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Volumn 13, Issue 14, 2012, Pages 2137-2145

Crystal Structures of BapA Complexes with β-Lactam-Derived Inhibitors Illustrate Substrate Specificity and Enantioselectivity of β-Aminopeptidases

(9) Heck, Tobias a,d Merz, Tobias b Reimer, Artur a Seebach, Dieter c Rentsch, Daniel d Briand, Christophe b Grütter, Markus G b Kohler, Hans Peter E a Geueke, Birgit a

a SWISS FEDERAL INSTITUTE OF AQUATIC SCIENCE AND TECHNOLOGY (Switzerland)

b UNIVERSITY OF ZURICH (Switzerland)

c ETH ZURICH (Switzerland)

d SWISS FEDERAL LABORATORIES FOR MATERIALS SCIENCE AND TECHNOLOGY (Switzerland)

Author keywords

AEBSF; Ampicillin; Beta peptides; Ntn hydrolases; Pefabloc SC

Indexed keywords

4 (2 AMINOETHYL)BENZENESULFONYLFLUORIDE; AMINOPEPTIDASE; AMPICILLIN; BETA AMINOPEPTIDASE INHIBITOR; GLUTAMIC ACID; PENICILLOIC ACID; PEPTIDE HYDROLASE INHIBITOR; PROTEIN BAPA; PROTEIN DMPA; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BACTERIUM; COMPLEX FORMATION; CRYSTAL STRUCTURE; DRUG PROTEIN BINDING; ENANTIOSELECTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; ENZYME STRUCTURE; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN QUATERNARY STRUCTURE; SPHINGOSINICELLA XENOPEPTIDILYTICA; STEREOSPECIFICITY;

AMINOPEPTIDASES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAMS; BINDING SITES; BIOCATALYSIS; CRYSTALLOGRAPHY, X-RAY; PROTEIN STRUCTURE, TERTIARY; SERINE PROTEINASE INHIBITORS; SPHINGOMONADACEAE; STEREOISOMERISM; SUBSTRATE SPECIFICITY; SULFONES;

SPHINGOSINICELLA;

EID: 84866443360 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.201200393 Document Type: Article

Times cited : (6)

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