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Volumn 104, Issue 10, 2012, Pages 571-587

Functions of DNA methyltransferase 3-like in germ cells and beyond

Author keywords

DNA Methyltransferases; Genomic Imprinting; Histone; PiRNA; Retrotransposons

Indexed keywords

DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; DNA METHYLTRANSFERASE 3L; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

EID: 84866934046     PISSN: 02484900     EISSN: 1768322X     Source Type: Journal    
DOI: 10.1111/boc.201100109     Document Type: Review
Times cited : (25)

References (125)
  • 2
    • 0037102492 scopus 로고    scopus 로고
    • Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity
    • Aapola, U., Liiv, I. and Peterson, P. (2002) Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity. Nucleic. Acids Res. 30, 3602-3608
    • (2002) Nucleic. Acids Res. , vol.30 , pp. 3602-3608
    • Aapola, U.1    Liiv, I.2    Peterson, P.3
  • 7
    • 4544223707 scopus 로고    scopus 로고
    • Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L
    • Bourc'his, D. and Bestor, T.H. (2004) Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L. Nature 431, 96-99
    • (2004) Nature , vol.431 , pp. 96-99
    • Bourc'his, D.1    Bestor, T.H.2
  • 8
    • 0035930660 scopus 로고    scopus 로고
    • Dnmt3L and the establishment of maternal genomic imprints
    • Bourc'his, D., Xu, G.L., Lin, C.S., Bollman, B. and Bestor, T.H. (2001) Dnmt3L and the establishment of maternal genomic imprints. Science 294, 2536-2539
    • (2001) Science , vol.294 , pp. 2536-2539
    • Bourc'his, D.1    Xu, G.L.2    Lin, C.S.3    Bollman, B.4    Bestor, T.H.5
  • 10
    • 77950635922 scopus 로고    scopus 로고
    • Maintaining the male germline: regulation of spermatogonial stem cells
    • Caires, K., Broady, J. and McLean, D. (2010) Maintaining the male germline: regulation of spermatogonial stem cells. J. Endocrinol. 205, 133-145
    • (2010) J. Endocrinol. , vol.205 , pp. 133-145
    • Caires, K.1    Broady, J.2    McLean, D.3
  • 11
    • 0037168587 scopus 로고    scopus 로고
    • The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a
    • Chedin, F., Lieber, M.R. and Hsieh, C.L. (2002) The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a. Proc. Natl. Acad. Sci. U. S. A. 99, 16916-16921
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 16916-16921
    • Chedin, F.1    Lieber, M.R.2    Hsieh, C.L.3
  • 12
    • 79955059411 scopus 로고    scopus 로고
    • The DNMT3 family of mammalian de novo DNA methyltransferases
    • Chedin F. (2011) The DNMT3 family of mammalian de novo DNA methyltransferases. Prog. Mol. Biol. Transl. Sci. 101, 255-285
    • (2011) Prog. Mol. Biol. Transl. Sci. , vol.101 , pp. 255-285
    • Chedin, F.1
  • 13
    • 0042132027 scopus 로고    scopus 로고
    • Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b
    • Chen, T., Ueda, Y., Dodge, J.E., Wang, Z. and Li, E. (2003) Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol. Cell. Biol. 23, 5594-5605
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 5594-5605
    • Chen, T.1    Ueda, Y.2    Dodge, J.E.3    Wang, Z.4    Li, E.5
  • 14
    • 26444561533 scopus 로고    scopus 로고
    • Physical and functional interactions between the human DNMT3L protein and members of the de novo methyltransferase family
    • Chen, Z.X., Mann, J.R., Hsieh, C. L., Riggs, A.D. and Chédin, F. (2005) Physical and functional interactions between the human DNMT3L protein and members of the de novo methyltransferase family. J. Cell Biochem. 95, 902-917
    • (2005) J. Cell Biochem , vol.95 , pp. 902-917
    • Chen, Z.X.1    Mann, J.R.2    Hsieh, C.L.3    Riggs, A.D.4    Chédin, F.5
  • 15
    • 4744366752 scopus 로고    scopus 로고
    • The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin
    • Chen, T., Tsujimoto, N. and Li, E. (2004) The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin. Mol. Cell Biol. 24, 9048-9058
    • (2004) Mol. Cell Biol. , vol.24 , pp. 9048-9058
    • Chen, T.1    Tsujimoto, N.2    Li, E.3
  • 16
    • 29644440388 scopus 로고    scopus 로고
    • Establishment and maintenance of DNA methylation patterns in mammals
    • Chen, T. and Li, E. (2006) Establishment and maintenance of DNA methylation patterns in mammals. Curr. Top. Microbiol. Immunol. 301, 179-201
    • (2006) Curr. Top. Microbiol. Immunol. , vol.301 , pp. 179-201
    • Chen, T.1    Li, E.2
  • 17
    • 40049094942 scopus 로고    scopus 로고
    • Mammalian DNA methyltransferases: a structural perspective
    • Cheng, X. and Blumenthal, R.M. (2008) Mammalian DNA methyltransferases: a structural perspective. Structure 16, 341-350
    • (2008) Structure , vol.16 , pp. 341-350
    • Cheng, X.1    Blumenthal, R.M.2
  • 19
    • 70349272130 scopus 로고    scopus 로고
    • KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints
    • Ciccone, D.N., Su, H., Hevi, S., Gay, F., Lei, H., Bajko, J., Xu, G., Li, E. and Chen, T. (2009) KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints. Nature 461, 415-418
    • (2009) Nature , vol.461 , pp. 415-418
    • Ciccone, D.N.1    Su, H.2    Hevi, S.3    Gay, F.4    Lei, H.5    Bajko, J.6    Xu, G.7    Li, E.8    Chen, T.9
  • 20
    • 33747877558 scopus 로고    scopus 로고
    • Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?
    • Costa, Y., Speed, R.M., Gautier, P., Semple, C.A., Maratou, K., Turner, J.M. and Cooke, H.J. (2006) Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway? Hum. Mol. Genet. 15, 2324-2334
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 2324-2334
    • Costa, Y.1    Speed, R.M.2    Gautier, P.3    Semple, C.A.4    Maratou, K.5    Turner, J.M.6    Cooke, H.J.7
  • 22
    • 79959990071 scopus 로고    scopus 로고
    • Regulation of mammalian DNA methyltransferases: a route to new mechanisms
    • Denis, H., Ndlovu, M.N. and Fuks, F. (2011) Regulation of mammalian DNA methyltransferases: a route to new mechanisms. EMBO Rep. 12, 647-656
    • (2011) EMBO Rep. , vol.12 , pp. 647-656
    • Denis, H.1    Ndlovu, M.N.2    Fuks, F.3
  • 24
  • 26
    • 67649305191 scopus 로고    scopus 로고
    • Epigenetics in cancer: targeting chromatin modifications
    • Ellis, L., Atadja, P.W. and Johnstone, R.W. (2009) Epigenetics in cancer: targeting chromatin modifications. Mol. Cancer Ther. 8, 1409-1420
    • (2009) Mol. Cancer Ther. , vol.8 , pp. 1409-1420
    • Ellis, L.1    Atadja, P.W.2    Johnstone, R.W.3
  • 27
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • Esteller M. (2007) Cancer epigenomics: DNA methylomes and histone-modification maps. Nat. Rev. Genet. 8, 286-298
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 286-298
    • Esteller, M.1
  • 29
    • 2642557944 scopus 로고    scopus 로고
    • Regulation of gene activity and repression: a consideration of unifying themes
    • Ferguson-Smith, A.C., Lin, S.P. and Youngson, N. (2004) Regulation of gene activity and repression: a consideration of unifying themes. Curr. Top. Dev. Biol. 60, 197-213
    • (2004) Curr. Top. Dev. Biol. , vol.60 , pp. 197-213
    • Ferguson-Smith, A.C.1    Lin, S.P.2    Youngson, N.3
  • 30
    • 79960530899 scopus 로고    scopus 로고
    • Genomic imprinting: the emergence of an epigenetic paradigm
    • Ferguson-Smith, A.C. (2011) Genomic imprinting: the emergence of an epigenetic paradigm. Nat. Rev. Genet. 12, 565-575
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 565-575
    • Ferguson-Smith, A.C.1
  • 31
    • 2942593748 scopus 로고    scopus 로고
    • Chromatin targeting of de novo DNA methyltransferases by the PWWP domain
    • Ge, Y.Z., Pu, M.T., Gowher, H., Wu, H.P., Ding, J.P., Jeltsch, A. and Xu, G.L. (2004) Chromatin targeting of de novo DNA methyltransferases by the PWWP domain. J. Biol. Chem. 279, 25447-25454
    • (2004) J. Biol. Chem. , vol.279 , pp. 25447-25454
    • Ge, Y.Z.1    Pu, M.T.2    Gowher, H.3    Wu, H.P.4    Ding, J.P.5    Jeltsch, A.6    Xu, G.L.7
  • 32
    • 0025147087 scopus 로고
    • Primordial germ cells in the mouse embryo during gastrulation
    • Ginsburg, M., Snow, M.H. and McLaren, A. (1990) Primordial germ cells in the mouse embryo during gastrulation. Development 110, 521-528
    • (1990) Development , vol.110 , pp. 521-528
    • Ginsburg, M.1    Snow, M.H.2    McLaren, A.3
  • 33
    • 39949083375 scopus 로고    scopus 로고
    • Conserved themes in small-RNA-mediated transposon control
    • Girard, A. and Hannon, G.J. (2008) Conserved themes in small-RNA-mediated transposon control. Trends Cell. Biol. 18, 136-148
    • (2008) Trends Cell. Biol , vol.18 , pp. 136-148
    • Girard, A.1    Hannon, G.J.2
  • 34
    • 72849146835 scopus 로고    scopus 로고
    • CG dinucleotide periodicities recognized by the Dnmt3a-Dnmt3L complex are distinctive at retroelements and imprinted domains
    • Glass, J.L., Fazzari, M.J., Ferguson-Smith, A.C. and Greally, J.M. (2009) CG dinucleotide periodicities recognized by the Dnmt3a-Dnmt3L complex are distinctive at retroelements and imprinted domains. Mamm. Genome 20, 633-643
    • (2009) Mamm. Genome , vol.20 , pp. 633-643
    • Glass, J.L.1    Fazzari, M.J.2    Ferguson-Smith, A.C.3    Greally, J.M.4
  • 36
    • 69949107733 scopus 로고    scopus 로고
    • Reprogramming of HeLa cells upon DNMT3L overexpression mimics carcinogenesis
    • Gokul, G., Ramakrishna, G. and Khosla, S. (2009) Reprogramming of HeLa cells upon DNMT3L overexpression mimics carcinogenesis. Epigenetics 4, 322-329
    • (2009) Epigenetics , vol.4 , pp. 322-329
    • Gokul, G.1    Ramakrishna, G.2    Khosla, S.3
  • 37
    • 52949095077 scopus 로고    scopus 로고
    • Retrotransposons revisited: the restraint and rehabilitation of parasites
    • Goodier, J.L., and Kazazian, H.H. Jr. (2008) Retrotransposons revisited: the restraint and rehabilitation of parasites. Cell 135, 23-35
    • (2008) Cell , vol.135 , pp. 23-35
    • Goodier, J.L.1    Kazazian Jr, H.H.2
  • 38
    • 0037036468 scopus 로고    scopus 로고
    • Molecular enzymology of the catalytic domains of the Dnmt3a and Dnmt3b DNA methyltransferases
    • Gowher, H. and Jeltsch, A. (2002) Molecular enzymology of the catalytic domains of the Dnmt3a and Dnmt3b DNA methyltransferases. J. Biol. Chem. 277, 20409-20414
    • (2002) J. Biol. Chem. , vol.277 , pp. 20409-20414
    • Gowher, H.1    Jeltsch, A.2
  • 41
    • 78149430876 scopus 로고    scopus 로고
    • Molecular coupling of DNA methylation and histone methylation
    • Hashimoto, H., Vertino, P.M. and Cheng, X. (2010) Molecular coupling of DNA methylation and histone methylation. Epigenomics 2, 657-669
    • (2010) Epigenomics , vol.2 , pp. 657-669
    • Hashimoto, H.1    Vertino, P.M.2    Cheng, X.3
  • 42
    • 0036333103 scopus 로고    scopus 로고
    • Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice
    • Hata, K., Okano, M., Lei, H. and Li, E. (2002) Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice. Development 129, 1983-1993
    • (2002) Development , vol.129 , pp. 1983-1993
    • Hata, K.1    Okano, M.2    Lei, H.3    Li, E.4
  • 43
    • 28744442731 scopus 로고    scopus 로고
    • Meiotic and epigenetic aberrations in Dnmt3L-deficient male germ cells
    • Hata, K., Kusumi, M., Yokomine, T., Li, E. and Sasaki, H. (2006) Meiotic and epigenetic aberrations in Dnmt3L-deficient male germ cells. Mol. Reprod. Dev. 73, 116-122
    • (2006) Mol. Reprod. Dev. , vol.73 , pp. 116-122
    • Hata, K.1    Kusumi, M.2    Yokomine, T.3    Li, E.4    Sasaki, H.5
  • 44
    • 69449092535 scopus 로고    scopus 로고
    • Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals
    • Henckel, A., Nakabayashi, K., Sanz, L.A., Feil, R., Hata, K. and Arnaud, P. (2009) Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals. Hum. Mol. Genet. 18, 3375-3383
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 3375-3383
    • Henckel, A.1    Nakabayashi, K.2    Sanz, L.A.3    Feil, R.4    Hata, K.5    Arnaud, P.6
  • 45
    • 84856462767 scopus 로고    scopus 로고
    • Transcription and histone methylation changes correlate with imprint acquisition in male germ cells
    • Henckel, A., Chebli, K., Kota, S. K., Arnaud, P. and Feil, R. (2011) Transcription and histone methylation changes correlate with imprint acquisition in male germ cells. EMBO J. 31, 606-615
    • (2011) EMBO J. , vol.31 , pp. 606-615
    • Henckel, A.1    Chebli, K.2    Kota, S.K.3    Arnaud, P.4    Feil, R.5
  • 46
    • 73449113904 scopus 로고    scopus 로고
    • Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation
    • Hervouet, E., Vallette, F.M. and Cartron, P.F. (2009) Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation. Epigenetics 4, 487-499
    • (2009) Epigenetics , vol.4 , pp. 487-499
    • Hervouet, E.1    Vallette, F.M.2    Cartron, P.F.3
  • 47
    • 77956192737 scopus 로고    scopus 로고
    • Genomic imprinting and human disease
    • Hirasawa R. and Feil, R. (2010) Genomic imprinting and human disease. Essays Biochem. 48, 187-200
    • (2010) Essays Biochem. , vol.48 , pp. 187-200
    • Hirasawa, R.1    Feil, R.2
  • 48
    • 77956504367 scopus 로고    scopus 로고
    • The inherent processivity of the human de novo methyltransferase 3A (DNMT3A) is enhanced by DNMT3L
    • Holz-Schietinger, C. and Reich, N.O. (2010) The inherent processivity of the human de novo methyltransferase 3A (DNMT3A) is enhanced by DNMT3L. J. Biol. Chem. 285, 29091-29100
    • (2010) J. Biol. Chem. , vol.285 , pp. 29091-29100
    • Holz-Schietinger, C.1    Reich, N.O.2
  • 49
    • 82355184502 scopus 로고    scopus 로고
    • Oligomerization of DNMT3A controls the mechanism of de novo DNA methylation
    • Holz-Schietinger, C., Matje, D.M., Flexer Harrison, M. and Reich, N.O. (2011) Oligomerization of DNMT3A controls the mechanism of de novo DNA methylation. J. Biol. Chem. 286, 479-488
    • (2011) J. Biol. Chem. , vol.286 , pp. 479-488
    • Holz-Schietinger, C.1    Matje, D.M.2    Flexer Harrison, M.3    Reich, N.O.4
  • 50
    • 0033499867 scopus 로고    scopus 로고
    • In vivo activity of murine de novo methyltransferases, Dnmt3a and Dnmt3b
    • Hsieh, C.L. (1999) In vivo activity of murine de novo methyltransferases, Dnmt3a and Dnmt3b. Mol. Cell. Biol. 19, 8211-8218
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 8211-8218
    • Hsieh, C.L.1
  • 53
    • 0942287087 scopus 로고    scopus 로고
    • Expression of mRNAs for DNA methyltransferases and methyl-cpg-binding proteins in the human female germ line, preimplantation embryos, and embryonic stem cells
    • Huntriss, J., Hinkins, M., Oliver, B., Harris, S.E., Beazley, J.C., Rutherford, A.J., Gosden, R.G., Lanzendorf, S.E. and Picton, H.M. (2004) Expression of mRNAs for DNA methyltransferases and methyl-cpg-binding proteins in the human female germ line, preimplantation embryos, and embryonic stem cells. Mol. Reprod. Dev. 67, 323-336
    • (2004) Mol. Reprod. Dev. , vol.67 , pp. 323-336
    • Huntriss, J.1    Hinkins, M.2    Oliver, B.3    Harris, S.E.4    Beazley, J.C.5    Rutherford, A.J.6    Gosden, R.G.7    Lanzendorf, S.E.8    Picton, H.M.9
  • 54
    • 58149507192 scopus 로고    scopus 로고
    • Effects of retroviruses on host genome function
    • Jern, P., and Coffin, J.M. (2008) Effects of retroviruses on host genome function. Annu. Rev. Genet. 42, 709-732
    • (2008) Annu. Rev. Genet. , vol.42 , pp. 709-732
    • Jern, P.1    Coffin, J.M.2
  • 55
    • 34548603504 scopus 로고    scopus 로고
    • Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation
    • Jia, D., Jurkowska, R.Z., Zhang, X., Jeltsch, A. and Cheng, X. (2007) Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation. Nature 449, 248-251
    • (2007) Nature , vol.449 , pp. 248-251
    • Jia, D.1    Jurkowska, R.Z.2    Zhang, X.3    Jeltsch, A.4    Cheng, X.5
  • 56
    • 57149094671 scopus 로고    scopus 로고
    • Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L
    • Jurkowska, R.Z., Anspach, N., Urbanke, C., Jia, D., Reinhardt, R., Nellen, W., Cheng, X. and Jeltsch, A. (2008) Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L. Nucleic Acids Res. 236, 6656-6663
    • (2008) Nucleic Acids Res. , vol.236 , pp. 6656-6663
    • Jurkowska, R.Z.1    Anspach, N.2    Urbanke, C.3    Jia, D.4    Reinhardt, R.5    Nellen, W.6    Cheng, X.7    Jeltsch, A.8
  • 57
    • 79959900027 scopus 로고    scopus 로고
    • Oligomerization and binding of the Dnmt3a DNA methyltransferase to parallel DNA molecules: heterochromatic localization and role of Dnmt3L
    • Jurkowska, R.Z., Rajavelu, A., Anspach, N., Urbanke, C., Jankevicius, G., Ragozin, S., Nellen, W. and Jeltsch, A. (2011) Oligomerization and binding of the Dnmt3a DNA methyltransferase to parallel DNA molecules: heterochromatic localization and role of Dnmt3L. J. Biol. Chem. 286, 24200-24207
    • (2011) J. Biol. Chem. , vol.286 , pp. 24200-24207
    • Jurkowska, R.Z.1    Rajavelu, A.2    Anspach, N.3    Urbanke, C.4    Jankevicius, G.5    Ragozin, S.6    Nellen, W.7    Jeltsch, A.8
  • 58
    • 3042584653 scopus 로고    scopus 로고
    • Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting
    • Kaneda, M., Okano, M., Hata, K., Sado, T., Tsujimoto, N., Li, E. and Sasaki, H. (2004a) Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature. 429, 900-903
    • (2004) Nature , vol.429 , pp. 900-903
    • Kaneda, M.1    Okano, M.2    Hata, K.3    Sado, T.4    Tsujimoto, N.5    Li, E.6    Sasaki, H.7
  • 59
  • 60
    • 77950641592 scopus 로고    scopus 로고
    • Genetic evidence for Dnmt3a-dependent imprinting during oocyte growth obtained by conditional knockout with Zp3-Cre and complete exclusion of Dnmt3b by chimera formation
    • Kaneda, M., Hirasawa, R., Chiba, H., Okano, M., Li, E. and Sasaki, H. (2010) Genetic evidence for Dnmt3a-dependent imprinting during oocyte growth obtained by conditional knockout with Zp3-Cre and complete exclusion of Dnmt3b by chimera formation. Genes Cells 15, 169-179
    • (2010) Genes Cells , vol.15 , pp. 169-179
    • Kaneda, M.1    Hirasawa, R.2    Chiba, H.3    Okano, M.4    Li, E.5    Sasaki, H.6
  • 61
    • 33748740832 scopus 로고    scopus 로고
    • Reconstitution and mechanism of the stimulation of de novo methylation by human DNMT3L
    • Kareta, M.S., Botello, Z.M., Ennis, J.J., Chou, C. and Chédin, F. (2006) Reconstitution and mechanism of the stimulation of de novo methylation by human DNMT3L. J. Biol. Chem. 281, 25893-25902
    • (2006) J. Biol. Chem. , vol.281 , pp. 25893-25902
    • Kareta, M.S.1    Botello, Z.M.2    Ennis, J.J.3    Chou, C.4    Chédin, F.5
  • 62
    • 34548705374 scopus 로고    scopus 로고
    • Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse
    • Kato, Y., Kaneda, M., Hata, K., Kumaki, K., Hisano, M., Kohara, Y., Okano, M., Li, E., Nozaki, M. and Sasaki, H. (2007) Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse. Hum. Mol. Genet. 16, 2272-2280
    • (2007) Hum. Mol. Genet. , vol.16 , pp. 2272-2280
    • Kato, Y.1    Kaneda, M.2    Hata, K.3    Kumaki, K.4    Hisano, M.5    Kohara, Y.6    Okano, M.7    Li, E.8    Nozaki, M.9    Sasaki, H.10
  • 63
    • 77951566673 scopus 로고    scopus 로고
    • DNA methyltransferase 3-like affects promoter methylation of thymine DNA glycosylase independently of DNMT1 and DNMT3B in cancer cells
    • Kim, H., Park, J., Jung, Y., Song, S.H., Han, S.W., Oh, D.Y., Im, S.A., Bang, Y.J. and Kim, T.Y. (2010) DNA methyltransferase 3-like affects promoter methylation of thymine DNA glycosylase independently of DNMT1 and DNMT3B in cancer cells. Int. J. Oncol. 36, 1563-1572
    • (2010) Int. J. Oncol. , vol.36 , pp. 1563-1572
    • Kim, H.1    Park, J.2    Jung, Y.3    Song, S.H.4    Han, S.W.5    Oh, D.Y.6    Im, S.A.7    Bang, Y.J.8    Kim, T.Y.9
  • 64
    • 32344450824 scopus 로고    scopus 로고
    • Genomic DNA methylation: the mark and its mediators.
    • Klose, R.J. and Bird, A.P. (2006) Genomic DNA methylation: the mark and its mediators. Trends Biochem. Sci. 31, 89-97
    • (2006) Trends Biochem. Sci , vol.31 , pp. 89-97
    • Klose, R.J.1    Bird, A.P.2
  • 66
    • 69549128557 scopus 로고    scopus 로고
    • The function of non-coding RNAs in genomic imprinting
    • Koerner, M.V., Pauler, F.M., Huang, R. and Barlow, D.P. (2009) The function of non-coding RNAs in genomic imprinting. Development 136, 1771-1783
    • (2009) Development , vol.136 , pp. 1771-1783
    • Koerner, M.V.1    Pauler, F.M.2    Huang, R.3    Barlow, D.P.4
  • 68
    • 38649127832 scopus 로고    scopus 로고
    • Loss of spermatogonia and wide-spread DNA methylation defects in newborn male mice deficient in dnmt3l.
    • La Salle, S., Oakes, C.C., Neaga, O.R., Bourc'his, D., Bestor, T.H. and Trasler, J.M. (2007) Loss of spermatogonia and wide-spread DNA methylation defects in newborn male mice deficient in dnmt3l. BMC Dev. Biol. 7, 104
    • (2007) BMC Dev. Biol. , vol.7 , pp. 104
    • La Salle, S.1    Oakes, C.C.2    Neaga, O.R.3    Bourc'his, D.4    Bestor, T.H.5    Trasler, J.M.6
  • 69
    • 16244376842 scopus 로고    scopus 로고
    • DNA methyltransferase expression in the mouse germ line during periods of de novo methylation
    • Lees-Murdock, D.J., Shovlin, T.C., Gardiner, T., De Felici, M. and Walsh, C.P. (2005) DNA methyltransferase expression in the mouse germ line during periods of de novo methylation. Dev. Dyn. 232, 992-1002
    • (2005) Dev. Dyn. , vol.232 , pp. 992-1002
    • Lees-Murdock, D.J.1    Shovlin, T.C.2    Gardiner, T.3    De Felici, M.4    Walsh, C.P.5
  • 70
    • 42149101071 scopus 로고    scopus 로고
    • DNA methylation reprogramming in the germ line
    • Lees-Murdock, D.J. and Walsh, C.P. (2008) DNA methylation reprogramming in the germ line. Epigenetics 3, 5-13
    • (2008) Epigenetics , vol.3 , pp. 5-13
    • Lees-Murdock, D.J.1    Walsh, C.P.2
  • 71
    • 7944221225 scopus 로고    scopus 로고
    • Timing of establishment of paternal methylation imprints in the mouse
    • Li, J.Y., Lees-Murdock D.J., Xu, G.L. and Walsh, C.P. (2004) Timing of establishment of paternal methylation imprints in the mouse. Genomics 84, 952-960
    • (2004) Genomics , vol.84 , pp. 952-960
    • Li, J.Y.1    Lees-Murdock., D.2    Xu, G.L.3    Walsh, C.P.4
  • 72
    • 53249098795 scopus 로고    scopus 로고
    • A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints
    • Li, X., Ito, M., Zhou, F., Youngson, N., Zuo, X., Leder, P. and Ferguson-Smith, A.C. (2008) A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints. Dev. Cell. 15, 547-557
    • (2008) Dev. Cell. , vol.15 , pp. 547-557
    • Li, X.1    Ito, M.2    Zhou, F.3    Youngson, N.4    Zuo, X.5    Leder, P.6    Ferguson-Smith, A.C.7
  • 73
    • 79952535798 scopus 로고    scopus 로고
    • Genomic imprinting in mammals: its life cycle, molecular mechanisms and reprogramming
    • Li, Y. and Sasaki, H. (2011) Genomic imprinting in mammals: its life cycle, molecular mechanisms and reprogramming. Cell Res. 21, 466-473
    • (2011) Cell Res. , vol.21 , pp. 466-473
    • Li, Y.1    Sasaki, H.2
  • 74
    • 0042856381 scopus 로고    scopus 로고
    • Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12
    • Lin, S.P., Youngson, N., Takada, S., Seitz, H., Reik, W., Paulsen, M., Cavaille, J. and Ferguson-Smith, A.C. (2003) Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12. Nat. Genet. 35, 97-102
    • (2003) Nat. Genet. , vol.35 , pp. 97-102
    • Lin, S.P.1    Youngson, N.2    Takada, S.3    Seitz, H.4    Reik, W.5    Paulsen, M.6    Cavaille, J.7    Ferguson-Smith, A.C.8
  • 75
    • 33846977748 scopus 로고    scopus 로고
    • Differential regulation of imprinting in the murine embryo and placenta by the Dlk1-Dio3 imprinting control region
    • Lin, S.P., Coan, P., da Rocha, S.T., Seitz, H., Cavaille, J., Teng, P.W., Takada, S. and Ferguson-Smith, A.C. (2007) Differential regulation of imprinting in the murine embryo and placenta by the Dlk1-Dio3 imprinting control region. Development 134, 417-426
    • (2007) Development , vol.134 , pp. 417-426
    • Lin, S.P.1    Coan, P.2    da Rocha, S.T.3    Seitz, H.4    Cavaille, J.5    Teng, P.W.6    Takada, S.7    Ferguson-Smith, A.C.8
  • 76
    • 77957338939 scopus 로고    scopus 로고
    • Genomic imprinting syndromes and cancer.
    • Lim, D.H. and Maher, E.R. (2010) Genomic imprinting syndromes and cancer. Adv. Genet. 70, 145-175
    • (2010) Adv. Genet , vol.70 , pp. 145-175
    • Lim, D.H.1    Maher, E.R.2
  • 79
    • 55549102967 scopus 로고    scopus 로고
    • Keeping active endogenous retroviral-like elements in check: the epigenetic perspective
    • Maksakova, I.A., Mager, D.L. and Reiss, D. (2008) Keeping active endogenous retroviral-like elements in check: the epigenetic perspective. Cell. Mol. Life Sci. 65, 3329-3347
    • (2008) Cell. Mol. Life Sci. , vol.65 , pp. 3329-3347
    • Maksakova, I.A.1    Mager, D.L.2    Reiss, D.3
  • 82
    • 33745713437 scopus 로고    scopus 로고
    • It takes a PHD to read the histone code
    • Mellor J. (2006) It takes a PHD to read the histone code. Cell 126, 22-24
    • (2006) Cell , vol.126 , pp. 22-24
    • Mellor, J.1
  • 84
    • 77954715161 scopus 로고    scopus 로고
    • L1 retrotransposon and retinoblastoma: molecular linkages between epigenetics and cancer
    • Montoya-Durango, D.E., Ramos, K.S. (2010) L1 retrotransposon and retinoblastoma: molecular linkages between epigenetics and cancer. Curr. Mol. Med. 10, 511-521
    • (2010) Curr. Mol. Med. , vol.10 , pp. 511-521
    • Montoya-Durango, D.E.1    Ramos, K.S.2
  • 85
    • 79953858658 scopus 로고    scopus 로고
    • No-nonsense functions for long noncoding RNAs
    • Nagano, T. and Fraser, P. (2011) No-nonsense functions for long noncoding RNAs. Cell. 145, 178-181
    • (2011) Cell , vol.145 , pp. 178-181
    • Nagano, T.1    Fraser, P.2
  • 86
    • 54949102311 scopus 로고    scopus 로고
    • Regulation of spermatogonial stem cell self-renewal in mammals
    • Oatley, J.M. and Brinster, R.L. (2008) Regulation of spermatogonial stem cell self-renewal in mammals. Annu. Rev. Cell Dev. Biol. 24, 263-286
    • (2008) Annu. Rev. Cell Dev. Biol , vol.24 , pp. 263-286
    • Oatley, J.M.1    Brinster, R.L.2
  • 87
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano, M., Bell, D.W., Haber, D.A. and Li, E. (1999) DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99, 247-257
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 90
    • 70449099301 scopus 로고    scopus 로고
    • Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain
    • Otani, J., Nankumo, T., Arita, K., Inamoto, S., Ariyoshi, M. and Shirakawa, M. (2009) Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain. EMBO Rep. 10, 1235-1241
    • (2009) EMBO Rep. , vol.10 , pp. 1235-1241
    • Otani, J.1    Nankumo, T.2    Arita, K.3    Inamoto, S.4    Ariyoshi, M.5    Shirakawa, M.6
  • 91
    • 79956318370 scopus 로고    scopus 로고
    • De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state
    • Pawlak M and Jaenisch, R. (2011) De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state. Genes Dev. 25, 1035-1040
    • (2011) Genes Dev. , vol.25 , pp. 1035-1040
    • Pawlak, M.1    Jaenisch, R.2
  • 92
    • 22844457491 scopus 로고    scopus 로고
    • DNA methylation and human disease
    • Robertson, K.D. (2005) DNA methylation and human disease. Nat. Rev. Genet. 8, 597-610
    • (2005) Nat. Rev. Genet. , vol.8 , pp. 597-610
    • Robertson, K.D.1
  • 94
    • 79957562088 scopus 로고    scopus 로고
    • Developmental control of imprinted expression by macro non-coding RNAs
    • Santoro, F. and Barlow, D.P. (2011) Developmental control of imprinted expression by macro non-coding RNAs. Semin Cell Dev. Biol. 22, 328-335
    • (2011) Semin Cell Dev. Biol. , vol.22 , pp. 328-335
    • Santoro, F.1    Barlow, D.P.2
  • 95
    • 38349100549 scopus 로고    scopus 로고
    • Epigenetic events in mammalian germ-cell development: reprogramming and beyond
    • Sasaki, H., and Matsui, Y. (2008) Epigenetic events in mammalian germ-cell development: reprogramming and beyond. Nat. Rev. Genet. 9, 129-140
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 129-140
    • Sasaki, H.1    Matsui, Y.2
  • 96
    • 33751204468 scopus 로고    scopus 로고
    • Pathway to totipotency: lessons from germ cells
    • Seydoux, G. and Braun, R.E. (2006) Pathway to totipotency: lessons from germ cells. Cell 127, 891-904
    • (2006) Cell , vol.127 , pp. 891-904
    • Seydoux, G.1    Braun, R.E.2
  • 99
    • 81955162265 scopus 로고    scopus 로고
    • Piwis and piwi-interacting RNAs in the epigenetics of cancer
    • Siddiqi, S. and Matushansky, I. (2011) Piwis and piwi-interacting RNAs in the epigenetics of cancer. J. Cell. Biochem. 113, 373-380
    • (2011) J. Cell. Biochem , vol.113 , pp. 373-380
    • Siddiqi, S.1    Matushansky, I.2
  • 100
    • 66049130912 scopus 로고    scopus 로고
    • RNA silencing in germlines-exquisite collaboration of Argonaute proteins with small RNAs for germline survival
    • Siomi, M.C. and Kuramochi-Miyagawa S. (2009) RNA silencing in germlines-exquisite collaboration of Argonaute proteins with small RNAs for germline survival. Curr. Opin. Cell Biol. 21, 426-434
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 426-434
    • Siomi, M.C.1    Kuramochi-Miyagawa, S.2
  • 104
    • 84655164284 scopus 로고    scopus 로고
    • De novo DNA methylation: a germ cell perspective
    • Smallwood, S.A. and Kelsey, G. (2011) De novo DNA methylation: a germ cell perspective. Trends Genet. 28, 33-42
    • (2011) Trends Genet. , vol.28 , pp. 33-42
    • Smallwood, S.A.1    Kelsey, G.2
  • 105
  • 106
    • 55549096355 scopus 로고    scopus 로고
    • Murine endogenous retroviruses
    • Stocking, C. and Kozak, C.A. (2008) Murine endogenous retroviruses. Cell Mol. Life Sci. 65, 3383-3398
    • (2008) Cell Mol. Life Sci. , vol.65 , pp. 3383-3398
    • Stocking, C.1    Kozak, C.A.2
  • 107
    • 3042641718 scopus 로고    scopus 로고
    • DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction
    • Suetake, I., Shinozaki, F., Miyagawa, J., Takeshima, H. and Tajima, S. (2004) DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction. J. Biol. Chem. 279, 27816-27823
    • (2004) J. Biol. Chem. , vol.279 , pp. 27816-27823
    • Suetake, I.1    Shinozaki, F.2    Miyagawa, J.3    Takeshima, H.4    Tajima, S.5
  • 110
    • 70350238350 scopus 로고    scopus 로고
    • The biogenesis and function of PIWI proteins and piRNAs: progress and prospect
    • Thomson, T. and Lin, H. (2009) The biogenesis and function of PIWI proteins and piRNAs: progress and prospect. Annu. Rev. Cell Dev. Biol. 25, 355-376
    • (2009) Annu. Rev. Cell Dev. Biol. , vol.25 , pp. 355-376
    • Thomson, T.1    Lin, H.2
  • 111
    • 0028925748 scopus 로고
    • Tightly regulated, developmentally specific expression of the first open reading frame from LINE-1 during mouse embryogenesis
    • Trelogan, S.A. and Martin, S.L. (1995) Tightly regulated, developmentally specific expression of the first open reading frame from LINE-1 during mouse embryogenesis. Proc. Natl. Acad Sci. U.S.A. 92, 1520-1524
    • (1995) Proc. Natl. Acad Sci. U.S.A. , vol.92 , pp. 1520-1524
    • Trelogan, S.A.1    Martin, S.L.2
  • 113
    • 79958074728 scopus 로고    scopus 로고
    • Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants
    • Van Emburgh, B.O. and Robertson, K.D. (2011) Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants. Nucleic Acids Res. 39, 4984-5002
    • (2011) Nucleic Acids Res. , vol.39 , pp. 4984-5002
    • Van Emburgh, B.O.1    Robertson, K.D.2
  • 114
    • 78649635700 scopus 로고    scopus 로고
    • Bodies of evidence - compartmentalization of the piRNA pathway in mouse fetal prospermatogonia
    • van der Heijden, G.W., Castañeda, J. and Bortvin, A. (2010) Bodies of evidence - compartmentalization of the piRNA pathway in mouse fetal prospermatogonia. Curr. Opin. Cell. Biol. 22, 752-757
    • (2010) Curr. Opin. Cell. Biol. , vol.22 , pp. 752-757
    • van der Heijden, G.W.1    Castañeda, J.2    Bortvin, A.3
  • 119
    • 78049415018 scopus 로고    scopus 로고
    • DNMT3L modulates significant and distinct flanking sequence preference for DNA methylation by DNMT3A and DNMT3B in vivo
    • Wienholz, B.L., Kareta, M.S., Moarefi, A.H., Gordon, C.A., Ginno, P.A. and Chédin, F. (2010) DNMT3L modulates significant and distinct flanking sequence preference for DNA methylation by DNMT3A and DNMT3B in vivo. PLoS Genet. 6, e1001106
    • (2010) PLoS Genet. , vol.6
    • Wienholz, B.L.1    Kareta, M.S.2    Moarefi, A.H.3    Gordon, C.A.4    Ginno, P.A.5    Chédin, F.6
  • 121
    • 84857331867 scopus 로고    scopus 로고
    • Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome
    • Xie, W., Barr, C.L., Kim, A., Yue, F., Lee, A.Y., Eubanks, J., Dempster, E.L. and Ren, B. (2012) Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome. Cell 148, 816-831
    • (2012) Cell , vol.148 , pp. 816-831
    • Xie, W.1    Barr, C.L.2    Kim, A.3    Yue, F.4    Lee, A.Y.5    Eubanks, J.6    Dempster, E.L.7    Ren, B.8
  • 123
    • 33645452014 scopus 로고    scopus 로고
    • Evolution of the vertebrate DNMT3 gene family: a possible link between existence of DNMT3L and genomic imprinting
    • Yokomine, T., Hata, K., Tsudzuki, M. and Sasaki, H. (2006) Evolution of the vertebrate DNMT3 gene family: a possible link between existence of DNMT3L and genomic imprinting. Cytogenet. Genome Res. 113, 75-80
    • (2006) Cytogenet. Genome Res. , vol.113 , pp. 75-80
    • Yokomine, T.1    Hata, K.2    Tsudzuki, M.3    Sasaki, H.4


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