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Volumn 23, Issue SUPPL. 10, 2012, Pages

Diagnostic work-up of carcinoma of unknown primary: From immunohistochemistry to molecular profiling

Author keywords

Cancer; Immunohistochemistry; Metastatic; Molecular profiling; Pathology; Unknown primary

Indexed keywords

ASPARTIC PROTEINASE; BIOLOGICAL MARKER; CYTOKERATIN 20; CYTOKERATIN 7; MESSENGER RNA; MICRORNA; NAPSIN A; OCTAMER TRANSCRIPTION FACTOR 4; THYROID TRANSCRIPTION FACTOR 1; TRANSCRIPTION FACTOR PAX8; UNCLASSIFIED DRUG;

EID: 84866763589     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mds357     Document Type: Article
Times cited : (92)

References (49)
  • 1
    • 84859625307 scopus 로고    scopus 로고
    • Cancer of unknown primary site
    • Pavlidis N, Pentheroudakis G. Cancer of unknown primary site. Lancet 2012; 379: 1428-1435.
    • (2012) Lancet , vol.379 , pp. 1428-1435
    • Pavlidis, N.1    Pentheroudakis, G.2
  • 2
    • 82555187093 scopus 로고    scopus 로고
    • Carcinomas of an unknown primary origin diagnosis and treatment
    • Massard C, Loriot Y, Fizazi K. Carcinomas of an unknown primary origin- diagnosis and treatment. Nat Rev Clin Oncol 2011; 8: 701-710.
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 701-710
    • Massard, C.1    Loriot, Y.2    Fizazi, K.3
  • 3
    • 80052724384 scopus 로고    scopus 로고
    • Cancers of unknown primary site: ESMO clinical practice guidelines for diagnosis, treatment and follow-up
    • Fizazi K, Greco FA, Pavlidis N et al. Cancers of unknown primary site: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol 2011; 22(Suppl 6): vi64-vi68.
    • (2011) Ann Oncol , vol.22 , Issue.SUPPL. 6 , pp. 664-668
    • Fizazi, K.1    Greco, F.A.2    Pavlidis, N.3
  • 4
    • 78650417605 scopus 로고    scopus 로고
    • National Institute for Health and Clinical Excellence. Metastatic Malignant Disease of Unknown Primary Origin. London: National Institute for Health and Clinical Excellence; CG104
    • National Institute for Health and Clinical Excellence. Metastatic Malignant Disease of Unknown Primary Origin: Diagnosis and Management of Metastatic Malignant Disease of Unknown Primary Origin. London: National Institute for Health and Clinical Excellence 2010; CG104.
    • (2010) Diagnosis and Management of Metastatic Malignant Disease of Unknown Primary Origin
  • 5
    • 84856339714 scopus 로고    scopus 로고
    • Cancer of unknown primary: progress in the search for improved and rapid diagnosis leading toward superior patient outcomes
    • Greco FA, Oien K, Erlander M et al. Cancer of unknown primary: progress in the search for improved and rapid diagnosis leading toward superior patient outcomes. Ann Oncol 2012; 23: 298-304.
    • (2012) Ann Oncol , vol.23 , pp. 298-304
    • Greco, F.A.1    Oien, K.2    Erlander, M.3
  • 6
    • 58549085258 scopus 로고    scopus 로고
    • Pathologic evaluation of unknown primary cancer
    • Oien KA. Pathologic evaluation of unknown primary cancer. Semin Oncol 2009; 36: 8-37.
    • (2009) Semin Oncol , vol.36 , pp. 8-37
    • Oien, K.A.1
  • 7
    • 40149096377 scopus 로고    scopus 로고
    • Undifferentiated tumor-true identity by immunohistochemistry
    • Bahrami A, Truong LD, Ro JY. Undifferentiated tumor-true identity by immunohistochemistry. Arch Pathol Lab Med 2008; 132: 326-348.
    • (2008) Arch Pathol Lab Med , vol.132 , pp. 326-348
    • Bahrami, A.1    Truong, L.D.2    Ro, J.Y.3
  • 8
    • 79958019473 scopus 로고    scopus 로고
    • A comprehensive analysis of PAX8 expression in human epithelial tumors
    • Laury AR, Perets R, Piao H et al. A comprehensive analysis of PAX8 expression in human epithelial tumors. Am J Surg Pathol 2011; 35: 816-826.
    • (2011) Am J Surg Pathol , vol.35 , pp. 816-826
    • Laury, A.R.1    Perets, R.2    Piao, H.3
  • 9
    • 84856617883 scopus 로고    scopus 로고
    • Napsin A, a new marker for lung adenocarcinoma, is complementary and more sensitive and specific than thyroid transcription factor 1 in the differential diagnosis of primary pulmonary carcinoma evaluation of 1674 cases by tissue microarray
    • Turner BM, Cagle PT, Sainz IM et al. Napsin A, a new marker for lung adenocarcinoma, is complementary and more sensitive and specific than thyroid transcription factor 1 in the differential diagnosis of primary pulmonary carcinoma evaluation of 1674 cases by tissue microarray. Arch Pathol Lab Med 2012; 136: 163-171.
    • (2012) Arch Pathol Lab Med , vol.136 , pp. 163-171
    • Turner, B.M.1    Cagle, P.T.2    Sainz, I.M.3
  • 10
    • 74549125753 scopus 로고    scopus 로고
    • An abundance of ubiquitously expressed genes revealed by tissue transcriptome sequence data
    • Ramskold D, Wang ET, Burge CB et al. An abundance of ubiquitously expressed genes revealed by tissue transcriptome sequence data. PLoS Comput Biol 2009; 5: e1000598.
    • (2009) PLoS Comput Biol , vol.5
    • Ramskold, D.1    Wang, E.T.2    Burge, C.B.3
  • 11
    • 74849106389 scopus 로고    scopus 로고
    • A taxonomy of epithelial human cancer and their metastases
    • Gevaert O, Daemen A, De Moor B et al. A taxonomy of epithelial human cancer and their metastases. BMC Med Genomics 2009; 2: 69.
    • (2009) BMC Med Genomics , vol.2 , pp. 69
    • Gevaert, O.1    Daemen, A.2    De Moor, B.3
  • 12
    • 76149112585 scopus 로고    scopus 로고
    • Determining tissue of origin for metastatic cancers: meta-analysis and literature review of immunohistochemistry performance
    • Anderson GG, Weiss LM. Determining tissue of origin for metastatic cancers: meta-analysis and literature review of immunohistochemistry performance. Appl Immunohistochem Mol Morphol 2010; 18: 3-8.
    • (2010) Appl Immunohistochem Mol Morphol , vol.18 , pp. 3-8
    • Anderson, G.G.1    Weiss, L.M.2
  • 13
    • 66349093950 scopus 로고    scopus 로고
    • Multicenter Validation of a 1,550-Gene Expression Profile for Identification of Tumor Tissue of Origin
    • Monzon FA, Lyons-Weiler M, Buturovic LJ et al. Multicenter Validation of a 1,550-Gene Expression Profile for Identification of Tumor Tissue of Origin. J Clin Oncol 2009; 27: 2503-2508.
    • (2009) J Clin Oncol , vol.27 , pp. 2503-2508
    • Monzon, F.A.1    Lyons-Weiler, M.2    Buturovic, L.J.3
  • 14
    • 77954366543 scopus 로고    scopus 로고
    • Hybrid model integrating immunohistochemistry and expression profiling for the classification of carcinomas of unknown primary site
    • Centeno BA, Bloom G, Chen DT et al. Hybrid model integrating immunohistochemistry and expression profiling for the classification of carcinomas of unknown primary site. J Mol Diagn 2010; 12: 476-486.
    • (2010) J Mol Diagn , vol.12 , pp. 476-486
    • Centeno, B.A.1    Bloom, G.2    Chen, D.T.3
  • 15
    • 84856386227 scopus 로고    scopus 로고
    • Immunohistochemical profile for unknown primary adenocarcinoma
    • Hashimoto K, Sasajima Y, Ando M et al. Immunohistochemical profile for unknown primary adenocarcinoma. PLoS One 2012; 7: e31181.
    • (2012) PLoS One , vol.7
    • Hashimoto, K.1    Sasajima, Y.2    Ando, M.3
  • 16
    • 77955171924 scopus 로고    scopus 로고
    • NKX3 1 as a marker of prostatic origin in metastatic tumors
    • Gurel B, Ali TZ, Montgomery EA et al. NKX3.1 as a marker of prostatic origin in metastatic tumors. Am J Surg Pathol 2010; 34: 1097-1105.
    • (2010) Am J Surg Pathol , vol.34 , pp. 1097-1105
    • Gurel, B.1    Ali, T.Z.2    Montgomery, E.A.3
  • 17
    • 78650804445 scopus 로고    scopus 로고
    • Can we tell the site of origin of metastatic squamous cell carcinoma? An immunohistochemical tissue microarray study of 194 cases
    • Pereira TC, Share SM, Magalhaes AV et al. Can we tell the site of origin of metastatic squamous cell carcinoma? An immunohistochemical tissue microarray study of 194 cases. Appl Immunohistochem Mol Morphol 2011; 19: 10-14.
    • (2011) Appl Immunohistochem Mol Morphol , vol.19 , pp. 10-14
    • Pereira, T.C.1    Share, S.M.2    Magalhaes, A.V.3
  • 18
    • 84877585621 scopus 로고    scopus 로고
    • Blinded comparator study of immunohistochemistry (IC) versus a 92-gene cancer classifier in the diagnosis of primary site in metastatic tumors
    • Weiss LM, Chu PG, Schroeder BE et al. Blinded comparator study of immunohistochemistry (IC) versus a 92-gene cancer classifier in the diagnosis of primary site in metastatic tumors. J Clin Oncol 2012; 30: e21019.
    • (2012) J Clin Oncol , vol.30
    • Weiss, L.M.1    Chu, P.G.2    Schroeder, B.E.3
  • 19
    • 84877581138 scopus 로고    scopus 로고
    • Pathological diagnoses in cases of indeterminate or unknown primary submitted for molecular tumor profiling
    • Schroeder BE, Laouri M, Chen E et al. Pathological diagnoses in cases of indeterminate or unknown primary submitted for molecular tumor profiling. Lab Invest 2012; 92: 105A-106A.
    • (2012) Lab Invest , vol.92
    • Schroeder, B.E.1    Laouri, M.2    Chen, E.3
  • 20
    • 80755141968 scopus 로고    scopus 로고
    • Performance and clinical evaluation of the 92-gene real-time PCR assay for tumor classification
    • Erlander MG, Ma X-J, Kesty NC et al. Performance and clinical evaluation of the 92-gene real-time PCR assay for tumor classification. J Mol Diagn 2011; 13: 493-503.
    • (2011) J Mol Diagn , vol.13 , pp. 493-503
    • Erlander, M.G.1    Ma, X.-J.2    Kesty, N.C.3
  • 21
    • 84866745723 scopus 로고    scopus 로고
    • Molecular tumor profiling in the diagnosis of patients with carcinoma of unknown primary site: retrospective evaluation of gene microarray assay
    • Hainsworth JD, Pillai R, Henner WD et al. Molecular tumor profiling in the diagnosis of patients with carcinoma of unknown primary site: retrospective evaluation of gene microarray assay. J Mol Biomarkers Diagn 2011; 2: 106.
    • (2011) J Mol Biomarkers Diagn , vol.2 , pp. 106
    • Hainsworth, J.D.1    Pillai, R.2    Henner, W.D.3
  • 22
    • 21044444707 scopus 로고    scopus 로고
    • Markers of adenocarcinoma characteristic of the site of origin: development of a diagnostic algorithm
    • Dennis JL, Hvidsten TR, Wit EC et al. Markers of adenocarcinoma characteristic of the site of origin: development of a diagnostic algorithm. Clin Cancer Res 2005; 11: 3766-3772.
    • (2005) Clin Cancer Res , vol.11 , pp. 3766-3772
    • Dennis, J.L.1    Hvidsten, T.R.2    Wit, E.C.3
  • 23
    • 78651080394 scopus 로고    scopus 로고
    • Validation and reproducibility of a microarraybased gene expression test for tumor identification in formalin-fixed, paraffinembedded specimens
    • Pillai R, Deeter R, Rigl CT et al. Validation and reproducibility of a microarraybased gene expression test for tumor identification in formalin-fixed, paraffinembedded specimens. J Mol Diagn 2011; 13: 48-56.
    • (2011) J Mol Diagn , vol.13 , pp. 48-56
    • Pillai, R.1    Deeter, R.2    Rigl, C.T.3
  • 24
    • 84862869591 scopus 로고    scopus 로고
    • A second-generation microRNA-based assay for diagnosing tumor tissue origin
    • Meiri E, Mueller WC, Rosenwald S et al. A second-generation microRNA-based assay for diagnosing tumor tissue origin. Oncologist 2012; 17: 801-812.
    • (2012) Oncologist , vol.17 , pp. 801-812
    • Meiri, E.1    Mueller, W.C.2    Rosenwald, S.3
  • 25
    • 79960948113 scopus 로고    scopus 로고
    • Gene-expression assays and personalized cancer care: tissue-of-origin test for cancer of unknown primary origin
    • Takei H, Monzon FA. Gene-expression assays and personalized cancer care: tissue-of-origin test for cancer of unknown primary origin. Pers Med 2011; 8: 429-436.
    • (2011) Pers Med , vol.8 , pp. 429-436
    • Takei, H.1    Monzon, F.A.2
  • 26
    • 76449096120 scopus 로고    scopus 로고
    • Diagnosis of metastatic neoplasms: molecular approaches for identification of tissue of origin
    • Monzon FA, Koen TJ. Diagnosis of metastatic neoplasms: molecular approaches for identification of tissue of origin. Arch Pathol Lab Med 2010; 134: 216-224.
    • (2010) Arch Pathol Lab Med , vol.134 , pp. 216-224
    • Monzon, F.A.1    Koen, T.J.2
  • 27
    • 83755178031 scopus 로고    scopus 로고
    • Gene expression analysis and immunohistochemistry in evaluation of cancer of unknown primary: time for a patient-centered approach
    • Handorf CR. Gene expression analysis and immunohistochemistry in evaluation of cancer of unknown primary: time for a patient-centered approach. J Natl Compr Cancer Netw 2011; 9: 1415-1420.
    • (2011) J Natl Compr Cancer Netw , vol.9 , pp. 1415-1420
    • Handorf, C.R.1
  • 28
    • 58549117539 scopus 로고    scopus 로고
    • Molecular classification of unknown primary cancer
    • Bender RA, Erlander MG. Molecular classification of unknown primary cancer. Semin Oncol 2009; 36: 38-43.
    • (2009) Semin Oncol , vol.36 , pp. 38-43
    • Bender, R.A.1    Erlander, M.G.2
  • 29
    • 74749093838 scopus 로고    scopus 로고
    • Diagnosis of uncertain primary tumors with the pathwork tissue-of-origin test
    • Monzon FA, Dumur CI. Diagnosis of uncertain primary tumors with the pathwork tissue-of-origin test. Expert Rev Mol Diagn 2010; 10: 17-25.
    • (2010) Expert Rev Mol Diagn , vol.10 , pp. 17-25
    • Monzon, F.A.1    Dumur, C.I.2
  • 30
    • 82655171619 scopus 로고    scopus 로고
    • Clinical verification of the performance of the pathwork tissue of origin test: utility and limitations
    • Dumur CI, Fuller CE, Blevins TL et al. Clinical verification of the performance of the pathwork tissue of origin test: utility and limitations. Am J Clin Pathol 2011; 136: 924-933.
    • (2011) Am J Clin Pathol , vol.136 , pp. 924-933
    • Dumur, C.I.1    Fuller, C.E.2    Blevins, T.L.3
  • 31
    • 84859791018 scopus 로고    scopus 로고
    • Identification of tissue of origin in body fluid specimens using a gene expression microarray assay
    • Stancel GA, Coffey D, Alvarez K et al. Identification of tissue of origin in body fluid specimens using a gene expression microarray assay. Cancer Cytopathol 2012; 120: 62-70.
    • (2012) Cancer Cytopathol , vol.120 , pp. 62-70
    • Stancel, G.A.1    Coffey, D.2    Alvarez, K.3
  • 32
    • 79956307545 scopus 로고    scopus 로고
    • Gene expression profiling from formalin-fixed, paraffin-embedded tissue for tumor diagnosis
    • Grenert JP, Smith A, Ruan W et al. Gene expression profiling from formalin-fixed, paraffin-embedded tissue for tumor diagnosis. Clin Chim Acta 2011; 412: 1462-1464.
    • (2011) Clin Chim Acta , vol.412 , pp. 1462-1464
    • Grenert, J.P.1    Smith, A.2    Ruan, W.3
  • 33
    • 84863911666 scopus 로고    scopus 로고
    • Multisite Validation Study To Determine Performance Characteristics of a 92-gene Molecular Cancer Classifier
    • Kerr SE, Schnabel CA, Sullivan PS et al. Multisite Validation Study To Determine Performance Characteristics of a 92-gene Molecular Cancer Classifier. Clin Cancer Res 2012; 18: 3592-3960.
    • (2012) Clin Cancer Res , vol.18 , pp. 3592-3960
    • Kerr, S.E.1    Schnabel, C.A.2    Sullivan, P.S.3
  • 34
    • 84877582175 scopus 로고    scopus 로고
    • Use of a 92-gene molecular classifier to predict the site of origin for primary and metastatic tumors with neuroendocrine differentiation
    • Kerr SE, Schnabel CA, Sullivan PS et al. Use of a 92-gene molecular classifier to predict the site of origin for primary and metastatic tumors with neuroendocrine differentiation. Lab Invest 2012; 92: 147A.
    • (2012) Lab Invest , vol.92
    • Kerr, S.E.1    Schnabel, C.A.2    Sullivan, P.S.3
  • 35
    • 77952607898 scopus 로고    scopus 로고
    • Molecular profiling in unknown primary cancer: accuracy of tissue of origin prediction
    • Greco FA, Spigel DR, Yardley DA et al. Molecular profiling in unknown primary cancer: accuracy of tissue of origin prediction. Oncologist 2010; 15: 500-506.
    • (2010) Oncologist , vol.15 , pp. 500-506
    • Greco, F.A.1    Spigel, D.R.2    Yardley, D.A.3
  • 36
    • 84877584760 scopus 로고    scopus 로고
    • A novel microRNA-based test demonstrate above 90% accuracy in classification of metastatic tumors from patients diagnosed with carcinoma of unknown primary
    • Sanden M, Pentheroudakis G, St Cyr B et al. A novel microRNA-based test demonstrate above 90% accuracy in classification of metastatic tumors from patients diagnosed with carcinoma of unknown primary. Lab Invest 2012; 92: 456A.
    • (2012) Lab Invest , vol.92
    • Sanden, M.1    Pentheroudakis, G.2    St Cyr, B.3
  • 37
    • 79959668461 scopus 로고    scopus 로고
    • Evaluation of a gene expression microarray-based assay to determine tissue type of origin on a diverse set of 49 malignancies
    • Beck AH, Rodriguez-Paris J, Zehnder J et al. Evaluation of a gene expression microarray-based assay to determine tissue type of origin on a diverse set of 49 malignancies. Am J Surg Pathol 2011; 35: 1030-1037.
    • (2011) Am J Surg Pathol , vol.35 , pp. 1030-1037
    • Beck, A.H.1    Rodriguez-Paris, J.2    Zehnder, J.3
  • 38
    • 33645779944 scopus 로고    scopus 로고
    • Molecular classification of human cancers using a 92-gene real-time quantitative polymerase chain reaction assay
    • Ma XJ, Patel R, Wang XQ et al. Molecular classification of human cancers using a 92-gene real-time quantitative polymerase chain reaction assay. Arch Pathol Lab Med 2006; 130: 465-473.
    • (2006) Arch Pathol Lab Med , vol.130 , pp. 465-473
    • Ma, X.J.1    Patel, R.2    Wang, X.Q.3
  • 39
    • 84866768248 scopus 로고    scopus 로고
    • Clinical utility of geneexpression profiling for tumor-site origin in patients with metastatic or poorly differentiated cancer: impact on diagnosis, treatment, and survival
    • Nystrom SJ, Hornberger JC, Varadhachary GR et al. Clinical utility of geneexpression profiling for tumor-site origin in patients with metastatic or poorly differentiated cancer: impact on diagnosis, treatment, and survival. Oncotarget 2012; 3: 620-628.
    • (2012) Oncotarget , vol.3 , pp. 620-628
    • Nystrom, S.J.1    Hornberger, J.C.2    Varadhachary, G.R.3
  • 40
    • 80755189414 scopus 로고    scopus 로고
    • Potential clinical utility of geneexpression profiling in identifying tumors of uncertain origin
    • Laouri M, Halks-Miller M, Henner WD et al. Potential clinical utility of geneexpression profiling in identifying tumors of uncertain origin. Pers Med 2011; 8: 615-622.
    • (2011) Pers Med , vol.8 , pp. 615-622
    • Laouri, M.1    Halks-Miller, M.2    Henner, W.D.3
  • 41
    • 84860747285 scopus 로고    scopus 로고
    • A retrospective study of treatment outcomes in patients with carcinoma of unknown primary site and a colorectal cancer molecular profile
    • Hainsworth JD, Schnabel CA, Erlander MG et al. A retrospective study of treatment outcomes in patients with carcinoma of unknown primary site and a colorectal cancer molecular profile. Clin Colorectal Cancer 2012; 11: 112-118.
    • (2012) Clin Colorectal Cancer , vol.11 , pp. 112-118
    • Hainsworth, J.D.1    Schnabel, C.A.2    Erlander, M.G.3
  • 42
    • 84866774940 scopus 로고    scopus 로고
    • Molecular gene expression profiling to predict the tissue of origin and direct site-specific therapy in patients (pts) with carcinoma of unknown primary site (CUP): results of a prospective Sarah Cannon Research Institute (SCRI) trial
    • Greco FA, Rubin MS, Boccia RV et al. Molecular gene expression profiling to predict the tissue of origin and direct site-specific therapy in patients (pts) with carcinoma of unknown primary site (CUP): results of a prospective Sarah Cannon Research Institute (SCRI) trial. J Clin Oncol 2012; 42: e10530.
    • (2012) J Clin Oncol , vol.42
    • Greco, F.A.1    Rubin, M.S.2    Boccia, R.V.3
  • 43
    • 20144377712 scopus 로고    scopus 로고
    • An expression-based site of origin diagnostic method designed for clinical application to cancer of unknown origin
    • Tothill RW, Kowalczyk A, Rischin D et al. An expression-based site of origin diagnostic method designed for clinical application to cancer of unknown origin. Cancer Res 2005; 65: 4031-4040.
    • (2005) Cancer Res , vol.65 , pp. 4031-4040
    • Tothill, R.W.1    Kowalczyk, A.2    Rischin, D.3
  • 44
    • 79960905671 scopus 로고    scopus 로고
    • MicroRNA profiling for the identification of cancers with unknown primary tissue-of-origin
    • Ferracin M, Pedriali M, Veronese A et al. MicroRNA profiling for the identification of cancers with unknown primary tissue-of-origin. J Pathol 2011; 225: 43-53.
    • (2011) J Pathol , vol.225 , pp. 43-53
    • Ferracin, M.1    Pedriali, M.2    Veronese, A.3
  • 45
    • 84856555311 scopus 로고    scopus 로고
    • A DNA methylation fingerprint of 1628 human samples
    • Fernandez AF, Assenov Y, Martin-Subero JI et al. A DNA methylation fingerprint of 1628 human samples. Genome Res 2012; 22: 407-419.
    • (2012) Genome Res , vol.22 , pp. 407-419
    • Fernandez, A.F.1    Assenov, Y.2    Martin-Subero, J.I.3
  • 46
    • 33746028189 scopus 로고    scopus 로고
    • A quantitative reverse transcriptasepolymerase chain reaction assay to identify metastatic carcinoma tissue of origin
    • Talantov D, Baden J, Jatkoe T et al. A quantitative reverse transcriptasepolymerase chain reaction assay to identify metastatic carcinoma tissue of origin. J Mol Diagn 2006; 8: 320-329.
    • (2006) J Mol Diagn , vol.8 , pp. 320-329
    • Talantov, D.1    Baden, J.2    Jatkoe, T.3
  • 47
    • 52449084470 scopus 로고    scopus 로고
    • Molecular profiling of carcinoma of unknown primary and correlation with clinical evaluation
    • Varadhachary GR, Talantov D, Raber MN et al. Molecular profiling of carcinoma of unknown primary and correlation with clinical evaluation. J Clin Oncol 2008; 26: 4442-4448.
    • (2008) J Clin Oncol , vol.26 , pp. 4442-4448
    • Varadhachary, G.R.1    Talantov, D.2    Raber, M.N.3
  • 48
    • 82255162734 scopus 로고    scopus 로고
    • Classification of unknown primary tumors with a data-driven method based on a large microarray reference database
    • Ojala KA, Kilpinen SK, Kallioniemi OP. Classification of unknown primary tumors with a data-driven method based on a large microarray reference database. Genome Med 2011; 3: 63.
    • (2011) Genome Med , vol.3 , pp. 63
    • Ojala, K.A.1    Kilpinen, S.K.2    Kallioniemi, O.P.3
  • 49
    • 70350697843 scopus 로고    scopus 로고
    • ISOLATE: a computational strategy for identifying the primary origin of cancers using high-throughput sequencing
    • Quon G, Morris Q. ISOLATE: a computational strategy for identifying the primary origin of cancers using high-throughput sequencing. Bioinformatics 2009; 25: 2882-2889.
    • (2009) Bioinformatics , vol.25 , pp. 2882-2889
    • Quon, G.1    Morris, Q.2


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