Peptide sequences mediating tropism to intact blood-brain barrier: An in vivo biodistribution study using phage display

Peptides

Volumn 38, Issue 1, 2012, Pages 172-180

  Smith, Mathew W ^a   Al Jayyoussi, Ghaith ^a   Gumbleton, Mark ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Biodistribution; Blood brain barrier; Brain tropism; Peptide; Phage display; Pharmacokinetics

Indexed keywords

PEPTIDE;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; BRAIN PERFUSION; BRAIN TISSUE; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG TISSUE LEVEL; GRAY MATTER; IN VIVO STUDY; KIDNEY; LARGE INTESTINE; LIVER; LUNG; MALE; MICROVASCULATURE; MUSCLE; NONHUMAN; PHARMACOKINETICS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; SMALL INTESTINE; SPLEEN; TESTIS; TROPISM; VIRION; WHITE MATTER;

AMINO ACID MOTIFS; ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; MALE; PEPTIDE LIBRARY; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION;

RATTUS;

EID: 84866652293     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2012.06.019     Document Type: Article

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