Prolonged exposure to ketamine increases neurodegeneration in the developing monkey brain

International Journal of Developmental Neuroscience

Volumn 27, Issue 7, 2009, Pages 727-731

  Zou, Xiaoju ^a   Patterson, Tucker A ^a   Divine, Rebecca L ^b   Sadovova, Natalya ^b   Zhang, Xuan ^a   Hanig, Joseph P ^c   Paule, Merle G ^a   Slikker Jr , William ^a   Wang, Cheng ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b Toxicologic Pathology Associates   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Ketamine; Neurotoxicity; NMDA receptor antagonist

Indexed keywords

CASPASE 3; KETAMINE; SILVER;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEGENERATION; BRAIN DEVELOPMENT; BRAIN INJURY; BRAIN TISSUE; CONTROLLED STUDY; CORPUS STRIATUM; DATA ANALYSIS; DRUG EXPOSURE; DRUG INFUSION; FEMALE; FRONTAL CORTEX; GENERAL ANESTHESIA; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; NERVE CELL NECROSIS; NEUROTOXICITY; NEWBORN; NEWBORN PERIOD; NONHUMAN; PEDIATRIC ANESTHESIA; PRIORITY JOURNAL; RHESUS MONKEY; SILVER STAINING; THALAMUS;

ANESTHETICS, DISSOCIATIVE; ANIMALS; BRAIN; CASPASE 3; CELL DEATH; HUMANS; KETAMINE; MACACA MULATTA; NERVE DEGENERATION; NEURONS; ORGANIC CHEMICALS;

ANIMALIA; MACACA MULATTA;

EID: 70349305307     PISSN: 07365748     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2009.06.010     Document Type: Article

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