1995;20:156-168.
37. Harris WS, Sands SA, Windsor SL, Ali HA, Stevens TL, Magalski A et al. Omega-3 fatty acids in cardiac biopsies from heart transplantation patients: correlation with erythrocytes and response to supplementation. Circulation 2004;110:1645-1649. (Pubitemid 39297988)