Antiangiogenic treatments and mechanisms of action in renal cell carcinoma

Investigational New Drugs

Volumn 30, Issue 4, 2012, Pages 1791-1801

  Négrier, Sylvie ^a   Raymond, Eric ^b  

^a UNIVERSITÉ DE LYON   (France)

^b BEAUJON HOSPITAL   (France)

Author keywords

Angiogenesis; Mode of action; Renal cell carcinoma; Targeted therapy; Tolerability

Indexed keywords

ALPHA INTERFERON; ANGIOGENESIS INHIBITOR; AXITINIB; BEVACIZUMAB; CD135 ANTIGEN; CEDIRANIB; COLONY STIMULATING FACTOR 1; EVEROLIMUS; FIBROBLAST GROWTH FACTOR RECEPTOR 2; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN; PAZOPANIB; PLACEBO; PLATELET DERIVED GROWTH FACTOR RECEPTOR; SORAFENIB; STEM CELL FACTOR RECEPTOR; SUNITINIB; TEMSIROLIMUS; TIVOZANIB; VASCULOTROPIN RECEPTOR;

ACNE; ANEMIA; ANTIANGIOGENIC ACTIVITY; ANTIANGIOGENIC THERAPY; ANTINEOPLASTIC ACTIVITY; ASTHENIA; BLEEDING DISORDER; CANCER INHIBITION; CANCER PROGNOSIS; CARCINOGENESIS; CARDIOTOXICITY; DIARRHEA; DRUG EFFICACY; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG TARGETING; DRUG TOLERABILITY; EPISTAXIS; FATIGUE; HAND FOOT SYNDROME; HUMAN; HYPERTENSION; HYPOTHYROIDISM; KIDNEY METASTASIS; LEUKOPENIA; MACULOPAPULAR RASH; MUCOSA INFLAMMATION; NEUTROPENIA; NONHUMAN; OVERALL SURVIVAL; PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PNEUMONIA; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; PROTEINURIA; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SIDE EFFECT; SIGNAL TRANSDUCTION; SKIN TOXICITY; THROMBOCYTOPENIA;

ANGIOGENESIS INHIBITORS; CARCINOMA, RENAL CELL; HUMANS; KIDNEY NEOPLASMS; MODELS, BIOLOGICAL; NEOPLASM METASTASIS; PHYSICIAN'S PRACTICE PATTERNS;

EID: 84866731284     PISSN: 01676997     EISSN: 15730646     Source Type: Journal    
DOI: 10.1007/s10637-011-9677-6     Document Type: Review

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