Mouse models of dominant ACTA1 disease recapitulate human disease and provide insight into therapies

Brain

Volumn 134, Issue 4, 2011, Pages 1101-1115

  Ravenscroft, Gianina ^a,b   Jackaman, Connie ^a   Bringans, Scott ^c   Papadimitriou, John M ^b   Griffiths, Lisa M ^d   McNamara, Elyshia ^a   Bakker, Anthony J ^b   Davies, Kay E ^e   Laing, Nigel G ^a   Nowak, Kristen J ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c PROTEOMICS INTERNATIONAL   (Australia)

^d ROYAL PERTH HOSPITAL   (Australia)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

ACTA1; animal models; dominant; nemaline; pathology

Indexed keywords

ALPHA ACTININ 1; ALPHA CRYSTALLIN; DESMIN;

ANIMAL EUTHANASIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ELECTRON MICROSCOPY; GENE MUTATION; GRIP STRENGTH; HEMIZYGOSITY; HOMOZYGOSITY; IMMOBILIZATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIFESPAN; MASS SPECTROMETRY; MOUSE; MUSCLE CONTRACTILITY; MYOPATHY; NONHUMAN; PRIORITY JOURNAL; PROGENY; SKELETAL MUSCLE; TRANSGENIC MOUSE; WILD TYPE;

EID: 79953663838     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awr004     Document Type: Article

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