Extrapancreatic Autoantibody Profiles in Type I Diabetes

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Burbelo, Peter D ^a   Lebovitz, Evan E ^a   Bren, Kathleen E ^a   Bayat, Ahmad ^a   Paviol, Scott ^b   Wenzlau, Janet M ^c   Barriga, Katherine J ^c   Rewers, Marian ^c   Harlan, David M ^b   Iadarola, Michael J ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF COLORADO DENVER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE 4B; ADENOSINE TRIPHOSPHATASE 4B ANTIBODY; AUTOANTIBODY; CYTOKINE; GLUTAMATE DECARBOXYLASE 65 ANTIBODY; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN A2 ANTIBODY; IMMUNOGLOBULIN A2 BETA ANTIBODY; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; PROTEIN KCNRG; PROTEIN S100B; THYROID PEROXIDASE; THYROID PEROXIDASE ANTIBODY; UNCLASSIFIED DRUG;

ANTIBODY DETECTION; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; HIGH RISK PATIENT; HUMAN; IMMUNOREACTIVITY; INSULIN DEPENDENT DIABETES MELLITUS; NUCLEOTIDE SEQUENCE; ONSET AGE; PANCREAS ISLET BETA CELL; SINGLE BLIND PROCEDURE;

ADENOSINE TRIPHOSPHATASES; AUTOANTIBODIES; CASE-CONTROL STUDIES; COHORT STUDIES; DIABETES MELLITUS, TYPE 1; FEMALE; HUMANS; IMMUNOPRECIPITATION; IODIDE PEROXIDASE; ISLETS OF LANGERHANS; LUCIFERASES; NERVE GROWTH FACTORS; POTASSIUM CHANNELS; S100 PROTEINS; STOMACH; TRANSGLUTAMINASES;

EID: 84866705297     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0045216     Document Type: Article

References (40)

1. Bluestone JA, Herold K, Eisenbarth G, (2010) Genetics, pathogenesis and clinical interventions in type 1 diabetes. Nature 464: 1293-1300.
2. Bingley PJ, (2010) Clinical applications of diabetes antibody testing. J Clin Endocrinol Metab 95: 25-33.
3. Pihoker C, Gilliam LK, Hampe CS, Lernmark A, (2005) Autoantibodies in diabetes. Diabetes 54 Suppl 2: S52-61.
4. Achenbach P, Koczwara K, Knopff A, Naserke H, Ziegler AG, et al. (2004) Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to type 1 diabetes. J Clin Invest 114: 589-597.
5. Achenbach P, Warncke K, Reiter J, Naserke HE, Williams AJ, et al. (2004) Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics. Diabetes 53: 384-392.
6. Barker JM, Barriga KJ, Yu L, Miao D, Erlich HA, et al. (2004) Prediction of autoantibody positivity and progression to type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY). J Clin Endocrinol Metab 89: 3896-3902.
7. Bingley PJ, Bonifacio E, Williams AJ, Genovese S, Bottazzo GF, et al. (1997) Prediction of IDDM in the general population: strategies based on combinations of autoantibody markers. Diabetes 46: 1701-1710.
8. Krischer JP, Cuthbertson DD, Yu L, Orban T, Maclaren N, et al. (2003) Screening strategies for the identification of multiple antibody-positive relatives of individuals with type 1 diabetes. J Clin Endocrinol Metab 88: 103-108.
9. Mayr A, Schlosser M, Grober N, Kenk H, Ziegler AG, et al. (2007) GAD autoantibody affinity and epitope specificity identify distinct immunization profiles in children at risk for type 1 diabetes. Diabetes 56: 1527-1533.
10. Orban T, Sosenko JM, Cuthbertson D, Krischer JP, Skyler JS, et al. (2009) Pancreatic islet autoantibodies as predictors of type 1 diabetes in the Diabetes Prevention Trial-Type 1. Diabetes Care 32: 2269-2274.
11. Bingley PJ, Christie MR, Bonifacio E, Bonfanti R, Shattock M, et al. (1994) Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives. Diabetes 43: 1304-1310.
12. Betterle C, Zanette F, Pedini B, Presotto F, Rapp LB, et al. (1984) Clinical and subclinical organ-specific autoimmune manifestations in type 1 (insulin-dependent) diabetic patients and their first-degree relatives. Diabetologia 26: 431-436.
13. De Block CE, De Leeuw IH, Van Gaal LF, (1999) High prevalence of manifestations of gastric autoimmunity in parietal cell antibody-positive type 1 (insulin-dependent) diabetic patients. The Belgian Diabetes Registry. J Clin Endocrinol Metab 84: 4062-4067.
14. Burek CL, Rose NR, Guire KE, Hoffman WH, (1990) Thyroid autoantibodies in black and in white children and adolescents with type 1 diabetes mellitus and their first degree relatives. Autoimmunity 7: 157-167.
15. Radetti G, Paganini C, Gentili L, Bernasconi S, Betterle C, et al. (1995) Frequency of Hashimoto's thyroiditis in children with type 1 diabetes mellitus. Acta Diabetol 32: 121-124.
16. Landin-Olsson M, Karlsson FA, Lernmark A, Sundkvist G, (1992) Islet cell and thyrogastric antibodies in 633 consecutive 15- to 34-yr-old patients in the diabetes incidence study in Sweden. Diabetes 41: 1022-1027.
17. Seissler J, Schott M, Boms S, Wohlrab U, Ostendorf B, et al. (1999) Autoantibodies to human tissue transgutaminase identify silent coeliac disease in Type I diabetes. Diabetologia 42: 1440-1441.
18. Lampasona V, Bonfanti R, Bazzigaluppi E, Venerando A, Chiumello G, et al. (1999) Antibodies to tissue transglutaminase C in type I diabetes. Diabetologia 42: 1195-1198.
19. Barker JM, Yu J, Yu L, Wang J, Miao D, et al. (2005) Autoantibody "subspecificity" in type 1 diabetes: risk for organ-specific autoimmunity clusters in distinct groups. Diabetes Care 28: 850-855.
20. Umpierrez GE, Latif KA, Murphy MB, Lambeth HC, Stentz F, et al. (2003) Thyroid dysfunction in patients with type 1 diabetes: a longitudinal study. Diabetes Care 26: 1181-1185.
21. Hanukoglu A, Mizrachi A, Dalal I, Admoni O, Rakover Y, et al. (2003) Extrapancreatic autoimmune manifestations in type 1 diabetes patients and their first-degree relatives: a multicenter study. Diabetes Care 26: 1235-1240.
22. Triolo TM, Armstrong TK, McFann K, Yu L, Rewers MJ, et al. (2011) Additional autoimmune disease found in 33% of patients at type 1 diabetes onset. Diabetes Care 34: 1211-1213.
23. De Block CE, De Leeuw IH, Bogers JJ, Pelckmans PA, Ieven MM, et al. (2003) Autoimmune gastropathy in type 1 diabetic patients with parietal cell antibodies: histological and clinical findings. Diabetes Care 26: 82-88.
24. De Block CE, De Leeuw IH, Rooman RP, Winnock F, Du Caju MV, et al. (2000) Gastric parietal cell antibodies are associated with glutamic acid decarboxylase-65 antibodies and the HLA DQA1*0501-DQB1*0301 haplotype in Type 1 diabetes mellitus. Belgian Diabetes Registry. Diabet Med 17: 618-622.
25. Burbelo PD, Ching KH, Bren KE, Iadarola MJ, (2011) Searching for biomarkers: humoral response profiling with luciferase immunoprecipitation systems. Expert Rev Proteomics 8: 309-316.
26. Liu E, Eisenbarth GS, (2007) Accepting clocks that tell time poorly: fluid-phase versus standard ELISA autoantibody assays. Clin Immunol 125: 120-126.
27. Burbelo PD, Hirai H, Issa AT, Kingman A, Lernmark A, et al. (2010) Comparison of radioimmunoprecipitation with luciferase immunoprecipitation for autoantibodies to GAD65 and IA-2beta. Diabetes Care 33: 754-756.
28. Burbelo PD, Hirai H, Leahy H, Lernmark A, Ivarsson SA, et al. (2008) A new luminescence assay for autoantibodies to mammalian cell-prepared insulinoma-associated protein 2. Diabetes Care 31: 1824-1826.
29. Wenzlau JM, Juhl K, Yu L, Moua O, Sarkar SA, et al. (2007) The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes. Proc Natl Acad Sci U S A 104: 17040-17045.
30. Burbelo PD, Seam N, Groot S, Ching KH, Han BL, et al. (2010) Rapid induction of autoantibodies during ARDS and septic shock. J Transl Med 8: 97.
31. Ching KH, Burbelo PD, Tipton C, Wei C, Petri M, et al. (2012) Two major autoantibody clusters in systemic lupus erythematosus. PLoS One 7: e32001.
32. Burbelo PD, Browne SK, Sampaio EP, Giaccone G, Zaman R, et al. (2010) Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia. Blood 116: 4848-4858.
33. Burbelo PD, Ching KH, Klimavicz CM, Iadarola MJ, (2009) Antibody profiling by Luciferase Immunoprecipitation Systems (LIPS). J Vis Exp.
34. Wenzlau JM, Liu Y, Yu L, Moua O, Fowler KT, et al. (2008) A common nonsynonymous single nucleotide polymorphism in the SLC30A8 gene determines ZnT8 autoantibody specificity in type 1 diabetes. Diabetes 57: 2693-2697.
35. Barker JM, (2006) Clinical review: Type 1 diabetes-associated autoimmunity: natural history, genetic associations, and screening. J Clin Endocrinol Metab 91: 1210-1217.
36. Wenzlau JM, Gardner TJ, Frisch LM, Davidson HW, Hutton JC, (2011) Development of a novel autoantibody assay for autoimmune gastritis in type 1 diabetic individuals. Diabetes Metab Res Rev 27: 887-890.
37. Plagnol V, Howson JM, Smyth DJ, Walker N, Hafler JP, et al. (2011) Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. PLoS Genet 7: e1002216.
38. Alimohammadi M, Dubois N, Skoldberg F, Hallgren A, Tardivel I, et al. (2009) Pulmonary autoimmunity as a feature of autoimmune polyendocrine syndrome type 1 and identification of KCNRG as a bronchial autoantigen. Proc Natl Acad Sci U S A 106: 4396-4401.
39. Winer S, Tsui H, Lau A, Song A, Li X, et al. (2003) Autoimmune islet destruction in spontaneous type 1 diabetes is not beta-cell exclusive. Nat Med 9: 198-205.
40. Lampasona V, Schlosser M, Mueller PW, Williams AJ, Wenzlau JM, et al. (2011) Diabetes Antibody Standardization Program: First Proficiency Evaluation of Assays for Autoantibodies to Zinc Transporter 8. Clin Chem.