Actin nemaline myopathy mouse reproduces disease, suggests other actin disease phenotypes and provides cautionary note on muscle transgene expression

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Ravenscroft, Gianina ^a,b   Jackaman, Connie ^a   Sewry, Caroline A ^c   McNamara, Elyshia ^a   Squire, Sarah E ^d   Potter, Allyson C ^d   Papadimitriou, John ^b   Griffiths, Lisa M ^e   Bakker, Anthony J ^b   Davies, Kay E ^d   Laing, Nigel G ^a   Nowak, Kristen J ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c ROBERT JONES AND AGNES HUNT ORTHOPAEDIC HOSPITAL   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e ROYAL PERTH HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTIN; ENHANCED GREEN FLUORESCENT PROTEIN; MYOSIN HEAVY CHAIN; ACTIN; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; EXTENSOR DIGITORUM LONGUS MUSCLE; GASTROCNEMIUS MUSCLE; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; MOUSE; MUSCLE CONTRACTION; MUSCLE SPINDLE; MUSCLE WEAKNESS; NEMALINE MYOPATHY; NONHUMAN; PHENOTYPE; QUADRICEPS FEMORIS MUSCLE; RELAXATION TIME; SARCOMERE; SOLEUS MUSCLE; TRANSGENIC MOUSE; WILD TYPE; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; DISEASE MODEL; GENETICS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SKELETAL MUSCLE; TRANSGENE; ULTRASTRUCTURE;

ACTINS; ANIMALS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GREEN FLUORESCENT PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUSCLE CONTRACTION; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; MYOPATHIES, NEMALINE; MYOSIN HEAVY CHAINS; PHENOTYPE; RECOMBINANT FUSION PROTEINS; TRANSGENES;

EID: 83055164378     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028699     Document Type: Article

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