Cardiotrophin-1 induces sarcoplasmic reticulum Ca2+ leak and arrhythmogenesis in adult rat ventricular myocytes

Cardiovascular Research

Volumn 96, Issue 1, 2012, Pages 81-89

  Ruiz Hurtado, Gema ^a,b   Gómez Hurtado, Nieves ^c   Fernández Velasco, María ^d   Calderón, Eva ^e   Smani, Tarik ^e   Ordoñez, Antonio ^e   Cachofeiro, Victoria ^c   Boscá, Lisardo ^f   Díez, Javier ^g   Gómez, Ana María ^a   Delgado, Carmen ^c,h  

^a INSERM   (France)

^b HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^d HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^e HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^f INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

^g UNIVERSITY OF NAVARRA   (Spain)

^h CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

Ca2+ handling; CaMKII; Cardiomyocytes; Cardiotrophin 1; PKA

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CHANNEL L TYPE; CALCIUM ION; CARDIOTROPHIN 1; CYCLIC AMP DEPENDENT PROTEIN KINASE;

ANIMAL CELL; ARRHYTHMOGENESIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIASTOLE; ENZYME ACTIVITY; HEART MUSCLE CELL; IMMUNOBLOTTING; MALE; MUSCLE FIBER CONTRACTION; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SARCOPLASMIC RETICULUM;

ANIMALS; ARRHYTHMIAS, CARDIAC; CALCIUM; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOKINES; DIASTOLE; MALE; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; RATS; RATS, WISTAR; SARCOPLASMIC RETICULUM;

EID: 84866717548     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvs234     Document Type: Article

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