메뉴 건너뛰기




Volumn 20, Issue 8, 2003, Pages 757-766

SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model

Author keywords

435 HAL Luc; Bioluminescence imaging; Breast cancer; CSF 1R; Metastasis; Osteoclast

Indexed keywords

COLONY STIMULATING FACTOR 1; COLONY STIMULATING FACTOR RECEPTOR; OSTEOCLAST DIFFERENTIATION FACTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE INHIBITOR; PYRIDINOLINE; SUNITINIB;

EID: 9144274970     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:CLIN.0000006873.65590.68     Document Type: Article
Times cited : (304)

References (38)
  • 1
    • 0023137823 scopus 로고
    • The clinical course of bone metastases from breast cancer
    • Coleman RE, Rubens RD. The clinical course of bone metastases from breast cancer. Br J Cancer 1987; 55: 61-6.
    • (1987) Br J Cancer , vol.55 , pp. 61-66
    • Coleman, R.E.1    Rubens, R.D.2
  • 2
    • 0032824734 scopus 로고    scopus 로고
    • Current management of metastatic breast cancer
    • Perez EA. Current management of metastatic breast cancer. Semin Oncol 1999; 26: (4 Suppl 12): 1-10.
    • (1999) Semin Oncol , vol.26 , Issue.4 SUPPL. 12 , pp. 1-10
    • Perez, E.A.1
  • 3
    • 0033996120 scopus 로고    scopus 로고
    • Review of cellular mechanisms of tumor osteolysis
    • Clohisy DR, Perkins SL, Ramnaraine ML. Review of cellular mechanisms of tumor osteolysis. Clin Orthop 2000; 373: 104-14.
    • (2000) Clin Orthop , vol.373 , pp. 104-114
    • Clohisy, D.R.1    Perkins, S.L.2    Ramnaraine, M.L.3
  • 4
    • 0025977548 scopus 로고
    • Congenital osteoclast deficiency in osteopetrotic (op/op) mice is cured by injections of macrophage colony-stimulating factor
    • Kodama H, Yamasaki A, Nose M et al. Congenital osteoclast deficiency in osteopetrotic (op/op) mice is cured by injections of macrophage colony-stimulating factor. J Exp Med 1991; 173: 269-72.
    • (1991) J Exp Med , vol.173 , pp. 269-272
    • Kodama, H.1    Yamasaki, A.2    Nose, M.3
  • 5
    • 0036892127 scopus 로고    scopus 로고
    • Tyrosines 559 and 807 in the cytoplasmic tail of the macrophage colony-stimulating factor receptor play distinct roles in osteoclast differentiation and function
    • Feng X, Takeshita S, Namba N et al. Tyrosines 559 and 807 in the cytoplasmic tail of the macrophage colony-stimulating factor receptor play distinct roles in osteoclast differentiation and function. Endocrinology 2002; 143: 4868-74.
    • (2002) Endocrinology , vol.143 , pp. 4868-4874
    • Feng, X.1    Takeshita, S.2    Namba, N.3
  • 6
    • 0030734791 scopus 로고    scopus 로고
    • Colony-stimulating factor-1 induces cytoskeletal reorganization and c-src-dependent tyrosine phosphorylation of selected cellular proteins in rodent osteoclasts
    • Insogna KL, Sahni M, Grey AB et al. Colony-stimulating factor-1 induces cytoskeletal reorganization and c-src-dependent tyrosine phosphorylation of selected cellular proteins in rodent osteoclasts. J Clin Invest 1997; 100: 2476-85.
    • (1997) J Clin Invest , vol.100 , pp. 2476-2485
    • Insogna, K.L.1    Sahni, M.2    Grey, A.B.3
  • 7
    • 12244301581 scopus 로고    scopus 로고
    • In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of pharmacokinetic/pharmacodynamic relationship
    • Mendel DB, Laird AD, Xin X et al. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res 2003; 9: 327-37.
    • (2003) Clin Cancer Res , vol.9 , pp. 327-337
    • Mendel, D.B.1    Laird, A.D.2    Xin, X.3
  • 8
    • 0038204144 scopus 로고    scopus 로고
    • SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
    • O'Farrell AM, Abrams TJ, Yuen HA et al. SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood 2003; 101: 3597-605.
    • (2003) Blood , vol.101 , pp. 3597-3605
    • O'Farrell, A.M.1    Abrams, T.J.2    Yuen, H.A.3
  • 9
    • 78650874372 scopus 로고    scopus 로고
    • SU11248 inhibits kit and PDGFR beta in preclinical models of human small cell lung cancer
    • Abrams T, Lee LB, Murray LJ et al. SU11248 inhibits kit and PDGFR beta in preclinical models of human small cell lung cancer. Mol Therapeutics 2003; 2: 471-8.
    • (2003) Mol Therapeutics , vol.2 , pp. 471-478
    • Abrams, T.1    Lee, L.B.2    Murray, L.J.3
  • 10
    • 0037232108 scopus 로고    scopus 로고
    • Small molecule tyrosine kinase inhibitors: Clinical development of anticancer agents
    • Laird AD, Cherrington JM. Small molecule tyrosine kinase inhibitors: Clinical development of anticancer agents. Expert Opin Invest Drugs 2003; 12: 51-64.
    • (2003) Expert Opin Invest Drugs , vol.12 , pp. 51-64
    • Laird, A.D.1    Cherrington, J.M.2
  • 11
    • 0033510649 scopus 로고    scopus 로고
    • Characterization of spontaneous metastasis in an aggressive breast carcinoma model using flow cytometry
    • Schmidt CM, Settle SL, Keene JL et al. Characterization of spontaneous metastasis in an aggressive breast carcinoma model using flow cytometry. Clin Exp Metastasis 1999; 17: 537-44.
    • (1999) Clin Exp Metastasis , vol.17 , pp. 537-544
    • Schmidt, C.M.1    Settle, S.L.2    Keene, J.L.3
  • 12
    • 0012944342 scopus 로고    scopus 로고
    • MDA-MB-435 human breast carcinoma metastasis to bone
    • Harms JF, Welch DR. MDA-MB-435 human breast carcinoma metastasis to bone. Clin Exp Metastasis 2003; 20: 327-34.
    • (2003) Clin Exp Metastasis , vol.20 , pp. 327-334
    • Harms, J.F.1    Welch, D.R.2
  • 13
    • 0034005650 scopus 로고    scopus 로고
    • Use of reporter genes for optical measurements of neoplastic disease in vivo
    • Contag CH, Jenkins D and Contag PR et al. Use of reporter genes for optical measurements of neoplastic disease in vivo. Neoplasia 2000; 2: 41-52.
    • (2000) Neoplasia , vol.2 , pp. 41-52
    • Contag, C.H.1    Jenkins, D.2    Contag, P.R.3
  • 14
    • 0036118348 scopus 로고    scopus 로고
    • Optical imaging of Cancer Metastasis to Bone Marrow: A mouse model of minimal residual disease
    • Wetterwald A, van der Pluijm G, Que et al. Optical imaging of Cancer Metastasis to Bone Marrow: A mouse model of minimal residual disease. Am J Pathol 2002; 160: 1143-53.
    • (2002) Am J Pathol , vol.160 , pp. 1143-1153
    • Wetterwald, A.1    Van Der Pluijm, G.2    Que3
  • 15
    • 0013312329 scopus 로고    scopus 로고
    • Inhibition of FLT3 in MLL: Validation of a therapeutic target identified by gene expression based classification
    • Armstrong SA, Kung AL, Mabon ME et al. Inhibition of FLT3 in MLL: Validation of a therapeutic target identified by gene expression based classification. Cancer Cell 2003; 3: 173-83.
    • (2003) Cancer Cell , vol.3 , pp. 173-183
    • Armstrong, S.A.1    Kung, A.L.2    Mabon, M.E.3
  • 16
    • 0024262906 scopus 로고
    • A murine model of experimental metastasis to bone and bone marrow
    • Arguello F, Baggs RB, Frantz CN. A murine model of experimental metastasis to bone and bone marrow. Cancer Res 1988; 48: 6876-81.
    • (1988) Cancer Res , vol.48 , pp. 6876-6881
    • Arguello, F.1    Baggs, R.B.2    Frantz, C.N.3
  • 17
    • 0029905557 scopus 로고    scopus 로고
    • Standardization of pyridinium crosslinks, pyridinoline and deoxypyridinoline, for use as biochemical markers of collagen degradation
    • Robins SP, Duncan A, Wilson N et al. Standardization of pyridinium crosslinks, pyridinoline and deoxypyridinoline, for use as biochemical markers of collagen degradation. Clin Chem 1996; 42: 1621-6.
    • (1996) Clin Chem , vol.42 , pp. 1621-1626
    • Robins, S.P.1    Duncan, A.2    Wilson, N.3
  • 18
    • 0036846281 scopus 로고    scopus 로고
    • Receptor activator for nuclear factor kappaB ligand and osteoprotegerin:regulators of bone physiology and immune responses/potential therapeutic agents and biochemical markers
    • Buckley KA, Fraser WD. Receptor activator for nuclear factor kappaB ligand and osteoprotegerin:regulators of bone physiology and immune responses/potential therapeutic agents and biochemical markers. Ann Clin Biochem 2002; 39: 551-6.
    • (2002) Ann Clin Biochem , vol.39 , pp. 551-556
    • Buckley, K.A.1    Fraser, W.D.2
  • 19
    • 0025038279 scopus 로고
    • Evidence that the action of calcitonin on rat osteoclasts is mediated by two G proteins acting via separate post-receptor pathways
    • Zaidi M, Datta HK, Moonga BS et al. Evidence that the action of calcitonin on rat osteoclasts is mediated by two G proteins acting via separate post-receptor pathways. J Endocrinol 1990; 126: 473-81.
    • (1990) J Endocrinol , vol.126 , pp. 473-481
    • Zaidi, M.1    Datta, H.K.2    Moonga, B.S.3
  • 20
    • 0035816314 scopus 로고    scopus 로고
    • Cellular mechanisms of bone resorption in breast carcinoma
    • Hunt NC, Fujikawa Y, Sabokbar A et al. Cellular mechanisms of bone resorption in breast carcinoma. Br J Cancer 2001; 85: 78-84
    • (2001) Br J Cancer , vol.85 , pp. 78-84
    • Hunt, N.C.1    Fujikawa, Y.2    Sabokbar, A.3
  • 21
    • 0038338828 scopus 로고    scopus 로고
    • The relationship between urinary pyridinoline, deoxypyridinoline and bone metastasis in a rat breast cancer model
    • Tamura H, Ishii S, Ikeda T et al. The relationship between urinary pyridinoline, deoxypyridinoline and bone metastasis in a rat breast cancer model. Breast Cancer 1999; 6: 23-8.
    • (1999) Breast Cancer , vol.6 , pp. 23-28
    • Tamura, H.1    Ishii, S.2    Ikeda, T.3
  • 22
    • 0037036949 scopus 로고    scopus 로고
    • New drugs for breast cancer
    • Smith IE. New drugs for breast cancer. Lancet 2002; 360: 790-2.
    • (2002) Lancet , vol.360 , pp. 790-792
    • Smith, I.E.1
  • 23
    • 0034861109 scopus 로고    scopus 로고
    • Breast cancer increases osteoclastogenesis by secreting M-CSF and upregulating RANKL in stromal cells
    • Mancino AT, Klimberg VS, Yamamoto M et al. Breast cancer increases osteoclastogenesis by secreting M-CSF and upregulating RANKL in stromal cells. J Surg Res 2001; 100: 18-24.
    • (2001) J Surg Res , vol.100 , pp. 18-24
    • Mancino, A.T.1    Klimberg, V.S.2    Yamamoto, M.3
  • 24
    • 0036192497 scopus 로고    scopus 로고
    • Hormonal regulation of the c-fms proto-oncogene in breast cancer cells is mediated by a composite glucocorticoid response element
    • Flick MM, Sapi E, Kacinski BM, Hormonal regulation of the c-fms proto-oncogene in breast cancer cells is mediated by a composite glucocorticoid response element. J Cell Biochem 2002; 85: 10-23.
    • (2002) J Cell Biochem , vol.85 , pp. 10-23
    • Flick, M.M.1    Sapi, E.2    Kacinski, B.M.3
  • 25
    • 0035911230 scopus 로고    scopus 로고
    • Inflammatory Cells and cancer: Think different!
    • Coussens LM, Werb Z. Inflammatory Cells and cancer: think different! J Exp Med 2001; 193: 23F.
    • (2001) J Exp Med , vol.193
    • Coussens, L.M.1    Werb, Z.2
  • 26
    • 0036329210 scopus 로고    scopus 로고
    • Correlation between vascular endothelial growth factor, angiogenesis, and tumor-associated macrophages in invasive ductal breast carcinoma
    • Valkovic T, Dobrila F, Melato M et al. Correlation between vascular endothelial growth factor, angiogenesis, and tumor-associated macrophages in invasive ductal breast carcinoma. Virchows Arch 2002; 440: 583-8.
    • (2002) Virchows Arch , vol.440 , pp. 583-588
    • Valkovic, T.1    Dobrila, F.2    Melato, M.3
  • 28
    • 0035911221 scopus 로고    scopus 로고
    • Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy
    • Lin EY, Nguyen AV, Russell RG et al. Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med 2001; 193: F23-6.
    • (2001) J Exp Med , vol.193
    • Lin, E.Y.1    Nguyen, A.V.2    Russell, R.G.3
  • 29
    • 0025821436 scopus 로고
    • FMS (CSF-1 receptor) and CSF-1 transcripts and protein are expressed by human breast carcinomas in vivo and in vitro
    • Kacinski BM, Scata KA, Carter D et al. FMS (CSF-1 receptor) and CSF-1 transcripts and protein are expressed by human breast carcinomas in vivo and in vitro. Oncogene 1991; 6: 941-52.
    • (1991) Oncogene , vol.6 , pp. 941-952
    • Kacinski, B.M.1    Scata, K.A.2    Carter, D.3
  • 30
    • 0030968146 scopus 로고    scopus 로고
    • Recognition of activated CSF-1 receptor in breast carcinomas by a tyrosine 723 phosphospecific antibody
    • Flick MB, Sapi E, Perrotta PL et al. Recognition of activated CSF-1 receptor in breast carcinomas by a tyrosine 723 phosphospecific antibody. Oncogene 1997; 14: 2553-61.
    • (1997) Oncogene , vol.14 , pp. 2553-2561
    • Flick, M.B.1    Sapi, E.2    Perrotta, P.L.3
  • 31
    • 0028902228 scopus 로고
    • CSF-1 and its receptor in ovarian, endometrial and breast cancer
    • Kacinski BM. CSF-1 and its receptor in ovarian, endometrial and breast cancer. Ann Med 1995; 27: 79-85.
    • (1995) Ann Med , vol.27 , pp. 79-85
    • Kacinski, B.M.1
  • 32
    • 0035135492 scopus 로고    scopus 로고
    • The activated macrophage colony-stimulating factor (CSF-1) receptor as a predictor of poor outcome in advanced epithelial ovarian carcinoma
    • Toy EP, Chambers JT, Kacinski BM et al. The activated macrophage colony-stimulating factor (CSF-1) receptor as a predictor of poor outcome in advanced epithelial ovarian carcinoma. Gynecol Oncol 2001; 80: 194-200.
    • (2001) Gynecol Oncol , vol.80 , pp. 194-200
    • Toy, E.P.1    Chambers, J.T.2    Kacinski, B.M.3
  • 33
    • 0031872766 scopus 로고    scopus 로고
    • Prognostic significance of colony-stimulating factor receptor expression in ipsilateral breast cancer recurrence
    • Maher MG, Sapi E, Turner B et al. Prognostic significance of colony-stimulating factor receptor expression in ipsilateral breast cancer recurrence. Clin Cancer Res 1998; 4: 1851-6.
    • (1998) Clin Cancer Res , vol.4 , pp. 1851-1856
    • Maher, M.G.1    Sapi, E.2    Turner, B.3
  • 34
    • 0026678150 scopus 로고
    • M-CSF (monocyte colony stimulating factor) and M-CSF receptor expression by breast tumour cells: M-CSF mediated recruitment of tumour infiltrating monocytes?
    • Tang R, Beuvon F, Ojeda M et al. M-CSF (monocyte colony stimulating factor) and M-CSF receptor expression by breast tumour cells: M-CSF mediated recruitment of tumour infiltrating monocytes? J Cell Biochem 1992; 50: 350-6.
    • (1992) J Cell Biochem , vol.50 , pp. 350-356
    • Tang, R.1    Beuvon, F.2    Ojeda, M.3
  • 35
    • 0031015002 scopus 로고    scopus 로고
    • CSF-1 and its receptor in breast carcinomas and neoplasms of the female reproductive tract
    • Kacinski BM. CSF-1 and its receptor in breast carcinomas and neoplasms of the female reproductive tract. Mol Reprod Dev 1997; 46: 71-4.
    • (1997) Mol Reprod Dev , vol.46 , pp. 71-74
    • Kacinski, B.M.1
  • 36
    • 0034483990 scopus 로고    scopus 로고
    • The constitutive production of colony stimulating factor 1 by invasive human breast cancer cells
    • Yee LD, Liu L. The constitutive production of colony stimulating factor 1 by invasive human breast cancer cells. Anticancer Res 2000; 20: 4379-83.
    • (2000) Anticancer Res , vol.20 , pp. 4379-4383
    • Yee, L.D.1    Liu, L.2
  • 37
    • 0036096884 scopus 로고    scopus 로고
    • Circulating macrophage colony stimulating factor as a marker of tumour progression
    • McDermott RS, Deneux L, Mosseri V et al. Circulating macrophage colony stimulating factor as a marker of tumour progression. Eur Cytokine Netw 2002; 13: 121-27.
    • (2002) Eur Cytokine Netw , vol.13 , pp. 121-127
    • McDermott, R.S.1    Deneux, L.2    Mosseri, V.3
  • 38
    • 0036039366 scopus 로고    scopus 로고
    • The role of bisphosphonates in breast cancer management: Review article
    • Pickering LM, Mansi JL. The role of bisphosphonates in breast cancer management: review article. Curr Med Res Opin 2002; 18: 284-95.
    • (2002) Curr Med Res Opin , vol.18 , pp. 284-295
    • Pickering, L.M.1    Mansi, J.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.