Antibody-free, targeted mass-spectrometric approach for quantification of proteins at low picogram per milliliter levels in human plasma/serum

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 38, 2012, Pages 15395-15400

  Shi, Tujin ^a   Fillmore, Thomas L ^b   Sun, Xuefei ^a   Zhao, Rui ^b   Schepmoes, Athena A ^a   Hossain, Mahmud ^a   Xie, Fang ^a   Wu, Si ^b   Kim, Jong Seo ^a   Jones, Nathan ^a   Moore, Ronald J ^a   Paša Tolić, Ljiljana ^b   Kagan, Jacob ^c   Rodland, Karin D ^a   Liu, Tao ^a   Tang, Keqi ^a   Camp II, David G ^a   Smith, Richard D ^a,b   Qian, Wei Jun ^a  

^a PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^b PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Biomarker verification; Systems biology; Targeted proteomics

Indexed keywords

PROTEIN;

ARTICLE; BLOOD SAMPLING; FEMALE; HIGH PRESSURE HIGH RESOLUTION SEPARATION COUPLED WITH INTELLIGENT SELECTION AND MULTIPLEXING; HUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SELECTED REACTION MONITORING; SENSITIVITY ANALYSIS;

ANIMALS; ANTIBODIES; BIOLOGICAL MARKERS; BLOOD PROTEINS; CALIBRATION; CARBONIC ANHYDRASES; CATTLE; CHROMATOGRAPHY, LIQUID; FEMALE; HUMANS; MASS SPECTROMETRY; PROSTATE-SPECIFIC ANTIGEN; PROTEINS; PROTEOMICS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SYSTEMS BIOLOGY;

EID: 84866538934     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1204366109     Document Type: Article

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