Nemaline Myopathy-Related Skeletal Muscle α-Actin (ACTA1) Mutation, Asp286Gly, Prevents Proper Strong Myosin Binding and Triggers Muscle Weakness

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Ochala, Julien ^a   Ravenscroft, Gianina ^b   Laing, Nigel G ^b   Nowak, Kristen J ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ALPHA ACTIN; ASPARTIC ACID; GLYCINE; MYOSIN; MYOSIN ADENOSINE TRIPHOSPHATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; COMPUTER SIMULATION; CONTROLLED STUDY; EXTENSOR DIGITORUM LONGUS MUSCLE; GENE; GENE MUTATION; GENETIC ASSOCIATION; MALE; MECHANICS; MOUSE; MUSCLE CELL; MUSCLE CONTRACTION; MUSCLE FORCE; MUSCLE STIFFNESS; MUSCLE WEAKNESS; NEMALINE MYOPATHY; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SMOOTH MUSCLE ALPHA ACTIN GENE; TRANSGENIC MOUSE;

ACTINS; ANIMALS; BIOMECHANICS; MALE; MICE; MICE, TRANSGENIC; MODELS, MOLECULAR; MUSCLE CONTRACTION; MUSCLE WEAKNESS; MUSCLE, SKELETAL; MYOPATHIES, NEMALINE; MYOSINS; POINT MUTATION;

MUS MUSCULUS;

EID: 84866645945     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0045923     Document Type: Article

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