Secondary sphere formation enhances the functionality of cardiac progenitor cells

Molecular Therapy

Volumn 20, Issue 9, 2012, Pages 1750-1766

  Cho, Hyun Jai ^a,b   Lee, Ho Jae ^a,b   Youn, Seock Won ^b   Koh, Seok Jin ^b   Won, Joo Yun ^b   Chung, Yeon Ju ^a   Cho, Hyun Ju ^b   Yoon, Chang Hwan ^a   Lee, Sae Won ^b   Lee, Eun Ju ^b   Kwon, Yoo Wook ^b   Lee, Hae Young ^a   Lee, Sang Hun ^c   Ho, Won Kyung ^c   Park, Young Bae ^a,b   Kim, Hyo Soo ^a,b  

^a Seoul National University   (South Korea)

^b Seoul National University Hospital   (South Korea)

^c Seoul National University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SP1; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; HEART MUSCLE CELL; MALE; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; OUTCOME ASSESSMENT; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN SYNTHESIS; STEM CELL; STEM CELL TRANSPLANTATION;

EID: 84867040569     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2012.109     Document Type: Article

References (50)

1. Chavakis, E, Koyanagi, M and Dimmeler, S (2010). Enhancing the outcome of cell therapy for cardiac repair: progress from bench to bedside and back. Circulation 121: 325-335.
2. Murry, CE, Reinecke, H and Pabon, LM (2006). Regeneration gaps: observations on stem cells and cardiac repair. J Am Coll Cardiol 47: 1777-1785.
3. Reinecke, H, Minami, E, Zhu, WZ and Lafamme, MA (2008). Cardiogenic differentiation and transdifferentiation of progenitor cells. Circ Res 103: 1058-1071.
4. Lipinski, MJ, Biondi-Zoccai, GG, Abbate, A, Khianey, R, Sheiban, I, Bartunek, J et al. (2007). Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a collaborative systematic review and meta-analysis of controlled clinical trials. J Am Coll Cardiol 50: 1761-1767. (Pubitemid 47600592)
5. Abdel-Latif, A, Bolli, R, Tleyjeh, IM, Montori, VM, Perin, EC, Hornung, CA et al. (2007). Adult bone marrow-derived cells for cardiac repair: a systematic review and meta-analysis. Arch Intern Med 167: 989-997. (Pubitemid 46835786)
6. Kajstura, J, Urbanek, K, Perl, S, Hosoda, T, Zheng, H, Ogórek, B et al. (2010). Cardiomyogenesis in the adult human heart. Circ Res 107: 305-315.
7. Lafamme, MA and Murry, CE (2011). Heart regeneration. Nature 473: 326-335.
8. Beltrami, A P, Barlucchi, L, Torella, D, Baker, M, Limana, F, Chimenti, S et al. (2003). Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 114: 763-776. (Pubitemid 37186770)
9. Oh, H, Bradfute, SB, Gallardo, TD, Nakamura, T, Gaussin, V, Mishina, Y et al. (2003). Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction. Proc Natl Acad Sci USA 100: 12313-12318. (Pubitemid 37271557)
10. Messina, E, De Angelis, L, Frati, G, Morrone, S, Chimenti, S, Fiordaliso, F et al. (2004). Isolation and expansion of adult cardiac stem cells from human and murine heart. Circ Res 95: 911-921. (Pubitemid 39435006)
11. Pfster, O, Mouquet, F, Jain, M, Summer, R, Helmes, M, Fine, A et al. (2005). CD31-but Not CD31+ cardiac side population cells exhibit functional cardiomyogenic differentiation. Circ Res 97: 52-61. (Pubitemid 40982322)
12. Smits, AM, van Laake, LW, den Ouden, K, Schreurs, C, Szuhai, K, van Echteld, CJ et al. (2009). Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardium. Cardiovasc Res 83: 527-535.
13. Leri, A, Kajstura, J and Anversa, P (2011). Role of cardiac stem cells in cardiac pathophysiology: a paradigm shift in human myocardial biology. Circ Res 109: 941-961.
14. Smith, RR, Barile, L, Cho, HC, Leppo, MK, Hare, JM, Messina, E et al. (2007). Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens. Circulation 115: 896-908. (Pubitemid 46294730)
15. Davis, DR, Zhang, Y, Smith, RR, Cheng, K, Terrovitis, J, Malliaras, K et al. (2009). Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue. PLoS ONE 4: e7195.
16. Li, TS, Cheng, K, Lee, ST, Matsushita, S, Davis, D, Malliaras, K et al. (2010). Cardiospheres recapitulate a niche-like microenvironment rich in stemness and cellmatrix interactions, rationalizing their enhanced functional potency for myocardial repair. Stem Cells 28: 2088-2098.
17. Davis, DR, Kizana, E, Terrovitis, J, Barth, AS, Zhang, Y, Smith, RR et al. (2010). Isolation and expansion of functionally-competent cardiac progenitor cells directly from heart biopsies. J Mol Cell Cardiol 49: 312-321.
18. Terrovitis, J, Lautamäki, R, Bonios, M, Fox, J, Engles, JM, Yu, J et al. (2009). Noninvasive quantifcation and optimization of acute cell retention by in vivo positron emission tomography after intramyocardial cardiac-derived stem cell delivery. J Am Coll Cardiol 54: 1619-1626.
19. Terrovitis, JV, Smith, RR and Marbán, E (2010). Assessment and optimization of cell engraftment after transplantation into the heart. Circ Res 106: 479-494.
20. Cho, HJ, Lee, N, Lee, JY, Choi, YJ, Ii, M, Wecker, A et al. (2007). Role of host tissues for sustained humoral effects after endothelial progenitor cell transplantation into the ischemic heart. J Exp Med 204: 3257-3269.
21. Li, Z, Lee, A, Huang, M, Chun, H, Chung, J, Chu, P et al. (2009). Imaging survival and function of transplanted cardiac resident stem cells. J Am Coll Cardiol 53: 1229-1240.
22. Lafamme, MA, Chen, KY, Naumova, AV, Muskheli, V, Fugate, JA, Dupras, SK et al. (2007). Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol 25: 1015-1024. (Pubitemid 47517637)
23. Shenje, LT, Field, LJ, Pritchard, CA, Guerin, CJ, Rubart, M, Soonpaa, MH et al. (2008). Lineage tracing of cardiac explant derived cells. PLoS ONE 3: e1929.
24. Andersen, DC, Andersen, P, Schneider, M, Jensen, HB and Sheikh, SP (2009). Murine "cardiospheres" are not a source of stem cells with cardiomyogenic potential. Stem Cells 27: 1571-1581.
25. Dani, C, Smith, AG, Dessolin, S, Leroy, P, Staccini, L, Villageois, P et al. (1997). Differentiation of embryonic stem cells into adipocytes in vitro. J Cell Sci 110 (Pt 11): 1279-1285. (Pubitemid 27273698)
26. Yoon, CH, Koyanagi, M, Iekushi, K, Seeger, F, Urbich, C, Zeiher, AM et al. (2010). Mechanism of improved cardiac function after bone marrow mononuclear cell therapy: role of cardiovascular lineage commitment. Circulation 121: 2001-2011.
27. Chang, SA, Lee, EJ, Kang, HJ, Zhang, SY, Kim, JH, Li, L et al. (2008). Impact of myocardial infarct proteins and oscillating pressure on the differentiation of mesenchymal stem cells: effect of acute myocardial infarction on stem cell differentiation. Stem Cells 26: 1901-1912.
28. Dang, SM, Kyba, M, Perlingeiro, R, Daley, GQ and Zandstra, PW (2002). Effciency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems. Biotechnol Bioeng 78: 442-453. (Pubitemid 34712364)
29. Ziebart, T, Yoon, CH, Trepels, T, Wietelmann, A, Braun, T, Kiessling, F et al. (2008). Sustained persistence of transplanted proangiogenic cells contributes to neovascularization and cardiac function after ischemia. Circ Res 103: 1327-1334.
30. Lee, DW, Lee, TK, Cho, IS, Park, HE, Jin, S, Cho, HJ et al. (2011). Creation of myocardial fbrosis by transplantation of fbroblasts primed with survival factors. Am J Physiol Heart Circ Physiol 301: H1004-H1014.
31. van Laake, LW, Passier, R, Monshouwer-Kloots, J, Verkleij, AJ, Lips, DJ, Freund, C et al. (2007). Human embryonic stem cell-derived cardiomyocytes survive and mature in the mouse heart and transiently improve function after myocardial infarction. Stem Cell Res 1: 9-24. (Pubitemid 350251944)
32. Gnecchi, M, Zhang, Z, Ni, A and Dzau, VJ (2008). Paracrine mechanisms in adult stem cell signaling and therapy. Circ Res 103: 1204-1219.
33. Peerani, R and Zandstra, PW (2010). Enabling stem cell therapies through synthetic stem cell-niche engineering. J Clin Invest 120: 60-70.
34. Oh, IY, Yoon, CH, Hur, J, Kim, JH, Kim, TY, Lee, CS et al. (2007). Involvement of E-selectin in recruitment of endothelial progenitor cells and angiogenesis in ischemic muscle. Blood 110: 3891-3899. (Pubitemid 350248444)
35. Campos, LS, Leone, DP, Relvas, JB, Brakebusch, C, Fässler, R, Suter, U et al. (2004). Beta1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance. Development 131: 3433-3444. (Pubitemid 39139889)
36. Ishii, S, Okada, Y, Kadoya, T, Matsuzaki, Y, Shimazaki, T and Okano, H (2010). Stromal cell-secreted factors promote the survival of embryonic stem cell-derived early neural stem/progenitor cells via the activation of MAPK and PI3K-Akt pathways. J Neurosci Res 88: 722-734.
37. Curry, JM, Eubank, TD, Roberts, RD, Wang, Y, Pore, N, Maity, A et al. (2008). M-CSF signals through the MAPK/ERK pathway via Sp1 to induce VEGF production and induces angiogenesis in vivo. PLoS ONE 3: e3405.
38. Ryuto, M, Ono, M, Izumi, H, Yoshida, S, Weich, HA, Kohno, K et al. (1996). Induction of vascular endothelial growth factor by tumor necrosis factor alpha in human glioma cells. Possible roles of SP-1. J Biol Chem 271: 28220-28228. (Pubitemid 26374633)
39. Galli, R, Gritti, A, Bonfanti, L and Vescovi, AL (2003). Neural stem cells: an overview. Circ Res 92: 598-608. (Pubitemid 36417693)
40. Rietze, RL, Valcanis, H, Brooker, GF, Thomas, T, Voss, AK and Bartlett, PF (2001). Purifcation of a pluripotent neural stem cell from the adult mouse brain. Nature 412: 736-739. (Pubitemid 32771996)
41. Ma, BF, Liu, XM, Xie, XM, Zhang, AX, Zhang, JQ, Yu, WH et al. (2006). Slower cycling of nestin-positive cells in neurosphere culture. Neuroreport 17: 377-381.
42. Hattori, F, Chen, H, Yamashita, H, Tohyama, S, Satoh, YS, Yuasa, S et al. (2010). Nongenetic method for purifying stem cell-derived cardiomyocytes. Nat Methods 7: 61-66.
43. Chimenti, I, Smith, RR, Li, TS, Gerstenblith, G, Messina, E, Giacomello, A et al. (2010). Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice. Circ Res 106: 971-980.
44. Yoon, CH, Hur, J, Park, KW, Kim, JH, Lee, CS, Oh, IY et al. (2005). Synergistic neovascularization by mixed transplantation of early endothelial progenitor cells and late outgrowth endothelial cells: the role of angiogenic cytokines and matrix metalloproteinases. Circulation 112: 1618-1627. (Pubitemid 41324524)
45. Cho, HJ, Youn, SW, Cheon, SI, Kim, TY, Hur, J, Zhang, SY et al. (2005). Regulation of endothelial cell and endothelial progenitor cell survival and vasculogenesis by integrin-linked kinase. Arterioscler Thromb Vasc Biol 25: 1154-1160. (Pubitemid 40776602)
46. Favata, MF, Horiuchi, KY, Manos, EJ, Daulerio, AJ, Stradley, DA, Feeser, WS et al. (1998). Identifcation of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 273: 18623-18632. (Pubitemid 28334795)
47. Vlahos, CJ, Matter, WF, Hui, KY and Brown, RF (1994). A specifc inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4- one (LY294002). J Biol Chem 269: 5241-5248.
48. Koyanagi, M, Iwasaki, M, Rupp, S, Tedesco, FS, Yoon, CH, Boeckel, JN et al. (2010). Sox2 transduction enhances cardiovascular repair capacity of blood-derived mesoangioblasts. Circ Res 106: 1290-1302.
49. Scherr, M, Battmer, K, Blömer, U, Schiedlmeier, B, Ganser, A, Grez, M et al. (2002). Lentiviral gene transfer into peripheral blood-derived CD34+ NOD/SCID-repopulating cells. Blood 99: 709-712. (Pubitemid 34533114)
50. Hahn, JY, Cho, HJ, Bae, JW, Yuk, HS, Kim, KI, Park, KW et al. (2006). Beta-catenin overexpression reduces myocardial infarct size through differential effects on cardiomyocytes and cardiac fbroblasts. J Biol Chem 281: 30979-30989.