메뉴 건너뛰기




Volumn 34, Issue 5, 2012, Pages 489-492

A puzzling case of increased serum clozapine levels in a patient with inflammation and infection

Author keywords

1 acid glycoprotein; antibiotics; clozapine; CYP1A2; drug interaction; infection

Indexed keywords

ACUTE PHASE PROTEIN; C REACTIVE PROTEIN; CIPROFLOXACIN; CLOZAPINE; CYTOCHROME P450; INTERLEUKIN 6; METRONIDAZOLE; OROSOMUCOID;

EID: 84866526910     PISSN: 01634356     EISSN: 15363694     Source Type: Journal    
DOI: 10.1097/FTD.0b013e3182666c62     Document Type: Article
Times cited : (38)

References (20)
  • 1
    • 70349684344 scopus 로고    scopus 로고
    • Does level of care, gender, age or choice of drug influence adherence to treatment with antipsychotics?
    • Castberg I, Westin AA, Spigset O. Does level of care, gender, age or choice of drug influence adherence to treatment with antipsychotics? J Clin Psychopharmacol. 2009;29:415-420.
    • (2009) J Clin Psychopharmacol. , vol.29 , pp. 415-420
    • Castberg, I.1    Westin, A.A.2    Spigset, O.3
  • 2
    • 0036377067 scopus 로고    scopus 로고
    • Bacterial pneumonia can increase serum concentration of clozapine
    • Raaska K, Raitasuo V, Arsttila M, et al. Bacterial pneumonia can increase serum concentration of clozapine. Eur J Clin Pharmacol. 2002;58:321-322.
    • (2002) Eur J Clin Pharmacol. , vol.58 , pp. 321-322
    • Raaska, K.1    Raitasuo, V.2    Arsttila, M.3
  • 3
    • 0141851847 scopus 로고    scopus 로고
    • Serious respiratory infections can increase clozapine levels and contribute to side effects: A case report
    • De Leon J, Diaz FJ. Serious respiratory infections can increase clozapine levels and contribute to side effects: a case report. Prog Neuropsycho- pharmacol Biol Psychiatry. 2003;27:1059-1063.
    • (2003) Prog Neuropsycho-pharmacol Biol Psychiatry. , vol.27 , pp. 1059-1063
    • De Leon, J.1    Diaz, F.J.2
  • 4
    • 15244362996 scopus 로고    scopus 로고
    • Toxic clozapine serum levels during acute urinary tract infection: A case report
    • Jecel J, Michel TM, Gutknecht L, et al. Toxic clozapine serum levels during acute urinary tract infection: a case report. Eur J Clin Pharmacol. 2005;60:909-910.
    • (2005) Eur J Clin Pharmacol. , vol.60 , pp. 909-910
    • Jecel, J.1    Michel, T.M.2    Gutknecht, L.3
  • 5
    • 0041882102 scopus 로고    scopus 로고
    • Toxic rise of clozapine plasma concentrations in relation to inflammation
    • Haack MJ, Bak ML, Beurskens R, et al. Toxic rise of clozapine plasma concentrations in relation to inflammation. Eur Neuropsychopharmacol. 2003;13:381-385.
    • (2003) Eur Neuropsychopharmacol. , vol.13 , pp. 381-385
    • Haack, M.J.1    Bak, M.L.2    Beurskens, R.3
  • 6
    • 4544247630 scopus 로고    scopus 로고
    • Respiratory infections rather that antibiotics may increase clozapine levels: A critical review of the literature
    • De Leon J. Respiratory infections rather that antibiotics may increase clozapine levels: a critical review of the literature. J Clin Psychiatry. 2004;65:1144-1145.
    • (2004) J Clin Psychiatry. , vol.65 , pp. 1144-1145
    • De Leon, J.1
  • 7
    • 0035660993 scopus 로고    scopus 로고
    • Effect of influenza vaccination on serum clozapine and its main metabolite concentrations in patients with schizophrenia
    • Raaska K, Raitasuo V, Neuvonen PJ. Effect of influenza vaccination on serum clozapine and its main metabolite concentrations in patients with schizophrenia. Eur J Clin Pharmacol. 2001;57:705-708.
    • (2001) Eur J Clin Pharmacol. , vol.57 , pp. 705-708
    • Raaska, K.1    Raitasuo, V.2    Neuvonen, P.J.3
  • 8
    • 33144485957 scopus 로고    scopus 로고
    • Regulation of drug-metabolising enzymes and transporters in inflammation
    • Aitken AE, Richardson TA, Morgan ET. Regulation of drug-metabolising enzymes and transporters in inflammation. Annu Rev Pharmacol Toxicol. 2006;46:123-149.
    • (2006) Annu Rev Pharmacol Toxicol. , vol.46 , pp. 123-149
    • Aitken, A.E.1    Richardson, T.A.2    Morgan, E.T.3
  • 9
    • 0034234716 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin-6 dependent
    • Siewert E, Bort R, Kluge R, et al. Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin-6 dependent. Hepatology. 2000;32:49-55.
    • (2000) Hepatology. , vol.32 , pp. 49-55
    • Siewert, E.1    Bort, R.2    Kluge, R.3
  • 10
    • 0031788790 scopus 로고    scopus 로고
    • Pharmacokinetics of clozapine and its metabolites in psychiatric patients: Plasma protein binding and renal clearance
    • Schaber G, Stevens I, Gaertner HJ, et al. Pharmacokinetics of clozapine and its metabolites in psychiatric patients: plasma protein binding and renal clearance. Br J Clin Pharmacol. 1998;46:453-459.
    • (1998) Br J Clin Pharmacol. , vol.46 , pp. 453-459
    • Schaber, G.1    Stevens, I.2    Gaertner, H.J.3
  • 11
    • 57349196359 scopus 로고    scopus 로고
    • Interindividual variation in relative CYP1A2/3A4 phenotype influences susceptibility of clozapine oxidation to cytochrome P450-specific inhibition in human hepatic micorsomes
    • Zhang WV, D'Esposito F, Edwards RJ, et al. Interindividual variation in relative CYP1A2/3A4 phenotype influences susceptibility of clozapine oxidation to cytochrome P450-specific inhibition in human hepatic micorsomes. Drug Metab Dispos. 2008;36:2547-2555.
    • (2008) Drug Metab Dispos. , vol.36 , pp. 2547-2555
    • Zhang, W.V.1    D'Esposito, F.2    Edwards, R.J.3
  • 12
    • 77954953005 scopus 로고    scopus 로고
    • Pregnane X receptor is required for interleukin-6 mediated downregulation of cytochrome P450 3A4 in human hepatocytes
    • Yang J, Hao C, Yang D, et al. Pregnane X receptor is required for interleukin-6 mediated downregulation of cytochrome P450 3A4 in human hepatocytes. Toxicol Lett. 2010;197:219-226.
    • (2010) Toxicol Lett. , vol.197 , pp. 219-226
    • Yang, J.1    Hao, C.2    Yang, D.3
  • 13
    • 79960606980 scopus 로고    scopus 로고
    • Effects of interleukin-6 (IL-6) and an anti-IL-6 monoclonal antibody on drug-metabolizing enzymes in human hepatocyte culture
    • Dickmann LJ, Patel SK, Rock DA, et al. Effects of interleukin-6 (IL-6) and an anti-IL-6 monoclonal antibody on drug-metabolizing enzymes in human hepatocyte culture. Drug Metab Dispos. 2011;39:1415-1422.
    • (2011) Drug Metab Dispos. , vol.39 , pp. 1415-1422
    • Dickmann, L.J.1    Patel, S.K.2    Rock, D.A.3
  • 14
    • 0036774272 scopus 로고    scopus 로고
    • Plasma levels of TNF-a and IL-6 are inversely related to cytochrome P450-dependent drug metabolism in patients with congestive heart failure
    • Frye RF, Schneider VM, Frye CS, et al. Plasma levels of TNF-a and IL-6 are inversely related to cytochrome P450-dependent drug metabolism in patients with congestive heart failure. J Card Fail. 2002;8:315-319.
    • (2002) J Card Fail. , vol.8 , pp. 315-319
    • Frye, R.F.1    Schneider, V.M.2    Frye, C.S.3
  • 15
    • 0030973317 scopus 로고    scopus 로고
    • Fluoroqionlone inhibition of clozapine metabolism
    • Markowitz JS, Gill HS, Devane CL, et al. Fluoroqionlone inhibition of clozapine metabolism. Am J Psychiatry. 1997;154:881.
    • (1997) Am J Psychiatry , vol.154 , pp. 881
    • Markowitz, J.S.1    Gill, H.S.2    Devane, C.L.3
  • 16
    • 34547785093 scopus 로고    scopus 로고
    • Interaction of clozapine and ciprofloxacin: A case report
    • Samhi RS, Puri R, Jones G. Interaction of clozapine and ciprofloxacin: a case report. Eur J Clin Pharmacol. 2007;63:895-896.
    • (2007) Eur J Clin Pharmacol. , vol.63 , pp. 895-896
    • Samhi, R.S.1    Puri, R.2    Jones, G.3
  • 17
    • 57449120964 scopus 로고    scopus 로고
    • Ciprofloxacin strongly inhibits clozapine metabolism
    • Brouwers EE, Söhne M, Kuipers S, et al. Ciprofloxacin strongly inhibits clozapine metabolism. Clin Drug Investig. 2009;29:59-63.
    • (2009) Clin Drug Investig. , vol.29 , pp. 59-63
    • Brouwers, E.E.1    Söhne, M.2    Kuipers, S.3
  • 18
    • 0033667335 scopus 로고    scopus 로고
    • Ciprofloxacin increases serum clozapine and N-desmethylclozapine: A study in patients with schizophrenia
    • Raaska K, Neuvonen PJ. Ciprofloxacin increases serum clozapine and N-desmethylclozapine: a study in patients with schizophrenia. Eur J Clin Pharmacol. 2000;56:585-589.
    • (2000) Eur J Clin Pharmacol. , vol.56 , pp. 585-589
    • Raaska, K.1    Neuvonen, P.J.2
  • 19
    • 0032711713 scopus 로고    scopus 로고
    • Clozapine serum concentrations are lower in smoking than in non-smoking schizophrenic patients
    • Seppälä NH, Leinonen EV, Lehtonen ML, et al. Clozapine serum concentrations are lower in smoking than in non-smoking schizophrenic patients. Pharmacol Toxicol. 1999; 85:244-246.
    • (1999) Pharmacol Toxicol. , vol.85 , pp. 244-246
    • Seppälä, N.H.1    Leinonen, E.V.2    Lehtonen, M.L.3
  • 20
    • 77950617446 scopus 로고    scopus 로고
    • Impact of tobacco smoking cessation of stable clozapine or olanzapine treatment
    • Lowe EJ, Ackman ML. Impact of tobacco smoking cessation of stable clozapine or olanzapine treatment. Ann Pharmacother. 2010;44:727-732.
    • (2010) Ann Pharmacother. , vol.44 , pp. 727-732
    • Lowe, E.J.1    Ackman, M.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.