Platycodin D, a triterpenoid sapoinin from Platycodon grandiflorum, ameliorates cisplatin-induced nephrotoxicity in mice

Food and Chemical Toxicology

Volumn 50, Issue 12, 2012, Pages 4254-4259

  Kim, Tae Won ^a   Song, In Bae ^a   Lee, Hong Ki ^a   Lim, Jong Hwan ^b   Cho, Eun Sang ^a   Son, Hwa Young ^a   Park, Sang Jin ^b   Kim, Jong Woo ^b   Yun, Hyo In ^a  

^a Chungnam National University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Cisplatin; Nephrotoxicity; Platycodin D; Platycodon grandiflorum

Indexed keywords

CISPLATIN; CREATININE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; NITRIC OXIDE; PLATYCODIN; SAPONIN; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DESQUAMATION; EPITHELIUM CELL; GENE OVEREXPRESSION; HISTOPATHOLOGY; LIPID PEROXIDATION; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; PLANT ROOT; PLATYCODON; UREA NITROGEN BLOOD LEVEL; URINARY CAST;

ANIMALS; APOPTOSIS; BLOOD UREA NITROGEN; CISPLATIN; CREATININE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; KIDNEY; KIDNEY DISEASES; LIPID PEROXIDATION; MALE; MICE; MICE, INBRED ICR; NF-KAPPA B; NITRIC OXIDE; OXIDATIVE STRESS; PLANT ROOTS; PLATYCODON; SAPONINS; SUPEROXIDE DISMUTASE; TRITERPENES;

CAMPANULACEAE; MUS; PLATYCODON GRANDIFLORUM;

EID: 84866872485     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.05.022     Document Type: Article

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