Rebuilding the balance of STAT1 and STAT3 signalings by fusaruside, a cerebroside compound, for the treatment of T-cell-mediated fulminant hepatitis in mice

Biochemical Pharmacology

Volumn 84, Issue 9, 2012, Pages 1164-1173

  Wu, Xing Xin ^a   Sun, Yang ^a   Guo, Wen Jie ^a   Gu, Yan Hong ^b   Wu, Xue Feng ^a   Tan, Ren Xiang ^a   Xu, Qiang ^a  

^a NANJING UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Concanavalin A; Fusaruside; Liver injury; STAT1; STAT3

Indexed keywords

CEREBROSIDE; CONCANAVALIN A; CYCLOSPORIN A; CYTOKINE; FUSARUSIDE; PROTEIN BCL XL; STAT1 PROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CELL PROTECTION; CELLULAR IMMUNITY; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; ENDOPHYTE; FUSARIUM; HEPATITIS; HISTOPATHOLOGY; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TH1 CELL; TH17 CELL; TH2 CELL;

ANIMALS; ANTIGENS, CD4; BCL-X PROTEIN; CELL PROLIFERATION; CEREBROSIDES; CONCANAVALIN A; CYTOKINES; FEMALE; FUSARIUM; HEPATITIS, ANIMAL; LIVER; LIVER FAILURE, ACUTE; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; NATURAL KILLER T-CELLS; SIGNAL TRANSDUCTION; SPLEEN; STAT1 TRANSCRIPTION FACTOR; STAT2 TRANSCRIPTION FACTOR; T-LYMPHOCYTES;

EID: 84866612596     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.08.006     Document Type: Article

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