메뉴 건너뛰기




Volumn 28, Issue 4, 2012, Pages 1503-1511

Prognostic impact of δ-like ligand 4 and Notch1 in acute myeloid leukemia

Author keywords

like ligand 4; Acute myeloid leukemia; Angiogenesis; Notch1; Prognosis

Indexed keywords

ANGIOPOIETIN; DELTA LIKE LIGAND 4 PROTEIN; MEMBRANE PROTEIN; NOTCH1 RECEPTOR; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

EID: 84866462073     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1943     Document Type: Article
Times cited : (14)

References (45)
  • 1
    • 79951852902 scopus 로고    scopus 로고
    • Ovarian cancer-associated fibroblasts contribute to epithelial ovarian carcinoma metastasis by promoting angiogenesis, lymphangiogenesis and tumor cell invasion
    • Zhang Y, Tang H, Cai J, et al: Ovarian cancer-associated fibroblasts contribute to epithelial ovarian carcinoma metastasis by promoting angiogenesis, lymphangiogenesis and tumor cell invasion. Cancer Lett 303: 47-55, 2011.
    • (2011) Cancer Lett , vol.303 , pp. 47-55
    • Zhang, Y.1    Tang, H.2    Cai, J.3
  • 2
    • 78650329024 scopus 로고    scopus 로고
    • Angiogenesis blockade as therapy for hepatocellular carcinoma: Progress and challenges
    • Hao CY: Angiogenesis blockade as therapy for hepatocellular carcinoma: progress and challenges. J Gastroenterol Hepatol 26: 4-6, 2011.
    • (2011) J Gastroenterol Hepatol , vol.26 , pp. 4-6
    • Hao, C.Y.1
  • 3
    • 65349115448 scopus 로고    scopus 로고
    • Bone marrow angiogenesis magnetic resonance imaging in patients with acute myeloid leukemia: Peak enhancement ratio is an independent predictor for overall survival
    • Shih TT, Hou HA, Liu CY, et al: Bone marrow angiogenesis magnetic resonance imaging in patients with acute myeloid leukemia: peak enhancement ratio is an independent predictor for overall survival. Blood 113: 3161-3167, 2009.
    • (2009) Blood , vol.113 , pp. 3161-3167
    • Shih, T.T.1    Hou, H.A.2    Liu, C.Y.3
  • 4
    • 81555220915 scopus 로고    scopus 로고
    • Angiogenesis in acute myeloid leukemia and opportunities for novel therapies
    • Trujillo A, McGee C and Cogle CR: Angiogenesis in acute myeloid leukemia and opportunities for novel therapies. J Oncol 2012: 128608, 2012.
    • (2012) J Oncol , vol.2012 , pp. 128608
    • Trujillo, A.1    McGee, C.A.2    Cogle, C.R.3
  • 5
    • 79953154623 scopus 로고    scopus 로고
    • Influence of the tumor microenvironment on angiogenesis
    • Payne SJ and Jones L: Influence of the tumor microenvironment on angiogenesis. Future Oncol 7: 395-408, 2011.
    • (2011) Future Oncol , vol.7 , pp. 395-408
    • Payne, S.J.A.1    Jones, L.2
  • 6
    • 74049121331 scopus 로고    scopus 로고
    • Contribution of bone microenvironment to leukemogenesis and leukemia progression
    • Ayala F, Dewar R, Kieran M and Kalluri R: Contribution of bone microenvironment to leukemogenesis and leukemia progression. Leukemia 23: 2233-2241, 2009.
    • (2009) Leukemia , vol.23 , pp. 2233-2241
    • Ayala, F.1    Dewar, R.2    Kieran, M.A.3    Kalluri, R.4
  • 7
    • 40849088142 scopus 로고    scopus 로고
    • Expression of angiopoietins and vascular endothelial growth factors and their clinical significance in acute myeloid leukemia
    • Hou HA, Chou WC, Lin LI, et al: Expression of angiopoietins and vascular endothelial growth factors and their clinical significance in acute myeloid leukemia. Leuk Res 32: 904-912, 2008.
    • (2008) Leuk Res , vol.32 , pp. 904-912
    • Hou, H.A.1    Chou, W.C.2    Lin, L.I.3
  • 8
    • 79956328903 scopus 로고    scopus 로고
    • Molecular mechanisms and clinical applications of angiogenesis
    • Carmeliet P and Jain RK: Molecular mechanisms and clinical applications of angiogenesis. Nature 473: 298-307, 2011.
    • (2011) Nature , vol.473 , pp. 298-307
    • Carmeliet, P.A.1    Jain, R.K.2
  • 11
    • 4544290590 scopus 로고    scopus 로고
    • Angiopoietins in tumours: The angiogenic switch
    • Tait CR and Jones PF: Angiopoietins in tumours: the angiogenic switch. J Pathol 204: 1-10, 2004.
    • (2004) J Pathol , vol.204 , pp. 1-10
    • Tait, C.R.A.1    Jones, P.F.2
  • 12
    • 74549166057 scopus 로고    scopus 로고
    • Targeting the angiopoietin (Ang)/Tie-2 pathway in the crosstalk between acute myeloid leukaemia and endothelial cells: Studies of Tie-2 blocking antibodies, exogenous Ang-2 and inhibition of constitutive agonistic Ang-1 release
    • Reikvam H, Hatfield KJ, Lassalle P, Kittang AO, Ersvaer E and Bruserud O: Targeting the angiopoietin (Ang)/Tie-2 pathway in the crosstalk between acute myeloid leukaemia and endothelial cells: studies of Tie-2 blocking antibodies, exogenous Ang-2 and inhibition of constitutive agonistic Ang-1 release. Expert Opin Investig Drugs 19: 169-183, 2010.
    • (2010) Expert Opin Investig Drugs , vol.19 , pp. 169-183
    • Reikvam, H.1    Hatfield, K.J.2    Lassalle, P.3    Kittang, A.O.4    Ersvaer, E.A.5    Bruserud, O.6
  • 13
    • 77649190207 scopus 로고    scopus 로고
    • Increased angiogenesis induced by chronic lymphocytic leukemia B cells is mediated by leukemia-derived Ang2 and VEGF
    • Maffei R, Martinelli S, Castelli I, et al: Increased angiogenesis induced by chronic lymphocytic leukemia B cells is mediated by leukemia-derived Ang2 and VEGF. Leuk Res 34: 312-321, 2010.
    • (2010) Leuk Res , vol.34 , pp. 312-321
    • Maffei, R.1    Martinelli, S.2    Castelli, I.3
  • 14
    • 34047224675 scopus 로고    scopus 로고
    • Regulation of angiogenesis in the bone marrow of myelodysplastic syndromes transforming to overt leukaemia
    • Keith T, Araki Y, Ohyagi M, et al: Regulation of angiogenesis in the bone marrow of myelodysplastic syndromes transforming to overt leukaemia. Br J Haematol 137: 206-215, 2007.
    • (2007) Br J Haematol , vol.137 , pp. 206-215
    • Keith, T.1    Araki, Y.2    Ohyagi, M.3
  • 15
    • 0036841072 scopus 로고    scopus 로고
    • Plasma vascular endothelial growth factor levels have prognostic significance in patients with acute myeloid leukemia but not in patients with myelodysplastic syndromes
    • Aguayo A, Kantarjian HM, Estey EH, et al: Plasma vascular endothelial growth factor levels have prognostic significance in patients with acute myeloid leukemia but not in patients with myelodysplastic syndromes. Cancer 95: 1923-1930, 2002.
    • (2002) Cancer , vol.95 , pp. 1923-1930
    • Aguayo, A.1    Kantarjian, H.M.2    Estey, E.H.3
  • 16
    • 0036718433 scopus 로고    scopus 로고
    • Vascular endothelial growth factor secretion is an independent prognostic factor for relapse-free survival in pediatric acute myeloid leukemia patients
    • de Bont ES, Fidler V, Meeuwsen T, Scherpen F, Hahlen K and Kamps WA: Vascular endothelial growth factor secretion is an independent prognostic factor for relapse-free survival in pediatric acute myeloid leukemia patients. Clin Cancer Res 8: 2856-2861, 2002.
    • (2002) Clin Cancer Res , vol.8 , pp. 2856-2861
    • De Bont, E.S.1    Fidler, V.2    Meeuwsen, T.3    Scherpen, F.4    Hahlen, K.A.5    Kamps, W.A.6
  • 17
    • 20044371963 scopus 로고    scopus 로고
    • Analysis of concerted expression of angiogenic growth factors in acute myeloid leukemia: Expression of angiopoietin-2 represents an independent prognostic factor for overall survival
    • Loges S, Heil G, Bruweleit M, et al: Analysis of concerted expression of angiogenic growth factors in acute myeloid leukemia: expression of angiopoietin-2 represents an independent prognostic factor for overall survival. J Clin Oncol 23: 1109-1117, 2005.
    • (2005) J Clin Oncol , vol.23 , pp. 1109-1117
    • Loges, S.1    Heil, G.2    Bruweleit, M.3
  • 18
    • 34548128334 scopus 로고    scopus 로고
    • Circulating angiopoietin-2 is a strong prognostic factor in acute myeloid leukemia
    • Schliemann C, Bieker R, Thoennissen N, et al: Circulating angiopoietin-2 is a strong prognostic factor in acute myeloid leukemia. Leukemia 21: 1901-1906, 2007.
    • (2007) Leukemia , vol.21 , pp. 1901-1906
    • Schliemann, C.1    Bieker, R.2    Thoennissen, N.3
  • 19
    • 77951139188 scopus 로고    scopus 로고
    • Therapeutic antibody targeting of individual Notch receptors
    • Wu Y, Cain-Hom C, Choy L, et al: Therapeutic antibody targeting of individual Notch receptors. Nature 464: 1052-1057, 2010.
    • (2010) Nature , vol.464 , pp. 1052-1057
    • Wu, Y.1    Cain-Hom, C.2    Choy, L.3
  • 20
    • 79953123792 scopus 로고    scopus 로고
    • Notch is oncogenic dominant in T-cell acute lymphoblastic leukemia
    • Demarest RM, Dahmane N and Capobianco AJ: Notch is oncogenic dominant in T-cell acute lymphoblastic leukemia. Blood 117: 2901-2909, 2011.
    • (2011) Blood , vol.117 , pp. 2901-2909
    • Demarest, R.M.1    Dahmane, N.A.2    Capobianco, A.J.3
  • 21
    • 33644782668 scopus 로고    scopus 로고
    • Recent insights into the role of Notch signaling in tumorigenesis
    • Leong KG and Karsan A: Recent insights into the role of Notch signaling in tumorigenesis. Blood 107: 2223-2233, 2006.
    • (2006) Blood , vol.107 , pp. 2223-2233
    • Leong, K.G.A.1    Karsan, A.2
  • 22
    • 59649085554 scopus 로고    scopus 로고
    • Angiogenesis: A team effort coordinated by notch
    • Phng LK and Gerhardt H: Angiogenesis: a team effort coordinated by notch. Dev Cell 16: 196-208, 2009.
    • (2009) Dev Cell , vol.16 , pp. 196-208
    • Phng, L.K.1    Gerhardt, H.2
  • 23
    • 22244461524 scopus 로고    scopus 로고
    • Notch signaling from tumor cells: A new mechanism of angiogenesis
    • Li JL and Harris AL: Notch signaling from tumor cells: a new mechanism of angiogenesis. Cancer Cell 8: 1-3, 2005.
    • (2005) Cancer Cell , vol.8 , pp. 1-3
    • Li, J.L.A.1    Harris, A.L.2
  • 24
    • 33845907380 scopus 로고    scopus 로고
    • Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis
    • Ridgway J, Zhang G, Wu Y, et al: Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis. Nature 444: 1083-1087, 2006.
    • (2006) Nature , vol.444 , pp. 1083-1087
    • Ridgway, J.1    Zhang, G.2    Wu, Y.3
  • 25
    • 33845877157 scopus 로고    scopus 로고
    • Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis
    • Noguera-Troise I, Daly C, Papadopoulos NJ, et al: Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis. Nature 444: 1032-1037, 2006.
    • (2006) Nature , vol.444 , pp. 1032-1037
    • Noguera-Troise, I.1    Daly, C.2    Papadopoulos, N.J.3
  • 26
    • 80555129351 scopus 로고    scopus 로고
    • Oncogenic and tumor suppressor functions of Notch in cancer: It's NOTCH what you think
    • Lobry C, Oh P and Aifantis I: Oncogenic and tumor suppressor functions of Notch in cancer: it's NOTCH what you think. J Exp Med 208: 1931-1935, 2011.
    • (2011) J Exp Med , vol.208 , pp. 1931-1935
    • Lobry, C.1    Oh, P.A.2    Aifantis, I.3
  • 27
    • 0037143737 scopus 로고    scopus 로고
    • Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo
    • Lobov IB, Brooks PC and Lang RA: Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo. Proc Natl Acad Sci USA 99: 11205-11210, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 11205-11210
    • Lobov, I.B.1    Brooks, P.C.A.2    Lang, R.A.3
  • 28
    • 63849310246 scopus 로고    scopus 로고
    • Crosstalk of VEGF and Notch pathways in tumour angiogenesis: Therapeutic implications
    • Li JL and Harris AL: Crosstalk of VEGF and Notch pathways in tumour angiogenesis: therapeutic implications. Front Biosci 14: 3094-3110, 2009.
    • (2009) Front Biosci , vol.14 , pp. 3094-3110
    • Li, J.L.A.1    Harris, A.L.2
  • 29
    • 53849106782 scopus 로고    scopus 로고
    • VEGF and Delta-Notch: Interacting signalling pathways in tumour angiogenesis
    • Thurston G and Kitajewski J: VEGF and Delta-Notch: interacting signalling pathways in tumour angiogenesis. Br J Cancer 99: 1204-1209, 2008.
    • (2008) Br J Cancer , vol.99 , pp. 1204-1209
    • Thurston, G.A.1    Kitajewski, J.2
  • 30
    • 46749099009 scopus 로고    scopus 로고
    • Ethanol stimulates endothelial cell angiogenic activity via a Notch- And angiopoietin-1-dependent pathway
    • Morrow D, Cullen JP, Cahill PA and Redmond EM: Ethanol stimulates endothelial cell angiogenic activity via a Notch- and angiopoietin-1-dependent pathway. Cardiovasc Res 79: 313-321, 2008.
    • (2008) Cardiovasc Res , vol.79 , pp. 313-321
    • Morrow, D.1    Cullen, J.P.2    Cahill, P.A.A.3    Redmond, E.M.4
  • 31
    • 79953131280 scopus 로고    scopus 로고
    • Angiopoietin-1/Tie2 signal augments basal Notch signal controlling vascular quiescence by inducing delta-like 4 expression through AKT-mediated activation of beta-catenin
    • Zhang J, Fukuhara S, Sako K, et al: Angiopoietin-1/Tie2 signal augments basal Notch signal controlling vascular quiescence by inducing delta-like 4 expression through AKT-mediated activation of beta-catenin. J Biol Chem 286: 8055-8066, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 8055-8066
    • Zhang, J.1    Fukuhara, S.2    Sako, K.3
  • 32
    • 78650684200 scopus 로고    scopus 로고
    • The chemokine network in acute myelogenous leukemia: Molecular mechanisms involved in leukemogenesis and therapeutic implications
    • Kittang AO, Hatfield K, Sand K, Reikvam H and Bruserud O: The chemokine network in acute myelogenous leukemia: molecular mechanisms involved in leukemogenesis and therapeutic implications. Curr Top Microbiol Immunol 341: 149-172, 2010.
    • (2010) Curr Top Microbiol Immunol , vol.341 , pp. 149-172
    • Kittang, A.O.1    Hatfield, K.2    Sand, K.3    Reikvam, H.A.4    Bruserud, O.5
  • 33
    • 33747821158 scopus 로고    scopus 로고
    • Comparison of five prognostic scoring systems, the French-American- British (FAB) and World Health Organization (WHO) classifications in patients with myelodysplastic syndromes: Results of a single-center analysis
    • Muller-Berndorff H, Haas PS, Kunzmann R, Schulte-Monting J and Lubbert M: Comparison of five prognostic scoring systems, the French-American-British (FAB) and World Health Organization (WHO) classifications in patients with myelodysplastic syndromes: Results of a single-center analysis. Ann Hematol 85: 502-513, 2006.
    • (2006) Ann Hematol , vol.85 , pp. 502-513
    • Muller-Berndorff, H.1    Haas, P.S.2    Kunzmann, R.3    Schulte-Monting, J.A.4    Lubbert, M.5
  • 34
    • 66149097016 scopus 로고    scopus 로고
    • Simultaneous targeting of MCL1 and ABCB1 as a novel strategy to overcome drug resistance in human leukaemia
    • Ji M, Li J, Yu H, et al: Simultaneous targeting of MCL1 and ABCB1 as a novel strategy to overcome drug resistance in human leukaemia. Br J Haematol 145: 648-656, 2009.
    • (2009) Br J Haematol , vol.145 , pp. 648-656
    • Ji, M.1    Li, J.2    Yu, H.3
  • 35
    • 34948899300 scopus 로고    scopus 로고
    • Marrow angiogenesis-associated factors as prognostic biomarkers in patients with acute myelogenous leukaemia
    • Lee CY, Tien HF, Hu CY, Chou WC and Lin LI: Marrow angiogenesis- associated factors as prognostic biomarkers in patients with acute myelogenous leukaemia. Br J Cancer 97: 877-882, 2007.
    • (2007) Br J Cancer , vol.97 , pp. 877-882
    • Lee, C.Y.1    Tien, H.F.2    Hu, C.Y.3    Chou, W.C.A.4    Lin, L.I.5
  • 36
    • 57749110620 scopus 로고    scopus 로고
    • Notch inhibits expression of the Kruppel-like factor 4 tumor suppressor in the intestinal epithelium
    • Ghaleb AM, Aggarwal G, Bialkowska AB, Nandan MO and Yang VW: Notch inhibits expression of the Kruppel-like factor 4 tumor suppressor in the intestinal epithelium. Mol Cancer Res 6: 1920-1927, 2008.
    • (2008) Mol Cancer Res , vol.6 , pp. 1920-1927
    • Ghaleb, A.M.1    Aggarwal, G.2    Bialkowska, A.B.3    Nandan, M.O.A.4    Yang, V.W.5
  • 37
    • 77954423454 scopus 로고    scopus 로고
    • Notch signaling maintains proliferation and survival of the HL60 human promyelocytic leukemia cell line and promotes the phosphorylation of the Rb protein
    • Li GH, Fan YZ, Liu XW, et al: Notch signaling maintains proliferation and survival of the HL60 human promyelocytic leukemia cell line and promotes the phosphorylation of the Rb protein. Mol Cell Biochem 340: 7-14, 2010.
    • (2010) Mol Cell Biochem , vol.340 , pp. 7-14
    • Li, G.H.1    Fan, Y.Z.2    Liu, X.W.3
  • 38
    • 68049102052 scopus 로고    scopus 로고
    • Functional analysis of notch in the pathophysiology of leukemia
    • In Japanese
    • Tohda S: Functional analysis of notch in the pathophysiology of leukemia. Rinsho Byori 57: 351-356, 2009 (In Japanese).
    • (2009) Rinsho Byori , vol.57 , pp. 351-356
    • Tohda, S.1
  • 39
    • 78650082224 scopus 로고    scopus 로고
    • Prognostic impact of Notch ligands and receptors in nonsmall cell lung cancer: Coexpression of Notch-1 and vascular endothelial growth factor-A predicts poor survival
    • Donnem T, Andersen S, Al-Shibli K, Al-Saad S, Busund LT and Bremnes RM: Prognostic impact of Notch ligands and receptors in nonsmall cell lung cancer: coexpression of Notch-1 and vascular endothelial growth factor-A predicts poor survival. Cancer 116: 5676-5685, 2010.
    • (2010) Cancer , vol.116 , pp. 5676-5685
    • Donnem, T.1    Andersen, S.2    Al-Shibli, K.3    Al-Saad, S.4    Busund, L.T.A.5    Bremnes, R.M.6
  • 40
    • 24944506696 scopus 로고    scopus 로고
    • High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival
    • Reedijk M, Odorcic S, Chang L, et al: High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival. Cancer Res 65: 8530-8537, 2005.
    • (2005) Cancer Res , vol.65 , pp. 8530-8537
    • Reedijk, M.1    Odorcic, S.2    Chang, L.3
  • 41
    • 44649129124 scopus 로고    scopus 로고
    • Association of low expression of notch-1 and jagged-1 in human papillary bladder cancer and shorter survival
    • Shi TP, Xu H, Wei JF, et al: Association of low expression of notch-1 and jagged-1 in human papillary bladder cancer and shorter survival. J Urol 180: 361-366, 2008.
    • (2008) J Urol , vol.180 , pp. 361-366
    • Shi, T.P.1    Xu, H.2    Wei, J.F.3
  • 42
    • 41649088181 scopus 로고    scopus 로고
    • Modulation of VEGF signalling output by the Notch pathway
    • Siekmann AF, Covassin L and Lawson ND: Modulation of VEGF signalling output by the Notch pathway. Bioessays 30: 303-313, 2008.
    • (2008) Bioessays , vol.30 , pp. 303-313
    • Siekmann, A.F.1    Covassin, L.A.2    Lawson, N.D.3
  • 43
    • 31544448010 scopus 로고    scopus 로고
    • Up-regulation of the Notch ligand Delta-like 4 inhibits VEGFinduced endothelial cell function
    • Williams CK, Li JL, Murga M, Harris AL and Tosato G: Up-regulation of the Notch ligand Delta-like 4 inhibits VEGFinduced endothelial cell function. Blood 107: 931-939, 2006.
    • (2006) Blood , vol.107 , pp. 931-939
    • Williams, C.K.1    Li, J.L.2    Murga, M.3    Harris, A.L.A.4    Tosato, G.5
  • 44
    • 4544373099 scopus 로고    scopus 로고
    • Autocrine pathway of angiopoietins-Tie2 system in AML cells: Association with phosphatidyl-inositol 3 kinase
    • Wakabayashi M, Miwa H, Shikami M, et al: Autocrine pathway of angiopoietins-Tie2 system in AML cells: association with phosphatidyl-inositol 3 kinase. Hematol J 5: 353-360, 2004.
    • (2004) Hematol J , vol.5 , pp. 353-360
    • Wakabayashi, M.1    Miwa, H.2    Shikami, M.3
  • 45
    • 0042744837 scopus 로고    scopus 로고
    • Survival of acute myeloid leukemia cells requires PI3 kinase activation
    • Xu Q, Simpson SE, Scialla TJ, Bagg A and Carroll M: Survival of acute myeloid leukemia cells requires PI3 kinase activation. Blood 102: 972-980, 2003.
    • (2003) Blood , vol.102 , pp. 972-980
    • Xu, Q.1    Simpson, S.E.2    Scialla, T.J.3    Bagg, A.A.4    Carroll, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.