Targeted inactivation of transcription factors by overexpression of their truncated forms in plants

Plant Journal

Volumn 72, Issue 1, 2012, Pages 162-172

  Seo, Pil Joon ^a   Hong, Shin Young ^a   Ryu, Jae Yong ^a   Jeong, Eun Young ^a   Kim, Sang Gyu ^b   Baldwin, Ian T ^b   Park, Chung Mo ^a,c  

^a Seoul National University   (South Korea)

^b MAX PLANCK INSTITUTE FOR CHEMICAL ECOLOGY   (Germany)

^c Seoul National University   (South Korea)

Author keywords

Arabidopsis; artificial siPEP; Brachypodium; peptide interference (PEPi); technical advance; transcription factor

Indexed keywords

AGRICULTURAL BIOTECHNOLOGY; ARABIDOPSIS; ARTIFICIAL SIPEP; BRACHYPODIUM; CONSTANS; CROP PLANTS; DNA-BINDING; ENVIRONMENTAL ADAPTABILITY; GENE INACTIVATION; GENE REGULATORY NETWORKS; MADS-BOX; MYB TRANSCRIPTION FACTORS; NUCLEAR IMPORT; OVER-EXPRESSION; PLANT DEVELOPMENT; PROTEIN DOMAINS; TECHNICAL ADVANCES; TRANSGENIC PLANTS;

GENES; PEPTIDES;

TRANSCRIPTION FACTORS;

AGL20 PROTEIN, ARABIDOPSIS; ARABIDOPSIS AGAMOUS PROTEIN; ARABIDOPSIS PROTEIN; DNA BINDING PROTEIN; LHY PROTEIN, ARABIDOPSIS; MADS DOMAIN PROTEIN; PEPTIDE; TRANSCRIPTION FACTOR; VEGETABLE PROTEIN;

ACTIVE TRANSPORT; ARABIDOPSIS; ARTICLE; BIOTECHNOLOGY; BRACHYPODIUM; CHEMICAL STRUCTURE; FLOWER; GENE EXPRESSION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHENOTYPE; PROTEIN MULTIMERIZATION; PROTOPLAST; TRANSGENIC PLANT; TWO HYBRID SYSTEM; ULTRASTRUCTURE;

ACTIVE TRANSPORT, CELL NUCLEUS; AGAMOUS PROTEIN, ARABIDOPSIS; ARABIDOPSIS; ARABIDOPSIS PROTEINS; BIOTECHNOLOGY; BRACHYPODIUM; DNA-BINDING PROTEINS; FLOWERS; GENE EXPRESSION; MADS DOMAIN PROTEINS; MODELS, MOLECULAR; PEPTIDES; PHENOTYPE; PLANT PROTEINS; PLANTS, GENETICALLY MODIFIED; PROTEIN MULTIMERIZATION; PROTOPLASTS; TRANSCRIPTION FACTORS; TWO-HYBRID SYSTEM TECHNIQUES;

ARABIDOPSIS; BRACHYPODIUM; DICOTYLEDONEAE;

EID: 84866735049     PISSN: 09607412     EISSN: 1365313X     Source Type: Journal    
DOI: 10.1111/j.1365-313X.2012.05069.x     Document Type: Article

References (43)

1. Alabadí, D., Oyama, T., Yanovsky, M.J., Harmon, F.G., Más, P., and, Kay, S.A., (2001) Reciprocal regulation between TOC1 and LHY/CCA1 within the Arabidopsis circadian clock. Science, 293, 880-883.
2. Clough, S.J., and, Bent, A.F., (1998) Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. Plant J. 16, 735-743.
3. Green, R.M., and, Tobin, E.M., (1999) Loss of the circadian clock-associated protein 1 in Arabidopsis results in altered clock-regulated gene expression. Proc. Natl Acad. Sci. USA, 96, 4176-4179.
4. Gutierrez, L., Mauriat, M., Guénin, S., et al. (2008) The lack of a systematic validation of reference genes: a serious pitfall undervalued in reverse transcription-polymerase chain reaction (RT-PCR) analysis in plants. Plant Biotechnol. J. 6, 609-618.
5. Hockemeyer, D., Soldner, F., Beard, C., et al. (2009) Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases. Nat. Biotechnol. 27, 851-857.
6. Hockemeyer, D., Wang, H., Kiani, S., et al. (2011) Genetic engineering of human pluripotent cells using TALE nucleases. Nat. Biotechnol. 29, 731-734.
7. Hong, S.Y., Kim, O.K., Kim, S.G., Yang, M.S., and, Park, C.M., (2011) Nuclear import and DNA binding of the ZHD5 transcription factor is modulated by a competitive peptide inhibitor in Arabidopsis. J. Biol. Chem. 286, 1659-1668.
8. Hu, W., and, Ma, H., (2006) Characterization of a novel putative zinc finger gene MIF1: involvement in multiple hormonal regulation of Arabidopsis development. Plant J. 45, 399-422.
9. Hu, W., dePamphilis, C.W., and, Ma, H., (2008) Phylogenetic analysis of the plant-specific zinc finger-homeobox and mini zinc finger gene families. J. Integr. Plant Biol. 50, 1031-1045.
10. Immink, R.G., Gadella, T.W., Ferrario, S. Jr, Busscher, M., and, Angenent, G.C., (2002) Analysis of MADS box protein-protein interactions in living plant cells. Proc. Natl Acad. Sci. USA, 99, 2416-2421.
11. Ito, T., Ng, K.H., Lim, T.S., Yu, H., and, Meyerowitz, E.M., (2007) The homeotic protein AGAMOUS controls late stamen development by regulating a jasmonate biosynthetic gene in Arabidopsis. Plant Cell, 19, 3516-3529.
12. Izawa, T., Foster, R., and, Chua, N.H., (1993) Plant bZIP protein DNA binding specificity. J. Mol. Biol. 230, 1131-1144.
13. Jung, J.H., Yun, J., Seo, P.J., Lee, J.H., and, Park, C.M., (2012) The SOC1-SPL module integrates photoperiod and gibberellic acid signals to control flowering time in Arabidopsis. Plant J. 69, 577-588.
14. Kaufmann, K., Melzer, R., and, Theissen, G., (2005) MIKC-type MADS-domain proteins: structural modularity, protein interactions and network evolution in land plants. Gene, 347, 183-198.
15. Kim, Y.S., Kim, S.G., Park, J.E., Park, H.Y., Lim, M.H., Chua, N.H., and, Park, C.M., (2006) A membrane-bound NAC transcription factor regulates cell division in Arabidopsis. Plant Cell, 18, 3132-3144.
16. Kim, Y.S., Kim, S.G., Lee, M., et al. (2008) HD-ZIP III activity is modulated by competitive inhibitors via a feedback loop in Arabidopsis shoot apical meristem development. Plant Cell, 20, 920-933.
17. Komeda, Y., (2004) Genetic regulation of time to flower in Arabidopsis thaliana. Annu. Rev. Plant Biol. 55, 521-535.
18. Lu, S.X., Knowles, S.M., Andronis, C., Ong, M.S., and, Tobin, E.M., (2009) CIRCADIAN CLOCK ASSOCIATED1 and LATE ELONGATED HYPOCOTYL function synergistically in the circadian clock of Arabidopsis. Plant Physiol. 150, 834-843.
19. Magnani, E., and, Hake, S., (2008) KNOX lost the OX: the Arabidopsis KNATM gene defines a novel class of KNOX transcriptional regulators missing the homeodomain. Plant Cell, 20, 875-887.
20. Miura, K., Jin, J.B., Lee, J., Yoo, C.Y., Stirm, V., Miura, T., Ashworth, E.N., Bressan, R.A., Yun, D.J., and, Hasegawa, P.M., (2007) SIZ1-mediated sumoylation of ICE1 controls CBF3/DREB1A expression and freezing tolerance in Arabidopsis. Plant Cell, 19, 1403-1414.
21. Mizoguchi, T., Wheatley, K., Hanzawa, Y., Wright, L., Mizoguchi, M., Song, H.R., Carré, I.A., and, Coupland, G., (2002) LHY and CCA1 are partially redundant genes required to maintain circadian rhythms in Arabidopsis. Dev. Cell, 2, 629-641.
22. Mizukami, Y., and, Ma, H., (1992) Ectopic expression of the floral homeotic gene AGAMOUS in transgenic Arabidopsis plants alters floral organ identity. Cell, 71, 119-131.
23. Mizukami, Y., Huang, H., Tudor, M., Hu, Y., and, Ma, H., (1996) Functional domains of the floral regulator AGAMOUS: characterization of the DNA binding domain and analysis of dominant negative mutations. Plant Cell, 8, 831-845.
24. Moon, J., Suh, S.S., Lee, H., Choi, K.R., Hong, C.B., Paek, N.C., Kim, S.G., and, Lee, I., (2003) The SOC1 MADS-box gene integrates vernalization and gibberellin signals for flowering in Arabidopsis. Plant J. 35, 613-623.
25. Mur, L.A., Allainguillaume, J., Catalán, P., Hasterok, R., Jenkins, G., Lesniewska, K., Thomas, I., and, Vogel, J., (2011) Exploiting the Brachypodium tool box in cereal and grass research. New Phytol. 191, 334-347.
26. Ng, K.H., Yu, H., and, Ito, T., (2009) AGAMOUS controls GIANT KILLER, a multifunctional chromatin modifier in reproductive organ patterning and differentiation. PLoS Biol. 7, e1000251.
27. Ossowski, S., Schwab, R., and, Weigel, D., (2008) Gene silencing in plants using artificial microRNAs and other small RNAs. Plant J. 53, 674-690.
28. Polo, J.M., Dell'Oso, T., Ranuncolo, S.M., Cerchietti, L., Beck, D., Da Silva, G.F., Prive, G.G., Licht, J.D., and, Melnick, A., (2004) Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells. Nat. Med. 10, 1329-1335.
29. Schaffer, R., Ramsay, N., Samach, A., Corden, S., Putterill, J., Carré, I.A., and, Coupland, G., (1998) The late elongated hypocotyl mutation of Arabidopsis disrupts circadian rhythms and the photoperiodic control of flowering. Cell, 93, 1219-1229.
30. Seo, P.J., Hong, S.Y., Kim, S.G., and, Park, C.M., (2011a) Competitive inhibition of transcription factors by small interfering peptides. Trends Plant Sci. 16, 541-549.
31. Seo, P.J., Kim, M.J., Ryu, J.Y., Jeong, E.Y., and, Park, C.M., (2011b) Two splice variants of the IDD14 transcription factor competitively form nonfunctional heterodimers which may regulate starch metabolism. Nat. Commun. 2, 303.
32. Seo, P.J., Park, M.J., Lim, M.H., Kim, S.G., Lee, M., Baldwin, I.T., and, Park, C.M., (2012) A self-regulatory circuit of CIRCADIAN CLOCK-ASSOCIATED 1 underlies the circadian clock regulation of temperature responses in Arabidopsis. Plant Cell (in press), doi:10.1105/tpc.112.098723.
33. Shukla, V.K., Doyon, Y., Miller, J.C., et al. (2009) Precise genome modification in the crop species Zea mays using zinc-finger nucleases. Nature, 459, 437-441.
34. Small, I., (2007) RNAi for revealing and engineering plant gene functions. Curr. Opin. Biotechnol. 18, 148-153.
35. Staudt, A.C., and, Wenkel, S., (2011) Regulation of protein function by 'microProteins'. EMBO Rep. 12, 35-42.
36. Udvardi, M.K., Czechowski, T., and, Scheible, W.R., (2008) Eleven golden rules of quantitative RT-PCR. Plant Cell, 20, 1736-1737.
37. Vinson, C.R., Hai, T., and, Boyd, S.M., (1993) Dimerization specificity of the leucine zipper-containing bZIP motif on DNA binding: prediction and rational design. Genes Dev. 7, 1047-1058.
38. Vogel, J., and, Hill, T., (2008) High-efficiency Agrobacterium-mediated transformation of Brachypodium distachyon inbred line Bd21-3. Plant Cell Rep. 27, 471-478.
39. Wenkel, S., Emery, J., Hou, B.H., Evans, M.M., and, Barton, M.K., (2007) A feedback regulatory module formed by LITTLE ZIPPER and HD-ZIPIII genes. Plant Cell, 19, 3379-3390.
40. Yakir, E., Hilman, D., Kron, I., Hassidim, M., Melamed-Book, N., and, Green, R.M., (2009) Posttranslational regulation of CIRCADIAN CLOCK ASSOCIATED1 in the circadian oscillator of Arabidopsis. Plant Physiol. 150, 844-857.
41. Yang, S.D., Seo, P.J., Yoon, H.K., and, Park, C.M., (2011) The Arabidopsis NAC transcription factor VNI2 integrates abscisic acid signals into leaf senescence via the COR/RD genes. Plant Cell, 23, 2155-2168.
42. Yap, J.L., Chauhan, J., Jung, K.Y., Chen, L., Prochownik, E.V., and, Fletcher, S., (2012) Small-molecule inhibitors of dimeric transcription factors: Antagonism of protein-protein and protein-DNA interactions. Med. Chem. Commun. 3, 541-551.
43. Yoo, S.D., Cho, Y.H., and, Sheen, J., (2007) Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis. Nat. Protoc. 2, 1565-1572.