Monodisperse double-walled microspheres loaded with chitosan-p53 nanoparticles and doxorubicin for combined gene therapy and chemotherapy

Journal of Controlled Release

Volumn 163, Issue 2, 2012, Pages 130-135

  Xu, Qingxing ^a,b   Xia, Yujie ^a   Wang, Chi Hwa ^b   Pack, Daniel W ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Chitosan; Double walled microspheres; Doxorubicin; Gene therapy; p53; PLGA

Indexed keywords

CO-ENCAPSULATION; COMBINED MODALITY TREATMENT; DELIVERY SYSTEMS; DOUBLE-WALLED; DOXORUBICIN; ENCAPSULATION EFFICIENCY; MEAN DIAMETER; MONODISPERSE; P53; PLGA; POLY(D , L-LACTIC-CO-GLYCOLIC ACID); POLYLACTIC ACIDS; POROUS SURFACE; SHELL LAYERS; SHELL THICKNESS; SMOOTH SURFACE; TUMOR SUPPRESSOR PROTEINS;

CHEMOTHERAPY; CHITOSAN; COPOLYMERS; ENCAPSULATION; GENE ENCODING; GENE THERAPY; LACTIC ACID; NANOPARTICLES; SHELLS (STRUCTURES);

MICROSPHERES;

CHITOSAN; DOXORUBICIN; MICROSPHERE; NANOPARTICLE; PLASMID DNA; POLYGLACTIN; POLYLACTIC ACID; PROTEIN P53;

ARTICLE; CANCER CHEMOTHERAPY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; ENCAPSULATION; GENE THERAPY; IN VITRO STUDY; MOLECULAR WEIGHT; PARTICLE SIZE; POROSITY; PRIORITY JOURNAL;

ANTIBIOTICS, ANTINEOPLASTIC; CHITOSAN; DNA; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; GENETIC THERAPY; LACTIC ACID; MICROSPHERES; NANOPARTICLES; PLASMIDS; POLYGLYCOLIC ACID; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84866562443     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.08.032     Document Type: Article

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