SHP2-mediated signaling cascade through gp130 is essential for LIF-dependent ICaL, [Ca2+]i transient, and APD increase in cardiomyocytes

Journal of Molecular and Cellular Cardiology

Volumn 43, Issue 6, 2007, Pages 710-716

  Hagiwara, Yoko ^a   Miyoshi, Shunichiro ^a   Fukuda, Keiichi ^a   Nishiyama, Nobuhiro ^a   Ikegami, Yukinori ^a   Tanimoto, Kojiro ^a   Murata, Mitsushige ^a   Takahashi, Eiichi ^a   Shimoda, Kouji ^a   Hirano, Toshio ^b   Mitamura, Hideo ^c   Ogawa, Satoshi ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c SAISEIKAI CENTRAL HOSPITAL   (Japan)

Author keywords

Fluo 4; IL 6; Ion channel; L type Ca2+ current; Leukemia inhibitory factor (LIF); Patch clamp; SHP2

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CALCIUM CHANNEL L TYPE; GLYCOPROTEIN GP 130; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; ION CHANNEL; JANUS KINASE; LEUKEMIA INHIBITORY FACTOR; PROTEIN TYROSINE PHOSPHATASE SHP 2; STAT3 PROTEIN;

ACTION POTENTIAL; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; HEART MUSCLE; MOUSE; MUSCLE ACTION POTENTIAL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ACTION POTENTIALS; ANIMALS; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CYTOKINE RECEPTOR GP130; FLAVONOIDS; HUMANS; INTERLEUKIN-6; LEUKEMIA INHIBITORY FACTOR; MICE; MYOCYTES, CARDIAC; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11;

MUS;

EID: 36448956446     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2007.09.004     Document Type: Article

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