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Volumn 41, Issue 4, 2012, Pages 1373-1380

Expression of melanocortin receptors in human prostate cancer cell lines: MC2R activation by ACTH increases prostate cancer cell proliferation

Author keywords

Adrenocorticotropic hormone; Androgen receptor; G protein coupledreceptors; Melanocortin receptor 2; Melanocortin receptors; Prostate cancer

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; CORTICOTROPIN; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; MELANOCORTIN 1 RECEPTOR; MELANOCORTIN 2 RECEPTOR; MELANOCORTIN 2 RECEPTOR ACCESSORY PROTEIN ALPHA; MELANOCORTIN 2 RECEPTOR ACCESSORY PROTEIN BETA; MELANOCORTIN 3 RECEPTOR; MELANOCORTIN 4 RECEPTOR; MELANOCORTIN 5 RECEPTOR; MESSENGER RNA; N ACETYL ALPHA INTERMEDIN[4-10]CYCLO[4 NORLEUCINE 5 ASPARTIC ACID 7 [3 (2 NAPHTHYL)ALANINE] 10 LYSINAMIDE]; PROTEIN; TESTOSTERONE; UNCLASSIFIED DRUG;

EID: 84866485226     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1574     Document Type: Article
Times cited : (10)

References (43)
  • 1
    • 0028883394 scopus 로고
    • Screening for prostate cancer with prostate-specific antigen. An examination of the evidence
    • Woolf SH: Screening for prostate cancer with prostate-specific antigen. An examination of the evidence. N Engl J Med 333: 1401-1405, 1995.
    • (1995) N Engl J Med , vol.333 , pp. 1401-1405
    • Woolf, S.H.1
  • 2
    • 0032323546 scopus 로고    scopus 로고
    • Management of hormone refractory prostate cancer: Current standards and future prospects
    • Oh WK, Kantoff PW: Management of hormone refractory prostate cancer: Current standards and future prospects. J Urol 160: 1220-1229, 1998.
    • (1998) J Urol , vol.160 , pp. 1220-1229
    • Oh, W.K.1    Kantoff, P.W.2
  • 3
    • 34250310422 scopus 로고    scopus 로고
    • A promoting role of androgen receptor in androgen-sensitive and -insensitive prostate cancer cells
    • Li TH, Zhao H, Peng Y, Beliakoff J, Brooks JD and Sun Z: A promoting role of androgen receptor in androgen-sensitive and -insensitive prostate cancer cells. Nucleic Acids Res 35: 2767-2776, 2007.
    • (2007) Nucleic Acids Res , vol.35 , pp. 2767-2776
    • Li, T.H.1    Zhao, H.2    Peng, Y.3    Beliakoff, J.4    Brooks, J.D.5    Sun, Z.6
  • 4
    • 0014151337 scopus 로고
    • Endocrine-induced regression of cancers
    • Huggins C: Endocrine-induced regression of cancers. Cancer Res 27: 1925-1930, 1967.
    • (1967) Cancer Res , vol.27 , pp. 1925-1930
    • Huggins, C.1
  • 5
    • 4744347762 scopus 로고    scopus 로고
    • Mechanisms of androgen-refractory prostate cancer
    • Debes JD, Tindall DJ: Mechanisms of androgen-refractory prostate cancer. N Engl J Med 351: 1488-1490, 2004.
    • (2004) N Engl J Med , vol.351 , pp. 1488-1490
    • Debes, J.D.1    Tindall, D.J.2
  • 6
    • 0035496220 scopus 로고    scopus 로고
    • The development of androgen-independent prostate cancer
    • Feldman BJ and Feldman D: The development of androgen-independent prostate cancer. Nat Rev Cancer 1: 34-45, 2001.
    • (2001) Nat Rev Cancer , vol.1 , pp. 34-45
    • Feldman, B.J.1    Feldman, D.2
  • 7
    • 43949123277 scopus 로고    scopus 로고
    • Manipulation of androgens and alterations in the androgen receptor axis in prostate cancer
    • Nguyen MM and Wang Z: Manipulation of androgens and alterations in the androgen receptor axis in prostate cancer. Minerva Urol Nefrol 60: 15-29, 2008.
    • (2008) Minerva Urol Nefrol , vol.60 , pp. 15-29
    • Nguyen, M.M.1    Wang, Z.2
  • 8
    • 0035930133 scopus 로고    scopus 로고
    • Androgen receptor signaling in androgen-refractory prostate cancer
    • Grossmann ME, Huang H, Tindall DJ: Androgen receptor signaling in androgen-refractory prostate cancer. J Natl Cancer Inst 93: 1687-1697, 2001.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1687-1697
    • Grossmann, M.E.1    Huang, H.2    Tindall, D.J.3
  • 9
    • 0033022342 scopus 로고    scopus 로고
    • A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase
    • Craft N, Shostak Y, Carey M and Sawyers CL: A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase. Nat Med 5: 280-285, 1999.
    • (1999) Nat Med , vol.5 , pp. 280-285
    • Craft, N.1    Shostak, Y.2    Carey, M.3    Sawyers, C.L.4
  • 10
    • 12344319442 scopus 로고    scopus 로고
    • Alterations of androgen receptor in prostate cancer
    • Linja MJ and Visakorpi T: Alterations of androgen receptor in prostate cancer. J Steroid Biochem Mol Biol 92: 255-264, 2004.
    • (2004) J Steroid Biochem Mol Biol , vol.92 , pp. 255-264
    • Linja, M.J.1    Visakorpi, T.2
  • 11
    • 69849085455 scopus 로고    scopus 로고
    • Key targets of hormonal treatment of prostate cancer. Part 1: The androgen receptor and steroidogenic pathways
    • Vis AN and Schröder FH: Key targets of hormonal treatment of prostate cancer. Part 1: the androgen receptor and steroidogenic pathways. BJU Int 104: 438-448, 2009.
    • (2009) BJU Int , vol.104 , pp. 438-448
    • Vis, A.N.1    Schröder, F.H.2
  • 12
    • 0028912810 scopus 로고
    • Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor and epidermal growth factor
    • Culig Z, Hobisch A, Cronauer MV, et al: Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor and epidermal growth factor. Eur Urol 27 (Suppl 2): 45-47, 1995.
    • (1995) Eur Urol , vol.27 , Issue.SUPPL. 2 , pp. 45-47
    • Culig, Z.1    Hobisch, A.2    Cronauer, M.V.3
  • 13
    • 33846474121 scopus 로고    scopus 로고
    • G-protein-coupled receptors and cancer
    • Dorsam RT and Gutkind JS: G-protein-coupled receptors and cancer. Nat Rev Cancer 7: 79-94, 2007.
    • (2007) Nat Rev Cancer , vol.7 , pp. 79-94
    • Dorsam, R.T.1    Gutkind, J.S.2
  • 14
    • 1542290456 scopus 로고    scopus 로고
    • G proteins in cancer: The prostate cancer paradigm
    • Daaka Y: G proteins in cancer: The prostate cancer paradigm. Sci STKE: re2, 2004.
    • (2004) Sci STKE
    • Daaka, Y.1
  • 15
    • 34250900516 scopus 로고    scopus 로고
    • Current standard and investigational approaches to the management of hormone-refractory prostate cancer
    • Mendiratta P, Armstrong AJ and George DJ: Current standard and investigational approaches to the management of hormone-refractory prostate cancer. Rev Urol 9: S9-S19, 2007.
    • (2007) Rev Urol , vol.9
    • Mendiratta, P.1    Armstrong, A.J.2    George, D.J.3
  • 16
    • 0036165295 scopus 로고    scopus 로고
    • Guanosine phosphate binding protein coupled receptors in prostate cancer: A review
    • Raj GV, Barki-Harrington L, Kue PF and Daaka Y: Guanosine phosphate binding protein coupled receptors in prostate cancer: A review. J Urol 167: 1458-1463, 2002.
    • (2002) J Urol , vol.167 , pp. 1458-1463
    • Raj, G.V.1    Barki-Harrington, L.2    Kue, P.F.3    Daaka, Y.4
  • 17
    • 0035855662 scopus 로고    scopus 로고
    • Identification of a prostate-specific G-protein coupled receptor in prostate cancer
    • Xia C, Ma W, Wang F, Hua SB, Liu M: Identification of a prostate-specific G-protein coupled receptor in prostate cancer. Oncogene 13: 5903-5907, 2001.
    • (2001) Oncogene , vol.13 , pp. 5903-5907
    • Xia, C.1    Ma, W.2    Wang, F.3    Hua, S.B.4    Liu, M.5
  • 18
    • 33646735987 scopus 로고    scopus 로고
    • The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase
    • Wang J, Weng J, Cai Y, Penland R, Liu M, Ittmann M: The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase. Prostate 1: 847-857, 2006.
    • (2006) Prostate , vol.1 , pp. 847-857
    • Wang, J.1    Weng, J.2    Cai, Y.3    Penland, R.4    Liu, M.5    Ittmann, M.6
  • 19
    • 11944266934 scopus 로고    scopus 로고
    • Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers
    • Weng J, Wang J, Cai Y, et al: Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers. Int J Cancer 113: 811-818, 2005.
    • (2005) Int J Cancer , vol.113 , pp. 811-818
    • Weng, J.1    Wang, J.2    Cai, Y.3
  • 20
    • 0041508658 scopus 로고    scopus 로고
    • G protein-coupled receptors provide survival signals in prostate cancer
    • Yowell CW and Daaka Y: G protein-coupled receptors provide survival signals in prostate cancer. Clin Prostate Cancer 1: 177-181, 2002.
    • (2002) Clin Prostate Cancer , vol.1 , pp. 177-181
    • Yowell, C.W.1    Daaka, Y.2
  • 21
    • 80051748146 scopus 로고    scopus 로고
    • Investigation of cancer cell lines for peptide receptor-targeted drug development
    • Sun L, Luo J, Mackey LV, et al: Investigation of cancer cell lines for peptide receptor-targeted drug development. J Drug Target 19: 719-730, 2011.
    • (2011) J Drug Target , vol.19 , pp. 719-730
    • Sun, L.1    Luo, J.2    Mackey, L.V.3
  • 22
    • 0034636685 scopus 로고    scopus 로고
    • Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors
    • Gutkind JS: Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors. Sci STKE: re1, 2000.
    • (2000) Sci STKE
    • Gutkind, J.S.1
  • 23
    • 0027093255 scopus 로고
    • Expression of the Protooncogene bcl-2 in the Prostate and Its Association with Emergence of Androgen-independent Prostate Cancer
    • McDonnell TJ, Troncoso P, Brisbay SM, et al: Expression of the Protooncogene bcl-2 in the Prostate and Its Association with Emergence of Androgen-independent Prostate Cancer. Cancer Res 52: 6940-6944, 1992.
    • (1992) Cancer Res , vol.52 , pp. 6940-6944
    • McDonnell, T.J.1    Troncoso, P.2    Brisbay, S.M.3
  • 24
    • 15744379004 scopus 로고    scopus 로고
    • Androgen receptor activation by G (s) signaling in prostate cancer cells
    • Kasbohm EA, Guo R, Yowell CW, et al: Androgen receptor activation by G (s) signaling in prostate cancer cells. J Biol Chem 280: 11583-11589, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 11583-11589
    • Kasbohm, E.A.1    Guo, R.2    Yowell, C.W.3
  • 25
    • 78650413899 scopus 로고    scopus 로고
    • Roles of cAMP and cAMP-dependent protein kinase in the progression of prostate cancer: Cross-talk with the androgen receptor
    • Merkle D and Hoffmann R: Roles of cAMP and cAMP-dependent protein kinase in the progression of prostate cancer: Cross-talk with the androgen receptor. Cell Signal 23: 507-515, 2011.
    • (2011) Cell Signal , vol.23 , pp. 507-515
    • Merkle, D.1    Hoffmann, R.2
  • 26
    • 0035900805 scopus 로고    scopus 로고
    • Prostate cancer risk: Associations with ultraviolet radiation, tyrosinase and melanocortin-1 receptor genotypes
    • Luscombe CJ, French ME, Liu S, et al: Prostate cancer risk: Associations with ultraviolet radiation, tyrosinase and melanocortin-1 receptor genotypes. Br J Cancer 85: 1504-1509, 2001.
    • (2001) Br J Cancer , vol.85 , pp. 1504-1509
    • Luscombe, C.J.1    French, M.E.2    Liu, S.3
  • 27
    • 0034919731 scopus 로고    scopus 로고
    • Reversal of cancer anorexia by blockade of central melanocortin receptors in rats
    • Wisse BE, Frayo RS, Schwartz MW and Cummings DE: Reversal of cancer anorexia by blockade of central melanocortin receptors in rats. Endocrinology 142: 3292-3301, 2001.
    • (2001) Endocrinology , vol.142 , pp. 3292-3301
    • Wisse, B.E.1    Frayo, R.S.2    Schwartz, M.W.3    Cummings, D.E.4
  • 28
    • 0031442053 scopus 로고    scopus 로고
    • Exocrine gland dysfunction in MC5-R-deficient mice: Evidence for coordinated regulation of exocrine gland function by melanocortin peptides
    • Chen W, Kelly MA, Opitz-Araya X, Thomas RE, Low MJ and Cone RD: Exocrine gland dysfunction in MC5-R-deficient mice: Evidence for coordinated regulation of exocrine gland function by melanocortin peptides. Cell 91: 789-798, 1997.
    • (1997) Cell , vol.91 , pp. 789-798
    • Chen, W.1    Kelly, M.A.2    Opitz-Araya, X.3    Thomas, R.E.4    Low, M.J.5    Cone, R.D.6
  • 29
    • 79952068392 scopus 로고    scopus 로고
    • Adreno-corticotropin hormone (ACTH) effects on MAPK phosphorylation in human fasciculata cells and in embryonic kidney 293 cells expressing human melanocortin 2 receptor (MC2R) and MC2R accessory protein (MRAP)β
    • Roy S, Pinard S, Chouinard L and Gallo-Payet N: Adreno-corticotropin hormone (ACTH) effects on MAPK phosphorylation in human fasciculata cells and in embryonic kidney 293 cells expressing human melanocortin 2 receptor (MC2R) and MC2R accessory protein (MRAP)β. Mol Cell Endocrinol 336: 31-40, 2011.
    • (2011) Mol Cell Endocrinol , vol.336 , pp. 31-40
    • Roy, S.1    Pinard, S.2    Chouinard, L.3    Gallo-Payet, N.4
  • 30
    • 67849106829 scopus 로고    scopus 로고
    • Cushing's syndrome due to ectopic ACTH production by (neuroendocrine) prostate carcinoma
    • Alwani RA, Neggers SJ, van der Klift M, et al: Cushing's syndrome due to ectopic ACTH production by (neuroendocrine) prostate carcinoma. Pituitary 12: 280-283, 2009.
    • (2009) Pituitary , vol.12 , pp. 280-283
    • Alwani, R.A.1    Neggers, S.J.2    Van Der Klift, M.3
  • 31
    • 78651234318 scopus 로고    scopus 로고
    • Thiazolidinediones/PPARγ agonists and fatty acid synthase inhibitors as an experimental combination therapy for prostate cancer
    • Mansour M, Schwartz D, Judd R, et al: Thiazolidinediones/PPARγ agonists and fatty acid synthase inhibitors as an experimental combination therapy for prostate cancer. Int J Oncol 38: 537-546, 2011.
    • (2011) Int J Oncol , vol.38 , pp. 537-546
    • Mansour, M.1    Schwartz, D.2    Judd, R.3
  • 33
    • 75949102364 scopus 로고    scopus 로고
    • Pancreatic neuronal melanocortin-4 receptor modulates serum insulin levels independent of leptin receptor
    • Mansour M, White D, Wernette C, et al: Pancreatic neuronal melanocortin-4 receptor modulates serum insulin levels independent of leptin receptor. Endocrine 37: 220-230, 2010.
    • (2010) Endocrine , vol.37 , pp. 220-230
    • Mansour, M.1    White, D.2    Wernette, C.3
  • 34
    • 0035398487 scopus 로고    scopus 로고
    • G-protein-coupled receptors and signaling networks: Emerging paradigms
    • Marinissen MJ and Gutkind JS: G-protein-coupled receptors and signaling networks: emerging paradigms. Trends Pharmacol Sci 22: 368-376, 2001.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 368-376
    • Marinissen, M.J.1    Gutkind, J.S.2
  • 36
    • 34347210358 scopus 로고    scopus 로고
    • Differential regulation of the human adrenocorticotropin receptor [melanocortin-2 receptor (MC2R)] by human MC2R accessory protein isoforms alpha and beta in isogenic human embryonic kidney 293 cells
    • Roy S, Rached M and Gallo-Payet N: Differential regulation of the human adrenocorticotropin receptor [melanocortin-2 receptor (MC2R)] by human MC2R accessory protein isoforms alpha and beta in isogenic human embryonic kidney 293 cells. Mol Endocrinol 21: 1656-1669, 2007.
    • (2007) Mol Endocrinol , vol.21 , pp. 1656-1669
    • Roy, S.1    Rached, M.2    Gallo-Payet, N.3
  • 37
    • 33845572889 scopus 로고    scopus 로고
    • Studies on the physiological functions of the melanocortin system
    • Cone RD: Studies on the physiological functions of the melanocortin system. Endocr Rev 27: 736-749, 2006.
    • (2006) Endocr Rev , vol.27 , pp. 736-749
    • Cone, R.D.1
  • 38
    • 0028920049 scopus 로고
    • Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides
    • Abdel-Malek Z, Swope VB, Suzuki I, et al: Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides. Proc Natl Acad Sci USA 92: 1789-1793, 1995.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1789-1793
    • Abdel-Malek, Z.1    Swope, V.B.2    Suzuki, I.3
  • 39
    • 79955093923 scopus 로고    scopus 로고
    • Pathogenesis of pituitary tumors
    • Melmed S: Pathogenesis of pituitary tumors. Nat Rev Endocrinol 7: 257-266, 2011.
    • (2011) Nat Rev Endocrinol , vol.7 , pp. 257-266
    • Melmed, S.1
  • 40
    • 0001037775 scopus 로고
    • Nonpituitary neoplasms and cushing's syndrome: Ectopic 'adrenocorticotropin' produced by nonpituitary neoplasms as a cause of Cushing's syndrome
    • Liddle GW, Island DP, Ney RL, Nicholson WE and Shimizu N: Nonpituitary neoplasms and cushing's syndrome: Ectopic 'adrenocorticotropin' produced by nonpituitary neoplasms as a cause of Cushing's syndrome. Arch Intern Med 111: 471-475, 1963.
    • (1963) Arch Intern Med , vol.111 , pp. 471-475
    • Liddle, G.W.1    Island, D.P.2    Ney, R.L.3    Nicholson, W.E.4    Shimizu, N.5
  • 41
    • 0016382152 scopus 로고
    • Ectopic ACTH production in carcinoma of the lung
    • Gewirtz G and Yalow RS: Ectopic ACTH production in carcinoma of the lung. J Clin Invest 53: 1022-1032, 1974.
    • (1974) J Clin Invest , vol.53 , pp. 1022-1032
    • Gewirtz, G.1    Yalow, R.S.2
  • 42
    • 0018194917 scopus 로고
    • Ectopic ACTH syndrome: Clinicopathological correlations
    • Singer W, Kovacs K, Ryan N and Horvath E: Ectopic ACTH syndrome: clinicopathological correlations. J Clin Pathol 31: 591-598, 1978.
    • (1978) J Clin Pathol , vol.31 , pp. 591-598
    • Singer, W.1    Kovacs, K.2    Ryan, N.3    Horvath, E.4
  • 43
    • 0016657068 scopus 로고
    • Cyclic AMP and adrenocortical function
    • Halkerston ID: Cyclic AMP and adrenocortical function. Adv Cyclic Nucleotide Res 6: 99-136, 1975.
    • (1975) Adv Cyclic Nucleotide Res , vol.6 , pp. 99-136
    • Halkerston, I.D.1


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