Beyond fat grafting: What adipose tissue can teach us about the molecular mechanisms of human aging

Annals of Plastic Surgery

Volumn 69, Issue 4, 2012, Pages 489-492

  Stransky, Carrie A ^a   Hsu, Vivian M ^a   Dierov, Raia ^a   Hoover, William J ^a   Donahue, Greg ^b   Bucky, Louis P ^a   Percec, Ivona ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Adipocyte; Adipose tissue; Aging; Fat grafting; Genetics; Genomic; Stromal vascular fraction; SVF; Transcriptional profiling

Indexed keywords

RNA; TRANSCRIPTOME;

ADULT; AGING; ARTICLE; BIOLOGICAL MODEL; DNA MICROARRAY; FEMALE; GENE EXPRESSION PROFILING; GENETIC EPIGENESIS; GENETICS; HUMAN; LIPECTOMY; MALE; MIDDLE AGED; PHYSIOLOGY; SUBCUTANEOUS FAT;

ADULT; AGING; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION PROFILING; HUMANS; LIPECTOMY; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA; SUBCUTANEOUS FAT; TRANSCRIPTOME;

EID: 84866606945     PISSN: 01487043     EISSN: None     Source Type: Journal    
DOI: 10.1097/SAP.0b013e31824c0e43     Document Type: Conference Paper

References (29)

1. Dept. of Health and Human Services. Administration on Aging. 2011, U.S. Census Bureau.
2. Bucky LP, Percec I. The science of autologous fat grafting: views on current and future approaches to neoadipogenesis. Aesthet Surg J. 2008;28:313-321; quiz 322-4.
3. Beeson W, Woods E, Agha R. Tissue engineering, regenerative medicine, and rejuvenation in 2010: the role of adipose-derived stem cells. Facial Plast Surg. 2011;27:378-387.
4. Sommer B, Sattler G. Current concepts of fat graft survival: histology of aspirated adipose tissue and review of the literature. Dermatol Surg. 2000; 26:1159-1166.
5. Oberdoerffer P, Michan S, McVay M, et al. SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell. 2008;135:907-918.
6. Peterbauer-Scherb A, Danzer M, Gabriel C, et al. In vitro adipogenesis of adipose-derived stem cells in 3D fibrin matrix of low component concentration. J Tissue Eng Regen Med. 2012;6:434-442.
7. Agarwal B, Baur JA. Resveratrol and life extension. Ann N Y Acad Sci. 2011;1215:138-143.
8. Guarente L, Franklin H. Epstein Lecture: Sirtuins, aging, and medicine. N Engl J Med. 2011;364:2235-2244.
9. Smith DL Jr, Nagy TR, Allison DB. Calorie restriction: what recent results suggest for the future of ageing research. Eur J Clin Invest. 2010;40:440-450.
10. Picard F, Guarente L. Molecular links between aging and adipose tissue. Int J Obes. 2005;29(suppl 1):S36YS39.
11. Neuber F. Fettransplantation. Chir Kongr Verhandl Deutsche Gesellsch Chir. 1893;22:66.
12. Klinger M, Marazzi M, Vigo D, et al. Fat injection for cases of severe burn outcomes: a new perspective of scar remodeling and reduction. Aesthetic Plast Surg. 2008;32:465-469.
13. Coleman SR, Saboeiro AP. Fat grafting to the breast revisited: safety and efficacy. Plast Reconstr Surg. 2007;119:775-785; discussion 786-7.
14. Kanchwala SK, Glatt BS, Conant EF, et al. Autologous fat grafting to the reconstructed breast: the management of acquired contour deformities. Plast Reconstr Surg. 2009;124:409-418.
15. Coleman S. Facial recontouring with lipostructure. Clin Plast Surg. 1997;24: 347-367.
16. Del Vecchio DA, Bucky LP. Breast augmentation using preexpansion and autologous fat transplantation: a clinical radiographic study. Plast Reconstr Surg. 2011;127:2441-2450.
17. Yoshimura K, Sato K, Aoi N, et al. Cell-assisted lipotransfer for facial lipoatrophy: efficacy of clinical use of adipose-derived stem cells. Dermatol Surg. 2008;34:1178-1185.
18. Kuran I, Tumerdem B. A new simple method used to prepare fat for injection. Aesthetic Plast Surg. 2005;29:18-22; discussion 23.
19. Ramon Y, Shoshani O, Peled IJ, et al. Enhancing the take of injected adipose tissue by a simple method for concentrating fat cells. Plast Reconstr Surg. 2005;115:197-201; discussion 202-3.
20. Laharrague P, Casteilla L. The emergence of adipocytes. Endocr Dev. 2010; 19:1-30.
21. Bai X, Alt E. Myocardial regeneration potential of adipose tissue-derived stem cells. Biochem Biophys Res Commun. 2010;401:321-326.
22. Vaquero A, Sternglanz R, Reinberg D. NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs. Oncogene. 2007;26:5505-5520.
23. Lafontan M. Historical perspectives in fat cell biology: the fat cell as a model for the investigation of hormonal and metabolic pathways. Am J Physiol Cell Physiol. 2012;302:C327-C359.
24. Kennedy BK, Steffen KK, Kaeberlein M. Ruminations on dietary restriction and aging. Cell Mol Life Sci. 2007;64:1323-1328.
25. Han L, Ludovic Z, Kacey GM, et al. Adipogenic potential of adipose stem cell subpopulations, Plast Reconstr Surg. 2011;128:663-672.
26. GeneChip\Human Gene Chip 1.0ST by Affymetrix [cited 2012 January 12] Available from: www.affymetrix.com/browse/products.jsp?productId= 131453&categoryId=35676#1-1.
27. Kim D, Monaco E, Maki A, et al. Morphologic and transcriptomic comparison of adipose- and bone-marrow-derived porcine stem cells cultured in alginate hydrogels. Cell Tissue Res. 2010;341:359-370.
28. Conde J, Scotece M, Gómez R, et al. Adipokines: biofactors from white adipose tissue. A complex hub among inflammation, metabolism, and immunity. Biofactors. 2011;37:413-420.
29. Feser J, Tyler J. Chromatin structure as a mediator of aging. FEBS Lett. 2011; 585:2041-2048.