Inhibition of γ-glutamyl transpeptidase or cysteine sconjugate β-lyase activity blocks the nephrotoxicity of cisplatin in mice

Journal of Pharmacology and Experimental Therapeutics

Volumn 300, Issue 1, 2002, Pages 142-148

  Townsend, Danyelle M ^a   Hanigan, Marie H ^b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIVICIN; AMINOOXYACETIC ACID; CISPLATIN; CYSTEINE CONJUGATE BETA LYASE; GAMMA GLUTAMYLTRANSFERASE; PLATINUM; SODIUM CHLORIDE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME INHIBITION; HISTOLOGY; KIDNEY PROXIMAL TUBULE; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; UREA NITROGEN BLOOD LEVEL; WEIGHT REDUCTION;

AMINOOXYACETIC ACID; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; BLOOD UREA NITROGEN; BODY WEIGHT; CARBON-SULFUR LYASES; CISPLATIN; ENZYME INHIBITORS; GAMMA-GLUTAMYLTRANSFERASE; ISOXAZOLES; KIDNEY; KIDNEY DISEASES; MALE; MICE; MICE, INBRED C57BL; PLATINUM; SURVIVAL ANALYSIS;

EID: 0036139415     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.300.1.142     Document Type: Article

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