메뉴 건너뛰기




Volumn 18, Issue 6, 2012, Pages 846-855

The role of MicroRNAs miR-200b and miR-200c in TLR4 signaling and NF-κB activation

Author keywords

gene expression; Macrophage; microRNAs; pro inflammatory response; Toll like receptor

Indexed keywords

CXCL9 CHEMOKINE; CYTOKINE; ENDOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 6; MICRORNA 200B; MICRORNA 200C; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TOLL LIKE RECEPTOR AGONIST; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

EID: 84866509566     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425912443903     Document Type: Article
Times cited : (130)

References (52)
  • 3
    • 38549157506 scopus 로고    scopus 로고
    • Molecular biology: The expanding world of small RNAs
    • Grosshans H, Filipowicz W. Molecular biology: the expanding world of small RNAs. Nature. 2008 ; 451: 414-416
    • (2008) Nature , vol.451 , pp. 414-416
    • Grosshans, H.1    Filipowicz, W.2
  • 5
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T. Identification of novel genes coding for small expressed RNAs. Science. 2001 ; 294: 853-858
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 6
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 1993 ; 75: 843-854
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 7
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 2005 ; 120: 15-20
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 8
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature. 2005 ; 433: 769-773
    • (2005) Nature , vol.433 , pp. 769-773
    • Lim, L.P.1    Lau, N.C.2    Garrett-Engele, P.3    Grimson, A.4    Schelter, J.M.5    Castle, J.6
  • 10
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C
    • Wightman B, Ha I, Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell. 1993 ; 75: 855-862
    • (1993) Elegans. Cell , vol.75 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 11
    • 38949195105 scopus 로고    scopus 로고
    • Messenger RNA regulation: To translate or to degrade
    • Shyu AB, Wilkinson MF, van Hoof A. Messenger RNA regulation: to translate or to degrade. EMBO J. 2008 ; 27: 471-481
    • (2008) EMBO J , vol.27 , pp. 471-481
    • Shyu, A.B.1    Wilkinson, M.F.2    Van Hoof, A.3
  • 13
    • 67349115688 scopus 로고    scopus 로고
    • MicroRNAs: Novel regulators of immunity
    • Carissimi C, Fulci V, Macino G. MicroRNAs: novel regulators of immunity. Autoimmun Rev. 2009 ; 8: 520-524
    • (2009) Autoimmun Rev , vol.8 , pp. 520-524
    • Carissimi, C.1    Fulci, V.2    MacIno, G.3
  • 14
    • 51349163431 scopus 로고    scopus 로고
    • MicroRNAs in the immune response
    • Pedersen I, David M. MicroRNAs in the immune response. Cytokine. 2008 ; 43: 391-394
    • (2008) Cytokine , vol.43 , pp. 391-394
    • Pedersen, I.1    David, M.2
  • 15
    • 34249810892 scopus 로고    scopus 로고
    • Argonaute proteins: Mediators of RNA silencing
    • Peters L, Meister G. Argonaute proteins: mediators of RNA silencing. Mol Cell. 2007 ; 26: 611-623
    • (2007) Mol Cell , vol.26 , pp. 611-623
    • Peters, L.1    Meister, G.2
  • 16
    • 77955644289 scopus 로고    scopus 로고
    • Mammalian microRNAs predominantly act to decrease target mRNA levels
    • Guo H, Ingolia NT, Weissman JS, Bartel DP. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature. 2010 ; 466: 835-840
    • (2010) Nature , vol.466 , pp. 835-840
    • Guo, H.1    Ingolia, N.T.2    Weissman, J.S.3    Bartel, D.P.4
  • 18
    • 79952779639 scopus 로고    scopus 로고
    • MicroRNA, a new paradigm for understanding immunoregulation, inflammation, and autoimmune diseases
    • Dai R, Ahmed SA. MicroRNA, a new paradigm for understanding immunoregulation, inflammation, and autoimmune diseases. Transl Res. 2011 ; 157: 163-179
    • (2011) Transl Res , vol.157 , pp. 163-179
    • Dai, R.1    Ahmed, S.A.2
  • 19
    • 0024955886 scopus 로고
    • Approaching the asymptote? Evolution and revolution in immunology
    • Janeway CA. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb Symp Quant Biol. 1989 ; 54: 1-13
    • (1989) Cold Spring Harb Symp Quant Biol , vol.54 , pp. 1-13
    • Janeway, C.A.1
  • 20
    • 75449093273 scopus 로고    scopus 로고
    • TIR-containing adaptors in Toll-like receptor signalling
    • Jenkins KA, Mansell A. TIR-containing adaptors in Toll-like receptor signalling. Cytokine. 2010 ; 49: 237-244
    • (2010) Cytokine , vol.49 , pp. 237-244
    • Jenkins, K.A.1    Mansell, A.2
  • 21
    • 0032191163 scopus 로고    scopus 로고
    • Innate immune recognition and control of adaptive immune responses
    • Medzhitov R, Janeway CA. Innate immune recognition and control of adaptive immune responses. Semin Immunol. 1998 ; 10: 351-353
    • (1998) Semin Immunol , vol.10 , pp. 351-353
    • Medzhitov, R.1    Janeway, C.A.2
  • 22
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-kappaB signaling
    • Hayden MS, Ghosh S. Shared principles in NF-kappaB signaling. Cell. 2008 ; 132: 344-362
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 23
    • 79952498248 scopus 로고    scopus 로고
    • TNFR1-induced activation of the classical NF-kappaB pathway
    • Wajant H, Scheurich P. TNFR1-induced activation of the classical NF-kappaB pathway. FEBS J. 2011 ; 278: 862-876
    • (2011) FEBS J , vol.278 , pp. 862-876
    • Wajant, H.1    Scheurich, P.2
  • 24
    • 5444254408 scopus 로고    scopus 로고
    • Toll-like receptors in the pathogenesis of human disease
    • Cook DN, Pisetsky DS, Schwartz DA. Toll-like receptors in the pathogenesis of human disease. Nat Immunol. 2004 ; 5: 975-979
    • (2004) Nat Immunol , vol.5 , pp. 975-979
    • Cook, D.N.1    Pisetsky, D.S.2    Schwartz, D.A.3
  • 25
    • 33646543284 scopus 로고    scopus 로고
    • The modulation of inflammatory gene expression by lipids: Mediation through Toll-like receptors
    • Lee JY, Hwang DH. The modulation of inflammatory gene expression by lipids: mediation through Toll-like receptors. Mol Cell. 2006 ; 21: 174-185
    • (2006) Mol Cell , vol.21 , pp. 174-185
    • Lee, J.Y.1    Hwang, D.H.2
  • 26
    • 79960073532 scopus 로고    scopus 로고
    • A trio of microRNAs that control Toll-like receptor signalling
    • Quinn SR, O'Neill LA. A trio of microRNAs that control Toll-like receptor signalling. Int Immunol. 2011 ; 23: 421-425
    • (2011) Int Immunol , vol.23 , pp. 421-425
    • Quinn, S.R.1    O'Neill, L.A.2
  • 27
    • 75649113377 scopus 로고    scopus 로고
    • Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21
    • Sheedy FJ, Palsson-McDermott E, Hennessy EJ, Martin C, O'Leary JJ, Ruan Q, et al. Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21. Nat Immunol. 2010 ; 11: 141-147
    • (2010) Nat Immunol , vol.11 , pp. 141-147
    • Sheedy, F.J.1    Palsson-Mcdermott, E.2    Hennessy, E.J.3    Martin, C.4    O'Leary, J.J.5    Ruan, Q.6
  • 28
    • 33747608638 scopus 로고    scopus 로고
    • NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
    • Taganov KD, Boldin MP, Chang KJ, Baltimore D. NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA. 2006 ; 103: 12481-12486
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12481-12486
    • Taganov, K.D.1    Boldin, M.P.2    Chang, K.J.3    Baltimore, D.4
  • 29
    • 79952186298 scopus 로고    scopus 로고
    • MicroRNAs: The fine-tuners of Toll-like receptor signalling
    • O'Neill LA, Sheedy FJ, McCoy CE. MicroRNAs: the fine-tuners of Toll-like receptor signalling. Nat Rev Immunol. 2011 ; 11: 163-175
    • (2011) Nat Rev Immunol , vol.11 , pp. 163-175
    • O'Neill, L.A.1    Sheedy, F.J.2    McCoy, C.E.3
  • 30
    • 0036056315 scopus 로고    scopus 로고
    • Toll-like receptors: A family of pattern-recognition receptors in mammals
    • REVIEWS
    • Armant MA, Fenton MJ. Toll-like receptors: a family of pattern-recognition receptors in mammals. Genome Biol. 2002 ; 3: REVIEWS, 3011.1-3011.6 - REVIEWS, 3011.1-3011.6
    • (2002) Genome Biol , vol.3 , pp. 30111-30116
    • Armant, M.A.1    Fenton, M.J.2
  • 32
    • 0034617274 scopus 로고    scopus 로고
    • Cellular events mediated by lipopolysaccharide-stimulated toll-like receptor 4. MD-2 is required for activation of mitogen-activated protein kinases and Elk-1
    • Yang H, Young DW, Gusovsky F, Chow JC. Cellular events mediated by lipopolysaccharide-stimulated toll-like receptor 4. MD-2 is required for activation of mitogen-activated protein kinases and Elk-1. J Biol Chem. 2000 ; 275: 20861-20866
    • (2000) J Biol Chem , vol.275 , pp. 20861-20866
    • Yang, H.1    Young, D.W.2    Gusovsky, F.3    Chow, J.C.4
  • 33
    • 1642529500 scopus 로고    scopus 로고
    • Isolation of an endotoxin-MD-2 complex that produces Toll-like receptor 4-dependent cell activation at picomolar concentrations
    • Gioannini TL, Teghanemt A, Zhang D, Coussens NP, Dockstader W, Ramaswamy S, et al. Isolation of an endotoxin-MD-2 complex that produces Toll-like receptor 4-dependent cell activation at picomolar concentrations. Proc Natl Acad Sci USA. 2004 ; 101: 4186-4191
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4186-4191
    • Gioannini, T.L.1    Teghanemt, A.2    Zhang, D.3    Coussens, N.P.4    Dockstader, W.5    Ramaswamy, S.6
  • 34
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 2001 ; 25: 402-408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 35
    • 77950282576 scopus 로고    scopus 로고
    • MicroRNA-21 is upregulated during the proliferative phase of liver regeneration, targets Pellino-1, and inhibits NF-kappaB signaling
    • Marquez RT, Wendlandt E, Galle CS, Keck K, McCaffrey AP. MicroRNA-21 is upregulated during the proliferative phase of liver regeneration, targets Pellino-1, and inhibits NF-kappaB signaling. Am J Physiol Gastrointest Liver Physiol. 2010 ; 298: G535 - G541
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.298
    • Marquez, R.T.1    Wendlandt, E.2    Galle, C.S.3    Keck, K.4    McCaffrey, A.P.5
  • 36
    • 56149103896 scopus 로고    scopus 로고
    • Macrophage polarization in bacterial infections
    • Benoit M, Desnues B, Mege JL. Macrophage polarization in bacterial infections. J Immunol. 2008 ; 181: 3733-3739
    • (2008) J Immunol , vol.181 , pp. 3733-3739
    • Benoit, M.1    Desnues, B.2    Mege, J.L.3
  • 38
    • 68849085894 scopus 로고    scopus 로고
    • A cell biological view of Toll-like receptor function: Regulation through compartmentalization
    • Barton GM, Kagan JC. A cell biological view of Toll-like receptor function: regulation through compartmentalization. Nat Rev Immunol. 2009 ; 9: 535-542
    • (2009) Nat Rev Immunol , vol.9 , pp. 535-542
    • Barton, G.M.1    Kagan, J.C.2
  • 39
    • 56749185827 scopus 로고    scopus 로고
    • Adding fuel to fire: MicroRNAs as a new class of mediators of inflammation
    • Sheedy FJ, O'Neill LA. Adding fuel to fire: microRNAs as a new class of mediators of inflammation. Ann Rheum Dis. 2008 ; 67 (Suppl 3). iii50 - iii55
    • (2008) Ann Rheum Dis , vol.67 , Issue.SUPPL. 3
    • Sheedy, F.J.1    O'Neill, L.A.2
  • 40
    • 62649124147 scopus 로고    scopus 로고
    • Negative regulation of Toll-like receptor signaling pathway
    • Wang J, Hu Y, Deng WW, Sun B. Negative regulation of Toll-like receptor signaling pathway. Microbes Infect. 2009 ; 11: 321-327
    • (2009) Microbes Infect , vol.11 , pp. 321-327
    • Wang, J.1    Hu, Y.2    Deng, W.W.3    Sun, B.4
  • 41
    • 77955497665 scopus 로고    scopus 로고
    • The role of the miR-200 family in epithelial-mesenchymal transition
    • Mongroo PS, Rustgi AK. The role of the miR-200 family in epithelial-mesenchymal transition. Cancer Biol Ther. 2010 ; 10: 219-222
    • (2010) Cancer Biol Ther , vol.10 , pp. 219-222
    • Mongroo, P.S.1    Rustgi, A.K.2
  • 42
    • 53049097596 scopus 로고    scopus 로고
    • Hedgehog signaling, epithelial-to-mesenchymal transition and miRNA (review)
    • Katoh Y, Katoh M. Hedgehog signaling, epithelial-to-mesenchymal transition and miRNA (review). Int J Mol Med. 2008 ; 22: 271-275
    • (2008) Int J Mol Med , vol.22 , pp. 271-275
    • Katoh, Y.1    Katoh, M.2
  • 43
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep. 2008 ; 9: 582-589
    • (2008) EMBO Rep , vol.9 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3    Schmalhofer, O.4    Vincan, E.5    Spaderna, S.6
  • 44
    • 43049103824 scopus 로고    scopus 로고
    • The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
    • Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G, et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol. 2008 ; 10: 593-601
    • (2008) Nat Cell Biol , vol.10 , pp. 593-601
    • Gregory, P.A.1    Bert, A.G.2    Paterson, E.L.3    Barry, S.C.4    Tsykin, A.5    Farshid, G.6
  • 45
    • 0035064830 scopus 로고    scopus 로고
    • The sole gateway to endotoxin response: How LPS was identified as Tlr4, and its role in innate immunity
    • Beutler B, Poltorak A. The sole gateway to endotoxin response: how LPS was identified as Tlr4, and its role in innate immunity. Drug Metab Dispos. 2001 ; 29 (4 Pt 2). 474-478
    • (2001) Drug Metab Dispos , vol.29 , Issue.4 PART 2 , pp. 474-478
    • Beutler, B.1    Poltorak, A.2
  • 46
    • 33847311819 scopus 로고    scopus 로고
    • MicroRNAs and immunity: Tiny players in a big field
    • Taganov KD, Boldin MP, Baltimore D. MicroRNAs and immunity: tiny players in a big field. Immunity. 2007 ; 26: 133-137
    • (2007) Immunity , vol.26 , pp. 133-137
    • Taganov, K.D.1    Boldin, M.P.2    Baltimore, D.3
  • 48
    • 77958133262 scopus 로고    scopus 로고
    • Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation
    • Yan D, Ng WL, Zhang X, Wang P, Zhang Z, Mo YY, et al. Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation. PLoS One. 2010 ; 5: e11397 - e11397
    • (2010) PLoS One , vol.5
    • Yan, D.1    Ng, W.L.2    Zhang, X.3    Wang, P.4    Zhang, Z.5    Mo, Y.Y.6
  • 49
    • 78650658467 scopus 로고    scopus 로고
    • Inducible microRNA-155 feedback promotes type i IFN signaling in antiviral innate immunity by targeting suppressor of cytokine signaling 1
    • Wang P, Hou J, Lin L, Wang C, Liu X, Li D, et al. Inducible microRNA-155 feedback promotes type I IFN signaling in antiviral innate immunity by targeting suppressor of cytokine signaling 1. J Immunol. 2010 ; 185: 6226-6233
    • (2010) J Immunol , vol.185 , pp. 6226-6233
    • Wang, P.1    Hou, J.2    Lin, L.3    Wang, C.4    Liu, X.5    Li, D.6
  • 50
    • 49149091917 scopus 로고    scopus 로고
    • Regulation of IKKbeta by miR-199a affects NF-kappaB activity in ovarian cancer cells
    • Chen R, Alvero AB, Silasi DA, Kelly MG, Fest S, Visintin I, et al. Regulation of IKKbeta by miR-199a affects NF-kappaB activity in ovarian cancer cells. Oncogene. 2008 ; 27: 4712-4723
    • (2008) Oncogene , vol.27 , pp. 4712-4723
    • Chen, R.1    Alvero, A.B.2    Silasi, D.A.3    Kelly, M.G.4    Fest, S.5    Visintin, I.6
  • 51
    • 69249085731 scopus 로고    scopus 로고
    • Modulation of TLR2 protein expression by miR-105 in human oral keratinocytes
    • Benakanakere MR, Li Q, Eskan MA, Singh AV, Zhao J, Galicia JC, et al. Modulation of TLR2 protein expression by miR-105 in human oral keratinocytes. J Biol Chem. 2009 ; 284: 23107-23115
    • (2009) J Biol Chem , vol.284 , pp. 23107-23115
    • Benakanakere, M.R.1    Li, Q.2    Eskan, M.A.3    Singh, A.V.4    Zhao, J.5    Galicia, J.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.