Gamma delta (γδ) T-cells are critical in the up-regulation of inducible nitric oxide synthase at the burn wound site

Cytokine

Volumn 60, Issue 2, 2012, Pages 528-534

  Oppeltz, Richard F ^a   Rani, Meenakshi ^a   Zhang, Qiong ^a   Schwacha, Martin G ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

Chemokines; Cytokines; Inflammation; INOS; Trauma

Indexed keywords

CELL PROTEIN; GRANULOCYTE COLONY STIMULATING FACTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN KC; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BURN; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; ENZYME ACTIVITY; ENZYME INHIBITION; GAMMA DELTA T LYMPHOCYTE; INFLAMMATION; LYMPHOCYTE FUNCTION; MALE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN INJURY; UPREGULATION; WOUND HEALING;

ANIMALS; BURNS; CHEMOKINES; MALE; MICE; MICE, INBRED C57BL; NITRIC OXIDE SYNTHASE TYPE II; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; SKIN; UP-REGULATION; WOUND HEALING;

MUS;

EID: 84866749104     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2012.07.003     Document Type: Article

References (43)

1. Schwacha M.G., Nickel E., Daniel T. Burn injury-induced alterations in wound inflammation and healing are associated with suppressed hypoxia inducible factor-1alpha expression. Mol Med 2008, 14:628-633.
2. Oliveira G.V., Shimoda K., Enkhbaatar P., Jodoin J., Burke A.S., Chinkes D.L., et al. Skin nitric oxide and its metabolites are increased in nonburned skin after thermal injuries. Shock 2004, 22:278-282.
3. Zhu H., Wei X., Bian K., Murad F. Effects of nitric oxide on skin burn wound healing. J Burn Care Res 2008, 29:804-814.
4. Curran J.N., Winter D.C., Bouchier-Hayes D. Biological fate and clinical implications of arginine metabolism in tissue healing. Wound Repair Regen 2006, 14:376-386.
5. Moncada S., Palmer R.M., Higgs E.A. Nitric oxide; physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991, 43:109-142.
6. Gamelli R.L., George M., Sharp-Pucci M., Dries D.J., Radisazljevic Z. Burn-induced nitric oxide release in humans. J. Trauma 1995, 39:869-878.
7. Daniel T., Alexander M., Hubbard W.J., Chaudry I.H., Choudhry M.A., Schwacha M.G. Nitric oxide contributes to the development of a post-injury Th2 T-cell phenotype and immune dysfunction. J. Cell. Physiol. 2006, 208:418-427.
8. Soejima K., Traber L.D., Schmalstieg F.C., Hawkins H., Jodoin J.M., Szabo C., et al. Role of nitric oxide in vascular permeability after combined burns and smoke inhalation injury. Am J Respir Crit Care Med 2001, 163:745-752.
9. Chen L.W., Hsu C.M., Cha M.C., Chen J.S., Chen S.C. Changes in gut mucosal nitric oxide synthase (NOS) activity after thermal injury and its relation with barrier failure. Shock 1999, 11:104-110.
10. Chen L.W., Hsu C.M., Wang J.S., Chen H.L., Chen J.S. Inhibition of inducible nitric oxide synthase (iNOS) prevents lung neutrophil deposition and damage in burned rats. Shock 2001, 15:151-156.
11. Schwacha M.G., Somers S.D. Thermal injury induced immunosuppression in mice: the role of macrophage derived reactive nitrogen intermediates. J Leuko Biol 1998, 63:51-58.
12. 2: contribution to the enhancement of inducible nitric oxide synthase activity. J Leuko Biol 1998, 64:740-746.
13. Bamberger T., Masson I., Mathieu J., Chauvelot-Moachon L., Giroud J.P. Nitric oxide mediates the depression of lymphoproliferative responses following burn injury in rats. Biomed Pharmacother 1992, 46:445-450.
14. Masson I., Mathieu J., Nolland X.B., Sousa M.D., Chanaud B., Stralko S., et al. Role of nitric oxide in depressed lymphproliferative responses and altered cytokine production following thermal injury in rats. Cell Immunol 1998, 186:121-132.
15. Inoue H., Ando K., Wakisaka N., Matsuzaki K., Aihara M., Kumagai N. Effects of nitric oxide synthase inhibitors on vascular hyperpermeability with thermal injury in mice. Nitric Oxide 2001, 5:334-342.
16. Paulsen S.M., Wurster S.H., Nanney L.B. Expression of inducible nitric oxide synthase in human burn wounds. Wound Repair Regen 1998, 6:142-148.
17. Rawlingson A., Shendi K., Greenacre S.A., England T.G., Jenner A.M., Poston R.N., et al. Functional significance of inducible nitric oxide synthase induction and protein nitration in the thermally injured cutaneous microvasculature. Am J Pathol 2003, 162:1373-1380.
18. Stallmeyer B., Kampfer H., Kolb N., Pfeilschifter J., Frank S. The function of nitric oxide in wound repair: inhibition of inducible nitric oxide-synthase severely impairs wound reepithelialization. J. Invest. Dermatol. 1999, 113:1090-1098.
19. Yamasaki K., Edington H.D., McClosky C., Tzeng E., Lizonova A., Kovesdi I., et al. Reversal of impaired wound repair in iNOS-deficient mice by topical adenoviral-mediated iNOS gene transfer. J Clin Invest 1998, 101:967-971.
20. Daniel T., Thobe B.M., Chaudry I.H., Choudhry M.A., Hubbard W.J., Schwacha M.G. Regulation of the postburn wound inflammatory response by gamma delta T-cells. Shock 2007, 28:278-283.
21. Alexander M., Daniel T., Chaudry I.H., Choudhry M., Schwacha M.G. T-cells of the γδ T-cell receptor lineage play an important role in the post burn wound healing process. J Burn Care Res 2006, 27:18-25.
22. Schneider D.F., Glenn C.H., Faunce D.E. Innate lymphocyte subsets and their immunoregulatory roles in burn injury and sepsis. J Burn Care Res 2007, 28:365-379.
23. Schwacha M.G. Gamma delta T-cells: potential regulators of the post-burn inflammatory response. Burns 2009, 35:318-326.
24. Jameson J., Havran W.L. Skin gamma delta T-cell functions in homeostasis and wound healing. Immunol Rev 2007, 215:114-122.
25. Jones-Carson J., Vazquez-Torres A., van der Heyde H.C., Warner T., Wagner R.D., Balish E. Gamma delta T cell-induced nitric oxide production enhances resistance to mucosal candidiasis. Nat Med 1995, 1:552-557.
26. Sasaki J.R., Zhang Q., Schwacha M.G. Burn induces a Th-17 inflammatory response at the injury site. Burns 2011, 37:646-651.
27. Schwacha M.G., Knoferl M.W., Chaudry I.H. Does burn wound excision after thermal injury attenuate subsequent macrophage hyperactivity and immunosuppression?. Shock 2000, 14:623-628.
28. Badn W., Hegardt P., Fellert M.A., Darabi A., Esbjornsson M., Smith K.E., et al. Inhibition of inducible nitric oxide synthase enhances anti-tumour immune responses in rats immunized with IFN-gamma-secreting glioma cells. Scand J Immunol 2007, 65:289-297.
29. Zhu H., Ka B., Murad F. Nitric oxide accelerates the recovery from burn wounds. World J Surg 2007, 31:624-631.
30. Isenberg J.S., Ridnour L.A., Espey M.G., Wink D.A., Roberts D.D. Nitric oxide in wound-healing. Microsurgery 2005, 25:442-451.
31. Lowenstein C.J., Padalko E. INOS (NOS2) at a glance. J Cell Sci 2004, 117:2865-2867.
32. Aktan F. INOS-mediated nitric oxide production and its regulation. Life Sci 2004, 75:639-653.
33. Kibbe M., Billiar T., Tzeng E. Inducible nitric oxide synthase and vascular injury. Cardiovasc Res 1999, 43:650-657.
34. Augustin A., Kubo R.T., Sim G.K. Resident pulmonary lymphocytes expressing the gamma/delta T-cell receptor. Nature 1989, 340:239-241.
35. Hayday A.C. [gamma][delta] cells: a right time and a right place for a conserved third way of protection. Annu Rev Immunol 2000, 18:975-1026.
36. Schwacha M.G. Macrophages and post-burn immune dysfunction. Burns 2003, 29:1-14.
37. Havran W.L., Jameson J.M. Epidermal T cells and wound healing. J Immunol 2010, 184:5423-5428.
38. Witte M.B., Barbul A. Role of nitric oxide in wound repair. Am J Surg 2002, 183:406-412.
39. Lee R.H., Efron D., Tantry U., Barbul A. Nitric oxide in the healing wound: a time-course study. J Surg Res 2001, 101:104-108.
40. Schwacha M.G., Thobe B.M., Daniel T., Hubbard W.J. Impact of thermal injury on wound infiltration and the dermal inflammatory response. J Surg Res 2010, 158:112-120.
41. Kane A.J., Barker J.E., Mitchell G.M., Theile D.R., Romero R., Messina A., et al. Inducible nitric oxide synthase (iNOS) activity promotes ischaemic skin flap survival. Brit J Pharmacol 2001, 132:1631-1638.
42. Naura A.S., Zerfaoui M., Kim H., Abd Elmageed Z.Y., Rodriguez P.C., Hans C.P., et al. Requirement for inducible nitric oxide synthase in chronic allergen exposure-induced pulmonary fibrosis but not inflammation. J Immunol 2010, 185:3076-3085.
43. Hamada T., Duarte S., Tsuchihashi S., Busuttil R.W., Coito A.J. Inducible nitric oxide synthase deficiency impairs matrix metalloproteinase-9 activity and disrupts leukocyte migration in hepatic ischemia/reperfusion injury. Am J Pathol 2009, 174:2265-2277.