HPLC analysis of saponins in platycodi radix

Korean Journal of Pharmacognosy

Volumn 38, Issue 2, 2007, Pages 192-196

  Hyun, Ki Kim ^a   Jae, Seok Choi ^a   Dae, Seok Yoo ^a   Yeon, Hee Choi ^a   Gyu, Hwan Yon ^a   Kyung, Sik Hong ^a   Byung, Hoe Lee ^a   Hye, Jin Kim ^a   Eun, Ju Kim ^b   Byoung, Keun Park ^b   Young, Chul Jeong ^c   Young, Sup Kim ^a   Shi, Yong Ryu ^a  

^a Korea Research Institute of Chemical Technology   (South Korea)

^b JangSaeng Doraji Co Ltd   (South Korea)

^c Jinju International University   (South Korea)

Author keywords

Campanulaceae; HPLC; Platycodon grandiflorum; Quantitative analysis; Saponin

Indexed keywords

EID: 76749136716     PISSN: 02533073     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Kim, Y.P., Lee, E. B., Kim, S. Y., Li, D., Ban, H. S., Lim, S. S., Shin, K. H. and Ohuchi, K. (2001) Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum. Planta Med. 67: 362-364.
2. Shin, C. Y., Lee, W. J., Lee, E. B., Choi, E. Y. and Ko, K. H. (2002) Platycodin D and D3 increase airway mucin release in vivo and in vitro in rats and hamsters. Planta Med. 68: 221-225.
3. Lee, K.J. and Jeong, H.G. (2002) Protective effect of Platycodi Radix on carbon tetrachloride-induced hepatotoxicity. Food Chem. Toxicol., 40: 517-525.
4. Lee, K.J., You, H.J., Park, S.J., Kim, Y.S., Chung, Y.C., Jeong, T.C. and Jeong, H.G.(2001) Hepatoprotective effects of Platycodon grandiflorum on acetaminophen -induced liver damage in mice. Cancer Lett., 174: 73-81.
5. Choi, C.Y., Kim, J.Y, Kim, Y.S., Chung, Y.C., Seo, J.K. and Jeong, H.G. (2001) Aqueous extract isolated from Platycodon grandiflorumelicits the release of nitric oxide and tumor necrosis factor-a from murine macrophages. International Immunopharmacology, 1: 1141-1151.
6. Choi, C.Y., Kim, J.Y., Kim, Y.S., Chung, Y.C., Hahm, K.S. and Jeong, H.G. (2001) Augmentation of macrophage functions by an aqueous extract isolated from Platycodon grandiflorum. Cancer Lett., 166: 17-25.
7. Saeki T, Koide K and Nikaide T (1999) A comparative study on commercial, botanical gardens and wild samples of the roots of Platycodon grandiflorum by HPLC analysis. Planta Med. 65: 428-431.
8. Kim, G.S., Kim, H.T., Seong. J.D., Park, H.S., Kim, S.D.(2002) Quantitative analysis of platycodin d from Platycodon grandiflorum by HPLC-ELSD. Korean J. Medicinal Crop Sci. 10: 200-205.
9. Kim, Y.S., Kim, J.S., Choi, S.U., Kim, J.S., Lee, H.S., Roh, S.H., Jeong, Y.C., Kim, Y.K. and Ryu, S.Y.(2005) Isolation of a new saponin and cytotoxic effect of saponins from the root of Platycodon grandiflorum on human tumor cell lines. Planta Med. 71: 566-568.