SIRT1 regulates TNF-α-induced expression of CD40 in 3T3-L1 adipocytes via NF-κB pathway

Cytokine

Volumn 60, Issue 2, 2012, Pages 447-455

  Lin, Qin Qin ^a   Yan, Chun Fang ^b   Lin, Rong ^a   Zhang, Ji Ye ^a   Wang, Wei Rong ^a   Yang, Li Na ^a   Zhang, Kai Fan ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b Fourth Hospital of Xi'an City   (China)

Author keywords

3T3 L1 adipocytes; CD40; Inflammation; NF B; SIRT1

Indexed keywords

CD40 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; NICOTINAMIDE; PYRROLIDINE DITHIOCARBAMATE; RESVERATROL; SIRTUIN 1; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ACETYLATION; ADIPOCYTE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL NUCLEUS; CELL STRAIN 3T3; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; GENE SILENCING; INHIBITION KINETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION;

3T3-L1 CELLS; ACETYLATION; ADIPOCYTES; ANIMALS; ANTIGENS, CD40; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; MICE; NF-KAPPA B; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SIRTUIN 1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84866771337     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2012.05.025     Document Type: Article

References (38)

1. Michan S., Sinclair D. Sirtuins in mammals: insights into their biological function. Biochem J 2007, 404:1-13.
2. Frye R.A. Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. Biochem Biophys Res Commun 2000, 273:793-798.
3. Haigis M.C., Sinclair D.A. Mammalian sirtuins: biological insights and disease relevance. Annu Rev Pathol 2010, 5:253-295.
4. Picard F., Kurtev M., Chung N., Topark-Ngarm A., Senawong T., Machado De Oliveira R., et al. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature 2004, 429:771-776.
5. Yoshizaki T., Milne J.C., Imamura T., Schenk S., Sonoda N., Babendure J.L., et al. SIRT1 exerts anti-inflammatory effects and improves insulin sensitivity in adipocytes. Mol Cell Biol 2009, 29:1363-1374.
6. Lee S.J., Kim M.M. Resveratrol with antioxidant activity inhibits matrix metalloproteinase via modulation of SIRT1 in human fibrosarcoma cells. Life Sci 2011, 88:465-472.
7. Zhang C., Feng Y., Qu S., Wei X., Zhu H., Luo Q., et al. Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53. Cardiovasc Res 2011, 90:538-545.
8. Olholm J., Paulsen S.K., Cullberg K.B., Richelsen B., Pedersen S.B. Anti-inflammatory effect of resveratrol on adipokine expression and secretion in human adipose tissue explants. Int J Obesity 2010, 34:1546-1553.
9. Rizvi M., Pathak D., Freedman J.E., Chakrabarti S. CD40-CD40 ligand interactions in oxidative stress, inflammation and vascular disease. Trends Mol Med 2008, 14:530-538.
10. Poggi M., Jager J., Paulmyer-Lacroix O., Peiretti F., Gremeaux T., Verdier M., et al. The inflammatory receptor CD40 is expressed on human adipocytes: contribution to crosstalk between lymphocytes and adipocytes. Diabetologia 2009, 52:1152-1163.
11. Missiou A., Wolf D., Platzer I., Ernst S., Walter C., Rudolf P., et al. CD40L induces inflammation and adipogenesis in adipose cells-a potential link between metabolic and cardiovascular disease. Thromb Haemostasis 2010, 103:788-796.
12. Tone M., Tone Y., Babik J.M., Lin C.Y., Waldmann H. The role of Sp1 and NF-κB in regulating CD40 gene expression. J Biol Chem 2002, 277:8890-8897.
13. Krzesz R., Wagner A.H., Cattaruzza M., Hecker M. Cytokine-inducible CD40 gene expression in vascular smooth muscle cells is mediated by nuclear factor kappaB and signal transducer and activato of transcription-1. FEBS Lett 1999, 453:191-196.
14. Lin R., Liu J.T., Peng N., Yang G.D., Gan W.J., Wang W.R. Lovastatin reduces nuclear factor kappa B activation induced by C-reactive protein in human vascular endothelial cells. Biol Pharm Bull 2005, 28:1630-1634.
15. Csiszar A., Labinskyy N., Podlutsky A., Kaminski P.M., Wolin M.S., Zhang C., et al. Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations. Am J Physiol Heart Circ Physiol 2008, 294:H2721-H2735.
16. Lee J.H., Song M.Y., Song E.K., Kim E.K., Moon W.S., Han M.K., et al. Overexpression of SIRT1 protects pancreatic beta-cells against cytokine toxicity by suppressing the nuclear factor-kappaB signaling pathway. Diabetes 2009, 58:344-351.
17. Pfluger P.T., Herranz D., Velasco-Miguel S., Serrano M., Tschop M.H. Sirt1 protects against high-fat diet-induced metabolic damage. Proc Natl Acad Sci USA 2008, 105:9793-9798.
18. Nelson B.A., Robinson K.A., Buse M.G. High glucose and glucosamine induce insulin resistance via different mechanisms in 3T3-L1 adipocytes. Diabetes 2000, 49:981-991.
19. Lin Q.Q., Lin R., Ji Q.L., Zhang J.Y., Wang W.R., Yang L.N., et al. Effect of exercise training on renal function and renal aquaporin-2 expression in rats with chronic heart failure. Clin Exp Pharmacol Physiol 2011, 38:179-185.
20. Michishita E., Park J.Y., Burneskis J.M., Barrett J.C., Horikawa I. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol Biol Cell 2005, 16:4623-4635.
21. Sakamoto J., Miura T., Shimamoto K., Horio Y. Predominant expression of Sir2α, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain. FEBS Lett 2004, 556:281-286.
22. Sugino T., Maruyama M., Tanno M., Kuno A., Houkin K., Horio Y. Protein deacetylase SIRT1 in the cytoplasm promotes nerve growth factor-induced neurite outgrowth in PC12 cells. FEBS Lett 2010, 584:2821-2826.
23. Jin Q., Yan T., Ge X., Sun C., Shi X., Zhai Q. Cytoplasm-localized SIRT1 enhances apoptosis. J Cell Physiol 2007, 213:88-97.
24. Tanno M., Sakamoto J., Miura T., Shimamoto K., Horio Y. Nucleocytoplasmic shuttling of the NAD(+)- dependent histone deacrtylase SIRT1. J Biol Chem 2007, 282:6823-6832.
25. Dvir-Ginzberg M., Gagarina V., Lee E.J., Booth R., Gabay O., Hall D.J. Tumor necrosis factor alpha-mediated cleavage and inactivation of sirT1 in human osteoarthritic chondrocytes. Arthritis Rheum 2011, 63:2363-2373.
26. Hsu C.P., Zhai P., Yamamoto T., Maejima Y., Matsushima S., Hariharan N., et al. Silent information regulator 1 protects the heart from ischemia/reperfusion. Circulation 2010, 122:2170-2182.
27. Zhang H.N., Li L., Gao P., Chen H.Z., Zhang R., Wei Y.S., et al. Involvement of the p65/RelA subunit of NF-kappa B in TNF-alpha-induced SIRT1 expression in vascular smooth muscle cells. Biochem Biophys Res Commun 2010, 397:569-575.
28. Alcendor R.R., Gao S., Zhai P., Zablocki D., Holle E., Yu X., et al. Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ Res 2007, 100:1512-1521.
29. Häkkinen T., Karkola K., Ylä-Herttuala S. Macrophages, smooth muscle cells, endothelial cells, and T-cells express CD40 and CD40L in fatty streaks and more advanced human atherosclerotic lesions. Colocalization with epitopes of oxidized low-density lipoprotein, scavenger receptor, and CD16 (Fc gammaRIII). Virchows Arch 2000, 437:396-405.
30. Tkacova R., Ukropec J., Skyba P., Ukropcova B., Pobeha P., Kurdiova T., et al. Increased adipose tissue expression of proinflammatory CD40, MKK4 and JNK in patients with very severe chronic obstructive pulmonary disease. Respiration 2011, 81:386-393.
31. Gocmen A.Y., Burgucu D., Gumuslu S. Effect of resveratrol on platelet activation in hypercholesterolemic rats: CD40- CD40L system as a potential target. Appl Physiol Nutr Metab 2011, 36:323-330.
32. Csiszar A., Labinskyy N., Jimenez R., Pinto J.T., Ballabh P., Losonczy G., et al. Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1. Mech Ageing Dev 2009, 130:518-527.
33. Schug T.T., Xu Q., Gao H., Peres-da-Silva A., Draper D.W., Fessler M.B., et al. Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress. Mol Cell Biol 2010, 30:4712-4721.
34. Yeung F., Hoberg J.E., Ramsey C.S., Keller M.D., Jones D.R., Frye R.A., et al. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. Embo J 2004, 23:2369-2380.
35. Cheng H.L., Mostoslavsky R., Saito S., Manis J.P., Gu Y., Patel P., et al. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci USA 2003, 100:10794-10799.
36. Tak P.P., Firestein G.S. NF-kappaB: a key role in inflammatory diseases. J Clin Invest 2001, 107:7-11.
37. Chen L.F., Mu Y., Greene W.C. Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-κB. EMBO J 2002, 21:6539-6548.
38. Zhu X., Liu Q., Wang M., Liang M., Yang X., Xu X., et al. Activation of sirt1 by resveratrol inhibits TNF-α induced inflammation in fibroblasts. PLoS One 2011, 6:e27081.