Interferon-responsive protein kinase (p68) and proliferating cell nuclear antigen are inversely distributed in head and neck squamous cell carcinoma

Tumor Biology

Volumn 19, Issue 1, 1997, Pages 52-59

  Haines III, G Kenneth ^a,b   Panos, Ralph J ^a   Bak, Philip M ^a   Brown, Tim ^a   Zielinski, Mike ^a   Leyland, John ^a   Radosevich, James A ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NORTHWESTERN MEMORIAL HOSPITAL   (United States)

Author keywords

Cell proliferation; Head and neck tumors; Proliferating cell nuclear antigen; Protein kinase, interferon responsive; Squamous cell carcinoma

Indexed keywords

CYCLINE; INTERFERON; MONOCLONAL ANTIBODY; PROTEIN KINASE;

ADULT; AGED; ARTICLE; CANCER SURVIVAL; CELL PROLIFERATION; ENZYME LOCALIZATION; HEAD AND NECK CARCINOMA; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA;

EID: 0031458299     PISSN: 10104283     EISSN: None     Source Type: Journal    
DOI: 10.1159/000029974     Document Type: Article

References (33)

1. Haines GK, Ghadge G, Radosevich JA: Expression of p68 protein kinase as recognized by the monoclonal antibody TJ4C4 during human fetal development. Tumor Biol 1993;14: 95-104.
2. Haines GK, Ghadge G, Thimmappaya B, Radosevich JA: Expression of the protein kinase p68 recognized by the monoclonal antibody TJ4C4 in human lung neoplasms. Virchow Arch B Cell Pathol 1992;62:151- 158.
3. Haines GK, Ghadge G, Becker S, Kies M, Pelzer H, Thimmappaya B, Radosevich JA: Correlation of the expression of double-stranded RNA-dependent protein kinase (p68) with differentiation in head and neck squamous cell carcinoma. Virchow Arch B Cell Pathol 1993; 63:289-295.
4. Haines GK III, Becker S, Ghadge G, Kies M, Pelzer H, Radosevich JA: Expression of the double-stranded RNA-dependent protein kinase (p68) in squamous cell carcinoma of the head and neck region. Arch Otolaryngol Head Neck Surg 1993;119: 1142-1147.
5. Singh CJ, Haines GK, Talamonti M, Radosevich JA: Expression of p68 in human colon cancer. Tumor Biol 1995;16:281-289.
6. Chong KL, Feng L, Schappert K, Meurs E, Donahue TF, Friesen JD, Hovanessian AG, Williams RG: Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator, GCN2. EMBO J 1992;11:1553- 1562.
7. Koromilas AE, Roy S, Barber GN, Katze MG, Sonenberg N: Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase. Science 1992;257: 1685-1688.
8. Meurs EF, Galabru J, Barber GN, Katze MG, Hovanessian AG, Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase. Proc Natl Acad Sci USA 1993;90:232- 236.
9. Clemens MJ, McNurlan MA: Regulation of cell proliferation and differentiation by interferons. Biochem J 1985;226:345-360.
10. Hermanek P, Sobin LH (eds). TNM Classification of Malignant Tumors, ed 4. UICC, International Union Against Cancer. Berlin, Springer, 1987.
11. Jakobsson PA: Histologic grading of malignancy and prognosis in glottic carcinoma of the larynx. Workshop No 14; in Alberti PW, Bryce DP (eds). Centennial Conference on Laryngeal Cancer. New York, Appleton-Century-Crofts, 1976, pp 847- 852.
12. Radosevich JA, Ghadge GD, Haines GK, Malhotra P, Thimmappaya B: Characterization of the mouse monoclonal antibody TJ4C4 directed at human p68 kinase. Tumor Biol 1994;15:255-262.
13. Merchanthaler I, Stankovics J, Gallays F: A highly sensitive one-step method for silver intensification of the nickel-diaminobenzidine end-product of peroxidase reaction. J Histochem Cytochem 1989;37: 1563-1565.
14. Parker SL, Tong T, Belden S, Winger PA: Cancer Statistics, 1996. CA. Cancer J Clin 1996;65:5-27.
15. Johansen LV, Mestre M, Overgaard J: Carcinoma of the naso-pharynx: Analysis of treatment results in 167 consecutively admitted patients. Head Neck 1992;14:200-207.
16. Soo KC, Spiro RH, King W, Harvey W, Strong EW: Squamous carcinoma of the gums. Am J Surg 1988; 156:281-285.
17. Kearsley JH, Bryson G, Battistutta D, Collins RJ: Prognostic importance of cellular DNA content in head-and-neck squamous-cell cancers. A comparison of retrospective and prospective series. Int J Cancer 1991;47:31-37.
18. Oku N, Shimada K, Ito H: Ha-ras oncogene product in human oral squamous cell carcinoma. Kobe J Med Sci 1989;35:277-286.
19. Rikimaru K, Todokoro K, Yamamoto T, Enomoto S, Tsuchida N: Gene amplification and overexpression of epidermal growth factor receptor in squamous cell carcinoma of the head and neck. Head Neck 1992;14:8-13.
20. Watling DL, Gown AM, Coltrera MD: Overexpression of p53 in head and neck cancer. Head Neck 1992; 14:437-444.
21. Meurs E, Chong K, Galabru J, Shaun N, Thomas T, Kerr IM, Williams BRG, Hovanessian A: Molecular cloning and characterization of the human double-stranded RNA- activated protein kinase induced by interferon. Cell 1990;62:379-390.
22. Berry MJ, Knutson GS, Lasky SR, Munemitsu SM, Sameul CE: Mechanism of interferon action: Purification and substrate specificities of the double-stranded RNA-dependent protein kinase from untreated and interferon-treated mouse fibroblasts. J Biol Chem 1985;260: 11240-11247.
23. Colthurst DR, Campbell DG, Proud CG: Structure and regulation of eukaryotic initiation factor eIF-2: Sequence of the site in the a subunit phosphorylated by the haem-controlled repressor and by the double- stranded RNA-activated inhibitor. Eur J Biochem 1987;166:357-363.
24. Haines GK, Cajulis R, Hayden R, Duda R, Talamonti M, Radosevich JA: Expression of the double- stranded RNA-dependent protein kinase (p68) in human breast tissues. Tumor Biol 1996;17:5-12.
25. Gresser I: Antitumor effects of interferon. Acta Oncol 1989;28:347- 353.
26. Jaramillo ML, Abraham N, Bell JC: The interferon system: A review with emphasis on the role of PKR in growth control. Cancer Invest 1995; 13:327-338.
27. Petryshyn R, Chen JJ, London IM: Growth-related expression of a double-stranded RNA-dependent protein kinase in 3T3 cells, J Biol Chem 1984;259:14736-14742
28. Lee SB, Melkova Z, Yan W, Williams BRG, Hovanessian AG, Esteban M: The interferon-induced double-stranded RNA-activated human p68 protein kinase potently inhibits protein synthesis in cultured cells. Virology 1993;192:380-385
29. Lee SB, Esteban M: The interferon- induced double-stranded RNA-activated protein kinase induces apoptosis. Virology 1994;199:491-496.
30. Lampe HB: DNA analysis of head and neck squamous cell carcinoma by flow cytometry. Laryngoscope 1993;103:637-644.
31. Robbins BA, de la Vega D, Ogata K, Tan EM, Nakamura RM: Immunohistochemical detection of proliferating cell nuclear antigen in solid human malignancies Arch Pathol Lab Med 1987;111:841-845.
32. Takasaki Y, Deng J-S, Tan EM: A nuclear antigen associated with cell proliferation and blast transformation: Its distribution in synchronized cells. J Exp Med 1981;154: 1899-1909.
33. Tsuji T, Mimura Y, Wen S, Li X, Kanekawa A, Sasaki K, Shinozaki F: The significance of PCNA and p53 in some oral tumors. Int J Oral Maxillofac Surg 1995;24:221-225.