The orphan receptor GPR3 modulates the early phases of cocaine reinforcement

British Journal of Pharmacology

Volumn 167, Issue 4, 2012, Pages 892-904

  Tourino, Clara ^a   Valjent, Emmanuel ^b,d   Ruiz Medina, Jessica ^a   Herve, Denis ^b   Ledent, Catherine ^c   Valverde, Olga ^a  

^a UNIVERSITAT POMPEU FABRA   (Spain)

^b INSERM   (France)

^c UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^d UNIV MONTPELLIER   (France)

Author keywords

adenylyl cyclase; cocaine; Gpr3 receptor deficient mice; intravenous self administration; orphan receptor; reinforcement

Indexed keywords

DOPAMINE; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COCAINE DEPENDENCE; CONTROLLED STUDY; DOPAMINE RELEASE; DRUG SEEKING BEHAVIOR; EXTRACELLULAR SPACE; FEMALE; GENE DELETION; GENOTYPE; INSTRUMENTAL CONDITIONING; LOCOMOTION; MALE; MOUSE; NEUROMODULATION; NEUROPATHOLOGY; NONHUMAN; NUCLEUS ACCUMBENS; PLACE PREFERENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; REINFORCEMENT; REWARD; SENSITIZATION; SIGNAL TRANSDUCTION;

ANIMALS; BEHAVIOR, ANIMAL; COCAINE; CONDITIONING, OPERANT; DOPAMINE; FOOD; MALE; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; NUCLEUS ACCUMBENS; RECEPTORS, G-PROTEIN-COUPLED; REINFORCEMENT (PSYCHOLOGY); SELF ADMINISTRATION;

EID: 84867012812     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.02043.x     Document Type: Article

References (41)

1. Alexander SPH, Mathie A, Peters JA, (2011). Guide to Receptors and Channels (GRAC), 5th Edition. Br J Pharmacol 164 (Suppl. 1): S1-S324.
2. Antelman SM, Eichler AJ, Black CA, Kocan D, (1980). Interchangeability of stress and amphetamine in sensitization. Science 207: 329-331.
3. Aso E, Renoir T, Mengod G, Ledent C, Hamon M, Maldonado R, et al,. (2009). Lack of CB1 receptor activity impairs serotonergic negative feedback. J Neurochem 109: 935-944.
4. Bari AA, Pierce RC, (2005). D1-like and D2 dopamine receptor antagonists administered into the shell subregion of the rat nucleus accumbens decrease cocaine, but not food, reinforcement. Neuroscience 135: 959-968.
5. Chuhma N, Zhang H, Masson J, Zhuang X, Sulzer D, Hen R, et al,. (2004). Dopamine neurons mediate a fast excitatory signal via their glutamatergic synapses. J Neurosci 24: 972-981.
6. Corvol JC, Valjent E, Pascoli V, Robin A, Stipanovich A, Luedtke RR, et al,. (2007). Quantitative changes in Galphaolf protein levels, but not D1 receptor, alter specifically acute responses to psychostimulants. Neuropsychopharmacology 32: 1109-1121.
7. DiChiara G, Acquas E, Carboni E, (1992). Drugs motivation and addiction: a neurobiological perspective. Ann N Y Acad Sci 654: 207-219.
8. DiRocco DP, Scheiner ZS, Sindreu CB, Chan GC, Storm DR, (2009). A role for calmoduli-stimulated adenylyl cyclase in cocaine sensitization. J Neurosci 29: 2393-2403.
9. Edwards S, Graham DL, Bachtell RK, Self DW, (2007). Region-specific tolerance to cocaine-regulated cAMP-dependent protein phosphorylation following chronic self-administration. Eur J Neurosci 25: 2201-2213.
10. Eggerickx D, Denef JF, Labbe O, Hayashi Y, Refetoff S, Vassart G, et al,. (1995). Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylyl cyclase. Biochem J 309: 837-843.
11. Everitt BJ, Robbins TW, (2005). Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nat Neurosci 8: 1481-1489.
12. Freudzon L, Norris RP, Hand AR, Tanaka S, Saeki Y, Jones TL, et al,. (2005). Regulation of meiotic prophase arrest in mouse oocytes by GPR3, a constitutive activator of the Gs G protein. J Cell Biol 171: 255-265.
13. Green TA, Alibhai IN, Hommel JD, DiLeone RJ, Kumar A, Theobald DE, et al,. (2006). Induction of inducible cAMP early repressor expression in nucleus accumbens by stress or amphetamine increases behavioral responses to emotional stimuli. J Neurosci 26: 8235-8242.
14. Hinckley M, Vaccari S, Horner K, Chen R, Conti M, (2005). The G-protein-coupled receptors GPR3 and GPR12 are involved in cAMP signaling and maintenance of meiotic arrest in rodent oocytes. Dev Biol 287: 249-261.
15. Hnasko TS, Sotak BN, Palmiter RD, (2007). Cocaine-conditioned place preference by dopamine-deficient mice is mediated by serotonin. J Neurosci 27: 12484-12488.
16. Hyman SE, Malenka RC, Nestler EJ, (2006). Neural mechanisms of addiction: the role of reward-related learning and memory. Annu Rev Neurosci 29: 565-598.
17. Jaber M, Robinson S, Missale C, Caron MG, (1996). Dopamine receptors and brain function. Neuropharmacology 35: 1503-1519.
18. Joost P, Methner A, (2002). Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands. Genome Biol 3: RESEARCH0063.
19. Kaddis FG, Wallace LJ, Uretsky NJ, (1993). AMPA/kainate antagonists in the nucleus accumbens inhibit locomotor stimulatory response to cocaine and dopamine agonists. Pharmacol Biochem Behav 46: 703-708.
20. Kiyatkin EA, Rebec GV, (2000). Dopamine-independent action of cocaine on striatal and accumbal neurons. Eur J Neurosci 12: 1789-1800.
21. Kostenis E, (2004). Novel clusters of receptors for sphingosine-1- phosphate, sphingosylphosphorylcholine, and (lyso)-phosphatidic acid: new receptors for 'old' ligands. J Cell Biochem 92: 923-936.
22. Ledent C, Demeestere I, Blum D, Petermans J, Hamalainen T, Smits G, et al,. (2005). Premature ovarian aging in mice deficient for Gpr3. Proc Natl Acad Sci U S A 102: 8922-8926.
23. Martin M, Ledent C, Parmentier M, Maldonado R, Valverde O, (2000). Cocaine, but not morphine, induces conditioned place preference and sensitization to locomotor responses in CB1 knockout mice. Eur J Neurosci 12: 4038-4046.
24. McGrath J, Drummond G, McLachlan E, Kilkenny C, Wainwright C, (2010). Guidelines for reporting experiments involving animals: the ARRIVE guidelines. Br J Pharmacol 160: 1573-1576.
25. Mehlmann LM, Saeki Y, Tanaka S, Brennan TJ, Evsikov AV, Pendola FL, et al,. (2004). The Gs-linked receptor GPR3 maintains meiotic arrest in mammalian oocytes. Science 306: 1947-1950.
26. Miserendino MJ, Nestler EJ, (1995). Behavioral sensitization to cocaine: modulation by the cyclic AMP system in the nucleus accumbens. Brain Res 674: 299-306.
27. Nestler EJ, (2005). Is there a common molecular pathway for addiction? Nat Neurosci 8: 1445-1449.
28. Nijenhuis WA, Oosterom J, Adan RA, (2001). AgRP(83-132) acts as an inverse agonist on the human-melanocortin-4 receptor. Mol Endocrinol 15: 164-171.
29. Rocha BA, Fumagalli F, Gainetdinov RR, Jones SR, Ator R, Giros B, et al,. (1998). Cocaine self-administration in dopamine-transporter knockout mice. Nat Neurosci 1: 132-137.
30. Rothman RB, Baumann MH, (2003). Monoamine transporters and psychostimulant drugs. Eur J Pharmacol 479: 23-40.
31. Roux S, Froger C, Porsolt RD, Valverde O, Maldonado R, (2003). Place preference test in rodents. Curr Protoc Neurosci Chapter 9: Unit 9.15.
32. Saeki Y, Ueno S, Mizuno R, Nishimura T, Fujimura H, Nagai Y, et al,. (1993). Molecular cloning of a novel putative G protein-coupled receptor (GPCR21) which is expressed predominantly in mouse central nervous system. FEBS Lett 336: 317-322.
33. Sora I, Wichems C, Takahashi N, Li XF, Zeng Z, Revay R, et al,. (1998). Cocaine reward models: conditioned place preference can be established in dopamine- and serotonin-transporter knockout mice. Proc Natl Acad Sci USA 95: 7699-76704.
34. Sora I, Hall FS, Andrews AM, Itokawa M, Li XF, Wei HB, et al,. (2001). Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proc Natl Acad Sci USA 98: 5300-5305.
35. Sora I, Li B, Igari M, Hall FS, Ikeda K, (2010). Transgenic mice in the study of drug addiction and the effects of psychostimulant drugs. Ann N Y Acad Sci 1187: 218-246.
36. Soria G, Mendizábal V, Touriño C, Robledo P, Ledent C, Parmentier M, et al,. (2005). Lack of CB1 cannabinoid receptor impairs cocaine self-administration. Neuropsychopharmacology 30: 1670-1680.
37. Tanaka S, Ishii K, Kasai K, Yoon SO, Yoshinaga Saeki Y, (2009). Neural expression of G protein-coupled receptors GPR3, GPR6, and GPR12 Up-regulates cyclic AMP levels and promotes neurite outgrowth. J Biol Chem 282: 10506-10515.
38. Thathiah A, Spittaels K, Hoffmann M, Staes M, Cohen A, Horre K, et al,. (2009). The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons. Science 323: 946-951.
39. Touriño C, Ledent C, Maldonado R, Valverde O, (2008). CB1 cannabinoid receptor modulates 3,4-methylenedioxymethamphetamine acute responses and reinforcement. Biol Psychiatry 63: 1030-1038.
40. Uhlenbrock K, Gassenhuber H, Kostenis E, (2002). Sphingosine 1-phosphate is a ligand of the human gpr3, gpr6 and gpr12 family of constitutively active G protein-coupled receptors. Cell Signal 14: 941-953.
41. Valverde O, Celerier E, Baranyi M, Vanderhaeghen P, Maldonado R, Sperlagh B, et al,. (2009). GPR3 receptor, a novel actor in the emotional-like responses. PLoS ONE 4: e4704.