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Volumn 47, Issue 1, 2012, Pages 17-27

Cellular immunotherapy using dendritic cells against multiple myeloma

Author keywords

Cellular immunotherapy; Cytotoxic tlymphocyte; Dendritic cell; Immune response; Multiple myeloma

Indexed keywords

ALPHA INTERFERON; APC 8020; CD38 ANTIGEN; CD74 ANTIGEN; CHEMOKINE RECEPTOR CCR7; DENDRITIC CELL VACCINE; DICKKOPF 1 PROTEIN; GAMMA INTERFERON; GLYCOPROTEIN GP 96; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN IDIOTYPE; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 1BETA; INTERLEUKIN 6; MULTIPLE MYELOMA VACCINE; NY ESO 1 ANTIGEN; PROSTAGLANDIN E2; SIPULEUCEL T; STAT3 PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR AGONIST; TRANSFORMING GROWTH FACTOR BETA; TUMOR ANTIGEN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; URSOLIC ACID; VASCULOTROPIN; WT1 PROTEIN;

EID: 84866888250     PISSN: 17387949     EISSN: 20929129     Source Type: Journal    
DOI: 10.5045/kjh.2012.47.1.17     Document Type: Review
Times cited : (10)

References (89)
  • 2
    • 64749106320 scopus 로고    scopus 로고
    • The role of high-dose therapy with autologous stem cell support in the era of novel agents
    • Attal M, Harousseau JL. The role of high-dose therapy with autologous stem cell support in the era of novel agents. Semin Hematol 2009;46:127-32.
    • (2009) Semin Hematol , vol.46 , pp. 127-132
    • Attal, M.1    Harousseau, J.L.2
  • 3
    • 0344511759 scopus 로고    scopus 로고
    • Chronic but not acute graft-versus-host disease improves outcome in multiple myeloma patients after non-myeloablative allogeneic transplantation
    • Perez-Simón JA, Martino R, Alegre A, et al. Chronic but not acute graft-versus-host disease improves outcome in multiple myeloma patients after non-myeloablative allogeneic transplantation. Br J Haematol 2003;121:104-8.
    • (2003) Br J Haematol. , vol.121 , pp. 104-108
    • Perez-simón, J.A.1    Martino, R.2    Alegre, A.3
  • 6
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998;392:245-52.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 7
    • 0035052360 scopus 로고    scopus 로고
    • Dendritic cells and immunotherapy for malignant disease
    • Reid DC. Dendritic cells and immunotherapy for malignant disease. Br J Haematol 2001;112:874-87.
    • (2001) Br J Haematol. , vol.112 , pp. 874-887
    • Reid, D.C.1
  • 8
    • 0346096827 scopus 로고    scopus 로고
    • The first 1000 dendritic cell vaccinees
    • Ridgway D. The first 1000 dendritic cell vaccinees. Cancer Invest 2003;21:873-86.
    • (2003) Cancer Invest. , vol.21 , pp. 873-886
    • Ridgway, D.1
  • 9
    • 17144417748 scopus 로고    scopus 로고
    • Dendritic cells as therapeutic vaccines against cancer
    • Banchereau J, Palucka AK. Dendritic cells as therapeutic vaccines against cancer. Nat Rev Immunol 2005;5:296-306.
    • (2005) Nat Rev Immunol. , vol.5 , pp. 296-306
    • Banchereau, J.1    Palucka, A.K.2
  • 10
    • 34047220868 scopus 로고    scopus 로고
    • Cancer immunoediting from immune surveillance to immune escape
    • Kim R, Emi M, Tanabe K. Cancer immunoediting from immune surveillance to immune escape. Immunology 2007;121:1-14.
    • (2007) Immunology , vol.121 , pp. 1-14
    • Kim, R.1    Emi, M.2    Tanabe, K.3
  • 11
    • 74249089972 scopus 로고    scopus 로고
    • Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma
    • Quach H, Ritchie D, Stewart AK, et al. Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma. Leukemia 2010;24:22-32.
    • (2010) Leukemia , vol.24 , pp. 22-32
    • Quach, H.1    Ritchie, D.2    Stewart, A.K.3
  • 12
    • 0035892109 scopus 로고    scopus 로고
    • Dendritic cells from patients with myeloma are numerically normal but functionally defective as they fail to up-regulate CD80 (B7-1) expression after huCD40LT stimulation because of inhibition by transforming growth factorbeta1 and interleukin-10
    • Brown RD, Pope B, Murray A, et al. Dendritic cells from patients with myeloma are numerically normal but functionally defective as they fail to up-regulate CD80 (B7-1) expression after huCD40LT stimulation because of inhibition by transforming growth factorbeta1 and interleukin-10. Blood 2001;98:2992-8.
    • (2001) Blood , vol.98 , pp. 2992-2998
    • Brown, R.D.1    Pope, B.2    Murray, A.3
  • 13
    • 0036659945 scopus 로고    scopus 로고
    • Dendritic cells are functionally defective in multiple myeloma: the role of interleukin-6
    • Ratta M, Fagnoni F, Curti A, et al. Dendritic cells are functionally defective in multiple myeloma: the role of interleukin-6. Blood 2002;100:230-7.
    • (2002) Blood , vol.100 , pp. 230-237
    • Ratta, M.1    Fagnoni, F.2    Curti, A.3
  • 14
    • 33845865825 scopus 로고    scopus 로고
    • Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment
    • Yu H, Kortylewski M, Pardoll D. Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev Immunol 2007;7:41-51.
    • (2007) Nat Rev Immunol. , vol.7 , pp. 41-51
    • Yu, H.1    Kortylewski, M.2    Pardoll, D.3
  • 15
    • 10644224388 scopus 로고    scopus 로고
    • High Th1/Th2 ratio in patients with multiple myeloma
    • Ogawara H, Handa H, Yamazaki T, et al. High Th1/Th2 ratio in patients with multiple myeloma. Leuk Res 2005;29:135-40.
    • (2005) Leuk Res. , vol.29 , pp. 135-140
    • Ogawara, H.1    Handa, H.2    Yamazaki, T.3
  • 16
    • 0038268128 scopus 로고    scopus 로고
    • Viral antigen-specific CD8+ T-cell responses are impaired in multiple myeloma
    • Maecker B, Anderson KS, von Bergwelt-Baildon MS, et al. Viral antigen-specific CD8+ T-cell responses are impaired in multiple myeloma. Br J Haematol 2003;121:842-8.
    • (2003) Br J Haematol. , vol.121 , pp. 842-848
    • Maecker, B.1    Anderson, K.S.2    Bergwelt-baildon, M.S.V.3
  • 17
    • 0038543513 scopus 로고    scopus 로고
    • A reversible defect in natural killer T cell function characterizes the progression of premalignant to malignant multiple myeloma
    • Dhodapkar MV, Geller MD, Chang DH, et al. A reversible defect in natural killer T cell function characterizes the progression of premalignant to malignant multiple myeloma. J Exp Med 2003;197:1667-76.
    • (2003) J Exp Med. , vol.197 , pp. 1667-1676
    • Dhodapkar, M.V.1    Geller, M.D.2    Chang, D.H.3
  • 18
    • 34247507209 scopus 로고    scopus 로고
    • Blockade of natural killer cell-mediated lysis by NCAM140 expressed on tumor cells
    • Jarahian M, Watzl C, Issa Y, Altevogt P, Momburg F. Blockade of natural killer cell-mediated lysis by NCAM140 expressed on tumor cells. Int J Cancer 2007;120:2625-34.
    • (2007) Int J Cancer , vol.120 , pp. 2625-2634
    • Jarahian, M.1    Watzl, C.2    Issa, Y.3    Altevogt, P.4    Momburg, F.5
  • 19
    • 30144444962 scopus 로고    scopus 로고
    • Dysfunctional T regulatory cells in multiple myeloma
    • Prabhala RH, Neri P, Bae JE, et al. Dysfunctional T regulatory cells in multiple myeloma. Blood 2006;107:301-4.
    • (2006) Blood , vol.107 , pp. 301-304
    • Prabhala, R.H.1    Neri, P.2    Bae, J.E.3
  • 20
    • 33750614944 scopus 로고    scopus 로고
    • Expansion of FOXP3 high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients
    • Banerjee DK, Dhodapkar MV, Matayeva E, Steinman RM, Dhodapkar KM. Expansion of FOXP3 high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients. Blood 2006;108: 2655-61.
    • (2006) Blood , vol.108 , pp. 2655-2661
    • Banerjee, D.K.1    Dhodapkar, M.V.2    Matayeva, E.3    Steinman, R.M.4    Dhodapkar, K.M.5
  • 21
    • 65249138393 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: linking inflammation and cancer
    • Ostrand-Rosenberg S, Sinha P. Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol 2009;182:4499-506.
    • (2009) J Immunol. , vol.182 , pp. 4499-4506
    • Ostrand-rosenberg, S.1    Sinha, P.2
  • 22
    • 78149270433 scopus 로고    scopus 로고
    • Increased level of both CD4+FOXP3+ regulatory T cells and CD14+HLA-DR-/low myeloid-derived suppressor cells and decreased level of dendritic cells in patients with multiple myeloma
    • Brimnes MK, Vangsted AJ, Knudsen LM, et al. Increased level of both CD4+FOXP3+ regulatory T cells and CD14+HLA-DR-/low myeloid-derived suppressor cells and decreased level of dendritic cells in patients with multiple myeloma. Scand J Immunol 2010;72:540-7.
    • (2010) Scand J Immunol. , vol.72 , pp. 540-547
    • Brimnes, M.K.1    Vangsted, A.J.2    Knudsen, L.M.3
  • 23
    • 0028914441 scopus 로고
    • Transfer of myeloma idiotype-specific immunity from an actively immunised marrow donor
    • Kwak LW, Taub DD, Duffey PL, et al. Transfer of myeloma idiotype-specific immunity from an actively immunised marrow donor. Lancet 1995;345:1016-20.
    • (1995) Lancet. , vol.345 , pp. 1016-1020
    • Kwak, L.W.1    Taub, D.D.2    Duffey, P.L.3
  • 24
    • 0029983701 scopus 로고    scopus 로고
    • Modulation of antiidiotypic immune response by immunization with the autologous M-component protein in multiple myeloma patients
    • Bergenbrant S, Yi Q, Osterborg A, et al. Modulation of antiidiotypic immune response by immunization with the autologous M-component protein in multiple myeloma patients. Br J Haematol 1996;92:840-6.
    • (1996) Br J Haematol. , vol.92 , pp. 840-846
    • Bergenbrant, S.1    Yi, Q.2    Osterborg, A.3
  • 25
    • 0034667620 scopus 로고    scopus 로고
    • Tumor-specific recognition of human myeloma cells by idiotype-induced CD8(+) T cells
    • Li Y, Bendandi M, Deng Y, et al. Tumor-specific recognition of human myeloma cells by idiotype-induced CD8(+) T cells. Blood 2000;96:2828-33.
    • (2000) Blood , vol.96 , pp. 2828-2833
    • Li, Y.1    Bendandi, M.2    Deng, Y.3
  • 26
    • 0035869383 scopus 로고    scopus 로고
    • Idiotype-specific cytotoxic T lymphocytes in multiple myeloma: evidence for their capacity to lyse autologous primary tumor cells
    • Wen YJ, Barlogie B, Yi Q. Idiotype-specific cytotoxic T lymphocytes in multiple myeloma: evidence for their capacity to lyse autologous primary tumor cells. Blood 2001;97:1750-5.
    • (2001) Blood , vol.97 , pp. 1750-1755
    • Wen, Y.J.1    Barlogie, B.2    Yi, Q.3
  • 27
    • 0035166483 scopus 로고    scopus 로고
    • Dendritic cells derived from multiple myeloma patients efficiently internalize different classes of myeloma protein
    • Butch AW, Kelly KA, Munshi NC. Dendritic cells derived from multiple myeloma patients efficiently internalize different classes of myeloma protein. Exp Hematol 2001;29:85-92.
    • (2001) Exp Hematol. , vol.29 , pp. 85-92
    • Butch, A.W.1    Kelly, K.A.2    Munshi, N.C.3
  • 28
    • 0032834303 scopus 로고    scopus 로고
    • Idiotypic protein-pulsed dendritic cell vaccination in multiple myeloma
    • Lim SH, Bailey-Wood R. Idiotypic protein-pulsed dendritic cell vaccination in multiple myeloma. Int J Cancer 1999;83:215-22.
    • (1999) Int J Cancer. , vol.83 , pp. 215-222
    • Lim, S.H.1    Bailey-wood, R.2
  • 29
    • 0033655655 scopus 로고    scopus 로고
    • Idiotype vaccination using dendritic cells after autologous peripheral blood progenitor cell transplantation for multiple myeloma
    • Liso A, Stockerl-Goldstein KE, Auffermann-Gretzinger S, et al. Idiotype vaccination using dendritic cells after autologous peripheral blood progenitor cell transplantation for multiple myeloma. Biol Blood Marrow Transplant 2000;6:621-7.
    • (2000) Biol Blood Marrow Transplant , vol.6 , pp. 621-627
    • Liso, A.1    Stockerl-goldstein, K.E.2    Auffermann-gretzinger, S.3
  • 30
    • 0034025657 scopus 로고    scopus 로고
    • Vaccination of multiple myeloma patients with idiotype-pulsed dendritic cells: immunological and clinical aspects
    • Titzer S, Christensen O, Manzke O, et al. Vaccination of multiple myeloma patients with idiotype-pulsed dendritic cells: immunological and clinical aspects. Br J Haematol 2000;108:805-16.
    • (2000) Br J Haematol. , vol.108 , pp. 805-816
    • Titzer, S.1    Christensen, O.2    Manzke, O.3
  • 31
    • 0036243105 scopus 로고    scopus 로고
    • Optimizing dendritic cell-based immunotherapy in multiple myeloma
    • Yi Q, Desikan R, Barlogie B, Munshi N. Optimizing dendritic cell-based immunotherapy in multiple myeloma. Br J Haematol 2002;117:297-305.
    • (2002) Br J Haematol. , vol.117 , pp. 297-305
    • Yi, Q.1    Desikan, R.2    Barlogie, B.3    Munshi, N.4
  • 32
    • 0242330773 scopus 로고    scopus 로고
    • Idiotype vaccination of multiple myeloma patients using monocyte-derived dendritic cells
    • Reichardt VL, Milazzo C, Brugger W, Einsele H, Kanz L, Brossart P. Idiotype vaccination of multiple myeloma patients using monocyte-derived dendritic cells. Haematologica 2003;88:1139-49.
    • (2003) Haematologica , vol.88 , pp. 1139-1149
    • Reichardt, V.L.1    Milazzo, C.2    Brugger, W.3    Einsele, H.4    Kanz, L.5    Brossart, P.6
  • 33
    • 30844450344 scopus 로고    scopus 로고
    • Combined vaccination with idiotype-pulsed allogeneic dendritic cells and soluble protein idiotype for multiple myeloma patients relapsing after reduced-intensity conditioning allogeneic stem cell transplantation
    • Bendandi M, Rodríguez-Calvillo M, Inogés S, et al. Combined vaccination with idiotype-pulsed allogeneic dendritic cells and soluble protein idiotype for multiple myeloma patients relapsing after reduced-intensity conditioning allogeneic stem cell transplantation. Leuk Lymphoma 2006;47:29-37.
    • (2006) Leuk Lymphoma , vol.47 , pp. 29-37
    • Bendandi, M.1    Rodríguez-Calvillo, M.2    Inogés, S.3
  • 34
    • 77955780508 scopus 로고    scopus 로고
    • Optimizing dendritic cell-based immunotherapy in multiple myeloma: intranodal injections of idiotype-pulsed CD40 ligand-matured vaccines led to induction of type-1 and cytotoxic T-cell immune responses in patients
    • Yi Q, Szmania S, Freeman J, et al. Optimizing dendritic cell-based immunotherapy in multiple myeloma: intranodal injections of idiotype-pulsed CD40 ligand-matured vaccines led to induction of type-1 and cytotoxic T-cell immune responses in patients. Br J Haematol 2010;150:554-64.
    • (2010) Br J Haematol. , vol.150 , pp. 554-564
    • Yi, Q.1    Szmania, S.2    Freeman, J.3
  • 35
    • 78650644121 scopus 로고    scopus 로고
    • Induction of cellular immune responses in patients with stage-I multiple myeloma after vaccination with autologous idiotype-pulsed dendritic cells
    • Röllig C, Schmidt C, Bornhäuser M, Ehninger G, Schmitz M, Auffermann-Gretzinger S. Induction of cellular immune responses in patients with stage-I multiple myeloma after vaccination with autologous idiotype-pulsed dendritic cells. J Immunother 2011;34:100-6.
    • (2011) J Immunother , vol.34 , pp. 100-106
    • Röllig, C.1    Schmidt, C.2    Bornhäuser, M.3    Ehninger, G.4    Schmitz, M.5    Auffermann-gretzinger, S.6
  • 36
    • 0035884392 scopus 로고    scopus 로고
    • The epithelial tumor antigen MUC1 is expressed in hematological malignancies and is recognized by MUC1-specific cytotoxic T-lymphocytes
    • Brossart P, Schneider A, Dill P, et al. The epithelial tumor antigen MUC1 is expressed in hematological malignancies and is recognized by MUC1-specific cytotoxic T-lymphocytes. Cancer Res 2001;61:6846-50.
    • (2001) Cancer Res. , vol.61 , pp. 6846-6850
    • Brossart, P.1    Schneider, A.2    Dill, P.3
  • 37
    • 0037305571 scopus 로고    scopus 로고
    • Induction of myeloma-specific cytotoxic T cells using dendritic cells transfected with tumor-derived RNA
    • Milazzo C, Reichardt VL, Müller MR, Grünebach F, Brossart P. Induction of myeloma-specific cytotoxic T cells using dendritic cells transfected with tumor-derived RNA. Blood 2003;101:977-
    • (2003) Blood , vol.101 , pp. 977-982
    • Milazzo, C.1    Reichardt, V.L.2    Müller, M.R.3    Grünebach, F.4    Brossart, P.5
  • 38
    • 33750461287 scopus 로고    scopus 로고
    • NY-ESO-1 immunotherapy for multiple myeloma
    • Szmania S, Tricot G, van Rhee F. NY-ESO-1 immunotherapy for multiple myeloma. Leuk Lymphoma 2006;47:2037-48.
    • (2006) Leuk Lymphoma. , vol.47 , pp. 2037-2048
    • Szmania, S.1    Tricot, G.2    Rhee, F.V.3
  • 39
    • 27544514423 scopus 로고    scopus 로고
    • Protein transduction of dendritic cells for NY-ESO-1-based immunotherapy of myeloma
    • Batchu RB, Moreno AM, Szmania SM, et al. Protein transduction of dendritic cells for NY-ESO-1-based immunotherapy of myeloma. Cancer Res 2005;65:10041-9.
    • (2005) Cancer Res. , vol.65 , pp. 10041-10049
    • Batchu, R.B.1    Moreno, A.M.2    Szmania, S.M.3
  • 40
    • 0036683378 scopus 로고    scopus 로고
    • Sperm protein 17 (Sp17) is a suitable target for immunotherapy of multiple myeloma
    • Chiriva-Internati M, Wang Z, Salati E, Bumm K, Barlogie B, Lim SH. Sperm protein 17 (Sp17) is a suitable target for immunotherapy of multiple myeloma. Blood 2002;100:961-5.
    • (2002) Blood , vol.100 , pp. 961-965
    • Chiriva-internati, M.1    Wang, Z.2    Salati, E.3    Bumm, K.4    Barlogie, B.5    Lim, S.H.6
  • 41
    • 0033151591 scopus 로고    scopus 로고
    • The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes
    • Vonderheide RH, Hahn WC, Schultze JL, Nadler LM. The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes. Immunity 1999;10:673-9.
    • (1999) Immunity , vol.10 , pp. 673-679
    • Vonderheide, R.H.1    Hahn, W.C.2    Schultze, J.L.3    Nadler, L.M.4
  • 42
    • 79952114103 scopus 로고    scopus 로고
    • Generation of myeloma-specific T cells using dendritic cells loaded with MUC1- and hTERT- drived nonapeptides or myeloma cell apoptotic bodies
    • Ocadlikova D, Kryukov F, Mollova K, et al. Generation of myeloma-specific T cells using dendritic cells loaded with MUC1- and hTERT- drived nonapeptides or myeloma cell apoptotic bodies. Neoplasma 2010;57:455-64.
    • (2010) Neoplasma , vol.57 , pp. 455-464
    • Ocadlikova, D.1    Kryukov, F.2    Mollova, K.3
  • 43
    • 34548828781 scopus 로고    scopus 로고
    • Dickkopf-1 (DKK1) is a widely expressed and potent tumor-associated antigen in multiple myeloma
    • Qian J, Xie J, Hong S, et al. Dickkopf-1 (DKK1) is a widely expressed and potent tumor-associated antigen in multiple myeloma. Blood 2007;110:1587-94.
    • (2007) Blood , vol.110 , pp. 1587-1594
    • Qian, J.1    Xie, J.2    Hong, S.3
  • 44
    • 35148833846 scopus 로고    scopus 로고
    • Induction of multiple myeloma-specific cytotoxic T lymphocyte stimulation by dendritic cell pulsing with purified and optimized myeloma cell lysates
    • Lee JJ, Choi BH, Kang HK, et al. Induction of multiple myeloma-specific cytotoxic T lymphocyte stimulation by dendritic cell pulsing with purified and optimized myeloma cell lysates. Leuk Lymphoma 2007;48:2022-31.
    • (2007) Leuk Lymphoma , vol.48 , pp. 2022-2031
    • Lee, J.J.1    Choi, B.H.2    Kang, H.K.3
  • 45
    • 0036565872 scopus 로고    scopus 로고
    • Tumor lysate-specific cytotoxic T lymphocytes in multiple myeloma: promising effector cells for immunotherapy
    • Wen YJ, Min R, Tricot G, Barlogie B, Yi Q. Tumor lysate-specific cytotoxic T lymphocytes in multiple myeloma: promising effector cells for immunotherapy. Blood 2002;99:3280-5.
    • (2002) Blood , vol.99 , pp. 3280-3285
    • Wen, Y.J.1    Min, R.2    Tricot, G.3    Barlogie, B.4    Yi, Q.5
  • 46
    • 77954670210 scopus 로고    scopus 로고
    • Alpha-type 1-polarized dendritic cells loaded with apoptotic allogeneic myeloma cell line induce strong CTL responses against autologous myeloma cells
    • Yang DH, Kim MH, Hong CY, et al. Alpha-type 1-polarized dendritic cells loaded with apoptotic allogeneic myeloma cell line induce strong CTL responses against autologous myeloma cells. Ann Hematol 2010;89:795-801.
    • (2010) Ann Hematol. , vol.89 , pp. 795-801
    • Yang, D.H.1    Kim, M.H.2    Hong, C.Y.3
  • 47
    • 84355166808 scopus 로고    scopus 로고
    • Successful cross-presentation of allogeneic myeloma cells by autologous alpha-type 1-polarized dendritic cells as an effective tumor antigen in myeloma patients with matched monoclonal immunoglobulins
    • Yang DH, Kim MH, Lee YK, et al. Successful cross-presentation of allogeneic myeloma cells by autologous alpha-type 1-polarized dendritic cells as an effective tumor antigen in myeloma patients with matched monoclonal immunoglobulins. Ann Hematol 2011;90:1419-26.
    • (2011) Ann Hematol. , vol.90 , pp. 1419-1426
    • Yang, D.H.1    Kim, M.H.2    Lee, Y.K.3
  • 48
    • 29344469779 scopus 로고    scopus 로고
    • Targeting heat shock proteins for immunotherapy in multiple myeloma: generation of myelomaspecific CTLs using dendritic cells pulsed with tumor-derived gp96
    • Qian J, Wang S, Yang J, et al. Targeting heat shock proteins for immunotherapy in multiple myeloma: generation of myelomaspecific CTLs using dendritic cells pulsed with tumor-derived gp96. Clin Cancer Res 2005;11:8808-15.
    • (2005) Clin Cancer Res. , vol.11 , pp. 8808-8815
    • Qian, J.1    Wang, S.2    Yang, J.3
  • 49
    • 70449719118 scopus 로고    scopus 로고
    • Myeloma cell line-derived, pooled heat shock proteins as a universal vaccine for immunotherapy of multiple myeloma
    • Qian J, Hong S, Wang S, et al. Myeloma cell line-derived, pooled heat shock proteins as a universal vaccine for immunotherapy of multiple myeloma. Blood 2009;114:3880-9.
    • (2009) Blood , vol.114 , pp. 3880-3889
    • Qian, J.1    Hong, S.2    Wang, S.3
  • 50
    • 12744278406 scopus 로고    scopus 로고
    • Enhanced antitumor immunity derived from a novel vaccine of fusion hybrid between dendritic and engineered myeloma cells
    • Hao S, Bi X, Xu S, et al. Enhanced antitumor immunity derived from a novel vaccine of fusion hybrid between dendritic and engineered myeloma cells. Exp Oncol 2004;26:300-6.
    • (2004) Exp Oncol. , vol.26 , pp. 300-306
    • Hao, S.1    Bi, X.2    Xu, S.3
  • 51
    • 20444495703 scopus 로고    scopus 로고
    • Fusion of dendritic cells with multiple myeloma cells results in maturation and enhanced antigen presentation
    • Vasir B, Borges V, Wu Z, et al. Fusion of dendritic cells with multiple myeloma cells results in maturation and enhanced antigen presentation. Br J Haematol 2005;129:687-700.
    • (2005) Br J Haematol. , vol.129 , pp. 687-700
    • Vasir, B.1    Borges, V.2    Wu, Z.3
  • 52
    • 0042738871 scopus 로고    scopus 로고
    • Ex vivo induction of multiple myeloma-specific cytotoxic T lymphocytes
    • Hayashi T, Hideshima T, Akiyama M, et al. Ex vivo induction of multiple myeloma-specific cytotoxic T lymphocytes. Blood 2003;102:1435-42.
    • (2003) Blood , vol.102 , pp. 1435-1442
    • Hayashi, T.1    Hideshima, T.2    Akiyama, M.3
  • 53
    • 78751510278 scopus 로고    scopus 로고
    • Vaccination with dendritic cell/tumor fusion cells results in cellular and humoral antitumor immune responses in patients with multiple myeloma
    • Rosenblatt J, Vasir B, Uhl L, et al. Vaccination with dendritic cell/tumor fusion cells results in cellular and humoral antitumor immune responses in patients with multiple myeloma. Blood 2011;117:393-402.
    • (2011) Blood , vol.117 , pp. 393-402
    • Rosenblatt, J.1    Vasir, B.2    Uhl, L.3
  • 54
    • 73349121252 scopus 로고    scopus 로고
    • Idiotype-pulsed antigen-presenting cells following autologous transplantation for multiple myeloma may be associated with prolonged survival
    • Lacy MQ, Mandrekar S, Dispenzieri A, et al. Idiotype-pulsed antigen-presenting cells following autologous transplantation for multiple myeloma may be associated with prolonged survival. Am J Hematol 2009;84:799-802.
    • (2009) Am J Hematol. , vol.84 , pp. 799-802
    • Lacy, M.Q.1    Mandrekar, S.2    Dispenzieri, A.3
  • 55
    • 0030026776 scopus 로고    scopus 로고
    • Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells
    • Hsu FJ, Benike C, Fagnoni F, et al. Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nat Med 1996;2:52-8.
    • (1996) Nat Med. , vol.2 , pp. 52-58
    • Hsu, F.J.1    Benike, C.2    Fagnoni, F.3
  • 56
    • 0031941423 scopus 로고    scopus 로고
    • Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells
    • Nestle FO, Alijagic S, Gilliet M, et al. Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nat Med 1998;4:328-32.
    • (1998) Nat Med. , vol.4 , pp. 328-332
    • Nestle, F.O.1    Alijagic, S.2    Gilliet, M.3
  • 57
    • 79951871014 scopus 로고    scopus 로고
    • Sipuleucel-T: harbinger of a new age of therapeutics for prostate cancer
    • Madan RA, Gulley JL. Sipuleucel-T: harbinger of a new age of therapeutics for prostate cancer. Expert Rev Vaccines 2011;10: 141-50.
    • (2011) Expert Rev Vaccines , vol.10 , pp. 141-150
    • Madan, R.A.1    Gulley, J.L.2
  • 58
    • 2642631750 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions
    • Jonuleit H, Kühn U, Müller G, et al. Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions. Eur J Immunol 1997;27:3135-42.
    • (1997) Eur J Immunol. , vol.27 , pp. 3135-3142
    • Jonuleit, H.1    Kühn, U.2    Müller, G.3
  • 59
    • 0035383783 scopus 로고    scopus 로고
    • Prostaglandin E(2) is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer
    • Kalinski P, Vieira PL, Schuitemaker JH, de Jong EC, Kapsenberg ML. Prostaglandin E(2) is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer. Blood 2001;97:3466-9.
    • (2001) Blood , vol.97 , pp. 3466-3469
    • Kalinski, P.1    Vieira, P.L.2    Schuitemaker, J.H.3    Jong, E.C.D.4    Kapsenberg, M.L.5
  • 60
    • 33746328653 scopus 로고    scopus 로고
    • Dendritic cells expand antigen-specific Foxp3+ CD25+ CD4+ regulatory T cells including suppressors of alloreactivity
    • Yamazaki S, Inaba K, Tarbell KV, Steinman RM. Dendritic cells expand antigen-specific Foxp3+ CD25+ CD4+ regulatory T cells including suppressors of alloreactivity. Immunol Rev 2006;212: 314-29.
    • (2006) Immunol Rev. , vol.212 , pp. 314-329
    • Yamazaki, S.1    Inaba, K.2    Tarbell, K.V.3    Steinman, R.M.4
  • 61
    • 10744224631 scopus 로고    scopus 로고
    • Maturation of dendritic cells is a prerequisite for inducing immune responses in advanced melanoma patients
    • de Vries IJ, Lesterhuis WJ, Scharenborg NM, et al. Maturation of dendritic cells is a prerequisite for inducing immune responses in advanced melanoma patients. Clin Cancer Res 2003;9:5091-100.
    • (2003) Clin Cancer Res. , vol.9 , pp. 5091-5100
    • Vries, I.J.D.1    Lesterhuis, W.J.2    Scharenborg, N.M.3
  • 62
    • 10844227526 scopus 로고    scopus 로고
    • Immunological properties and vaccine efficacy of murine dendritic cells simultaneously expressing melanoma-associated antigen and interleukin-12
    • Okada N, Iiyama S, Okada Y, et al. Immunological properties and vaccine efficacy of murine dendritic cells simultaneously expressing melanoma-associated antigen and interleukin-12. Cancer Gene Ther 2005;12:72-83.
    • (2005) Cancer Gene Ther. , vol.12 , pp. 72-83
    • Okada, N.1    Iiyama, S.2    Okada, Y.3
  • 63
    • 4344596051 scopus 로고    scopus 로고
    • Alpha-type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity
    • Mailliard RB, Wankowicz-Kalinska A, Cai Q, et al. Alpha-type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity. Cancer Res 2004;64:5934-7.
    • (2004) Cancer Res. , vol.64 , pp. 5934-5937
    • Mailliard, R.B.1    Wankowicz-kalinska, A.2    Cai, Q.3
  • 64
    • 46949095104 scopus 로고    scopus 로고
    • Type 1-polarized dendritic cells loaded with autologous tumor are a potent immunogen against chronic lymphocytic leukemia
    • Lee JJ, Foon KA, Mailliard RB, Muthuswamy R, Kalinski P. Type 1-polarized dendritic cells loaded with autologous tumor are a potent immunogen against chronic lymphocytic leukemia. J Leukoc Biol 2008;84:319-25.
    • (2008) J Leukoc Biol. , vol.84 , pp. 319-325
    • Lee, J.J.1    Foon, K.A.2    Mailliard, R.B.3    Muthuswamy, R.4    Kalinski, P.5
  • 65
    • 33846013255 scopus 로고    scopus 로고
    • Polarized type-1 dendritic cells (DC1) producing high levels of IL-12 family members rescue patient TH1-type antimelanoma CD4+ T cell responses in vitro
    • Wesa A, Kalinski P, Kirkwood JM, Tatsumi T, Storkus WJ. Polarized type-1 dendritic cells (DC1) producing high levels of IL-12 family members rescue patient TH1-type antimelanoma CD4+ T cell responses in vitro. J Immunother 2007;30:75-82.
    • (2007) J Immunother , vol.30 , pp. 75-82
    • Wesa, A.1    Kalinski, P.2    Kirkwood, J.M.3    Tatsumi, T.4    Storkus, W.J.5
  • 66
    • 67349254467 scopus 로고    scopus 로고
    • Type-1 polarized dendritic cells primed for high IL-12 production show enhanced activity as cancer vaccines
    • Giermasz AS, Urban JA, Nakamura Y, et al. Type-1 polarized dendritic cells primed for high IL-12 production show enhanced activity as cancer vaccines. Cancer Immunol Immunother 2009; 58:1329-36.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 1329-1336
    • Giermasz, A.S.1    Urban, J.A.2    Nakamura, Y.3
  • 67
    • 79951978155 scopus 로고    scopus 로고
    • Induction of CD8+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {alpha}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in patients with recurrent malignant glioma
    • Okada H, Kalinski P, Ueda R, et al. Induction of CD8+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {alpha}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in patients with recurrent malignant glioma. J Clin Oncol 2011;29:330-6.
    • (2011) J Clin Oncol. , vol.29 , pp. 330-336
    • Okada, H.1    Kalinski, P.2    Ueda, R.3
  • 69
    • 0042931206 scopus 로고    scopus 로고
    • Dendritic cells mediate NK cell help for Th1 and CTL responses: two-signal requirement for the induction of NK cell helper function
    • Mailliard RB, Son YI, Redlinger R, et al. Dendritic cells mediate NK cell help for Th1 and CTL responses: two-signal requirement for the induction of NK cell helper function. J Immunol 2003;171:2366-73.
    • (2003) J Immunol. , vol.171 , pp. 2366-2373
    • Mailliard, R.B.1    Son, Y.I.2    Redlinger, R.3
  • 70
    • 77954708184 scopus 로고    scopus 로고
    • Enhancement of antitumor effect using dendritic cells activated with natural killer cells in the presence of Toll-like receptor agonist
    • Pham TN, Hong CY, Min JJ, et al. Enhancement of antitumor effect using dendritic cells activated with natural killer cells in the presence of Toll-like receptor agonist. Exp Mol Med 2010;42: 407-19.
    • (2010) Exp Mol Med. , vol.42 , pp. 407-419
    • Pham, T.N.1    Hong, C.Y.2    Min, J.J.3
  • 71
    • 80051475297 scopus 로고    scopus 로고
    • Induction of myeloma-specific cytotoxic T lymphocytes responses by natural killer cells stimulated-dendritic cells in patients with multiple myeloma
    • Nguyen-Pham TN, Im CM, Nguyen TA, et al. Induction of myeloma-specific cytotoxic T lymphocytes responses by natural killer cells stimulated-dendritic cells in patients with multiple myeloma. Leuk Res 2011;35:1241-7.
    • (2011) Leuk Res. , vol.35 , pp. 1241-1247
    • Nguyen-pham, T.N.1    Im, C.M.2    Nguyen, T.A.3
  • 72
    • 23944489407 scopus 로고    scopus 로고
    • Selected toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
    • Napolitani G, Rinaldi A, Bertoni F, Sallusto F, Lanzavecchia A. Selected toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat Immunol 2005;6:769-76.
    • (2005) Nat Immunol. , vol.6 , pp. 769-776
    • Napolitani, G.1    Rinaldi, A.2    Bertoni, F.3    Sallusto, F.4    Lanzavecchia, A.5
  • 73
    • 33644777565 scopus 로고    scopus 로고
    • CD38 orchestrates migration, survival, and Th1 immune response of human mature dendritic cells
    • Frasca L, Fedele G, Deaglio S, et al. CD38 orchestrates migration, survival, and Th1 immune response of human mature dendritic cells. Blood 2006;107:2392-9.
    • (2006) Blood , vol.107 , pp. 2392-2399
    • Frasca, L.1    Fedele, G.2    Deaglio, S.3
  • 74
    • 58149247727 scopus 로고    scopus 로고
    • Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain
    • Faure-André G, Vargas P, Yuseff MI, et al. Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain. Science 2008;322:1705-10.
    • (2008) Science , vol.322 , pp. 1705-1710
    • Faure-andré, G.1    Vargas, P.2    Yuseff, M.I.3
  • 75
    • 79960067341 scopus 로고    scopus 로고
    • Type I and II interferons enhance dendritic cell maturation and migration capacity by regulating CD38 and CD74 that have synergistic effects with TLR agonists
    • Nguyen-Pham TN, Lim MS, Nguyen TA, et al. Type I and II interferons enhance dendritic cell maturation and migration capacity by regulating CD38 and CD74 that have synergistic effects with TLR agonists. Cell Mol Immunol 2011;8:341-7.
    • (2011) Cell Mol Immunol. , vol.8 , pp. 341-347
    • Nguyen-pham, T.N.1    Lim, M.S.2    Nguyen, T.A.3
  • 76
    • 77955282458 scopus 로고    scopus 로고
    • Ursolic acid isolated from Uncaria rhynchophylla activates human dendritic cells via TLR2 and/or TLR4 and induces the production of IFN-gamma by CD4+ naive T cells
    • Jung TY, Pham TN, Umeyama A, et al. Ursolic acid isolated from Uncaria rhynchophylla activates human dendritic cells via TLR2 and/or TLR4 and induces the production of IFN-gamma by CD4+ naive T cells. Eur J Pharmacol 2010;643:297-303.
    • (2010) Eur J Pharmacol. , vol.643 , pp. 297-303
    • Jung, T.Y.1    Pham, T.N.2    Umeyama, A.3
  • 77
    • 77958460504 scopus 로고    scopus 로고
    • Uncarinic acid C plus IFN-γ generates monocyte-derived dendritic cells and induces a potent Th1 polarization with capacity to migrate
    • Bae WK, Umeyama A, Chung IJ, Lee JJ, Takei M. Uncarinic acid C plus IFN-γ generates monocyte-derived dendritic cells and induces a potent Th1 polarization with capacity to migrate. Cell Immunol 2010;266:104-10.
    • (2010) Cell Immunol. , vol.266 , pp. 104-110
    • Bae, W.K.1    Umeyama, A.2    Chung, I.J.3    Lee, J.J.4    Takei, M.5
  • 78
    • 0036884424 scopus 로고    scopus 로고
    • A blast from the past: clearance of apoptotic cells regulates immune responses
    • Savill J, Dransfield I, Gregory C, Haslett C. A blast from the past: clearance of apoptotic cells regulates immune responses. Nat Rev Immunol 2002;2:965-75.
    • (2002) Nat Rev Immunol. , vol.2 , pp. 965-975
    • Savill, J.1    Dransfield, I.2    Gregory, C.3    Haslett, C.4
  • 79
    • 27744449724 scopus 로고    scopus 로고
    • IL-6-STAT3 controls intracellular MHC class II alphabeta dimer level through cathepsin S activity in dendritic cells
    • Kitamura H, Kamon H, Sawa S, et al. IL-6-STAT3 controls intracellular MHC class II alphabeta dimer level through cathepsin S activity in dendritic cells. Immunity 2005;23:491-502.
    • (2005) Immunity , vol.23 , pp. 491-502
    • Kitamura, H.1    Kamon, H.2    Sawa, S.3
  • 80
    • 33847368558 scopus 로고    scopus 로고
    • Targeting of Jak/STAT pathway in antigen presenting cells in cancer
    • Nefedova Y, Gabrilovich DI. Targeting of Jak/STAT pathway in antigen presenting cells in cancer. Curr Cancer Drug Targets 2007;7:71-7.
    • (2007) Curr Cancer Drug Targets , vol.7 , pp. 71-77
    • Nefedova, Y.1    Gabrilovich, D.I.2
  • 81
    • 33845482670 scopus 로고    scopus 로고
    • Optimizing immunotherapy in multiple myeloma: Restoring the function of patients' monocytederived dendritic cells by inhibiting p38 or activating MEK/ERK MAPK and neutralizing interleukin-6 in progenitor cells
    • Wang S, Hong S, Yang J, et al. Optimizing immunotherapy in multiple myeloma: Restoring the function of patients' monocytederived dendritic cells by inhibiting p38 or activating MEK/ERK MAPK and neutralizing interleukin-6 in progenitor cells. Blood 2006;108:4071-7.
    • (2006) Blood , vol.108 , pp. 4071-4077
    • Wang, S.1    Hong, S.2    Yang, J.3
  • 82
    • 61649125595 scopus 로고    scopus 로고
    • The dysfunction and abnormal signaling pathway of dendritic cells loaded by tumor antigen can be overcome by neutralizing VEGF in multiple myeloma
    • Yang DH, Park JS, Jin CJ, et al. The dysfunction and abnormal signaling pathway of dendritic cells loaded by tumor antigen can be overcome by neutralizing VEGF in multiple myeloma. Leuk Res 2009;33:665-70.
    • (2009) Leuk Res. , vol.33 , pp. 665-670
    • Yang, D.H.1    Park, J.S.2    Jin, C.J.3
  • 83
    • 0037103366 scopus 로고    scopus 로고
    • Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells
    • Scandella E, Men Y, Gillessen S, Förster R, Groettrup M. Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells. Blood 2002;100: 1354-61.
    • (2002) Blood , vol.100 , pp. 1354-1561
    • Scandella, E.1    Men, Y.2    Gillessen, S.3    Förster, R.4    Groettrup, M.5
  • 84
    • 48649095924 scopus 로고    scopus 로고
    • Ability of mature dendritic cells to interact with regulatory T cells is imprinted during maturation
    • Muthuswamy R, Urban J, Lee JJ, Reinhart TA, Bartlett D, Kalinski P. Ability of mature dendritic cells to interact with regulatory T cells is imprinted during maturation. Cancer Res 2008;68:5972-8.
    • (2008) Cancer Res. , vol.68 , pp. 5972-5978
    • Muthuswamy, R.1    Urban, J.2    Lee, J.J.3    Reinhart, T.A.4    Bartlett, D.5    Kalinski, P.6
  • 85
    • 34447639113 scopus 로고    scopus 로고
    • Single administration of low dose cyclophosphamide augments the antitumor effect of dendritic cell vaccine
    • Liu JY, Wu Y, Zhang XS, et al. Single administration of low dose cyclophosphamide augments the antitumor effect of dendritic cell vaccine. Cancer Immunol Immunother 2007;56:1597-604.
    • (2007) Cancer Immunol Immunother , vol.56 , pp. 1597-1604
    • Liu, J.Y.1    Wu, Y.2    Zhang, X.S.3
  • 86
    • 21244505782 scopus 로고    scopus 로고
    • Allogeneic dendritic cell vaccination against metastatic renal cell carcinoma with or without cyclophosphamide
    • Höltl L, Ramoner R, Zelle-Rieser C, et al. Allogeneic dendritic cell vaccination against metastatic renal cell carcinoma with or without cyclophosphamide. Cancer Immunol Immunother 2005;54:663-70.
    • (2005) Cancer Immunol Immunother , vol.54 , pp. 663-670
    • Höltl, L.1    Ramoner, R.2    Zelle-rieser, C.3
  • 87
    • 67349107194 scopus 로고    scopus 로고
    • The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells
    • Galustian C, Meyer B, Labarthe MC, et al. The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells. Cancer Immunol Immunother 2009;58:1033-45.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 1033-1045
    • Galustian, C.1    Meyer, B.2    Labarthe, M.C.3
  • 88
    • 70349153856 scopus 로고    scopus 로고
    • Immune dysfunction in chronic lymphocytic leukemia T cells and lenalidomide as an immunomodulatory drug
    • Ramsay AG, Gribben JG. Immune dysfunction in chronic lymphocytic leukemia T cells and lenalidomide as an immunomodulatory drug. Haematologica 2009;94:1198-202.
    • (2009) Haematologica , vol.94 , pp. 1198-1202
    • Ramsay, A.G.1    Gribben, J.G.2
  • 89
    • 0032731377 scopus 로고    scopus 로고
    • Generation of anti-idiotype immune responses following vaccination with idiotype-protein pulsed dendritic cells in myeloma
    • Cull G, Durrant L, Stainer C, Haynes A, Russell N. Generation of anti-idiotype immune responses following vaccination with idiotype-protein pulsed dendritic cells in myeloma. Br J Haematol 1999;107:648-55.
    • (1999) Br J Haematol , vol.107 , pp. 648-655
    • Cull, G.1    Durrant, L.2    Stainer, C.3    Haynes, A.4    Russell, N.5


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