Differential roles of GABA a receptor subtypes in benzodiazepine-induced enhancement of brain-stimulation reward

Neuropsychopharmacology

Volumn 37, Issue 11, 2012, Pages 2531-2540

  Reynolds, Lauren M ^a,b   Engin, Elif ^a,b   Tantillo, Gabriella ^a,b   Lau, Hew Mun ^a,b   Muschamp, John W ^a,b   Carlezon, William A ^a,b   Rudolph, Uwe ^a,b  

^a MCLEAN HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

subunit; benzodiazepine; GABAA receptor; intracranial self stimulation; point mutation; zolpidem

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ARGININE; BENZODIAZEPINE; COCAINE; DIAZEPAM; HISTIDINE; NALPHA [3 MORPHOLINOCARBONYL 2 (1 NAPHTHYLMETHYL)PROPIONYL]HISTIDINE N [1 CYCLOHEXYLMETHYL 2 HYDROXY 3 (1 METHYL 5 TETRAZOLYLTHIO)PROPYL]AMIDE; RECEPTOR SUBUNIT; ZOLPIDEM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEPTH STIMULATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABUSE; DRUG EFFECT; GENOTYPE; MALE; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; REWARD; WILD TYPE;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BENZODIAZEPINES; BRAIN; COCAINE; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; GABA AGENTS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; POINT MUTATION; PROTEIN SUBUNITS; RECEPTORS, GABA-A; REINFORCEMENT SCHEDULE; REWARD; SELF STIMULATION;

EID: 84866430017     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2012.115     Document Type: Article

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