Disrupted myosin cross-bridge cycling kinetics triggers muscle weakness in nebulin-related myopathy

FASEB Journal

Volumn 25, Issue 6, 2011, Pages 1903-1913

  Ochala, Julien ^a   Lehtokari, Vilma Lotta ^b   Iwamoto, Hiroyuki ^c   Li, Meishan ^a   Feng, Han Zhong ^d   Jin, Jian Ping ^d   Yagi, Naoto ^c   Wallgren Pettersson, Carina ^b   Pénisson Besnier, Isabelle ^e   Larsson, Lars ^a,f  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY OF HELSINKI   (Finland)

^c JAPAN SYNCHROTRON RADIATION RESEARCH INSTITUTE   (Japan)

^d WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e ANGERS UNIVERSITY HOSPITAL   (France)

^f PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Congenital myopathy; Tropomyosin activation

Indexed keywords

ACTIN; MYOSIN; NEBULIN; TROPOMYOSIN;

ACTIN MYOSIN INTERACTION; ADULT; ARTICLE; CASE REPORT; CELL ADHESION; CELL MEMBRANE PERMEABILITY; GENE DISRUPTION; GENE MUTATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MUSCLE BIOPSY; MUSCLE CELL; MUSCLE CONTRACTION; MUSCLE FORCE; MUSCLE ISOMETRIC CONTRACTION; MUSCLE WEAKNESS; NEMALINE MYOPATHY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; THIN FILAMENT; X RAY DIFFRACTION;

ADULT; GENE EXPRESSION REGULATION; HUMANS; KINETICS; MALE; MIDDLE AGED; MUSCLE PROTEINS; MUSCLE WEAKNESS; MUSCLE, SKELETAL; MUTATION; MYOPATHIES, NEMALINE; MYOSINS; X-RAY DIFFRACTION;

EID: 79957918034     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-176727     Document Type: Article

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