Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality

Molecular and Cellular Biology

Volumn 27, Issue 19, 2007, Pages 6706-6717

  Ke, Yuehai ^a   Zhang, Eric E ^a,b   Hagihara, Kazuki ^a   Wu, Dongmei ^a   Pang, Yuhong ^a   Klein, Rüdiger ^c   Curran, Tom ^d   Ranscht, Barbara ^a   Feng, Gen Sheng ^a,b  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

^d CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CRE RECOMBINASE; MITOGEN ACTIVATED PROTEIN KINASE; NESTIN; PROTEIN BMI1; PROTEIN TYROSINE PHOSPHATASE SHP 2; REGULATOR PROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN VENTRICLE; CELL DIFFERENTIATION; CELL FATE; CELL PROLIFERATION; CELL RENEWAL; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; GENE DELETION; GLIA CELL; LETHALITY; MALE; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; ASTROCYTES; BRAIN; CELL DIFFERENTIATION; CELL PROLIFERATION; FEMALE; IN SITU HYBRIDIZATION; MALE; MICE; MICE, TRANSGENIC; NEURONS; NUCLEAR PROTEINS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; PROTO-ONCOGENE PROTEINS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 34748824069     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01225-07     Document Type: Article

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