-
1
-
-
80755125565
-
Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity
-
Anastassiadis T, Deacon SW, Devarajan K, Ma H, Peterson JR (2011) Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity. Nat Biotechnol 29:1039-1045
-
(2011)
Nat Biotechnol
, vol.29
, pp. 1039-1045
-
-
Anastassiadis, T.1
Deacon, S.W.2
Devarajan, K.3
Ma, H.4
Peterson, J.R.5
-
2
-
-
0019786390
-
Rapid and reversible reduction of junctional permeability in cells infected with a temperature-sensitive mutant of avian sarcoma virus
-
Atkinson MM, Menko SS, Johnson RG, Sheppard JR, Sheridan JD (1981) Rapid and reversible reduction of junctional permeability in cells infected with a temperature-sensitive mutant of avian sarcoma virus. J Cell Biol 91:573-578
-
(1981)
J Cell Biol
, vol.91
, pp. 573-578
-
-
Atkinson, M.M.1
Menko, S.S.2
Johnson, R.G.3
Sheppard, J.R.4
Sheridan, J.D.5
-
3
-
-
19944433628
-
Identification and characterization of pleckstrin-homology-domain- dependent and isoenzyme-specific akt inhibitors
-
Barrett SF, Defeo-Jones D, Fu S, Hancock PJ, Haskell KM, Jones RE, Kahana JA, Kral AM, Leander K, Lee LL, Malinowski J, McAvoy EM, Nahas DD, Robinson RG, Huber HE (2005) Identification and characterization of pleckstrin-homology- domain-dependent and isoenzyme-specific Akt inhibitors. Bio-chem J 385:399-408
-
(2005)
Bio-chem J
, vol.385
, pp. 399-408
-
-
Barrett, S.F.1
Defeo-Jones, D.2
Fu, S.3
Hancock, P.J.4
Haskell, K.M.5
Jones, R.E.6
Kahana, J.A.7
Kral, A.M.8
Leander, K.9
Lee, L.L.10
Malinowski, J.11
McAvoy, E.M.12
Nahas, D.D.13
Robinson, R.G.14
Huber, H.E.15
-
4
-
-
0027722257
-
On the mechanisms of cell uncoupling induced by a tumor promoter phorbol ester in clone 9 cells, a rat liver epithelial cell line
-
Berthoud VM, Rook MB, Traub O, Hertzberg EL, Saez JC (1993) On the mechanisms of cell uncoupling induced by a tumor promoter phorbol ester in clone 9 cells, a rat liver epithelial cell line. Eur J Cell Biol 62:384-396
-
(1993)
Eur J Cell Biol
, vol.62
, pp. 384-396
-
-
Berthoud, V.M.1
Rook, M.B.2
Traub, O.3
Hertzberg, E.L.4
Saez, J.C.5
-
5
-
-
58149104029
-
Gap junctions and cancer: New functions for an old story
-
Cronier L, Crespin S, Strale PO, Defamie N, Mesnil M (2009) Gap junctions and cancer: new functions for an old story. Antioxid Redox Signal 11:323-338
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 323-338
-
-
Cronier, L.1
Crespin, S.2
Strale, P.O.3
Defamie, N.4
Mesnil, M.5
-
6
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies SP, Reddy H, Caivano M, Cohen P (2000) Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 351:95-105
-
(2000)
Biochem J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
7
-
-
0035757714
-
Protein kinase C-epsilon mediates phorbol ester-induced phos-phorylation of connexin-43
-
Doble BW, Ping P, Fandrich RR, Cattini PA, Kardami E (2001) Protein kinase C-epsilon mediates phorbol ester-induced phos-phorylation of connexin-43. Cell Commun Adhes 8:253-256
-
(2001)
Cell Commun Adhes
, vol.8
, pp. 253-256
-
-
Doble, B.W.1
Ping, P.2
Fandrich, R.R.3
Cattini, P.A.4
Kardami, E.5
-
8
-
-
0029781699
-
PH regulation of connexin43: Molecular analysis of the gating particle
-
Ek-Vitorin JF, Calero G, Morley GE, Coombs W, Taffet SM, Delmar M (1996) PH regulation of connexin43: molecular analysis of the gating particle. Biophys J 71:1273-1284
-
(1996)
Biophys J
, vol.71
, pp. 1273-1284
-
-
Ek-Vitorin, J.F.1
Calero, G.2
Morley, G.E.3
Coombs, W.4
Taffet, S.M.5
Delmar, M.6
-
9
-
-
0033214147
-
Xenopus oocyte maturation: New lessons from a good egg
-
Ferrell JE Jr (1999) Xenopus oocyte maturation: new lessons from a good egg. BioEssays 21:833-842
-
(1999)
BioEssays
, vol.21
, pp. 833-842
-
-
Ferrell Jr., J.E.1
-
10
-
-
13144252170
-
The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein
-
Giepmans BN, Moolenaar WH (1998) The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein. Curr Biol 8:931-934
-
(1998)
Curr Biol
, vol.8
, pp. 931-934
-
-
Giepmans, B.N.1
Moolenaar, W.H.2
-
11
-
-
0035806979
-
Gap junction protein connexin-43 interacts directly with microtubules
-
Giepmans BN, Verlaan I, Hengeveld T, Janssen H, Calafat J, Falk MM, Moolenaar WH (2001) Gap junction protein connexin-43 interacts directly with microtubules. Curr Biol 11:1364-1368
-
(2001)
Curr Biol
, vol.11
, pp. 1364-1368
-
-
Giepmans, B.N.1
Verlaan, I.2
Hengeveld, T.3
Janssen, H.4
Calafat, J.5
Falk, M.M.6
Moolenaar, W.H.7
-
12
-
-
0031821086
-
Direct isolation and analysis of endogenous trans-junctional ADP from cx43 transfected C6 glioma cells
-
Goldberg GS, Lampe PD, Sheedy D, Stewart CC, Nicholson BJ, Naus CC (1998) Direct isolation and analysis of endogenous trans-junctional ADP from Cx43 transfected C6 glioma cells. Exp Cell Res 239:82-92
-
(1998)
Exp Cell Res
, vol.239
, pp. 82-92
-
-
Goldberg, G.S.1
Lampe, P.D.2
Sheedy, D.3
Stewart, C.C.4
Nicholson, B.J.5
Naus, C.C.6
-
13
-
-
0032514173
-
A particle-receptor model for the insulin-induced closure of connexin43 channels
-
Homma N, Alvarado JL, Coombs W, Stergiopoulos K, Taffet SM, Lau AF, Delmar M (1998) A particle-receptor model for the insulin-induced closure of connexin43 channels. Circ Res 83:27-32
-
(1998)
Circ Res
, vol.83
, pp. 27-32
-
-
Homma, N.1
Alvarado, J.L.2
Coombs, W.3
Stergiopoulos, K.4
Taffet, S.M.5
Lau, A.F.6
Delmar, M.7
-
14
-
-
0025224223
-
Biophysical and molecular mechanisms of shaker potassium channel inactivation
-
Hoshi T, Zagotta WN, Aldrich RW (1990) Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science 250:533-538
-
(1990)
Science
, vol.250
, pp. 533-538
-
-
Hoshi, T.1
Zagotta, W.N.2
Aldrich, R.W.3
-
15
-
-
0031824861
-
Platelet-derived growth factor-induced disruption of gap junctional communication and phosphorylation of connexin43 involves protein kinase C and mitogen-activated protein kinase
-
Hossain MZ, Ao P, Boynton AL (1998) Platelet-derived growth factor-induced disruption of gap junctional communication and phosphorylation of connexin43 involves protein kinase C and mitogen-activated protein kinase. J Cell Physiol 176:332-341
-
(1998)
J Cell Physiol
, vol.176
, pp. 332-341
-
-
Hossain, M.Z.1
Ao, P.2
Boynton, A.L.3
-
16
-
-
0032978738
-
Mitogen-activated protein kinase and phosphorylation of connexin43 are not sufficient for the disruption of gap junctional communication by platelet-derived growth factor and tetradecanoylphorbol acetate
-
Hossain MZ, Jagdale AB, Ao P, Boynton AL (1999a) Mitogen-activated protein kinase and phosphorylation of connexin43 are not sufficient for the disruption of gap junctional communication by platelet-derived growth factor and tetradecanoylphorbol acetate. J Cell Physiol 179:87-96
-
(1999)
J Cell Physiol
, vol.179
, pp. 87-96
-
-
Hossain, M.Z.1
Jagdale, A.B.2
Ao, P.3
Boynton, A.L.4
-
17
-
-
0033537929
-
Disruption of gap junctional communication by the platelet-derived growth factor is mediated via multiple signaling pathways
-
Hossain MZ, Jagdale AB, Ao P, Kazlauskas A, Boynton AL (1999b) Disruption of gap junctional communication by the platelet-derived growth factor is mediated via multiple signaling pathways. J Biol Chem 274:10489-10496
-
(1999)
J Biol Chem
, vol.274
, pp. 10489-10496
-
-
Hossain, M.Z.1
Jagdale, A.B.2
Ao, P.3
Kazlauskas, A.4
Boynton, A.L.5
-
18
-
-
33646130857
-
V-src requires ras signaling for the suppression of gap junctional intercellular communication
-
Ito S, Ito Y, Senga T, Hattori S, Matsuo S, Hamaguchi M (2006) v-Src requires Ras signaling for the suppression of gap junctional intercellular communication. Oncogene 25:2420-2424
-
(2006)
Oncogene
, vol.25
, pp. 2420-2424
-
-
Ito, S.1
Ito, Y.2
Senga, T.3
Hattori, S.4
Matsuo, S.5
Hamaguchi, M.6
-
19
-
-
77956781405
-
PI3K/Akt signaling is involved in the disruption of gap junctional communication caused by v-Src and TNF-a
-
Ito S, Hyodo T, Hasegawa H, Yuan H, Hamaguchi M, Senga T (2010) PI3K/Akt signaling is involved in the disruption of gap junctional communication caused by v-Src and TNF-a. Biochem Biophys Res Commun 400:230-235
-
(2010)
Biochem Biophys Res Commun
, vol.400
, pp. 230-235
-
-
Ito, S.1
Hyodo, T.2
Hasegawa, H.3
Yuan, H.4
Hamaguchi, M.5
Senga, T.6
-
20
-
-
0027320055
-
Epidermal growth factor stimulates the disruption of gap junctional communication and connexin43 phosphorylation independent of 12-O- tetradecanoylphorbol 13-acetate-sensitive protein kinase C: The possible involvement of mitogen-activated protein kinase
-
Kanemitsu MY, Lau AF (1993) Epidermal growth factor stimulates the disruption of gap junctional communication and connexin43 phosphorylation independent of 12-O-tetradecanoylphorbol 13-acetate-sensitive protein kinase C: the possible involvement of mitogen-activated protein kinase. Mol Biol Cell 4:837-848
-
(1993)
Mol Biol Cell
, vol.4
, pp. 837-848
-
-
Kanemitsu, M.Y.1
Lau, A.F.2
-
21
-
-
0031974956
-
Cdc2-mediated phos-phorylation of the gap junction protein, connexin43, during mitosis
-
Kanemitsu MY, Jiang W, Eckhart W (1998) Cdc2-mediated phos-phorylation of the gap junction protein, connexin43, during mitosis. Cell Growth Differ 9:13-21
-
(1998)
Cell Growth Differ
, vol.9
, pp. 13-21
-
-
Kanemitsu, M.Y.1
Jiang, W.2
Eckhart, W.3
-
22
-
-
0034667593
-
Meaningful relationships: The regulation of the ras/raf/MEK/ERK pathway by protein interactions
-
Kolch W (2000) Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. Biochem J 351(Pt 2):289-305
-
(2000)
Biochem J
, vol.351
, Issue.PART 2
, pp. 289-305
-
-
Kolch, W.1
-
23
-
-
0030028301
-
The gap junction communication channel
-
Kumar NM, Gilula NB (1996) The gap junction communication channel. Cell 84:381-388
-
(1996)
Cell
, vol.84
, pp. 381-388
-
-
Kumar, N.M.1
Gilula, N.B.2
-
24
-
-
1942470517
-
The effects of connexin phosphorylation on gap junctional communication
-
Lampe PD, Lau AF (2004) The effects of connexin phosphorylation on gap junctional communication. Int J Biochem Cell Biol 36: 1171-1186
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 1171-1186
-
-
Lampe, P.D.1
Lau, A.F.2
-
25
-
-
0034717680
-
Phosphorylation of connexin43 on serine368 by protein kinase C regulates gap junctional communication
-
Lampe PD, TenBroek EM, Burt JM, Kurata WE, Johnson RG, Lau AF (2000) Phosphorylation of connexin43 on serine368 by protein kinase C regulates gap junctional communication. J Cell Biol 149:1503-1512
-
(2000)
J Cell Biol
, vol.149
, pp. 1503-1512
-
-
Lampe, P.D.1
TenBroek, E.M.2
Burt, J.M.3
Kurata, W.E.4
Johnson, R.G.5
Lau, A.F.6
-
26
-
-
0028829346
-
Negative feedback regulation and desensitization of insulin-and epidermal growth factor-stimulated p21ras activation
-
Langlois WJ, Sasaoka T, Saltiel AR, Olefsky JM (1995) Negative feedback regulation and desensitization of insulin-and epidermal growth factor-stimulated p21ras activation. J Biol Chem 270:25320-25323
-
(1995)
J Biol Chem
, vol.270
, pp. 25320-25323
-
-
Langlois, W.J.1
Sasaoka, T.2
Saltiel, A.R.3
Olefsky, J.M.4
-
27
-
-
0027067884
-
Epidermal growth factor disrupts gap-junctional communication and induces phosphorylation of connexin43 on serine
-
Lau AF, Kanemitsu MY, Kurata WE, Danesh S, Boynton AL (1992) Epidermal growth factor disrupts gap-junctional communication and induces phosphorylation of connexin43 on serine. Mol Biol Cell 3:865-874
-
(1992)
Mol Biol Cell
, vol.3
, pp. 865-874
-
-
Lau, A.F.1
Kanemitsu, M.Y.2
Kurata, W.E.3
Danesh, S.4
Boynton, A.L.5
-
28
-
-
0035921428
-
V-src phosphorylation of connexin 43 on tyr247 and tyr265 disrupts gap junctional communication
-
Lin R, Warn-Cramer BJ, Kurata WE, Lau AF (2001) v-Src phosphorylation of connexin 43 on Tyr247 and Tyr265 disrupts gap junctional communication. J Cell Biol 154:815-827
-
(2001)
J Cell Biol
, vol.154
, pp. 815-827
-
-
Lin, R.1
Warn-Cramer, B.J.2
Kurata, W.E.3
Lau, A.F.4
-
29
-
-
0025604168
-
Cell-to-cell communication and the control of growth
-
Loewenstein WR (1990) Cell-to-cell communication and the control of growth. Am Rev Respir Dis 142:S48-S53
-
(1990)
Am Rev Respir Dis
, vol.142
-
-
Loewenstein, W.R.1
-
30
-
-
0037163050
-
Regulation of raf-akt cross-talk
-
Moelling K, Schad K, Bosse M, Zimmermann S, Schweneker M (2002) Regulation of Raf-Akt cross-talk. J Biol Chem 277:31099-31106
-
(2002)
J Biol Chem
, vol.277
, pp. 31099-31106
-
-
Moelling, K.1
Schad, K.2
Bosse, M.3
Zimmermann, S.4
Schweneker, M.5
-
31
-
-
0028283183
-
Human connexin43 gap junction channels. Regulation of unitary conductances by phosphorylation
-
Moreno AP, Saez JC, Fishman GI, Spray DC (1994) Human connexin43 gap junction channels. Regulation of unitary conductances by phosphorylation. Circ Res 74:1050-1057
-
(1994)
Circ Res
, vol.74
, pp. 1050-1057
-
-
Moreno, A.P.1
Saez, J.C.2
Fishman, G.I.3
Spray, D.C.4
-
32
-
-
0030050142
-
Intramolecular interactions mediate pH regulation of connexin43 channels
-
Morley GE, Taffet SM, Delmar M (1996) Intramolecular interactions mediate pH regulation of connexin43 channels. Biophys J 70:1294-1302
-
(1996)
Biophys J
, vol.70
, pp. 1294-1302
-
-
Morley, G.E.1
Taffet, S.M.2
Delmar, M.3
-
33
-
-
0025155347
-
Differential phosphorylation of the gap junction protein conn-exin43 in junctional communication-competent and -deficient cell lines
-
Musil LS, Cunningham BA, Edelman GM, Goodenough DA (1990) Differential phosphorylation of the gap junction protein conn-exin43 in junctional communication-competent and -deficient cell lines. J Cell Biol 111:2077-2088
-
(1990)
J Cell Biol
, vol.111
, pp. 2077-2088
-
-
Musil, L.S.1
Cunningham, B.A.2
Edelman, G.M.3
Goodenough, D.A.4
-
34
-
-
37849037721
-
Akt phosphorylates connexin43 on ser373, a "mode-1," binding site for 14-3-3
-
Park DJ, Wallick CJ, Martyn KD, Lau AF, Jin C, Warn-Cramer BJ (2007) Akt phosphorylates connexin43 on Ser373, a "mode-1" binding site for 14-3-3. Cell Commun Adhes 14:211-226
-
(2007)
Cell Commun Adhes
, vol.14
, pp. 211-226
-
-
Park, D.J.1
Wallick, C.J.2
Martyn, K.D.3
Lau, A.F.4
Jin, C.5
Warn-Cramer, B.J.6
-
35
-
-
0032978365
-
Transformation by v-src: Ras-MAPK and PI3K-mTOR mediate parallel pathways
-
Penuel E, Martin GS (1999) Transformation by v-Src: Ras-MAPK and PI3K-mTOR mediate parallel pathways. Mol Biol Cell 10:1693-1703
-
(1999)
Mol Biol Cell
, vol.10
, pp. 1693-1703
-
-
Penuel, E.1
Martin, G.S.2
-
36
-
-
0039791449
-
Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes
-
Schonwasser DC, Marais RM, Marshall CJ, Parker PJ (1998) Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes. Mol Cell Biol 18:790-798
-
(1998)
Mol Cell Biol
, vol.18
, pp. 790-798
-
-
Schonwasser, D.C.1
Marais, R.M.2
Marshall, C.J.3
Parker, P.J.4
-
37
-
-
34547111072
-
SRC utilizes cas to block gap junctional communication mediated by connexin43
-
Shen Y, Khusial PR, Li X, Ichikawa H, Moreno AP, Goldberg GS (2007) SRC utilizes Cas to block gap junctional communication mediated by connexin43. J Biol Chem 282:18914-18921
-
(2007)
J Biol Chem
, vol.282
, pp. 18914-18921
-
-
Shen, Y.1
Khusial, P.R.2
Li, X.3
Ichikawa, H.4
Moreno, A.P.5
Goldberg, G.S.6
-
38
-
-
48449089173
-
Connexin 43 in LA-25 cells with active v-src is phosphorylated on Y247, Y265, S262, S279/282, and S368 via multiple signaling pathways
-
Solan JL, Lampe PD (2008) Connexin 43 in LA-25 cells with active v-src is phosphorylated on Y247, Y265, S262, S279/282, and S368 via multiple signaling pathways. Cell Commun Adhes 15:75-84
-
(2008)
Cell Commun Adhes
, vol.15
, pp. 75-84
-
-
Solan, J.L.1
Lampe, P.D.2
-
39
-
-
11144230049
-
Structural changes in the carboxyl terminus of the gap junction protein connexin43 indicates signaling between binding domains for c-src and zonula occludens-1
-
Sorgen PL, Duffy HS, Sahoo P, Coombs W, Delmar M, Spray DC (2004) Structural changes in the carboxyl terminus of the gap junction protein connexin43 indicates signaling between binding domains for c-Src and zonula occludens-1. J Biol Chem 279: 54695-54701
-
(2004)
J Biol Chem
, vol.279
, pp. 54695-54701
-
-
Sorgen, P.L.1
Duffy, H.S.2
Sahoo, P.3
Coombs, W.4
Delmar, M.5
Spray, D.C.6
-
40
-
-
27244462402
-
Tyrosine phosphorylation of the gap junction protein connexin43 is required for the pp 60v-src-induced inhibition of communication
-
Swenson KI, Piwnica-Worms H, McNamee H, Paul DL (1990) Tyrosine phosphorylation of the gap junction protein connexin43 is required for the pp 60v-src-induced inhibition of communication. Cell Regul 1:989-1002
-
(1990)
Cell Regul
, vol.1
, pp. 989-1002
-
-
Swenson, K.I.1
Piwnica-Worms, H.2
McNamee, H.3
Paul, D.L.4
-
41
-
-
0032557460
-
Direct association of the gap junction protein connexin-43 with ZO-1 in cardiac myocytes
-
Toyofuku T, Yabuki M, Otsu K, Kuzuya T, Hori M, Tada M (1998) Direct association of the gap junction protein connexin-43 with ZO-1 in cardiac myocytes. J Biol Chem 273:12725-12731
-
(1998)
J Biol Chem
, vol.273
, pp. 12725-12731
-
-
Toyofuku, T.1
Yabuki, M.2
Otsu, K.3
Kuzuya, T.4
Hori, M.5
Tada, M.6
-
42
-
-
0035910415
-
C-src regulates the interaction between connexin-43 and ZO-1 in cardiac myocytes
-
Toyofuku T, Akamatsu Y, Zhang H, Kuzuya T, Tada M, Hori M (2001) c-Src regulates the interaction between connexin-43 and ZO-1 in cardiac myocytes. J Biol Chem 276:1780-1788
-
(2001)
J Biol Chem
, vol.276
, pp. 1780-1788
-
-
Toyofuku, T.1
Akamatsu, Y.2
Zhang, H.3
Kuzuya, T.4
Tada, M.5
Hori, M.6
-
43
-
-
0030022421
-
Characterization of the mitogen-activated protein kinase phosphorylation sites on the connexin-43 gap junction protein
-
Warn-Cramer BJ, Lampe PD, Kurata WE, Kanemitsu MY, Loo LW, Eckhart W et al (1996) Characterization of the mitogen-activated protein kinase phosphorylation sites on the connexin-43 gap junction protein. J Biol Chem 271:3779-3786
-
(1996)
J Biol Chem
, vol.271
, pp. 3779-3786
-
-
Warn-Cramer, B.J.1
Lampe, P.D.2
Kurata, W.E.3
Kanemitsu, M.Y.4
Loo, L.W.5
Eckhart, W.6
-
44
-
-
0028822259
-
Selective activation of protein kinase C isoforms by v-src
-
Zang Q, Frankel P, Foster DA (1995) Selective activation of protein kinase C isoforms by v-Src. Cell Growth Differ 6:1367-1373
-
(1995)
Cell Growth Differ
, vol.6
, pp. 1367-1373
-
-
Zang, Q.1
Frankel, P.2
Foster, D.A.3
-
45
-
-
0033535338
-
Dissection of the molecular basis of pp 60v-src induced gating of connexin 43 gap junction channels
-
Zhou L, Kasperek EM, Nicholson BJ (1999) Dissection of the molecular basis of pp 60v-src induced gating of connexin 43 gap junction channels. J Cell Biol 144:1033-1045
-
(1999)
J Cell Biol
, vol.144
, pp. 1033-1045
-
-
Zhou, L.1
Kasperek, E.M.2
Nicholson, B.J.3
|