Expression and mutation analysis of epidermal growth factor receptor in head and neck squamous cell carcinoma

Cancer Science

Volumn 99, Issue 8, 2008, Pages 1589-1594

  Sheikh Ali, Mahmoud A L ^a   Gunduz, Mehmet ^a,c   Nagatsuka, Hitoshi ^a   Gunduz, Esra ^a,b   Cengiz, Beyhan ^a   Fukushima, Kunihiro ^a   Beder, Levent Bekir ^c   Demircan, Kadir ^a   Fujii, Masae ^a   Yamanaka, Noboru ^c   Shimizu, Kenji ^b   Grenman, Reidar ^d   Nagai, Noriyuki ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

^c WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^d TURKU UNIVERSITY HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; K RAS PROTEIN;

ADULT; ARTICLE; CANCER STAGING; DISEASE FREE SURVIVAL; ETHNICITY; EXON; FEMALE; GENE MUTATION; GENE OVEREXPRESSION; GENE SEQUENCE; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; HYPOPHARYNX CARCINOMA; IMMUNOHISTOCHEMISTRY; JAPANESE; LARYNX CARCINOMA; MAJOR CLINICAL STUDY; MALE; MOUTH CARCINOMA; MUTATIONAL ANALYSIS; OROPHARYNX CARCINOMA; OVERALL SURVIVAL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SQUAMOUS CELL CARCINOMA; TUMOR DIFFERENTIATION;

AGED; CELL LINE, TUMOR; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, ERBB-2; GENES, RAS; HEAD AND NECK NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; JAPAN; MALE; MIDDLE AGED; MUTATION; NEOPLASMS, SQUAMOUS CELL; POLYMERASE CHAIN REACTION; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 49749113623     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2008.00861.x     Document Type: Article

References (25)

1. Hoffman HT, Karnell LH, Funk GF, Robinson RA, Menck HR. The national cancer data base report on cancer of the head and neck. Arch Otolaryngol Head Neck Surg 1998; 124: 951-62.
2. Cohen S, Carpenter G, King L. Epidermal growth factor receptor-protein kinase interaction: Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity. J Biol Chem 1980; 255: 4834-42.
3. Karunagaran D, Tzahar E, Beerli RR et al. ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: Implications for breast cancer. EMBO J 1996; 15: 254-64.
4. Lynch TJ, Bell DW, Sordella R et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004; 350: 2129-39.
5. Shigematsu H, Lin L, Takahashi T et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst 2005; 97: 339-46.
6. Cohen EE, Rosen F, Stadler WM et al. Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck. J Clin Oncol 2003; 21: 1980-7.
7. Fisher CJ, Gillett CE, Vojtesek B, Barnes DM, Millis RR. Problems with p53 immunohistochemical staining: The effect of fixation and variation in the methods of evaluation. Br J Cancer 1994; 69: 26-31.
8. Bauman JE, Eaton KD, Martins RG. Treatment of recurrent squamous cell carcinoma of the skin with cetuximab. Arch Dermatol 2007; 143: 889-92.
9. Milas L, Mason KA, Liao Z, Ang KK. Chemoradiotherapy: Emerging treatment improvement strategies. Head Neck 2003; 25: 152-67.
10. Fukui T, Mitsudomi T. Gefitinib and epidermal growth factor receptor gene mutation. Gan Kagaku Ryoho 2007; 34: 1168-72.
11. Gazdar AF, Shigematsu H, Herz J, Minna JD. Mutations and addiction to EGFR: The Achilles heal of lung cancers? Trends Mol Med 2004; 10: 481-6.
12. Stephens P, Hunter C, Bignell G et al. Lung cancer: Intragenic ERBB2 kinase mutations in tumors. Nature 2004; 431: 525-6.
13. Lemos-González Y, Páez de la Cadena M, Rodríguez-Berrocal FJ, Rodríguez-Piñeiro AM, Pallas E, Valverde D. Absence of activating mutations in the EGFR kinase domain in Spanish head and neck cancer patients. Tumour Biol 2007; 28: 273-9.
14. Loeffler-Ragg J, Witsch-Baumgartner M, Tzankov A et al. Low incidence of mutations in EGFR kinase domain in Caucasian patients with head and neck squamous cell carcinoma. Eur J Cancer 2006; 42: 109-11.
15. Lee JW, Soung YH, Kim SY et al. Absence of EGFR mutation in the kinase domain in common human cancers besides non-small cell lung cancer. Int J Cancer 2006; 113: 510-11.
16. Cohen EE, Lingen MW, Martin LE et al. Response of some head and neck cancers to epidermal growth factor receptor tyrosine kinase inhibitors may be linked to mutation of ERBB2 rather than EGFR. Clin Cancer Res 2005; 11: 8105-8.
17. Wang SE, Narasanna A, Perez-Torres M et al. HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors. Cancer Cell 2006; 10: 25-38.
18. Yarbrough WG, Shores C, Witsell DL, Weissler MC, Fidler ME, Gilmer TM. Ras mutations and expression in head and neck squamous cell carcinomas. Laryngoscope 1994; 104: 1337-47.
19. Das N, Majumder J, DasGupta UB. Ras gene mutations in oral cancer in eastern India. Oral Onco 2000; 36: 76-80.
20. Kusukawa J, Harada H, Shima I, Sasaguri Y, Kameyama T, Morimatsu M. The significance of epidermal growth factor receptor and matrix metalloproteinase-3 in squamous cell carcinoma of the oral cavity. Eur J Cancer B Oral Oncol 1996; 32: 217-21.
21. Katoh K, Nakanishi Y, Akimoto S, Yoshimura K et al. Correlation between laminin-5 γ2 chain expression and epidermal growth factor receptor expression and its clinicopathological significance in squamous cell carcinoma of the tongue. Oncology 2002; 62: 318-26.
22. Rubin Grandis J, Melhem MF, Gooding WE et al. Levels of TGF-α and EGFR protein in head and neck squamous cell carcinoma and patient survival. J Natl Cancer Inst 1998; 90: 799-801.
23. Ulanovski D, Stern Y, Roizman P, Shpitzer T, Popovtzer A, Feinmesser R. Expression of EGFR and Cerb-B2 as prognostic factors in cancer of the tongue. Oral Oncol 2004; 40: 532-7.
24. Reimers N, Kasper HU, Weissenborn SJ et al. Combined analysis of HPV-DNA, p16 and EGFR expression to predict prognosis in oropharyngeal cancer. Int J Cancer 2007; 120: 1731-8.
25. Smith BD, Smith GL, Carter D et al. Molecular marker expression in oral and oropharyngeal squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 2001; 127: 780-5.