Increased Expression of the dsRNA-Activated Protein Kinase PKR in Breast Cancer Promotes Sensitivity to Doxorubicin

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Bennett, Richard L ^a   Carruthers, Aubrey L ^a   Hui, Teng ^a   Kerney, Krystal R ^a   Liu, Xiangfei ^a   May, W Stratford ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; DOXORUBICIN; HYDROGEN PEROXIDE; INITIATION FACTOR 2ALPHA; PROTEIN KINASE R; SALUBRINAL; SMALL INTERFERING RNA;

ARTICLE; BREAST CANCER; BREAST DYSPLASIA; BREAST HYPERPLASIA; CANCER CELL; CANCER STAGING; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG SENSITIVITY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; PRECANCER; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; UPREGULATION;

ANTIBIOTICS, ANTINEOPLASTIC; BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; DOXORUBICIN; EIF-2 KINASE; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PROTEIN KINASE INHIBITORS; RNA INTERFERENCE; RNA, DOUBLE-STRANDED; RNA, SMALL INTERFERING;

EID: 84866636092     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046040     Document Type: Article

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