메뉴 건너뛰기




Volumn 7, Issue 9, 2012, Pages

Increased γ-H2A.X Intensity in Response to Chronic Medium-Dose-Rate γ-Ray Irradiation

Author keywords

[No Author keywords available]

Indexed keywords

DNA DEPENDENT PROTEIN KINASE; HISTONE H2AX;

EID: 84866521488     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0045320     Document Type: Article
Times cited : (6)

References (31)
  • 1
    • 0032508504 scopus 로고    scopus 로고
    • Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage
    • Banin S, Moyal L, Shieh S, Taya Y, Anderson CW, et al. (1998) Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage. Science 281: 1674-1677.
    • (1998) Science , vol.281 , pp. 1674-1677
    • Banin, S.1    Moyal, L.2    Shieh, S.3    Taya, Y.4    Anderson, C.W.5
  • 2
    • 0032508608 scopus 로고    scopus 로고
    • Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53
    • Canman CE, Lim DS, Cimprich KA, Taya Y, Tamai K, et al. (1998) Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53. Science 281: 1677-1679.
    • (1998) Science , vol.281 , pp. 1677-1679
    • Canman, C.E.1    Lim, D.S.2    Cimprich, K.A.3    Taya, Y.4    Tamai, K.5
  • 3
    • 36949026694 scopus 로고    scopus 로고
    • Activation and regulation of ATM kinase activity in response to DNA double-strand breaks
    • Lee JH, Paull TT, (2007) Activation and regulation of ATM kinase activity in response to DNA double-strand breaks. Oncogene 26: 7741-7748.
    • (2007) Oncogene , vol.26 , pp. 7741-7748
    • Lee, J.H.1    Paull, T.T.2
  • 4
    • 38049125555 scopus 로고    scopus 로고
    • The endless tale of non-homologous end-joining
    • Weterings E, Chen DJ, (2008) The endless tale of non-homologous end-joining. Cell Res. 18: 114-124.
    • (2008) Cell Res , vol.18 , pp. 114-124
    • Weterings, E.1    Chen, D.J.2
  • 5
    • 34249702972 scopus 로고    scopus 로고
    • Processing of DNA for Nonhomologous End-joining Is Controlled by Kinase Activity and XRCC4/Ligase IV
    • Budman J, Kim SA, (2007) Processing of DNA for Nonhomologous End-joining Is Controlled by Kinase Activity and XRCC4/Ligase IV. J Biol Chem. 282: 11950-11959.
    • (2007) J Biol Chem , vol.282 , pp. 11950-11959
    • Budman, J.1    Kim, S.A.2
  • 6
    • 38049115657 scopus 로고    scopus 로고
    • The Mechanism of Human Nonhomologous DNA End Joining
    • Lieber MR (2008) The Mechanism of Human Nonhomologous DNA End Joining. J Biol Chem. 283, 1-5.
    • (2008) J Biol Chem , vol.283 , pp. 1-5
    • Lieber, M.R.1
  • 8
    • 0042632901 scopus 로고    scopus 로고
    • Pathways of DNA Double-Strand Break Repair during the Mammalian Cell Cycle
    • Rothkamm K, Krüger I, Thompson LH, Löbrich M, (2003) Pathways of DNA Double-Strand Break Repair during the Mammalian Cell Cycle. Mol Cell Biol. 23: 5706-5715.
    • (2003) Mol Cell Biol , vol.23 , pp. 5706-5715
    • Rothkamm, K.1    Krüger, I.2    Thompson, L.H.3    Löbrich, M.4
  • 9
    • 0024395794 scopus 로고
    • H2A.X. a histone isoprotein with a conserved C-terminal sequence, is encoded by a novel mRNA with both DNA replication type and polyA 3' processing signals
    • Mannironi C, Bonner WM, Hatch CL, (1989) H2A.X. a histone isoprotein with a conserved C-terminal sequence, is encoded by a novel mRNA with both DNA replication type and polyA 3' processing signals. Nucleic Acids Res. 17: 9113-9126.
    • (1989) Nucleic Acids Res , vol.17 , pp. 9113-9126
    • Mannironi, C.1    Bonner, W.M.2    Hatch, C.L.3
  • 10
    • 0035834693 scopus 로고    scopus 로고
    • ATM phosphorylates histone H2A.X in response to DNA double-strand breaks
    • Burma S, Chen BP, Murphy M, Kurimasa A, Chen DJ, (2001) ATM phosphorylates histone H2A.X in response to DNA double-strand breaks. J Biol Chem. 276: 42462-42467.
    • (2001) J Biol Chem , vol.276 , pp. 42462-42467
    • Burma, S.1    Chen, B.P.2    Murphy, M.3    Kurimasa, A.4    Chen, D.J.5
  • 11
    • 1942538492 scopus 로고    scopus 로고
    • ATM and DNA-PK function redundantly to phosphorylate H2A.X after exposure to ionizing radiation
    • Stiff T, O'Driscoll M, Rief N, Iwabuchi K, Löbrich M, et al. (2004) ATM and DNA-PK function redundantly to phosphorylate H2A.X after exposure to ionizing radiation. Cancer Res. 64: 2390-2396.
    • (2004) Cancer Res , vol.64 , pp. 2390-2396
    • Stiff, T.1    O'Driscoll, M.2    Rief, N.3    Iwabuchi, K.4    Löbrich, M.5
  • 13
    • 0036789173 scopus 로고    scopus 로고
    • Quantitative detection of (125) IdU-induced DNA double-strand breaks with gamma-H2A.X antibody
    • Sedelnikova OA, Rogakou EP, Panyutin IG, Bonner WM, (2002) Quantitative detection of (125) IdU-induced DNA double-strand breaks with gamma-H2A.X antibody. Radiat Res. 158: 486-492.
    • (2002) Radiat Res , vol.158 , pp. 486-492
    • Sedelnikova, O.A.1    Rogakou, E.P.2    Panyutin, I.G.3    Bonner, W.M.4
  • 14
    • 0037884963 scopus 로고    scopus 로고
    • Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses
    • Rothkamm K, Löbrich M, (2003) Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses. Proc Natl Acad Sci U S A. 100: 5057-5062.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 5057-5062
    • Rothkamm, K.1    Löbrich, M.2
  • 15
    • 33644517203 scopus 로고    scopus 로고
    • DNA repair defect in AT cells and their hypersensitivity to low-dose-rate radiation
    • Nakamura H, Yasui Y, Saito N, Tachibana A, Komatsu K, et al. (2006) DNA repair defect in AT cells and their hypersensitivity to low-dose-rate radiation. Radiat Res. 165: 277-282.
    • (2006) Radiat Res , vol.165 , pp. 277-282
    • Nakamura, H.1    Yasui, Y.2    Saito, N.3    Tachibana, A.4    Komatsu, K.5
  • 16
    • 52249087113 scopus 로고    scopus 로고
    • Role of DNA double-strand break repair genes in cell proliferation under low dose-rate irradiation conditions
    • Tomita M, Morohoshi F, Matsumoto Y, Otsuka K, Sakai K, (2008) Role of DNA double-strand break repair genes in cell proliferation under low dose-rate irradiation conditions. J Radiat Res. 49: 557-564.
    • (2008) J Radiat Res , vol.49 , pp. 557-564
    • Tomita, M.1    Morohoshi, F.2    Matsumoto, Y.3    Otsuka, K.4    Sakai, K.5
  • 17
    • 12644253825 scopus 로고    scopus 로고
    • Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice
    • Araki R, Fujimori A, Hamatani K, Mita K, Saito T, et al. (1997) Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice. Proc Natl Acad Sci USA. 94: 2438-2443.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2438-2443
    • Araki, R.1    Fujimori, A.2    Hamatani, K.3    Mita, K.4    Saito, T.5
  • 18
    • 9644278078 scopus 로고    scopus 로고
    • Evasion of early cellular response mechanisms following low level radiation-induced DNA damage
    • Collis SJ, Schwaninger JM, Ntambi AJ, Keller TW, Nelson WG, et al. (2004) Evasion of early cellular response mechanisms following low level radiation-induced DNA damage. J. Biol. Chem. 279: 49624-49632.
    • (2004) J. Biol. Chem , vol.279 , pp. 49624-49632
    • Collis, S.J.1    Schwaninger, J.M.2    Ntambi, A.J.3    Keller, T.W.4    Nelson, W.G.5
  • 19
    • 77955145610 scopus 로고    scopus 로고
    • Participation of DNA-PKcs in DSB repair after exposure to high- and low-LET radiation
    • Anderson JA, Harper JV, Cucinotta FA, O'Neill P (2010) Participation of DNA-PKcs in DSB repair after exposure to high- and low-LET radiation. Radiat Res. 174,195-205.
    • (2010) Radiat Res , vol.174 , pp. 195-205
    • Anderson, J.A.1    Harper, J.V.2    Cucinotta, F.A.3    O'Neill, P.4
  • 20
    • 44949093617 scopus 로고    scopus 로고
    • A rapid flow cytometry test based on histone H2AX phosphorylation for the sensitive and specific diagnosis of ataxia telangiectasia
    • Porcedda P, Turinetto V, Brusco A, Cavalieri S, Lantelme E, et al. (2008) A rapid flow cytometry test based on histone H2AX phosphorylation for the sensitive and specific diagnosis of ataxia telangiectasia. Cytometry A. 73: 508-516.
    • (2008) Cytometry A , vol.73 , pp. 508-516
    • Porcedda, P.1    Turinetto, V.2    Brusco, A.3    Cavalieri, S.4    Lantelme, E.5
  • 21
    • 0029821651 scopus 로고    scopus 로고
    • Dual roles of ATM in the cellular response to radiation and in cell growth control
    • Xu Y, Baltimore D, (1996) Dual roles of ATM in the cellular response to radiation and in cell growth control. Genes Dev. 10: 2401-2410.
    • (1996) Genes Dev , vol.10 , pp. 2401-2410
    • Xu, Y.1    Baltimore, D.2
  • 22
    • 0035449355 scopus 로고    scopus 로고
    • Cell cycle checkpoint signaling through the ATM and ATR kinases
    • Abraham RT, (2001) Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev (15):: 2177-2196.
    • (2001) Genes Dev , Issue.15 , pp. 2177-2196
    • Abraham, R.T.1
  • 23
    • 0035930537 scopus 로고    scopus 로고
    • Histone H2A.X is phosphorylated in an ATR-dependent manner in response to replicational stress
    • Ward IM, Chen J, (2001) Histone H2A.X is phosphorylated in an ATR-dependent manner in response to replicational stress. J Biol Chem. 276: 47759-47762.
    • (2001) J Biol Chem , vol.276 , pp. 47759-47762
    • Ward, I.M.1    Chen, J.2
  • 24
    • 28444483130 scopus 로고    scopus 로고
    • gamma-H2A.X dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair
    • Chowdhury D, Keogh MC, Ishii H, Peterson CL, Buratowski S, et al. (2005) gamma-H2A.X dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair. Mol Cell. 20: 801-809.
    • (2005) Mol Cell , vol.20 , pp. 801-809
    • Chowdhury, D.1    Keogh, M.C.2    Ishii, H.3    Peterson, C.L.4    Buratowski, S.5
  • 25
    • 0141757504 scopus 로고    scopus 로고
    • p53 and radiation responses
    • Fei P, El-Deiry WS, (2003) p53 and radiation responses. Oncogene. 22: 5774-5783.
    • (2003) Oncogene , vol.22 , pp. 5774-5783
    • Fei, P.1    El-Deiry, W.S.2
  • 26
    • 79954498937 scopus 로고    scopus 로고
    • Activation of interferon-stimulated genes by gamma-ray irradiation independently of the ataxia telangiectasia mutated-p53 pathway
    • Sugihara T, Murano H, Nakamura M, Ichinohe K, Tanaka K, (2011) Activation of interferon-stimulated genes by gamma-ray irradiation independently of the ataxia telangiectasia mutated-p53 pathway. Mol Cancer Res. 9: 476-484.
    • (2011) Mol Cancer Res , vol.9 , pp. 476-484
    • Sugihara, T.1    Murano, H.2    Nakamura, M.3    Ichinohe, K.4    Tanaka, K.5
  • 27
    • 4644336002 scopus 로고    scopus 로고
    • Dose and dose-rate effects of low-dose ionizing radiation on activation of Trp53 in immortalized murine cells
    • Sugihara T, Magae J, Wadhwa R, Kaul SC, Kawakami Y, et al. (2004) Dose and dose-rate effects of low-dose ionizing radiation on activation of Trp53 in immortalized murine cells. Radiat Res. 162: 296-307.
    • (2004) Radiat Res , vol.162 , pp. 296-307
    • Sugihara, T.1    Magae, J.2    Wadhwa, R.3    Kaul, S.C.4    Kawakami, Y.5
  • 28
    • 44349158952 scopus 로고    scopus 로고
    • Inverse dose-rate-effects on the expressions of extra-cellular matrix-related genes in low-dose-rate gamma-ray irradiated murine cells
    • Sugihara T, Murano H, Tanaka K, Oghiso Y, (2008) Inverse dose-rate-effects on the expressions of extra-cellular matrix-related genes in low-dose-rate gamma-ray irradiated murine cells. J Radiat Res. 49: 231-240.
    • (2008) J Radiat Res , vol.49 , pp. 231-240
    • Sugihara, T.1    Murano, H.2    Tanaka, K.3    Oghiso, Y.4
  • 29
    • 13844294491 scopus 로고    scopus 로고
    • No induction of p53 phosphorylation and few focus formation of phosphorylated H2A.X suggest efficient repair of DNA damage during chronic low-dose-rate irradiation in human cells
    • Ishizaki K, Hayashi Y, Nakamura H, Yasui Y, Komatsu K, et al. (2004) No induction of p53 phosphorylation and few focus formation of phosphorylated H2A.X suggest efficient repair of DNA damage during chronic low-dose-rate irradiation in human cells. J Radiat Res. 45: 521-525.
    • (2004) J Radiat Res , vol.45 , pp. 521-525
    • Ishizaki, K.1    Hayashi, Y.2    Nakamura, H.3    Yasui, Y.4    Komatsu, K.5
  • 30
    • 79952182037 scopus 로고    scopus 로고
    • p53-Mediated gene activation in mice at high doses of chronic low-dose-rate γ radiation
    • Sugihara T, Murano H, Nakamura M, Ichinohe K, Tanaka K, (2011) p53-Mediated gene activation in mice at high doses of chronic low-dose-rate γ radiation. Radiat Res. 175: 328-335.
    • (2011) Radiat Res , vol.175 , pp. 328-335
    • Sugihara, T.1    Murano, H.2    Nakamura, M.3    Ichinohe, K.4    Tanaka, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.