메뉴 건너뛰기




Volumn 3, Issue APR, 2012, Pages

The emerging role of microRNAs in schizophrenia and autism spectrum disorders

Author keywords

Autism; Microrna; Neuropsychiatric disorder; Schizophrenia; Synaptic plasticity

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CELL PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; METHYL CPG BINDING PROTEIN 2; MICRORNA 128; MICRORNA 134; MICRORNA 137; MICRORNA 138; MICRORNA 181B; MICRORNA 195; MICRORNA 21; MICRORNA 212; MICRORNA 219; MICRORNA 23A; MICRORNA 30A; MICRORNA 30D; MICRORNA 346; MICRORNA 34A; MICRORNA 381; MICRORNA 495; MIND BOMB 1 PROTEIN; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; PROTEIN KINASE B; UNCLASSIFIED DRUG;

EID: 84866866864     PISSN: None     EISSN: 16640640     Source Type: Journal    
DOI: 10.3389/fpsyt.2012.00039     Document Type: Review
Times cited : (105)

References (109)
  • 3
    • 84857006612 scopus 로고    scopus 로고
    • Epigenetics of schizophrenia
    • Akbarian, S. (2010). Epigenetics of schizophrenia. Curr. Top. Behav. Neurosci. 4, 611-628.
    • (2010) Curr. Top. Behav. Neurosci. , vol.4 , pp. 611-628
    • Akbarian, S.1
  • 4
    • 0028948389 scopus 로고
    • Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of Schizo phrenics
    • Akbarian, S., Kim, J. J., Potkin, S. G., Hagman, J. O., Tafazzoli, A., Bunney, W. E. Jr., and Jones, E G. (1995). Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of Schizo phrenics. Arch. Gen. Psychiatry 52, 258-266.
    • (1995) Arch. Gen. Psychiatry , vol.52 , pp. 258-266
    • Akbarian, S.1    Kim, J.J.2    Potkin, S.G.3    Hagman, J.O.4    Tafazzoli, A.5    Bunney Jr., W.E.6    Jones, E.G.7
  • 5
    • 79961173182 scopus 로고    scopus 로고
    • Direct repro-gramming of adult human fibrob-lasts to functional neurons under defined conditions
    • Ambasudhan, R., Talantova, M., Coleman, R.,Yuan, X.,Zhu, S., Lipton, S. A., and Ding, S. (2011). Direct repro-gramming of adult human fibrob-lasts to functional neurons under defined conditions. Cell Stem Cell 9, 113-118.
    • (2011) Cell Stem Cell , vol.9 , pp. 113-118
    • Ambasudhan, R.1    Talantova, M.2    Coleman, R.3    Yuan, X.4    Zhu, S.5    Lipton, S.A.6    Ding, S.7
  • 6
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, andfunction
    • Bartel, D. P. (2004). MicroRNAs: genomics, biogenesis, mechanism, andfunction. Cell 116,281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 7
    • 78650238139 scopus 로고    scopus 로고
    • Schizophrenia is associated with an increase in cortical microRNA biogenesis
    • Beveridge, N. J., Gardiner, E., Carroll, A. P., Tooney, P. A., and Cairns, M. J. (2010). Schizophrenia is associated with an increase in cortical microRNA biogenesis. Mol. Psychiatry 15, 1176-1189.
    • (2010) Mol. Psychiatry , vol.15 , pp. 1176-1189
    • Beveridge, N.J.1    Gardiner, E.2    Carroll, A.P.3    Tooney, P.A.4    Cairns, M.J.5
  • 9
    • 85027951676 scopus 로고    scopus 로고
    • Functions of noncoding RNAs in neural development and neurological diseases
    • Bian, S., and Sun, T. (2011). Functions of noncoding RNAs in neural development and neurological diseases. Mol. Neurobiol. 44, 359-373.
    • (2011) Mol. Neurobiol. , vol.44 , pp. 359-373
    • Bian, S.1    Sun, T.2
  • 12
    • 63649138643 scopus 로고    scopus 로고
    • miR-124 regulates adult neurogenesis in the sub-ventricular zone stem cell niche
    • Cheng, L. C., Pastrana, E., Tavazoie, M., andDoetsch, E (2009). miR-124 regulates adult neurogenesis in the sub-ventricular zone stem cell niche. Nat. Neurosci. 12, 399-408.
    • (2009) Nat. Neurosci. , vol.12 , pp. 399-408
    • Cheng, L.C.1    Pastrana, E.2    Tavazoie, M.3    Doetsch, E.4
  • 14
    • 44449132518 scopus 로고    scopus 로고
    • Dicer loss in striatal neurons produces behavioral and neuroanatom-ical phenotypes in the absence of neurodegeneration
    • Cuellar, T. L., Davis, T. H., Nelson, P. T., Loeb, G. B., Harfe, B. D., Ullian, E., and McManus, M. T. (2008). Dicer loss in striatal neurons produces behavioral and neuroanatom-ical phenotypes in the absence of neurodegeneration. Proc. Natl. Acad. Sci. U.S.A. 105, 5614-5619.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 5614-5619
    • Cuellar, T.L.1    Davis, T.H.2    Nelson, P.T.3    Loeb, G.B.4    Harfe, B.D.5    Ullian, E.6    McManus, M.T.7
  • 15
    • 43749120042 scopus 로고    scopus 로고
    • Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus
    • Davis, T. H., Cuellar, T. L., Koch, S. M., Barker, A. J., Harfe, B. D., McManus, M. T., and Ullian, E. M. (2008). Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. J. Neurosci. 28, 4322-4330.
    • (2008) J. Neurosci. , vol.28 , pp. 4322-4330
    • Davis, T.H.1    Cuellar, T.L.2    Koch, S.M.3    Barker, A.J.4    Harfe, B.D.5    McManus, M.T.6    Ullian, E.M.7
  • 16
    • 79955538772 scopus 로고    scopus 로고
    • In sickness and in health: the role of methyl-CpG binding protein 2 in the central nervous system
    • de Leon-Guerrero, S. D., Pedraza-Alva, G., and Perez-Martinez, L. (2011). In sickness and in health: the role of methyl-CpG binding protein 2 in the central nervous system. Eur. J. Neurosci. 33, 1563-1574.
    • (2011) Eur. J. Neurosci. , vol.33 , pp. 1563-1574
    • de Leon-Guerrero, S.D.1    Pedraza-Alva, G.2    Perez-Martinez, L.3
  • 17
    • 69849090240 scopus 로고    scopus 로고
    • Fragile X syndrome: from molecular genetics to therapy
    • D'Hulst, C., and Kooy, R. E (2009). Fragile X syndrome: from molecular genetics to therapy. J. Med. Genet. 46, 577-584.
    • (2009) J. Med. Genet. , vol.46 , pp. 577-584
    • D'Hulst, C.1    Kooy, R.E.2
  • 23
    • 84864373960 scopus 로고    scopus 로고
    • Imprinted DLK1-DIO3 region of 14q32 defines a schizophrenia-associated miRNA signature in peripheral blood mononuclear cells
    • Gardiner, E., Beveridge, N. J., Wu, J. Q., Carr, V., Scott, R. J., Tooney, P. A., and Cairns, M. J. (2011). Imprinted DLK1-DIO3 region of 14q32 defines a schizophrenia-associated miRNA signature in peripheral blood mononuclear cells. Mol. Psychiatry.
    • (2011) Mol. Psychiatry.
    • Gardiner, E.1    Beveridge, N.J.2    Wu, J.Q.3    Carr, V.4    Scott, R.J.5    Tooney, P.A.6    Cairns, M.J.7
  • 24
    • 0033985644 scopus 로고    scopus 로고
    • Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia
    • Glantz, L. A., and Lewis, D. A. (2000). Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. Arch. Gen. Psychiatry 57, 65-73.
    • (2000) Arch. Gen. Psychiatry , vol.57 , pp. 65-73
    • Glantz, L.A.1    Lewis, D.A.2
  • 26
    • 77949426688 scopus 로고    scopus 로고
    • A novel microRNA and transcription factor mediated regulatory network in schizophrenia
    • doi:10.1186/1752-0509-4-10
    • Guo, A. Y., Sun, J., Jia, P., and Zhao, Z. (2010). A novel microRNA and transcription factor mediated regulatory network in schizophrenia. BMC Syst. Biol. 4, 10. doi:10.1186/1752-0509-4-10
    • (2010) BMC Syst. Biol. , vol.4 , pp. 10
    • Guo, A.Y.1    Sun, J.2    Jia, P.3    Zhao, Z.4
  • 27
    • 78649739197 scopus 로고    scopus 로고
    • Transgenic miR132 alters neuronal spine density and impairs novel object recognition memory
    • doi: 10.1371/journal.pone.00 15497
    • Hansen, K. F., Sakamoto, K., Wayman, G. A., Impey, S., and Obrietan, K. (2010). Transgenic miR132 alters neuronal spine density and impairs novel object recognition memory. PLoS ONE 5, e15497. doi: 10.1371/journal.pone.00 15497
    • (2010) PLoS ONE , vol.5
    • Hansen, K.F.1    Sakamoto, K.2    Wayman, G.A.3    Impey, S.4    Obrietan, K.5
  • 30
    • 84862922523 scopus 로고    scopus 로고
    • Cell-type-based analysis of microRNA profiles in the mouse brain
    • He, M., Liu, Y., Wang, X., Zhang, M. Q., Hannon, G. J., and Huang, Z. J. (2012). Cell-type-based analysis of microRNA profiles in the mouse brain. Neuron 73, 35-48.
    • (2012) Neuron , vol.73 , pp. 35-48
    • He, M.1    Liu, Y.2    Wang, X.3    Zhang, M.Q.4    Hannon, G.J.5    Huang, Z.J.6
  • 32
    • 72049108920 scopus 로고    scopus 로고
    • Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders
    • Hutsler, J. J., and Zhang, H. (2000). Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders. Brain Res. 1309,83-94.
    • (2000) Brain Res , vol.1309 , pp. 83-94
    • Hutsler, J.J.1    Zhang, H.2
  • 33
    • 77955992756 scopus 로고    scopus 로고
    • STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer
    • Iliopoulos, D., Jaeger, S. A., Hirsch, H. A., Bulyk, M. L., and Struhl, K. (2010). STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer. Mol. Cell 39, 493-506.
    • (2010) Mol. Cell , vol.39 , pp. 493-506
    • Iliopoulos, D.1    Jaeger, S.A.2    Hirsch, H.A.3    Bulyk, M.L.4    Struhl, K.5
  • 34
    • 77956141295 scopus 로고    scopus 로고
    • MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212
    • Im, H. I., Hollander, J. A., Bali, P., and Kenny, P. J. (2011). MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212. Nat. Neurosci. 13,1120-1127.
    • (2011) Nat. Neurosci. , vol.13 , pp. 1120-1127
    • Im, H.I.1    Hollander, J.A.2    Bali, P.3    Kenny, P.J.4
  • 37
    • 36448969801 scopus 로고    scopus 로고
    • Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA
    • Klein, M. E., Lioy, D. T., Ma, L., Impey, S., Mandel, G., and Goodman, R. H. (2007). Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA. Nat. Neurosci. 10, 1513-1514.
    • (2007) Nat. Neurosci. , vol.10 , pp. 1513-1514
    • Klein, M.E.1    Lioy, D.T.2    Ma, L.3    Impey, S.4    Mandel, G.5    Goodman, R.H.6
  • 39
    • 19944397113 scopus 로고    scopus 로고
    • Ultrastructural alterations in hippocampal mossy fiber synapses in Schizophrenia: a postmortem morphometric study
    • Kolomeets, N. S., Orlovskaya, D. D., Rachmanova, V. I., and Uranova, N. A. (2005). Ultrastructural alterations in hippocampal mossy fiber synapses in Schizophrenia: a postmortem morphometric study. Synapse 57, 47-55.
    • (2005) Synapse , vol.57 , pp. 47-55
    • Kolomeets, N.S.1    Orlovskaya, D.D.2    Rachmanova, V.I.3    Uranova, N.A.4
  • 41
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • Krol, J., Loedige, I., and Filipowicz, W (2010a). The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 11, 597-610.
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 597-610
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 43
    • 77951976180 scopus 로고    scopus 로고
    • miR-132 regulates antiviral innate immunity through suppression of the p300 transcriptional co-activator
    • Lagos, D., Pollara, G., Henderson, S., Gratrix, F., Fabani, M., Milne, R. S., Gotch, F., and Boshoff, C. (2010). miR-132 regulates antiviral innate immunity through suppression of the p300 transcriptional co-activator. Nat Cell Biol. 12,513-519.
    • (2010) Nat Cell Biol , vol.12 , pp. 513-519
    • Lagos, D.1    Pollara, G.2    Henderson, S.3    Gratrix, F.4    Fabani, M.5    Milne, R.S.6    Gotch, F.7    Boshoff, C.8
  • 46
    • 0027751663 scopus 로고
    • The C. elegans hete-rochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee, R. C., Feinbaum, R. L., and Ambros, V. (1993). The C. elegans hete-rochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75, 843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 48
    • 77951499826 scopus 로고    scopus 로고
    • Roles of small regulatory RNAs in determining neuronal identity
    • Li, X., and Jin, P. (2010). Roles of small regulatory RNAs in determining neuronal identity. Nat. Rev. Neurosci. 11,329-338.
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 329-338
    • Li, X.1    Jin, P.2
  • 50
    • 69149102249 scopus 로고    scopus 로고
    • miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination
    • Lin, S. T., and Fu, Y H. (2009). miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination. Dis. Model. Mech. 2, 178-188.
    • (2009) Dis. Model. Mech. , vol.2 , pp. 178-188
    • Lin, S.T.1    Fu, Y.H.2
  • 54
    • 34547212309 scopus 로고    scopus 로고
    • The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing
    • Makeyev, E. V., Zhang, J., Carrasco, M. A., and Maniatis, T. (2007). The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol. Cell 27,435-448.
    • (2007) Mol. Cell , vol.27 , pp. 435-448
    • Makeyev, E.V.1    Zhang, J.2    Carrasco, M.A.3    Maniatis, T.4
  • 55
    • 84860213619 scopus 로고    scopus 로고
    • Gender-specific reduction of estrogen-sensitive small RNA, miR-30b, in subjects with Schizophrenia
    • doi: 10.1093/schbul/sbq091
    • Mellios, N., Galdzicka, M., Ginns, E., Baker, S. P., Rogaev, E., Xu, J., and Akbarian, S. (2010). Gender-specific reduction of estrogen-sensitive small RNA, miR-30b, in subjects with Schizophrenia. Schizophr. Bull. doi: 10.1093/schbul/sbq091
    • (2010) Schizophr. Bull
    • Mellios, N.1    Galdzicka, M.2    Ginns, E.3    Baker, S.P.4    Rogaev, E.5    Xu, J.6    Akbarian, S.7
  • 56
    • 67349117808 scopus 로고    scopus 로고
    • Molecular determinants of dysregulated GABAergic gene expression in the prefrontal cortex of subjects with Schizophrenia
    • Mellios, N., Huang, H. S., Baker, S. P., Galdzicka, M., Ginns, E., and Akbarian, S. (2009). Molecular determinants of dysregulated GABAergic gene expression in the prefrontal cortex of subjects with Schizophrenia. Biol. Psychiatry 65,1006-1014.
    • (2009) Biol. Psychiatry , vol.65 , pp. 1006-1014
    • Mellios, N.1    Huang, H.S.2    Baker, S.P.3    Galdzicka, M.4    Ginns, E.5    Akbarian, S.6
  • 57
    • 52949109849 scopus 로고    scopus 로고
    • A set of differentially expressed miRNAs, including miR-30a-5p, act as post-transcriptional inhibitors of BDNF in prefrontal cortex
    • Mellios, N., Huang, H. S., Grigorenko, A., Rogaev, E., and Akbarian, S. (2008). A set of differentially expressed miRNAs, including miR-30a-5p, act as post-transcriptional inhibitors of BDNF in prefrontal cortex. Hum. Mol. Genet. 17, 3030-3042.
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 3030-3042
    • Mellios, N.1    Huang, H.S.2    Grigorenko, A.3    Rogaev, E.4    Akbarian, S.5
  • 62
    • 78650446774 scopus 로고    scopus 로고
    • Altered microRNA expression profiles in postmortem brain samples from individuals with Schizophrenia and bipolar disorder
    • Moreau, M. P., Bruse, S. E., David-Rus, R., Buyske, S., and Brzustow-icz, L. M. (2011). Altered microRNA expression profiles in postmortem brain samples from individuals with Schizophrenia and bipolar disorder. Biol. Psychiatry 69,188-193.
    • (2011) Biol. Psychiatry , vol.69 , pp. 188-193
    • Moreau, M.P.1    Bruse, S.E.2    David-Rus, R.3    Buyske, S.4    Brzustow-icz, L.M.5
  • 63
    • 78149443144 scopus 로고    scopus 로고
    • The microRNA and messengerRNA profile of the RNA-induced silencing complex in human primary astrocyte and astrocytoma cells
    • doi:10.1371/jour-nal.pone.0013445
    • Moser, J. J., and Fritzler, M. J. (2010). The microRNA and messengerRNA profile of the RNA-induced silencing complex in human primary astrocyte and astrocytoma cells. PLoS ONE 5, e13445. doi:10.1371/jour-nal.pone.0013445
    • (2010) PLoS ONE , vol.5
    • Moser, J.J.1    Fritzler, M.J.2
  • 64
    • 0032882849 scopus 로고    scopus 로고
    • High rates of schizophrenia in adults with velo-cardio-facial syndrome
    • Murphy, K. C., Jones, L. A., and Owen, M. J. (1999). High rates of schizophrenia in adults with velo-cardio-facial syndrome. Arch. Gen. Psychiatry 56, 940-945.
    • (1999) Arch. Gen. Psychiatry , vol.56 , pp. 940-945
    • Murphy, K.C.1    Jones, L.A.2    Owen, M.J.3
  • 67
    • 84857190395 scopus 로고    scopus 로고
    • The role of immune dysfunction in the pathophysiology of autism
    • Onore, C., Careaga, M., and Ashwood, P. (2012). The role of immune dysfunction in the pathophysiology of autism. Brain Behav. Immun. 26, 383-392.
    • (2012) Brain Behav. Immun. , vol.26 , pp. 383-392
    • Onore, C.1    Careaga, M.2    Ashwood, P.3
  • 71
    • 33846277696 scopus 로고    scopus 로고
    • Repression of protein synthesis by miRNAs: how many mechanisms?
    • Pillai, R. S., Bhattacharyya, S. N., and Filipowicz, W. (2007). Repression of protein synthesis by miRNAs: how many mechanisms? Trends Cell Biol. 17,118-126.
    • (2007) Trends Cell Biol , vol.17 , pp. 118-126
    • Pillai, R.S.1    Bhattacharyya, S.N.2    Filipowicz, W.3
  • 72
    • 78651247933 scopus 로고    scopus 로고
    • MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU 1 pathway
    • Ponomarev, E. D., Veremeyko, T., Barteneva, N., Krichevsky, A. M., and Weiner, H. L. (2011). MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway. Nat. Med. 17, 64-70.
    • (2011) Nat. Med. , vol.17 , pp. 64-70
    • Ponomarev, E.D.1    Veremeyko, T.2    Barteneva, N.3    Krichevsky, A.M.4    Weiner, H.L.5
  • 77
    • 78650511568 scopus 로고    scopus 로고
    • Upregulation of dicer and microRNA expression in the dorso-lateral prefrontal cortex Brodmann area 46 in schizophrenia
    • Santarelli, D. M., Beveridge, N. J., Tooney, P. A., and Cairns, M. J. (2011). Upregulation of dicer and microRNA expression in the dorso-lateral prefrontal cortex Brodmann area 46 in schizophrenia. Biol. Psychiatry 69,180-187.
    • (2011) Biol. Psychiatry , vol.69 , pp. 180-187
    • Santarelli, D.M.1    Beveridge, N.J.2    Tooney, P.A.3    Cairns, M.J.4
  • 78
    • 78751689926 scopus 로고    scopus 로고
    • Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines
    • Sarachana, T., Zhou, R., Chen, G., Manji, H. K., and Hu, V. W. (2010). Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines. Genome Med. 2,23.
    • (2010) Genome Med , vol.2 , pp. 23
    • Sarachana, T.1    Zhou, R.2    Chen, G.3    Manji, H.K.4    Hu, V.W.5
  • 79
    • 79953278448 scopus 로고    scopus 로고
    • Monoallelic deletion of the microRNA biogenesis gene Dgcr8 produces deficits in the development of excitatory synaptic transmission in the prefrontal cortex
    • Schofield, C. M., Hsu, R., Barker, A. J., Gertz, C. C., Blelloch, R., and Ullian, E. M. (2011). Monoallelic deletion of the microRNA biogenesis gene Dgcr8 produces deficits in the development of excitatory synaptic transmission in the prefrontal cortex. Neural Dev. 6,11.
    • (2011) Neural Dev , vol.6 , pp. 11
    • Schofield, C.M.1    Hsu, R.2    Barker, A.J.3    Gertz, C.C.4    Blelloch, R.5    Ullian, E.M.6
  • 82
    • 71749084011 scopus 로고    scopus 로고
    • MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase
    • Shaked, I., Meerson, A., Wolf, Y., Avni, R., Greenberg, D., Gilboa-Geffen, A., and Soreq, H. (2009). MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase. Immunity 31, 965-973.
    • (2009) Immunity , vol.31 , pp. 965-973
    • Shaked, I.1    Meerson, A.2    Wolf, Y.3    Avni, R.4    Greenberg, D.5    Gilboa-Geffen, A.6    Soreq, H.7
  • 84
    • 73549104488 scopus 로고    scopus 로고
    • Dicer ablation in oligodendrocytes provokes neuronal impairment in mice
    • Shin, D., Shin, J. Y., McManus, M. T., Ptacek, L. J., and Fu, Y H. (2009). Dicer ablation in oligodendrocytes provokes neuronal impairment in mice. Ann. Neurol. 66, 843-857.
    • (2009) Ann. Neurol. , vol.66 , pp. 843-857
    • Shin, D.1    Shin, J.Y.2    McManus, M.T.3    Ptacek, L.J.4    Fu, Y.H.5
  • 86
    • 38949191397 scopus 로고    scopus 로고
    • Exosomal transfer of proteins and RNAs at synapses in the nervous system?
    • Smalheiser, N. R. (2007). Exosomal transfer of proteins and RNAs at synapses in the nervous system? Biol. Direct 2, 35.
    • (2007) Biol Direct , vol.2 , pp. 35
    • Smalheiser, N.R.1
  • 91
    • 57849160321 scopus 로고    scopus 로고
    • Reduced dendritic spine density in auditory cor tex of subjects with schizophre nia
    • Sweet, R. A., Henteleff, R. A., Zhang, W., Sampson, A. R., and Lewis, D A. (2009). Reduced dendritic spine density in auditory cor tex of subjects with schizophre nia. Neuropsychopharmacology 34, 374-389.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 374-389
    • Sweet, R.A.1    Henteleff, R.A.2    Zhang, W.3    Sampson, A.R.4    Lewis, D.A.5
  • 93
    • 33747608638 scopus 로고    scopus 로고
    • NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov, K. D., Boldin, M. P., Chang, K. J., and Baltimore, D. (2006). NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc. Natl. Acad. Sci. U.S.A. 103, 12481-12486.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 94
    • 66349107637 scopus 로고    scopus 로고
    • Feasibility and relevance of examining lym-phoblastoid cell lines to study role of microRNAs in autism
    • Talebizadeh, Z., Butler, M. G., and Theodoro, M. E (2008). Feasibility and relevance of examining lym-phoblastoid cell lines to study role of microRNAs in autism. Autism Res. 1, 240-250.
    • (2008) Autism Res , vol.1 , pp. 240-250
    • Talebizadeh, Z.1    Butler, M.G.2    Theodoro, M.E.3
  • 96
    • 80053255519 scopus 로고    scopus 로고
    • Experience-dependent expression of miR-132 regulates ocular dominance plasticity
    • Tognini, P., Putignano, E., Coatti, A., and Pizzorusso, T. (2011). Experience-dependent expression of miR-132 regulates ocular dominance plasticity. Nat. Neurosci. 14, 1237-1239.
    • (2011) Nat. Neurosci. , vol.14 , pp. 1237-1239
    • Tognini, P.1    Putignano, E.2    Coatti, A.3    Pizzorusso, T.4
  • 97
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • Valadi, H., Ekstrom, K., Bossios, A., Sjostrand, M., Lee, J. J., and Lotvall, J. O. (2007). Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat. Cell Biol. 9, 654-659.
    • (2007) Nat. Cell Biol. , vol.9 , pp. 654-659
    • Valadi, H.1    Ekstrom, K.2    Bossios, A.3    Sjostrand, M.4    Lee, J.J.5    Lotvall, J.O.6
  • 98
    • 62149104335 scopus 로고    scopus 로고
    • The prevalence of PTEN mutations in a clinical pediatric cohort with autism spectrum disorders, developmental delay, and macrocephaly
    • Varga, E. A., Pastore, M., Prior, T., Herman, G. E., and McBride, K. L. (2009). The prevalence of PTEN mutations in a clinical pediatric cohort with autism spectrum disorders, developmental delay, and macrocephaly. Genet. Med. 11, 111-117.
    • (2009) Genet. Med. , vol.11 , pp. 111-117
    • Varga, E.A.1    Pastore, M.2    Prior, T.3    Herman, G.E.4    McBride, K.L.5
  • 99
    • 34147157651 scopus 로고    scopus 로고
    • The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development
    • Visvanathan, J., Lee, S., Lee, B., Lee, J. W., and Lee, S. K. (2007). The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development. Genes Dev. 21, 744-749.
    • (2007) Genes Dev , vol.21 , pp. 744-749
    • Visvanathan, J.1    Lee, S.2    Lee, B.3    Lee, J.W.4    Lee, S.K.5
  • 101
    • 50949132066 scopus 로고    scopus 로고
    • Human cytomegalovirus infection alters the expression of cellular microRNA species that affect its replication
    • Wang, F. Z., Weber, F., Croce, C., Liu, C. G., Liao, X., and Pellett, P. E. (2008). Human cytomegalovirus infection alters the expression of cellular microRNA species that affect its replication. J. Virol. 82, 9065-9074.
    • (2008) J. Virol. , vol.82 , pp. 9065-9074
    • Wang, F.Z.1    Weber, F.2    Croce, C.3    Liu, C.G.4    Liao, X.5    Pellett, P.E.6
  • 103
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C.
    • Wightman, B., Ha, I., and Ruvkun, G. (1993). Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75, 855-862.
    • (1993) elegans Cell , vol.75 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 104
    • 80055089607 scopus 로고    scopus 로고
    • The utility of gene expression in blood cells for diagnosing neuropsychiatric disorders
    • Woelk, C. H., Singhania, A., Perez-Santiago, J., Glatt, S. J., and Tsuang, M. T. (2011). The utility of gene expression in blood cells for diagnosing neuropsychiatric disorders. Int. Rev. Neurobiol. 101, 41-63.
    • (2011) Int. Rev. Neurobiol. , vol.101 , pp. 41-63
    • Woelk, C.H.1    Singhania, A.2    Perez-Santiago, J.3    Glatt, S.J.4    Tsuang, M.T.5
  • 105
    • 78149248751 scopus 로고    scopus 로고
    • Genome-wide analysis reveals methyl-CpG-binding protein 2-dependent regulation of microRNAs in a mouse model of Rett syndrome
    • Wu, H., Tao, J., Chen, P. J., Shahab, A., Ge, W., Hart, R. P., Ruan, X., Ruan, Y., and Sun, Y E. (2010). Genome-wide analysis reveals methyl-CpG-binding protein 2-dependent regulation of microRNAs in a mouse model of Rett syndrome. Proc. Natl. Acad. Sci. U.S.A. 107, 18161-18166.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 18161-18166
    • Wu, H.1    Tao, J.2    Chen, P.J.3    Shahab, A.4    Ge, W.5    Hart, R.P.6    Ruan, X.7    Ruan, Y.8    Sun, Y.E.9
  • 106
    • 77952670366 scopus 로고    scopus 로고
    • MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia
    • Xu, Y., Li, F., Zhang, B., Zhang, K., Zhang, F., Huang, X., Sun, N., Ren, Y., Sui, M., and Liu, P. (2010). MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. Schizophr. Res. 119,219-227.
    • (2010) Schizophr. Res. , vol.119 , pp. 219-227
    • Xu, Y.1    Li, F.2    Zhang, B.3    Zhang, K.4    Zhang, F.5    Huang, X.6    Sun, N.7    Ren, Y.8    Sui, M.9    Liu, P.10
  • 107
    • 48849103603 scopus 로고    scopus 로고
    • MicroRNAmiR-124 regulates neurite outgrowth during neuronal differentiation
    • Yu, J. Y., Chung, K. H., Deo, M., Thompson, R. C., and Turner, D. L. (2008). MicroRNAmiR-124 regulates neurite outgrowth during neuronal differentiation. Exp. Cell Res. 314,2618-2633.
    • (2008) Exp. Cell Res. , vol.314 , pp. 2618-2633
    • Yu, J.Y.1    Chung, K.H.2    Deo, M.3    Thompson, R.C.4    Turner, D.L.5
  • 108
    • 79961187284 scopus 로고    scopus 로고
    • Downregulation of miR-132 by promoter methyla-tion contributes to pancreatic cancer development
    • Zhang, S., Hao, J., Xie, F., Hu, X., Liu, C., Tong, J., Zhou, J., Wu, J., and Shao, C. (2011). Downregulation of miR-132 by promoter methyla-tion contributes to pancreatic cancer development. Carcinogenesis 32, 1183-1189.
    • (2011) Carcinogenesis , vol.32 , pp. 1183-1189
    • Zhang, S.1    Hao, J.2    Xie, F.3    Hu, X.4    Liu, C.5    Tong, J.6    Zhou, J.7    Wu, J.8    Shao, C.9
  • 109
    • 62649165347 scopus 로고    scopus 로고
    • A MicroRNA gene is hosted in an intron of aschizophrenia-susceptibility gene
    • Zhu, Y., Kalbfleisch, T., Brennan, M.D., and Li, Y. (2009). A MicroRNA gene is hosted in an intron of aschizophrenia-susceptibility gene. Schizophr. Res. 109, 86-89.
    • (2009) Schizophr. Res , vol.109 , pp. 86-89
    • Zhu, Y.1    Kalbfleisch, T.2    Brennan, M.D.3    Li, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.