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Volumn 515, Issue , 2012, Pages 359-377

Type III polyketide synthases in microorganisms

Author keywords

Enzyme assay; Genome mining; Heterologous expression; Microorganism; Polyketide; Type III polyketide synthase

Indexed keywords

POLYKETIDE SYNTHASE; RECOMBINANT TYPE III POLYKETIDE SYNTHASE; UNCLASSIFIED DRUG;

EID: 84866513691     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/B978-0-12-394290-6.00017-3     Document Type: Chapter
Times cited : (42)

References (44)
  • 1
    • 77953053139 scopus 로고    scopus 로고
    • Structure and function of the chalcone synthase superfamily of plant type III polyketide synthases
    • I. Abe, and H. Morita Structure and function of the chalcone synthase superfamily of plant type III polyketide synthases Natural Product Reports 27 2010 809 838
    • (2010) Natural Product Reports , vol.27 , pp. 809-838
    • Abe, I.1    Morita, H.2
  • 3
    • 80053372186 scopus 로고    scopus 로고
    • Physiological role of germicidins in spore germination and hyphal elongation in Streptomyces coelicolor A3(2)
    • Y. Aoki, D. Matsumoto, H. Kawaide, and M. Natsume Physiological role of germicidins in spore germination and hyphal elongation in Streptomyces coelicolor A3(2) The Journal of Antibiotics 64 2011 607 611
    • (2011) The Journal of Antibiotics , vol.64 , pp. 607-611
    • Aoki, Y.1    Matsumoto, D.2    Kawaide, H.3    Natsume, M.4
  • 4
    • 33747598945 scopus 로고    scopus 로고
    • Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase
    • DOI 10.1038/nchembio811, PII NCHEMBIO811
    • M.B. Austin, T. Saito, M.E. Bowman, S. Haydock, A. Kato, and B.S. Moore Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase Nature Chemical Biology 2 2006 494 502 (Pubitemid 44266312)
    • (2006) Nature Chemical Biology , vol.2 , Issue.9 , pp. 494-502
    • Austin, M.B.1    Saito, T.2    Bowman, M.E.3    Haydock, S.4    Kato, A.5    Moore, B.S.6    Kay, R.R.7    Noel, J.P.8
  • 5
    • 79551546286 scopus 로고    scopus 로고
    • Characterization of the biosynthesis gene cluster for alkyl-O-dihydrogeranyl-methoxyhydroquinones in Actinoplanes missouriensis
    • T. Awakawa, N. Fujita, M. Hayakawa, Y. Ohnishi, and S. Horinouchi Characterization of the biosynthesis gene cluster for alkyl-O-dihydrogeranyl- methoxyhydroquinones in Actinoplanes missouriensis Chembiochem 12 2011 39 48
    • (2011) Chembiochem , vol.12 , pp. 39-48
    • Awakawa, T.1    Fujita, N.2    Hayakawa, M.3    Ohnishi, Y.4    Horinouchi, S.5
  • 6
    • 0032912472 scopus 로고    scopus 로고
    • Identification and characterization of a gene cluster for synthesis of the polyketide antibiotic 2,4-diacetylphloroglucinol from pseudomonas fluorescens q2-87
    • M.G. Bangera, and L.S. Thomashow Identification and characterization of a gene cluster for synthesis of the polyketide antibiotic 2,4- diacetylphloroglucinol from Pseudomonas fluorescens Q2-87 Journal of Bacteriology 181 1999 3155 3163 (Pubitemid 29236921)
    • (1999) Journal of Bacteriology , vol.181 , Issue.10 , pp. 3155-3163
    • Bangera, M.G.1    Thomashow, L.S.2
  • 7
    • 0019762564 scopus 로고
    • Synthesis of long-chain fatty acyl-CoA thioesters using N-hydroxysuccinimide esters
    • M. Blecher Synthesis of long-chain fatty acyl-CoA thioesters using N-hydroxysuccinimide esters Methods in Enzymology 72 1981 404 408
    • (1981) Methods in Enzymology , vol.72 , pp. 404-408
    • Blecher, M.1
  • 8
    • 0035910072 scopus 로고    scopus 로고
    • Glycopeptide antibiotic biosynthesis: Enzymatic assembly of the dedicated amino acid monomer (S)-3,5-dihydroxyphenylglycine
    • DOI 10.1073/pnas.221582098
    • H. Chen, C.C. Tseng, B.K. Hubbard, and C.T. Walsh Glycopeptide antibiotic biosynthesis: Enzymatic assembly of the dedicated amino acid monomer (S)-3,5-dihydroxyphenylglycine Proceedings of the National Academy of Sciences of the United States of America 98 2001 14901 14906 (Pubitemid 34013942)
    • (2001) Proceedings of the National Academy of Sciences of the United States of America , vol.98 , Issue.26 , pp. 14901-14906
    • Chen, H.1    Tseng, C.C.2    Hubbard, B.K.3    Walsh, C.T.4
  • 9
    • 0036015638 scopus 로고    scopus 로고
    • Identification and cloning of a type III polyketide synthase required for diffusible pigment biosynthesis in Saccharopolyspora erythraea
    • DOI 10.1046/j.1365-2958.2002.02975.x
    • J. Cortés, J. Velasco, G. Foster, A.P. Blackaby, B.A. Rudd, and B. Wilkinson Identification and cloning of a type III polyketide synthase required for diffusible pigment biosynthesis in Saccharopolyspora erythraea Molecular Microbiology 44 2002 1213 1224 (Pubitemid 34595754)
    • (2002) Molecular Microbiology , vol.44 , Issue.5 , pp. 1213-1224
    • Cortes, J.1    Velasco, J.2    Foster, G.3    Blackaby, A.P.4    Rudd, B.A.M.5    Wilkinson, B.6
  • 10
    • 34347255733 scopus 로고    scopus 로고
    • Pentaketide resorcylic acid synthesis by type III polyketide synthase from Neurospora crassa
    • DOI 10.1074/jbc.M701239200
    • N. Funa, T. Awakawa, and S. Horinouchi Pentaketide resorcylic acid synthesis by type III polyketide synthase from Neurospora crassa The Journal of Biological Chemistry 282 2007 14476 14481 (Pubitemid 47100443)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.19 , pp. 14476-14481
    • Funa, N.1    Awakawa, T.2    Horinouchi, S.3
  • 11
    • 28044436696 scopus 로고    scopus 로고
    • Biosynthesis of hexahydroxyperylenequinone melanin via oxidative aryl coupling by cytochrome P-450 in Streptomyces griseus
    • DOI 10.1128/JB.187.23.8149-8155.2005
    • N. Funa, M. Funabashi, Y. Ohnishi, and S. Horinouchi Biosynthesis of hexahydroxyperylenequinone melanin via oxidative aryl coupling by cytochrome P-450 in Streptomyces griseus Journal of Bacteriology 187 2005 8149 8155 (Pubitemid 41691707)
    • (2005) Journal of Bacteriology , vol.187 , Issue.23 , pp. 8149-8155
    • Funa, N.1    Funabashi, M.2    Ohnishi, Y.3    Horinouchi, S.4
  • 12
    • 17644389609 scopus 로고    scopus 로고
    • A novel quinone-forming monooxygenase family involved in modification of aromatic polyketides
    • DOI 10.1074/jbc.M500190200
    • N. Funa, M. Funabashi, E. Yoshimura, and S. Horinouchi A novel quinone-forming monooxygenase family involved in modification of aromatic polyketides The Journal of Biological Chemistry 280 2005 14514 14523 (Pubitemid 40562793)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.15 , pp. 14514-14523
    • Funa, N.1    Funabashi, M.2    Yoshimura, E.3    Horinouchi, S.4
  • 13
    • 0037085447 scopus 로고    scopus 로고
    • Properties and substrate specificity of RppA, a chalcone synthase-related polyketide synthase in Streptomyces griseus
    • DOI 10.1074/jbc.M110357200
    • N. Funa, Y. Ohnishi, Y. Ebizuka, and S. Horinouchi Properties and substrate specificity of RppA, a chalcone synthase-related polyketide synthase in Streptomyces griseus The Journal of Biological Chemistry 277 2002 4628 4635 (Pubitemid 34968491)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.7 , pp. 4628-4635
    • Funa, N.1    Ohnishi, Y.2    Ebizuka, Y.3    Horinouchi, S.4
  • 14
    • 0036844888 scopus 로고    scopus 로고
    • Alteration of reaction and substrate specificity of a bacterial type III polyketide synthase by site-directed mutagenesis
    • DOI 10.1042/BJ20020953
    • N. Funa, Y. Ohnishi, Y. Ebizuka, and S. Horinouchi Alteration of reaction and substrate specificity of a bacterial type III polyketide synthase by site-directed mutagenesis The Biochemical Journal 367 2002 781 789 (Pubitemid 35305717)
    • (2002) Biochemical Journal , vol.367 , Issue.3 , pp. 781-789
    • Funa, N.1    Ohnishi, Y.2    Ebizuka, Y.3    Horinouchi, S.4
  • 15
    • 0033606986 scopus 로고    scopus 로고
    • A new pathway for polyketide synthesis in microorganisms
    • DOI 10.1038/23748
    • N. Funa, Y. Ohnishi, I. Fujii, M. Shibuya, Y. Ebizuka, and S. Horinouchi A new pathway for polyketide synthesis in microorganisms Nature 400 1999 897 899 (Pubitemid 29406729)
    • (1999) Nature , vol.400 , Issue.6747 , pp. 897-899
    • Funa, N.1    Ohnishi, Y.2    Fujli, I.3    Shibuya, M.4    Ebizuka, Y.5    Horinouchi, S.6
  • 17
    • 46649102699 scopus 로고    scopus 로고
    • Phenolic lipids synthesized by type III polyketide synthase confer penicillin resistance on Streptomyces griseus
    • M. Funabashi, N. Funa, and S. Horinouchi Phenolic lipids synthesized by type III polyketide synthase confer penicillin resistance on Streptomyces griseus The Journal of Biological Chemistry 283 2008 13983 13991
    • (2008) The Journal of Biological Chemistry , vol.283 , pp. 13983-13991
    • Funabashi, M.1    Funa, N.2    Horinouchi, S.3
  • 18
    • 45549096981 scopus 로고    scopus 로고
    • Dissecting the functional role of polyketide synthases in Dictyostelium discoideum: Biosynthesis of the differentiation regulating factor 4-methyl-5-pentylbenzene-1,3-diol
    • R. Ghosh, A. Chhabra, P.A. Phatale, S.K. Samrat, J. Sharma, and A. Gosain Dissecting the functional role of polyketide synthases in Dictyostelium discoideum: Biosynthesis of the differentiation regulating factor 4-methyl-5-pentylbenzene-1,3-diol The Journal of Biological Chemistry 283 2008 11348 11354
    • (2008) The Journal of Biological Chemistry , vol.283 , pp. 11348-11354
    • Ghosh, R.1    Chhabra, A.2    Phatale, P.A.3    Samrat, S.K.4    Sharma, J.5    Gosain, A.6
  • 19
    • 33644552441 scopus 로고    scopus 로고
    • Bacterial type III polyketide synthases: Phylogenetic analysis and potential for the production of novel secondary metabolites by heterologous expression in pseudomonads
    • DOI 10.1007/s00203-005-0059-3
    • F. Gross, N. Luniak, O. Perlova, N. Gaitatzis, H. Jenke-Kodama, and K. Gerth Bacterial type III polyketide synthases: Phylogenetic analysis and potential for the production of novel secondary metabolites by heterologous expression in pseudomonads Archives of Microbiology 185 2006 28 38 (Pubitemid 43293202)
    • (2006) Archives of Microbiology , vol.185 , Issue.1 , pp. 28-38
    • Gross, F.1    Luniak, N.2    Perlova, O.3    Gaitatzis, N.4    Jenke-Kodama, H.5    Gerth, K.6    Gottschalk, D.7    Dittmann, E.8    Muller, R.9
  • 20
    • 34447521692 scopus 로고    scopus 로고
    • Substrate profile analysis and ACP-mediated acyl transfer in Streptomyces coelicolor type III polyketide synthases
    • DOI 10.1002/cbic.200700026
    • S. Grüschow, T.J. Buchholz, W. Seufert, J.S. Dordick, and D.H. Sherman Substrate profile analysis and ACP-mediated acyl transfer in Streptomyces coelicolor type III polyketide synthases Chembiochem 8 2007 863 868 (Pubitemid 47194833)
    • (2007) ChemBioChem , vol.8 , Issue.8 , pp. 863-868
    • Gruschow, S.1    Buchholz, T.J.2    Seufert, W.3    Dordick, J.S.4    Sherman, D.H.5
  • 21
    • 33845468380 scopus 로고    scopus 로고
    • A gene cluster for prenylated naphthoquinone and prenylated phenazine biosynthesis in Streptomyces cinnamonensis DSM 1042
    • DOI 10.1002/cbic.200600338
    • Y. Haagen, K. Glück, K. Fay, B. Kammerer, B. Gust, and L. Heide A gene cluster for prenylated naphthoquinone and prenylated phenazine biosynthesis in Streptomyces cinnamonensis DSM 1042 Chembiochem 7 2006 2016 2027 (Pubitemid 44893540)
    • (2006) ChemBioChem , vol.7 , Issue.12 , pp. 2016-2027
    • Haaqen, Y.1    Gluck, K.2    Fay, K.3    Kammerer, B.4    Gust, B.5    Heide, L.6
  • 22
    • 80052779786 scopus 로고    scopus 로고
    • Fatty acyl-AMP ligase involvement in the production of alkylresorcylic acid by a Myxococcus xanthus type III polyketide synthase
    • T. Hayashi, Y. Kitamura, N. Funa, Y. Ohnishi, and S. Horinouchi Fatty acyl-AMP ligase involvement in the production of alkylresorcylic acid by a Myxococcus xanthus type III polyketide synthase Chembiochem 12 2011 2166 2176
    • (2011) Chembiochem , vol.12 , pp. 2166-2176
    • Hayashi, T.1    Kitamura, Y.2    Funa, N.3    Ohnishi, Y.4    Horinouchi, S.5
  • 24
    • 0141483081 scopus 로고    scopus 로고
    • Expression and characterization of the type III polyketide synthase 1,3,6,8-tetrahydroxynaphthalene synthase from Streptomyces coelicolor A3(2)
    • DOI 10.1007/s10295-003-0075-8
    • M. Izumikawa, P.R. Shipley, J.N. Hopke, T. O'Hare, L. Xiang, and J.P. Noel Expression and characterization of the type III polyketide synthase 1,3,6,8-tetrahydroxynaphthalene synthase from Streptomyces coelicolor A3(2) Journal of Industrial Microbiology & Biotechnology 30 2003 510 515 (Pubitemid 37214972)
    • (2003) Journal of Industrial Microbiology and Biotechnology , vol.30 , Issue.8 , pp. 510-515
    • Izumikawa, M.1    Shipley, P.R.2    Hopke, J.N.3    O'Hare, T.4    Xiang, L.5    Noel, J.P.6    Moore, B.S.7
  • 26
    • 32444437181 scopus 로고    scopus 로고
    • Biosynthesis of a natural polyketide-isoprenoid hybrid compound, furaquinocin A: Identification and heterologous expression of the gene cluster
    • DOI 10.1128/JB.188.4.1236-1244.2006
    • T. Kawasaki, Y. Hayashi, T. Kuzuyama, K. Furihata, N. Itoh, and H. Seto Biosynthesis of a natural polyketide-isoprenoid hybrid compound, furaquinocin A: Identification and heterologous expression of the gene cluster Journal of Bacteriology 188 2006 1236 1244 (Pubitemid 43228655)
    • (2006) Journal of Bacteriology , vol.188 , Issue.4 , pp. 1236-1244
    • Kawasaki, T.1    Hayashi, Y.2    Kuzuyama, T.3    Furihata, K.4    Itoh, N.5    Seto, H.6    Dairi, T.7
  • 28
    • 78650063484 scopus 로고    scopus 로고
    • Functional characterization of the promiscuous prenyltransferase responsible for furaquinocin biosynthesis: Identification of a physiological polyketide substrate and its prenylated reaction products
    • T. Kumano, T. Tomita, M. Nishiyama, and T. Kuzuyama Functional characterization of the promiscuous prenyltransferase responsible for furaquinocin biosynthesis: Identification of a physiological polyketide substrate and its prenylated reaction products The Journal of Biological Chemistry 285 2010 39663 39671
    • (2010) The Journal of Biological Chemistry , vol.285 , pp. 39663-39671
    • Kumano, T.1    Tomita, T.2    Nishiyama, M.3    Kuzuyama, T.4
  • 29
    • 20544457539 scopus 로고    scopus 로고
    • Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products
    • DOI 10.1038/nature03668
    • T. Kuzuyama, J.P. Noel, and S.B. Richard Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products Nature 435 2005 983 987 (Pubitemid 40896327)
    • (2005) Nature , vol.435 , Issue.7044 , pp. 983-987
    • Kuzuyama, T.1    Noel, J.P.2    Richard, S.B.3
  • 30
    • 34250325921 scopus 로고    scopus 로고
    • Molecular analysis of the role of tyrosine 224 in the active site of Streptomyces coelicolor RppA, a bacterial type III polyketide synthase
    • DOI 10.1074/jbc.M700393200
    • S. Li, S. Grüschow, J.S. Dordick, and D.H. Sherman Molecular analysis of the role of tyrosine 224 in the active site of Streptomyces coelicolor RppA, a bacterial type III polyketide synthase The Journal of Biological Chemistry 282 2007 12765 12772 (Pubitemid 47100598)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.17 , pp. 12765-12772
    • Li, S.1    Gruschow, S.2    Dordick, J.S.3    Sherman, D.H.4
  • 31
    • 38949095007 scopus 로고    scopus 로고
    • Direct transfer of starter substrates from type I fatty acid synthase to type III polyketide synthases in phenolic lipid synthesis
    • DOI 10.1073/pnas.0709819105
    • A. Miyanaga, N. Funa, T. Awakawa, and S. Horinouchi Direct transfer of starter substrates from type I fatty acid synthase to type III polyketide synthases in phenolic lipid synthesis Proceedings of the National Academy of Sciences of the United States of America 105 2008 871 876 (Pubitemid 351282048)
    • (2008) Proceedings of the National Academy of Sciences of the United States of America , vol.105 , Issue.3 , pp. 871-876
    • Miyanaga, A.1    Funa, N.2    Awakawa, T.3    Horinouchi, S.4
  • 32
    • 0038015176 scopus 로고    scopus 로고
    • A continuous coupled enzyme assay for bacterial malonyl-CoA:acyl carrier protein transacylase (FabD)
    • DOI 10.1016/S0003-2697(03)00327-0
    • J. Molnos, R. Gardiner, G.E. Dale, and R. Lange A continuous coupled enzyme assay for bacterial malonyl-CoA: Acyl carrier protein transacylase (FabD) Analytical Biochemistry 319 2003 171 176 (Pubitemid 36802155)
    • (2003) Analytical Biochemistry , vol.319 , Issue.1 , pp. 171-176
    • Molnos, J.1    Gardiner, R.2    Dale, G.E.3    Lange, R.4
  • 34
    • 84857973395 scopus 로고    scopus 로고
    • The O-methyltransferase SrsB catalyzes the decarboxylative methylation of alkylresorcylic acid during phenolic lipid biosynthesis by Streptomyces griseus
    • C. Nakano, N. Funa, Y. Ohnishi, and S. Horinouchi The O-methyltransferase SrsB catalyzes the decarboxylative methylation of alkylresorcylic acid during phenolic lipid biosynthesis by Streptomyces griseus Journal of Bacteriology 194 2012 1544 1551
    • (2012) Journal of Bacteriology , vol.194 , pp. 1544-1551
    • Nakano, C.1    Funa, N.2    Ohnishi, Y.3    Horinouchi, S.4
  • 35
    • 67749086002 scopus 로고    scopus 로고
    • Biosynthesis of aliphatic polyketides by type III polyketide synthase and methyltransferase in Bacillus subtilis
    • C. Nakano, H. Ozawa, G. Akanuma, N. Funa, and S. Horinouchi Biosynthesis of aliphatic polyketides by type III polyketide synthase and methyltransferase in Bacillus subtilis Journal of Bacteriology 191 2009 4916 4923
    • (2009) Journal of Bacteriology , vol.191 , pp. 4916-4923
    • Nakano, C.1    Ozawa, H.2    Akanuma, G.3    Funa, N.4    Horinouchi, S.5
  • 36
    • 77950547477 scopus 로고    scopus 로고
    • A flavin-dependent halogenase catalyzes the chlorination step in the biosynthesis of Dictyostelium differentiation-inducing factor 1
    • C.S. Neumann, C.T. Walsh, and R.R. Kay A flavin-dependent halogenase catalyzes the chlorination step in the biosynthesis of Dictyostelium differentiation-inducing factor 1 Proceedings of the National Academy of Sciences of the United States of America 107 2010 5798 5803
    • (2010) Proceedings of the National Academy of Sciences of the United States of America , vol.107 , pp. 5798-5803
    • Neumann, C.S.1    Walsh, C.T.2    Kay, R.R.3
  • 37
    • 7644240394 scopus 로고    scopus 로고
    • Probing biosynthesis of plant polyketides with synthetic N-acetylcysteamine thioesters
    • DOI 10.1016/j.bbrc.2004.10.057, PII S0006291X04023794
    • S. Oguro, T. Akashi, S. Ayabe, H. Noguchi, and I. Abe Probing biosynthesis of plant polyketides with synthetic N-acetylcysteamine thioesters Biochemical and Biophysical Research Communications 325 2004 561 567 (Pubitemid 39458031)
    • (2004) Biochemical and Biophysical Research Communications , vol.325 , Issue.2 , pp. 561-567
    • Oguro, S.1    Akashi, T.2    Ayabe, S.-I.3    Noguchi, H.4    Abe, I.5
  • 38
    • 0035914455 scopus 로고    scopus 로고
    • A polyketide synthase in glycopeptide biosynthesis: The biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine
    • V. Pfeifer, G.J. Nicholson, J. Ries, J. Recktenwald, A.B. Schefer, and R.M. Shawky A polyketide synthase in glycopeptide biosynthesis: The biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine The Journal of Biological Chemistry 276 2001 38370 38377
    • (2001) The Journal of Biological Chemistry , vol.276 , pp. 38370-38377
    • Pfeifer, V.1    Nicholson, G.J.2    Ries, J.3    Recktenwald, J.4    Schefer, A.B.5    Shawky, R.M.6
  • 40
    • 77953139150 scopus 로고    scopus 로고
    • Identification of csypyrone B1 as the novel product of Aspergillus oryzae type III polyketide synthase CsyB
    • Y. Seshime, P.R. Juvvadi, K. Kitamoto, Y. Ebizuka, and I. Fujii Identification of csypyrone B1 as the novel product of Aspergillus oryzae type III polyketide synthase CsyB Bioorganic & Medicinal Chemistry 18 2010 4542 4546
    • (2010) Bioorganic & Medicinal Chemistry , vol.18 , pp. 4542-4546
    • Seshime, Y.1    Juvvadi, P.R.2    Kitamoto, K.3    Ebizuka, Y.4    Fujii, I.5
  • 42
    • 33845212858 scopus 로고    scopus 로고
    • Type III polyketide synthase ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining
    • DOI 10.1021/ja065247w
    • L. Song, F. Barona-Gomez, C. Corre, L. Xiang, D.W. Udwary, and M.B. Austin Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining Journal of the American Chemical Society 128 2006 14754 14755 (Pubitemid 44851585)
    • (2006) Journal of the American Chemical Society , vol.128 , Issue.46 , pp. 14754-14755
    • Song, L.1    Barona-Gomez, F.2    Corre, C.3    Xiang, L.4    Udwary, D.W.5    Austin, M.B.6    Noel, J.P.7    Moore, B.S.8    Challis, G.L.9
  • 43
    • 0028867394 scopus 로고
    • Construction of thiostrepton-inducible, high-copy-number expression vectors for use in Streptomyces spp
    • E. Takano, J. White, C.J. Thompson, and M.J. Bibb Construction of thiostrepton-inducible, high-copy-number expression vectors for use in Streptomyces spp Gene 166 1995 133 137
    • (1995) Gene , vol.166 , pp. 133-137
    • Takano, E.1    White, J.2    Thompson, C.J.3    Bibb, M.J.4
  • 44
    • 59449083487 scopus 로고    scopus 로고
    • A type I/type III polyketide synthase hybrid biosynthetic pathway for the structurally unique ansa compound kendomycin
    • S.C. Wenzel, H.B. Bode, I. Kochems, and R. Müller A type I/type III polyketide synthase hybrid biosynthetic pathway for the structurally unique ansa compound kendomycin Chembiochem 9 2008 2711 2721
    • (2008) Chembiochem , vol.9 , pp. 2711-2721
    • Wenzel, S.C.1    Bode, H.B.2    Kochems, I.3    Müller, R.4


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