Hemoglobin status associated with performance IQ but not verbal IQ in Chinese preschool children

Pediatrics International

Volumn 54, Issue 5, 2012, Pages 669-675

  Ai, Yuexian ^a   Zhao, Sophie R ^b   Zhou, Guoping ^a   Ma, Xiaoyang ^b   Liu, Jianghong ^b  

^a Jintan People's Hospital   (China)

^b UNIVERSITY OF PENNSYLVANIA SCHOOL OF NURSING   (United States)

Author keywords

Chinese children; cognition; hemoglobin; iron; performance IQ; verbal IQ

Indexed keywords

HEMOGLOBIN; IRON;

ANEMIA; ARTICLE; CHILD; CHINA; COGNITION; COGNITIVE DEVELOPMENT; COHORT ANALYSIS; DEVELOPING COUNTRY; FEMALE; HEMOGLOBIN BLOOD LEVEL; HUMAN; INTELLIGENCE QUOTIENT; IRON BLOOD LEVEL; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; PERFORMANCE; PRESCHOOL CHILD; PRIORITY JOURNAL; VERBAL COMMUNICATION; WECHSLER INTELLIGENCE SCALE;

ANEMIA; ASIAN CONTINENTAL ANCESTRY GROUP; CHILD; CHILD, PRESCHOOL; CHINA; COGNITION; COGNITION DISORDERS; COHORT STUDIES; FEMALE; HEMOGLOBINS; HUMANS; INTELLIGENCE; INTELLIGENCE TESTS; IRON; LONGITUDINAL STUDIES; MALE; QUESTIONNAIRES;

EID: 84866996054     PISSN: 13288067     EISSN: 1442200X     Source Type: Journal    
DOI: 10.1111/j.1442-200X.2012.03648.x     Document Type: Article

References (53)

1. Mason J, Bailes A, Beda-Andourou M, et al,. Recent trends in malnutrition in developing regions: vitamin A deficiency, anemia, iodine deficiency, and child underweight. Food Nutr. Bull. 2005; 26: 59-108.
2. World Health Organization. Iron deficiency anemia: assessment, prevention, and control. A Guide for Programme Managers. Geneva, Switzerland, 2001.
3. World Health Organization. Worldwide Prevalence of Anaemia 1993-2005. World Health Organization, Geneva, 2008; 48.
4. Castelnau PA, Garrett RS, Palinski W, Witztum JL, Campbell IL, Powell HC,. Abnormal iron deposition associated with lipid peroxidation in transgenic mice expressing interleukin-6 in the brain. J. Neuropathol. Exp. Neurol. 1998; 572: 268-82.
5. Andorn AC, Britton RS, Bacon BR,. Ascorbate-stimulated lipid peroxidation in human brain is dependent on iron but not on hydroxyl radical. J. Neurochem. 1996; 67: 717-22.
6. Sobotka TJ, Whittaker P, Sobotka JM, et al,. Neurobehavioral dysfunctions associated with dietary iron overload. Physiol. Behav. 1996; 59: 213-19.
7. Centers for Disease Control. Recommendations to prevent and control iron deficiency in the United States. MMWR Morb. Mortal. Wkly Rep. 1998; 47: 1-29.
8. Grantham-McGregor S, Ani C,. A review of studies on the effect of iron deficiency on cognitive development in children. J. Nutr. 2001; 131: 649s-66s.
9. Lozoff B, Corapci F, Burden MJ, et al,. Preschool-aged children with iron deficiency anemia show altered affect and behavior. J. Nutr. 2007; 137: 683-9.
10. Lozoff B, Beard J, Connor J, Felt B, Georgieff M, Schallert T,. Long-lasting neural and behavioral effects of iron deficiency in infancy. Nutr. Rev. 2006; 64: S34-S43.
11. Lozoff B, Jimenez E, Hagen J, Mollen E, Wolf AW,. Poorer behavioral and developmental outcome more than 10 years after treatment for iron deficiency in infancy. Pediatrics 2000; 105: E51.
12. Jorgenson LA, Wobken JD, Georgieff MK,. Perinatal iron deficiency alters apical dendritic growth in hippocampal CA1 pyramidal neurons. Dev. Neurosci. 2003; 25: 412-20.
13. Rao R, Tkac I, Townsend EL, Gruetter R, Georgieff MK,. Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus. J. Nutr. 2003; 133: 3215-21.
14. Youdim M,. Brain iron deficiency and excess; cognitive impairment and neurodegeneration with involvement of striatum and hippocampus. Neurotox. Res. 2008; 14: 45-56.
15. Lozoff B, Brittenham GM, Wolf AW, et al,. Iron deficiency anemia and iron therapy effects on infant developmental test performance. Pediatrics 1987; 79: 981-95.
16. Soewondo S, Husaini M, Pollitt E,. Effects of iron deficiency on attention and learning processes in preschool children: Bandung, Indonesia. Am. J. Clin. Nutr. 1989; 50: 667-73. Discussion 73-4.
17. Nelson M,. Anaemia in adolescent girls: effects on cognitive function and activity. Proc. Nutr. Soc. 1996; 55: 359-67.
18. Khedr E, Hamed SA, Elbeih E, El-Shereef H, Ahmad Y, Ahmed S,. Iron states and cognitive abilities in young adults: neuropsychological and neurophysiological assessment. Eur. Arch. Psychiatry Clin. Neurosci. 2008; 258: 489-96.
19. Chang SY, Wang L, Wang YY, et al,. Iron-deficiency anemia in infancy and social emotional development in preschool-aged Chinese children. Pediatrics 2011; 127: E927-E33.
20. Liu J, McCauley LA, Zhao Y, Zhang H, Pinto-Martin J,. Cohort profile: the China Jintan child cohort study. Int. J. Epidemiol. 2010; 39: 668-74.
21. Wintrobe MM, Lee GR, Boggs DR,. Clinical Hematology, 8th edn. Lea & Febiger, Philadelphia, 1981.
22. Dong S, Zhu Z, Liu W,. Determination of Ca, Mg, Fe, Mn, Cu, and Zn in lixin pill by atomic absorption spectrophotometry. Guang Pu Xue Yu Guang Pu Fen Xi 2001; 21: 391-2.
23. Liu J, Hanlon A, Shi Z, Dickerman B, Compher C,. Micronutrients deficiency and associated sociodemographic factors in Chinese children. World J. Pediatr. 2011; 7: 217-23.
24. Wechsler D,. Wechsler Preschool and Primary Scale of Intelligence. The Psychological Corporation, San Antonio, TX, 1967.
25. Gong YX, Dai XY,. China-Wechsler Young Children Scale of Intelligence (C-WYCSI). Map Press, Hunan, 1992.
26. Gong YX, Dai XY,. China-Wechsler Younger Children Scale of Intelligence. Acta Psychol. Sin. 1988; 20: 364-76.
27. Yang LL, Liu ML, Townes BD,. Neuropsychological and behavioral status of Chinese children with acyanotic congenital heart disease. Int. J. Neurosci. 1994; 74: 109-15.
28. Zhu YM, Lu SY, Tang CH,. [The employment of the Wechsler Pre-school and Primary Scale of Intelligence in urban Shanghai]. Inf. Psychol. Sci. 1984; 5: 22-9 (in Chinese).
29. Bracken BA,. Limitations of preschool instruments and standards for minimal levels of technical adequacy. J. Psychoeduc Assess. 1987; 5: 313-26.
30. DeThorne LS, Schaefer BA,. A guide to currently-used child nonverbal IQ measures. Am. J. Speech Lang. Pathol. 2004; 13: 275-90.
31. Gyurke JS, Marmor DS, Melrose SE,. The assessment of preschool children with the Wechsler preschool and primary scale of intelligence-revised. In:, Bracken ABB, (ed). The Psychoeducational Assessment of Preschool Children, 3rd edn. Allyn & Bacon, Needham Heights, MA, 2000; 57-75.
32. Petranovic D, Batinac T, Ruzic A, Ruzic T,. Iron deficiency anaemia influences cognitive functions. Med. Hypotheses 2008; 70: 70-2.
33. Stoltzfus RJ, Mullany L, Black RE,. Iron deficiency anaemia. In:, Ezzati M, Lopez AD, Rodgers A, Murray CJL, (eds). Comparative Quantification of Health Risks: Global and Regional Burden of Disease Attributable to Selected Major Risk Factors, Vol. 1. World Health Organization, Gevena, 2004; 163-209.
34. Lozoff B, Jimenez E, Wolf AW,. Long-term developmental outcome of infants with iron deficiency. N. Engl. J. Med. 1991; 325: 687-94.
35. Hurtado EK, Claussen AH, Scott KG,. Early childhood anemia and mild or moderate mental retardation. Am. J. Clin. Nutr. 1999; 69: 115-19.
36. de Andraca I, Walter T, Castillo M, Pino P, Rivera P, Cobo C,. Iron Deficiency Anemia and Its Effects upon Psychological Development at Pre-School Age: A Logitudinal Study. Nestle Foundation, Lausanne, 1990.
37. McCartney K,. Effect of quality of day care environment on children's language development. Dev. Psychol. 1984; 20: 244-60.
38. Barbarin O, Bryant D, McCandies T, et al,. Children enrolled in public pre-K: the relation of family life, neighborhood quality, and socioeconomic resources to early competence. Am. J. Orthopsychiatry 2006; 76: 265-76.
39. Dunn L, Beach SA, Kontos S,. Quality of the literacy environment in day care and children's development. J. Res. Child. Educ. 1994; 9: 24-34.
40. Sungthong R, Mo-Suwan L, Chongsuvivatwong V,. Effects of haemoglobin and serum ferritin on cognitive function in school children. Asia Pac. J. Clin. Nutr. 2002; 11: 117-22.
41. Tamura T, Goldenberg RL, Hou JR, et al,. Cord serum ferritin concentrations and mental and psychomotor development of children at five years of age. J. Pediatr. 2002; 140: 165-70.
42. Galler JR, Ramsey FC, Morley DS, Archer E, Salt P,. The long-term effects of early kwashiorkor compared with marasmus.4. performance on the national high-school entrance examination. Pediatr. Res. 1990; 28: 235-39.
43. Bennis-Taleb N, Remacle C, Hoet JJ, Reusens B,. A low-protein isocaloric diet during gestation affects brain development and alters permanently cerebral cortex blood vessels in rat offspring. J. Nutr. 1999; 129: 1613-19.
44. Liu J, Raine A, Venables PH, Dalais C, Mednick SA,. Malnutrition at age 3 years and lower cognitive ability at age 11 years: independence from psychosocial adversity. Arch. Pediatr. Adolesc. Med. 2003; 157: 593-600.
45. Morgane PJ, Austin-LaFrance R, Bronzino J, et al,. Prenatal malnutrition and development of the brain. Neurosci. Biobehav. Rev. 1993; 17: 91-128.
46. Morgane PJ, Mokler DJ, Galler JR,. Effects of prenatal protein malnutrition on the hippocampal formation. Neurosci. Biobehav. Rev. 2002; 26: 471-83.
47. Piñero DJ, Jones BC, Beard JL,. Variations in dietary iron alter behavior in developing rats. J. Nutr. 2001; 131: 311-18.
48. Tonkiss J, Galler JR,. Prenatal protein malnutrition and working memory performance in adult rats. Behav. Brain Res. 1990; 40: 95-107.
49. Tonkiss J, Galler J, Morgane PJ, Bronzino JD, Austin-Lafrance RJ,. Prenatal protein malnutrition and postnatal brain function. Ann. N. Y. Acad. Sci. 1993; 678: 215-27.
50. Morris MS, Jacques PF, Rosenberg IH, Selhub J,. Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification. Am. J. Clin. Nutr. 2007; 85: 193-200.
51. Algarin C, Peirano P, Garrido M, Pizarro F, Lozoff B,. Iron deficiency anemia in infancy: long-lasting effects on auditory and visual system functioning. Pediatr. Res. 2003; 53: 217-23. 10.1203/01.PDR.0000047657.23156.55.
52. Singh M,. Role of micronutrients for physical growth and mental development. Indian J. Pediatr. 2004; 71: 59-62.
53. Liu J, Raine A,. The effect of childhood malnutrition on externalizing behavior. Curr. Opin. Pediatr. 2006; 18: 565-70.