Ketamine potentiates hippocampal neurodegeneration and persistent learning and memory impairment through the PKCγ-ERK signaling pathway in the developing brain

Brain Research

Volumn 1476, Issue , 2012, Pages 164-171

  Huang, Lining ^a   Liu, Ya ^a   Jin, Wei ^b   Ji, Xiaochen ^a   Dong, Zhenming ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b HEBEI GENERAL HOSPITAL   (China)

Author keywords

Extracellular signal regulated kinase; Hippocampus; Ketamine; Neurodegeneration; Protein kinase C

Indexed keywords

KETAMINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BCL 2; PROTEIN KINASE C GAMMA;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; ENZYME REPRESSION; FEMALE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; HIPPOCAMPUS NEURODEGENERATION; LEARNING DISORDER; MAZE TEST; MEMORY DISORDER; NERVE DEGENERATION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANALGESICS; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BRAIN; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; HIPPOCAMPUS; IN SITU NICK-END LABELING; KETAMINE; LEARNING DISORDERS; MAP KINASE SIGNALING SYSTEM; MAZE LEARNING; MEMORY DISORDERS; NEURODEGENERATIVE DISEASES; PROTEIN KINASE C; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY;

PRIMATES; RATTUS; RODENTIA;

EID: 84866937861     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.07.059     Document Type: Article

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