-
1
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
BONNER JA, HARARI PM, GIRALT J, AZARNIA N, SHIN DM et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006; 354: 567-678. http://dx.doi.org/10.1056/NEJMoa053422
-
(2006)
N Engl J Med
, vol.354
, pp. 567-678
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
Azarnia, N.4
Shin, D.M.5
-
2
-
-
34250155320
-
Epidermal growth factor receptor copy number alterations correlate with poor clinical outcome in patients with head and neck squamous cancer
-
TEMAM S, KAWAGUCHI H, EL-NAGGAR AK, JELINEK J, TANG H et al. Epidermal growth factor receptor copy number alterations correlate with poor clinical outcome in patients with head and neck squamous cancer. J Clin Oncol 2007; 25: 2164-2170. http://dx.doi.org/10.1200/JCO.2006.06.6605
-
(2007)
J Clin Oncol
, vol.25
, pp. 2164-2170
-
-
Temam, S.1
Kawaguchi, H.2
El-Naggar, A.K.3
Jelinek, J.4
Tang, H.5
-
3
-
-
44649115694
-
Targeting epidermal growth factor receptor and SRC pathways in head and neck cancer
-
EGLOFF AM, GRANDIS JR. Targeting epidermal growth factor receptor and SRC pathways in head and neck cancer. Semin Oncol 2008; 35: 286-297. http://dx.doi.org/10.1053/j.seminoncol.2008.03.008
-
(2008)
Semin Oncol
, vol.35
, pp. 286-297
-
-
Egloff, A.M.1
Grandis, J.R.2
-
4
-
-
84859243184
-
The Nuclear Epidermal Growth Factor Receptor Signaling Network and Its Role in Cancer
-
BRAND TM, IIDA M, CHUNRONG L, WHEELER DL. The Nuclear Epidermal Growth Factor Receptor Signaling Network and Its Role in Cancer. Discov Med 2011; 12: 419-432.
-
(2011)
Discov Med
, vol.12
, pp. 419-432
-
-
Brand, T.M.1
Iida, M.2
Chunrong, L.3
Wheeler, D.L.4
-
5
-
-
79958053606
-
Clinical significance of genetic alterations and expression of epidermal growth factor receptor (EGFR) in head and neck squamous cell carcinomas
-
SZABO B, NELHUBEL GA, KARPATI A, KENESSEY I, JORI B et al. Clinical significance of genetic alterations and expression of epidermal growth factor receptor (EGFR) in head and neck squamous cell carcinomas. Oral Oncology 2011; 47: 487-496. http://dx.doi.org/10.1016/j.oraloncology.2011.03.020
-
(2011)
Oral Oncology
, vol.47
, pp. 487-496
-
-
Szabo, B.1
Nelhubel, G.A.2
Karpati, A.3
Kenessey, I.4
Jori, B.5
-
6
-
-
68949201629
-
Activating and resistance mutations of EGFR in non-small-cell lung cancer: Role in clinical response to EGFR tyrosine kinase inhibitors
-
GAZDAR AF. Activating and resistance mutations of EGFR in non-small-cell lung cancer: role in clinical response to EGFR tyrosine kinase inhibitors. Oncogene 2009; 28(Suppl 1): 24-31. http://dx.doi.org/10.1038/onc.2009.198
-
(2009)
Oncogene
, vol.28
, Issue.SUPPL. 1
, pp. 24-31
-
-
Gazdar, A.F.1
-
7
-
-
77956268839
-
Understanding resistance to EGFR inhibitors-impact on future treatment strategies
-
WHEELER DL, DUNN EF HARARI PM. Understanding resistance to EGFR inhibitors-impact on future treatment strategies. Nature rewiewe Clin Oncol 2010; 7: 493-507.
-
(2010)
Nature rewiewe Clin Oncol
, vol.7
, pp. 493-507
-
-
Wheeler, D.L.1
Dunn Ef Harari, P.M.2
-
8
-
-
67650667527
-
Cigarettes smoking habit may reduce benefit from cetuximab-based treatment in advanced colorectal cancer patients
-
VINCENZI B, SANTINI D, LOUPAKIS F, ADDEO R, LLIMPE FLR et al. Cigarettes smoking habit may reduce benefit from cetuximab-based treatment in advanced colorectal cancer patients. Expert Opin Biol Ther 2009; 9: 945-949. http://dx.doi.org/10.1517/14712590903081694
-
(2009)
Expert Opin Biol Ther
, vol.9
, pp. 945-949
-
-
Vincenzi, B.1
Santini, D.2
Loupakis, F.3
Addeo, R.4
Llimpe, F.L.R.5
-
9
-
-
23844491524
-
Differential effects of gefitinib and cetuximab on non-small cell lung cancers bearing epidermal growth factor receptor mutations
-
MUKOHARA T, ENGELMAN JA, HANNA NH, YEAP BY, KOBAYASHI S et al. Differential effects of gefitinib and cetuximab on non-small cell lung cancers bearing epidermal growth factor receptor mutations. J Nat Cancer Inst 2005; 97: 1185-1194. http://dx.doi.org/10.1093/jnci/dji238
-
(2005)
J Nat Cancer Inst
, vol.97
, pp. 1185-1194
-
-
Mukohara, T.1
Engelman, J.A.2
Hanna, N.H.3
Yeap, B.Y.4
Kobayashi, S.5
-
10
-
-
33746896572
-
The evolving role of cetuximab in non-small cell lung cancer
-
LILENBAUM RC, JOHNSON B, LYNCH T, SANDLER A, BUNN P et al. The evolving role of cetuximab in non-small cell lung cancer. Clin Cancer Res 2006; 12: 4432-4435. http://dx.doi.org/10.1158/1078-0432.CCR-06-0097
-
(2006)
Clin Cancer Res
, vol.12
, pp. 4432-4435
-
-
Lilenbaum, R.C.1
Johnson, B.2
Lynch, T.3
Sandler, A.4
Bunn, P.5
-
11
-
-
33846244217
-
Epidermal Growtht Factor Receptor Activ ation: How Exon 19 and 21 Mutations Changed Our Understanding of the Pathway
-
ROSELL R, TARON M, REQUART N, ISLA D, MORAN T. Epidermal Growtht Factor Receptor Activ ation: How Exon 19 and 21 Mutations Changed Our Understanding of the Pathway. Clin Cancer Res 2006; 12: 7222-7230. http://dx.doi.org/10.1158/1078-0432.CCR-06-0627
-
(2006)
Clin Cancer Res
, vol.12
, pp. 7222-7230
-
-
Rosell, R.1
Taron, M.2
Requart, N.3
Isla, D.4
Moran, T.5
-
12
-
-
77951744287
-
New strategies in head and neck cancer: Understanding resistance to epidermal growth factor receptor inhibitors
-
CHEN L F, COHEN E E, GRANDIS J R. New strategies in head and neck cancer: understanding resistance to epidermal growth factor receptor inhibitors. Clinical Cancer Research 2010; 16: 2489-2495. http://dx.doi.org/10.1158/1078-0432.CCR-09-2318
-
(2010)
Clinical Cancer Research
, vol.16
, pp. 2489-2495
-
-
Chen, L.F.1
Cohen, E.E.2
Grandis, J.R.3
-
13
-
-
77950680537
-
Cetuximab-based immunotherapy and radioimmunotherapy of head and neck quamous cell carcinoma
-
NIU G, SUN X, CAO Q, COURTER D, KOONG A et al. Cetuximab-based immunotherapy and radioimmunotherapy of head and neck quamous cell carcinoma. Clinical Cancer Research 2010; 16: 2095-2105. http://dx.doi.org/10.1158/1078-0432.CCR-09-2495
-
(2010)
Clinical Cancer Research
, vol.16
, pp. 2095-2105
-
-
Niu, G.1
Sun, X.2
Cao, Q.3
Courter, D.4
Koong, A.5
-
14
-
-
33646228635
-
K-RAS mutation status is predictive of response to cetuximab therapy in colorectal cancer
-
LIEVRE A, BACHET JB, LE CORRE D, BOIGE V, LANDI B et al. K-RAS mutation status is predictive of response to cetuximab therapy in colorectal cancer. Cancer Research 2006; 66: 3992-3995. http://dx.doi.org/10.1158/0008-5472.CAN-06-0191
-
(2006)
Cancer Research
, vol.66
, pp. 3992-3995
-
-
Lievre, A.1
Bachet, J.B.2
Le Corre, D.3
Boige, V.4
Landi, B.5
-
15
-
-
34247278727
-
Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy
-
DI FIORE F, BLANCHARD F, CHARBONNIER F, LE PESSOT F, LAMY A et al. Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy. British Journal of Cancer 2007; 96: 1166-1169. http://dx.doi.org/10.1038/sj.bjc.6603685
-
(2007)
British Journal of Cancer
, vol.96
, pp. 1166-1169
-
-
Di Fiore, F.1
Blanchard, F.2
Charbonnier, F.3
Le Pessot, F.4
Lamy, A.5
-
16
-
-
4544258999
-
EGFR and EGFRvIII expression in primary breast cancer and cell lines
-
RAE JM, SCHEYS JO, CLARK KM, CHADWICK RB, KIEFER MC et al. EGFR and EGFRvIII expression in primary breast cancer and cell lines. Breast Cancer Res Treat 2004; 87: 87-95. http://dx.doi.org/10.1023/B:BREA.0000041585.26734.f9
-
(2004)
Breast Cancer Res Treat
, vol.87
, pp. 87-95
-
-
Rae, J.M.1
Scheys, J.O.2
Clark, K.M.3
Chadwick, R.B.4
Kiefer, M.C.5
-
17
-
-
0037444275
-
Distinct amplification of an untranslated regulatory sequence in the egfr gene contributes to early steps in breast cancer development
-
TIDOW N, BOECKER A, SCHMIDT H, AGELOPOULOS K, BOECKER W et all. Distinct amplification of an untranslated regulatory sequence in the egfr gene contributes to early steps in breast cancer development. Cancer Res 2003; 63: 1172-1178.
-
(2003)
Cancer Res
, vol.63
, pp. 1172-1178
-
-
Tidow, N.1
Boecker, A.2
Schmidt, H.3
Agelopoulos, K.4
Boecker, W.5
-
18
-
-
79960352442
-
Diverse effects of combined radiotherapy and EGFR inhibition with antibodies or TK inhibitors on local tumour control and correlation with EGFR gene expression
-
GURTNER K, DEUSE Y, BUTOF R, SCHAAL K, EICHELER W et al. Diverse effects of combined radiotherapy and EGFR inhibition with antibodies or TK inhibitors on local tumour control and correlation with EGFR gene expression. Radiotherapy and Oncology 2011; 99: 323-330. http://dx.doi.org/10.1016/j.radonc.2011.05.035
-
(2011)
Radiotherapy and Oncology
, vol.99
, pp. 323-330
-
-
Gurtner, K.1
Deuse, Y.2
Butof, R.3
Schaal, K.4
Eicheler, W.5
-
19
-
-
33749237751
-
High gene copy number of epidermal growth factor receptor by fluorescence in situ hybridization is frequent in head and neck squamous cell carcinomas and associates with worse recurrence-free survival
-
CHUNG CHH, ELY K, CARTER J, MCGAVRAN L, VARELLA-GARCIA M et al. High gene copy number of epidermal growth factor receptor by fluorescence in situ hybridization is frequent in head and neck squamous cell carcinomas and associates with worse recurrence-free survival. J Clin Oncol 2006; 24 (Suppl 18): 5502.
-
(2006)
J Clin Oncol
, vol.24
, Issue.SUPPL. 18
, pp. 5502
-
-
Chung, C.H.H.1
Ely, K.2
Carter, J.3
McGavran, L.4
Varella-Garcia, M.5
-
20
-
-
33749035470
-
Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting
-
SOK JC, COPPELLI FM, THOMAS SM, LANGO MN, XI S et al. Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting. Clinical Cancer Research 2006; 12: 5064-5073. http://dx.doi.org/10.1158/1078-0432.CCR-06-0913
-
(2006)
Clinical Cancer Research
, vol.12
, pp. 5064-5073
-
-
Sok, J.C.1
Coppelli, F.M.2
Thomas, S.M.3
Lango, M.N.4
Xi, S.5
-
21
-
-
21244499405
-
GAPDH as a housekeeping gene: Analysis of GAPDH mRNA expression in a panel of 72 human tissues
-
BARBER RD, HARMER DW, COLEMAN RA, CLARK BJL. GAPDH as a housekeeping gene: analysis of GAPDH mRNA expression in a panel of 72 human tissues. Physiol Genomics 2005; 21: 389-395. http://dx.doi.org/10.1152/physiolgenomics.00025.2005
-
(2005)
Physiol Genomics
, vol.21
, pp. 389-395
-
-
Barber, R.D.1
Harmer, D.W.2
Coleman, R.A.3
Clark, B.J.L.4
-
22
-
-
0142188691
-
Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme
-
SHINOJIMA N, TADA K, SHIRAISHI S, KAMIRYO T, KOCHI M et al. Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme. Cancer Res 2003; 63: 6962-6970.
-
(2003)
Cancer Res
, vol.63
, pp. 6962-6970
-
-
Shinojima, N.1
Tada, K.2
Shiraishi, S.3
Kamiryo, T.4
Kochi, M.5
-
24
-
-
33745058415
-
Pitfalls in immunohistochemical assessment of EGFR expression in soft tissue sarcomas
-
KERSTING C, PACKEISEN J, LEIDINGER B et al. Pitfalls in immunohistochemical assessment of EGFR expression in soft tissue sarcomas. J Clin Pathol 2006; 59: 585-590. http://dx.doi.org/10.1136/jcp.2005.028373
-
(2006)
J Clin Pathol
, vol.59
, pp. 585-590
-
-
Kersting, C.1
Packeisen, J.2
Leidinger, B.3
-
25
-
-
17844362179
-
Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancar: A cohort study
-
MORONI M, VERONESE S, BENVENUTI S, MARRAPESE G, SARTORE-BIANCHI A et al. Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancar: a cohort study. Lancet Oncol 2005; 6: 279-286. http://dx.doi.org/10.1016/S1470-2045(05)70102-9
-
(2005)
Lancet Oncol
, vol.6
, pp. 279-286
-
-
Moroni, M.1
Veronese, S.2
Benvenuti, S.3
Marrapese, G.4
Sartore-Bianchi, A.5
-
26
-
-
77951961432
-
Epidermal Growth Factor Receptor and K-RAS status in two cohorts of squamous cell carcinomas
-
VAN DAMME N, DERON P, VAN ROY N, DEMETTER P, BOLS A et al. Epidermal Growth Factor Receptor and K-RAS status in two cohorts of squamous cell carcinomas. BMC Cancer 2010; 10: 189-198. http://dx.doi.org/10.1186/1471-2407-10-189
-
(2010)
BMC Cancer
, vol.10
, pp. 189-198
-
-
Van Damme, N.1
Deron, P.2
Van Roy, N.3
Demetter, P.4
Bols, A.5
-
27
-
-
33748653109
-
Increased Epidermal Growth Factor Receptor Gene Copy Number Is Associated With Poor Prognosis in Head and Neck Squamous Cell Carcinomas
-
CHUNG CHH, ELY K, MCGAVRAN L, VARELLA-GARCIA M, PARKER J et al. Increased Epidermal Growth Factor Receptor Gene Copy Number Is Associated With Poor Prognosis in Head and Neck Squamous Cell Carcinomas. Journal of Clinical Oncology 2006; 24: 4170-4176. http://dx.doi.org/10.1200/JCO.2006.07.2587
-
(2006)
Journal of Clinical Oncology
, vol.24
, pp. 4170-4176
-
-
Chung, C.H.H.1
Ely, K.2
McGavran, L.3
Varella-Garcia, M.4
Parker, J.5
-
28
-
-
0142119289
-
Epidermal growth factor receptor in non-small-cell lung carcinomas: Correlation between gene copy number and protein expression and impact on prognosis
-
HIRSCH FR, VARELLA-GARCIA M, BUNN PA JR, DI MARIA MV, VEVE R et al. Epidermal growth factor receptor in non-small-cell lung carcinomas: Correlation between gene copy number and protein expression and impact on prognosis. J Clin Oncol 2003; 21: 3798-3807. http://dx.doi.org/10.1200/JCO.2003.11.069
-
(2003)
J Clin Oncol
, vol.21
, pp. 3798-3807
-
-
Hirsch, F.R.1
Varella-Garcia, M.2
Bunn Jr., P.A.3
Di Maria, M.V.4
Veve, R.5
-
29
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
PAEZ JG, JANNE PA, LEE JC, TRACY S, GREULICH H et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004; 304: 1497-1500. http://dx.doi.org/10.1126/science.1099314
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
-
30
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of nonsmall-cell lung cancer to gefitinib
-
LYNCH TJ, BELL DW, SORDELLA R, GURUBHAGVATULA S, OKIMOTO RA. Activating mutations in the epidermal growth factor receptor underlying responsiveness of nonsmall-cell lung cancer to gefitinib. N Engl J Med 2004; 350: 2129-2139. http://dx.doi.org/10.1056/NEJMoa040938
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagvatula, S.4
Okimoto, R.A.5
-
31
-
-
70350661090
-
Prevalence of K-RAS codon 12 mutations in locally advanced head and neck squamous cell carcinoma and influence with regards to response to chemoradiation therapy
-
Abstr 17008
-
BISSADA E, ABOU-CHACRA Z, WENG X, GUERTIN P, NGUYEN-TAN M et al. Prevalence of K-RAS codon 12 mutations in locally advanced head and neck squamous cell carcinoma and influence with regards to response to chemoradiation therapy. J Clin Oncol, Meeting Proceedings 2008; 26: Abstr 17008.
-
(2008)
J Clin Oncol, Meeting Proceedings
, vol.26
-
-
Bissada, E.1
Abou-Chacra, Z.2
Weng, X.3
Guertin, P.4
Nguyen-Tan, M.5
-
32
-
-
49749113623
-
Expression and mutation analysis of epidermal growth factor receptor in head and neck squamous cell carcinoma
-
SHEIKH ALI MAL, GUNDUZ M, NAGATSUKA H, GUNDUZ E, CENGIZ B et al. Expression and mutation analysis of epidermal growth factor receptor in head and neck squamous cell carcinoma. Cancer Sci 2008; 99: 1589-1594. http://dx.doi.org/10.1111/j.1349-7006.2008.00861.x
-
(2008)
Cancer Sci
, vol.99
, pp. 1589-1594
-
-
Sheikh Ali, M.A.L.1
Gunduz, M.2
Nagatsuka, H.3
Gunduz, E.4
Cengiz, B.5
-
33
-
-
0037115610
-
Amplification of Wild-Type K-ras Promotes Growth of Head and Neck Squamous Cell Carcinoma
-
HOA M, DAVIS SL, AMES SJ, SPANJAARD RA. Amplification of Wild-Type K-ras Promotes Growth of Head and Neck Squamous Cell Carcinoma. Cancer Res 2002; 62: 7154-7156.
-
(2002)
Cancer Res
, vol.62
, pp. 7154-7156
-
-
Hoa, M.1
Davis, S.L.2
Ames, S.J.3
Spanjaard, R.A.4
-
34
-
-
33646716077
-
Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors
-
JI H, ZHAO X, YUZA Y, et al. Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors. Proc Natl Acad Sci USA 2006;103: 7817-7822. http://dx.doi.org/10.1073/pnas.0510284103
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 7817-7822
-
-
Ji, H.1
Zhao, X.2
Yuza, Y.3
-
35
-
-
79951952444
-
The association between EGFR variant III, HPV, p16, c-MET, EGFR gene copy number and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of the head and neck
-
CHAU NG, PEREZ-ORDONEZ B, ZHANG K, PHAM N, JAMES HO J et al. The association between EGFR variant III, HPV, p16, c-MET, EGFR gene copy number and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of the head and neck. Head & Neck Oncology 2011; 3: 1-11.
-
(2011)
Head & Neck Oncology
, vol.3
, pp. 1-11
-
-
Chau, N.G.1
Perez-Ordonez, B.2
Zhang, K.3
Pham, N.4
James Ho, J.5
-
36
-
-
10944269712
-
Gefitinib (lressa) in oncogen-adddictive cancers and therapy for common cancers
-
BLAGOSKLONNY, M V. Gefitinib (lressa) in oncogen-adddictive cancers and therapy for common cancers. Cancer Biol Ther 2004; 3: 436-440. http://dx.doi.org/10.4161/cbt.3.5.984
-
(2004)
Cancer Biol Ther
, vol.3
, pp. 436-440
-
-
Blagosklonny, M.V.1
|