Ciprofloxacin strongly inhibits clozapine metabolism: Two case reports

Clinical Drug Investigation

Volumn 29, Issue 1, 2009, Pages 59-63

  Brouwers, E E M ^a,c   Sohne M ^a   Kuipers, S ^a   Van Gorp, E C M ^a   Schellens, J H M ^a,b   Koks, C H W ^a   Beijnen, J H ^a,b   Huitema, A D R ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c SLOTERVAART HOSPITAL   (Netherlands)

Author keywords

Ciprofloxacin, drug interactions; Clozapine, drug interactions; Drug interactions; Rhabdomyolysis, drug induced; Schizophrenia

Indexed keywords

AMOXICILLIN; CIPROFLOXACIN; CITALOPRAM; CLONAZEPAM; CLOZAPINE; CYTOCHROME P450 1A2; CYTOCHROME P450 3A4; HYDROCHLOROTHIAZIDE; LORAZEPAM; VALPROIC ACID;

ADULT; ARTICLE; CASE REPORT; DELIRIUM; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG METABOLISM; ENZYME INHIBITION; HUMAN; MALE; PARANOID SCHIZOPHRENIA; PRIORITY JOURNAL; RHABDOMYOLYSIS; UROSEPSIS;

ANTI-INFECTIVE AGENTS, URINARY; ANTIPSYCHOTIC AGENTS; CIPROFLOXACIN; CLOZAPINE; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP3A; DRUG INTERACTIONS; HUMANS; MALE; MIDDLE AGED; PSYCHOTIC DISORDERS; SCHIZOPHRENIA;

EID: 57449120964     PISSN: 11732563     EISSN: None     Source Type: Journal    
DOI: 10.2165/0044011-200929010-00006     Document Type: Article

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