메뉴 건너뛰기




Volumn 145, Issue 5, 2009, Pages 648-656

Simultaneous targeting of MCL1 and ABCB1 as a novel strategy to overcome drug resistance in human leukaemia

Author keywords

ABCB1; Drug resistance; Leukaemia; MCL1; RNA interference

Indexed keywords

DOXORUBICIN; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN MCL 1; SHORT HAIRPIN RNA;

EID: 66149097016     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2009.07678.x     Document Type: Article
Times cited : (23)

References (30)
  • 3
    • 35748937651 scopus 로고    scopus 로고
    • Upregulation of multi drug resistance genes in doxorubicin resistant human acute myelogeneous leukemia cells and reversal of the resistance
    • DOI 10.1080/10245330701562535, PII 781128321
    • Baran, Y., Gür, B., Kaya, P., Ural, A.U., Avcu, F. Gündüz, U. (2007) Upregulation of multi drug resistance genes in doxorubicin resistant human acute myelogeneous leukemia cells and reversal of the resistance. Hematology, 12, 511 517. (Pubitemid 350048061)
    • (2007) Hematology , vol.12 , Issue.6 , pp. 511-517
    • Baran, Y.1    Gur, B.2    Kaya, P.3    Ural, A.U.4    Avcu, F.5    Gunduz, U.6
  • 6
    • 34250327394 scopus 로고    scopus 로고
    • Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3β activity and associates with poor prognosis in human breast cancer
    • DOI 10.1158/0008-5472.CAN-06-1788
    • Ding, Q., He, X., Xia, W., Hsu, J.M., Chen, C.T., Li, L.Y., Lee, D.F., Yang, J.Y., Xie, X., Liu, J.C. Hung, M.C. (2007) Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3beta activity and associates with poor prognosis in human breast cancer. Cancer Research, 67, 4564 4571. (Pubitemid 46910160)
    • (2007) Cancer Research , vol.67 , Issue.10 , pp. 4564-4571
    • Ding, Q.1    He, X.2    Xia, W.3    Hsu, J.-M.4    Chen, C.-T.5    Li, L.-Y.6    Lee, D.-F.7    Yang, J.-Y.8    Xie, X.9    Liu, J.-C.10    Hung, M.-C.11
  • 7
    • 33846914830 scopus 로고    scopus 로고
    • The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages
    • DOI 10.1182/blood-2006-03-013771
    • Dzhagalov, I., St John, A. He, Y.W. (2007) The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages. Blood, 109, 1620 1626. (Pubitemid 46239596)
    • (2007) Blood , vol.109 , Issue.4 , pp. 1620-1626
    • Dzhagalov, I.1    St. John, A.2    He, Y.-W.3
  • 8
    • 34347256390 scopus 로고    scopus 로고
    • Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma
    • DOI 10.1158/0008-5472.CAN-06-4322
    • Gomez-Bougie, P., Wuillème-Toumi, S., Ménoret, E., Trichet, V., Robillard, N., Philippe, M., Bataille, R. Amiot, M. (2007) Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma. Cancer Research, 67, 5418 5424. (Pubitemid 46997282)
    • (2007) Cancer Research , vol.67 , Issue.11 , pp. 5418-5424
    • Gomez-Bougie, P.1    Wuilleme-Toumi, S.2    Menoret, E.3    Trichet, V.4    Robillard, N.5    Philippe, M.6    Bataille, R.7    Amiot, M.8
  • 9
    • 40649100954 scopus 로고    scopus 로고
    • MDR1 and BCRP1 expression in leukemic progenitors correlates with chemotherapy response in acute myeloid leukemia
    • Ho, M.M., Hogge, D.E. Ling, V. (2008) MDR1 and BCRP1 expression in leukemic progenitors correlates with chemotherapy response in acute myeloid leukemia. Experimental Hematology, 36, 433 442.
    • (2008) Experimental Hematology , vol.36 , pp. 433-442
    • Ho, M.M.1    Hogge, D.E.2    Ling, V.3
  • 10
    • 34247511009 scopus 로고    scopus 로고
    • Mcl-1 is a relevant therapeutic target in acute and chronic lymphoid malignancies: Down-regulation enhances rituximab-mediated apoptosis and complement-dependent cytotoxicity
    • DOI 10.1158/1078-0432.CCR-06-2294
    • Hussain, S.R., Cheney, C.M., Johnson, A.J., Lin, T.S., Grever, M.R., Caligiuri, M.A., Lucas, D.M. Byrd, J.C. (2007) Mcl-1 is a relevant therapeutic target in acute and chronic lymphoid malignancies: down-regulation enhances rituximab-mediated apoptosis and complement-dependent cytotoxicity. Clinical Cancer Research, 13, 2144 2150. (Pubitemid 46649884)
    • (2007) Clinical Cancer Research , vol.13 , Issue.7 , pp. 2144-2150
    • Hussain, S.-R.A.1    Cheney, C.M.2    Johnson, A.J.3    Lin, T.S.4    Grever, M.R.5    Caligiuri, M.A.6    Lucas, D.M.7    Byrd, J.C.8
  • 11
    • 42349095198 scopus 로고    scopus 로고
    • Downregulation of Mcl-1 potentiates HDACi-mediated apoptosis in leukemic cells
    • Inoue, S., Walewska, R., Dyer, M.J. Cohen, G.M. (2008) Downregulation of Mcl-1 potentiates HDACi-mediated apoptosis in leukemic cells. Leukemia, 22, 819 825.
    • (2008) Leukemia , vol.22 , pp. 819-825
    • Inoue, S.1    Walewska, R.2    Dyer, M.J.3    Cohen, G.M.4
  • 12
    • 43149117910 scopus 로고    scopus 로고
    • Mechanism of synergy of N-(4-Hydroxyphenyl) retinamide and ABT-737 in acute lymphoblastic leukemia cell line: Mcl-1 inactivation
    • Kang, M.H., Wan, Z., Kang, Y.H., Sposto, R. Reynolds, C.P. (2008) Mechanism of synergy of N-(4-Hydroxyphenyl) retinamide and ABT-737 in acute lymphoblastic leukemia cell line: Mcl-1 inactivation. Journal of the National Cancer Institute, 100, 580 595.
    • (2008) Journal of the National Cancer Institute , vol.100 , pp. 580-595
    • Kang, M.H.1    Wan, Z.2    Kang, Y.H.3    Sposto, R.4    Reynolds, C.P.5
  • 13
    • 0032006805 scopus 로고    scopus 로고
    • Elevated expression of the apoptotic regulator Mcl-1 at the time of leukemic relapse
    • Kaufmann, S.H., Karp, J.E., Svingen, P.A., Krajewski, S., Burke, P.J., Gore, S.D. Reed, J.C. (1998) Elevated expression of the apoptotic regulator Mcl-1 at the time of leukemic relapse. Blood, 91, 991 1000. (Pubitemid 28078303)
    • (1998) Blood , vol.91 , Issue.3 , pp. 991-1000
    • Kaufmann, S.H.1    Karp, J.E.2    Svingen, P.A.3    Krajewski, S.4    Burke, P.J.5    Gore, S.D.6    Reed, J.C.7
  • 15
    • 0031005627 scopus 로고    scopus 로고
    • Acute myeloid leukemia in the elderly: assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group study
    • Leith, C.P., Kopecky, K.J., Godwin, J., McConnell, T., Slovak, M.L., Chen, I.M., Head, D.R., Appelbaum, F.R. Willman, C.L. (1997) Acute myeloid leukemia in the elderly: assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group study. Blood, 89, 3323 3329.
    • (1997) Blood , vol.89 , pp. 3323-3329
    • Leith, C.P.1    Kopecky, K.J.2    Godwin, J.3    McConnell, T.4    Slovak, M.L.5    Chen, I.M.6    Head, D.R.7    Appelbaum, F.R.8    Willman, C.L.9
  • 16
    • 0033179095 scopus 로고    scopus 로고
    • Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia. A Southwest Oncology Group study
    • Leith, C.P., Kopecky, K.J., Chen, I.M., Eijdems, L., Slovak, M.L., McConnell, T.S., Head, D.R., Weick, J., Grever, M.R., Appelbaum, F.R. Willman, C.L. (1999) Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia: a Southwest Oncology Group Study. Blood, 94, 1086 1099. (Pubitemid 29361842)
    • (1999) Blood , vol.94 , Issue.3 , pp. 1086-1099
    • Leith, C.P.1    Kopecky, K.J.2    Chen, I.-M.3    Eijdems, L.4    Slovak, M.L.5    McConnell, T.S.6    Head, D.R.7    Weick, J.8    Grever, M.R.9    Appelbaum, F.R.10    Willman, C.L.11
  • 17
    • 0034283981 scopus 로고    scopus 로고
    • Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells
    • Moulding, D.A., Giles, R.V., Spiller, D.G., White, M.R., Tidd, D.M. Edwards, S.W. (2000) Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells. Blood, 96, 1756 1763. (Pubitemid 30661059)
    • (2000) Blood , vol.96 , Issue.5 , pp. 1756-1763
    • Moulding, D.A.1    Giles, R.V.2    Spiller, D.G.3    White, M.R.H.4    Tidd, D.M.5    Edwards, S.W.6
  • 19
    • 0348148880 scopus 로고    scopus 로고
    • Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1
    • DOI 10.1038/nature02067
    • Opferman, J.T., Letai, A., Beard, C., Sorcinelli, M.D., Ong, C.C. Korsmeyer, S.J. (2003) Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1. Nature, 426, 671 676. (Pubitemid 38009376)
    • (2003) Nature , vol.426 , Issue.6967 , pp. 671-676
    • Opferman, J.T.1    Letai, A.2    Beard, C.3    Sorcinelli, M.D.4    Ong, C.C.5    Korsmeyer, S.J.6
  • 20
    • 13844319184 scopus 로고    scopus 로고
    • Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells
    • DOI 10.1126/science.1106114
    • Opferman, J.T., Iwasaki, H., Ong, C.C., Suh, H., Mizuno, S., Akashi, K. Korsmeyer, S.J. (2005) Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells. Science, 307, 1101 1104. (Pubitemid 40262114)
    • (2005) Science , vol.307 , Issue.5712 , pp. 1101-1104
    • Opferman, J.T.1    Iwasaki, H.2    Ong, C.C.3    Suh, H.4    Mizuno, S.-I.5    Akashi, K.6    Korsmeyer, S.J.7
  • 22
    • 0036849351 scopus 로고    scopus 로고
    • P-glycoprotein inhibits caspase-8 activation but not formation of the death inducing signal complex (disc) following Fas ligation
    • DOI 10.1038/sj.cdd.4401081
    • Ruefli, A.A., Tainton, K.M., Darcy, P.K., Smyth, M.J. Johnstone, R.W. (2002) P-glycoprotein inhibits caspase-8 activation but not formation of the death inducing signal complex (disc) following Fas ligation. Cell Death and Differentiation, 9, 1266 1272. (Pubitemid 35331774)
    • (2002) Cell Death and Differentiation , vol.9 , Issue.11 , pp. 1266-1272
    • Ruefli, A.A.1    Tainton, K.M.2    Darcy, P.K.3    Smyth, M.J.4    Johnstone, R.W.5
  • 23
    • 0347416908 scopus 로고    scopus 로고
    • Mcl-1 and Bcl-2/Bax Ratio Are Associated with Treatment Response but Not with Rai Stage in B-Cell Chronic Lymphocytic Leukemia
    • DOI 10.1002/ajh.10453
    • Saxena, A., Viswanathan, S., Moshynska, O., Tandon, P., Sankaran, K. Sheridan, D.P. (2004) Mcl-1 and Bcl-2/Bax ratio are associated with treatment response but not with Rai stage in B-cell chronic lymphocytic leukemia. American Journal of Hematology, 75, 22 33. (Pubitemid 38040164)
    • (2004) American Journal of Hematology , vol.75 , Issue.1 , pp. 22-33
    • Saxena, A.1    Viswanathan, S.2    Moshynska, O.3    Tandon, P.4    Sankaran, K.5    Sheridan, D.P.6
  • 24
    • 13444252391 scopus 로고    scopus 로고
    • MDR1 and MRP1 gene expression are independent predictors for treatment outcome in adult acute myeloid leukaemia
    • DOI 10.1111/j.1365-2141.2004.05319.x
    • Schaich, M., Soucek, S., Thiede, C., Ehninger, G., Illmer, T. SHG AML96 Study Group 2005) MDR1 and MRP1 gene expression are independent predictors for treatment outcome in adult acute myeloid leukaemia. British Journal of Haematology, 128, 324 332. (Pubitemid 40216154)
    • (2005) British Journal of Haematology , vol.128 , Issue.3 , pp. 324-332
    • Schaich, M.1    Soucek, S.2    Thiede, C.3    Ehninger, G.4    Illmer, T.5
  • 25
    • 33750051632 scopus 로고    scopus 로고
    • Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction
    • Schulze-Bergkamen, H., Fleischer, B., Schuchmann, M., Weber, A., Weinmann, A., Krammer, P.H. Galle, P.R. (2006) Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction. BMC Cancer, 6, 232.
    • (2006) BMC Cancer , vol.6 , pp. 232
    • Schulze-Bergkamen, H.1    Fleischer, B.2    Schuchmann, M.3    Weber, A.4    Weinmann, A.5    Krammer, P.H.6    Galle, P.R.7
  • 26
    • 0033519705 scopus 로고    scopus 로고
    • Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
    • DOI 10.1038/20959
    • Shimizu, S., Narita, M. Tsujimoto, Y. (1999) Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature, 399, 483 487. (Pubitemid 29258855)
    • (1999) Nature , vol.399 , Issue.6735 , pp. 483-487
    • Shimizu, S.1    Narita, M.2    Tsujimoto, Y.3
  • 27
    • 33745197795 scopus 로고    scopus 로고
    • Multidrug resistance and stem cells in acute myeloid leukemia
    • DOI 10.1158/1078-0432.CCR-06-0655
    • Sikic, B.I. (2006) Multidrug resistance and stem cells in acute myeloid leukemia. Clinical Cancer Research, 12, 3231 3232. (Pubitemid 43910862)
    • (2006) Clinical Cancer Research , vol.12 , Issue.11 I , pp. 3231-3232
    • Sikic, B.I.1
  • 28
    • 25144453314 scopus 로고    scopus 로고
    • Mcl-1 regulates survival and sensitivity to diverse apoptotic stimuli in human non-small cell lung cancer cells
    • Song, L., Coppola, D., Livingston, S., Cress, D. Haura, E.B. (2005) Mcl-1 regulates survival and sensitivity to diverse apoptotic stimuli in human non-small cell lung cancer cells. Cancer Biology & Therapy, 4, 267 276. (Pubitemid 41351285)
    • (2005) Cancer Biology and Therapy , vol.4 , Issue.3 , pp. 267-276
    • Song, L.1    Coppola, D.2    Livingston, S.3    Cress, D.4    Haura, E.B.5
  • 29
    • 23644455476 scopus 로고    scopus 로고
    • Drug therapy for acute myeloid leukemia
    • DOI 10.1182/blood-2005-01-0178
    • Tallman, M.S., Gilliland, D.G. Rowe, J.M. (2005) Drug therapy for acute myeloid leukemia. Blood, 106, 1154 1163. (Pubitemid 41130866)
    • (2005) Blood , vol.106 , Issue.4 , pp. 1154-1163
    • Tallman, M.S.1    Gilliland, D.G.2    Rowe, J.M.3
  • 30
    • 2442663096 scopus 로고    scopus 로고
    • Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells
    • DOI 10.1158/0008-5472.CAN-03-2770
    • Taniai, M., Grambihler, A., Hiquchi, H., Werneburg, N., Bronk, S.F., Farrugia, D.J., Kaufmann, S.H. Gores, G.J. (2004) Mcl-1 mediates tumor necrosis fator-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells. Cancer Research, 64, 3517 3524. (Pubitemid 38657926)
    • (2004) Cancer Research , vol.64 , Issue.10 , pp. 3517-3524
    • Taniai, M.1    Grambihler, A.2    Higuchi, H.3    Werneburg, N.4    Bronk, S.F.5    Farrugia, D.J.6    Kaufmann, S.H.7    Gores, G.J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.